Homo sapiens

204 known processes

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

(Aliases: p21-Rac1,MGC111543,TC-25)

RAC1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
establishment or maintenance of cytoskeleton polarity GO:0030952 3 1.000
Fly
positive regulation of rho gtpase activity GO:0032321 56 1.000
Human
positive regulation of lamellipodium assembly GO:0010592 9 1.000
gtp metabolic process GO:0046039 239 1.000
Human Mouse Rat Worm Fly
ras protein signal transduction GO:0007265 73 1.000
Human Fly
small gtpase mediated signal transduction GO:0007264 78 1.000
Human Mouse Worm Fly
rho protein signal transduction GO:0007266 26 1.000
Human Fly
positive regulation of rac gtpase activity GO:0032855 31 1.000
Human
lymphocyte aggregation GO:0071593 1 1.000
Human
positive regulation of lamellipodium organization GO:1902745 12 1.000
positive regulation of ras gtpase activity GO:0032320 117 1.000
Human
nucleoside catabolic process GO:0009164 408 1.000
Human Mouse Rat Worm Fly
purine ribonucleotide catabolic process GO:0009154 404 1.000
Human Mouse Rat Worm Fly
glycosyl compound catabolic process GO:1901658 413 1.000
Human Mouse Rat Worm Fly
positive regulation of gtpase activity GO:0043547 166 1.000
Human
anterior posterior axis specification GO:0009948 2 1.000
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 1.000
Human Mouse Rat Worm Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 1.000
Human
ribonucleoside catabolic process GO:0042454 406 1.000
Human Mouse Rat Worm Fly
regulation of nucleotide metabolic process GO:0006140 269 1.000
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 1.000
Human
guanosine containing compound catabolic process GO:1901069 239 1.000
Human Mouse Rat Worm Fly
regulation of rho gtpase activity GO:0032319 66 1.000
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 1.000
Fly
purine ribonucleoside catabolic process GO:0046130 398 1.000
Human Mouse Rat Worm Fly
regulation of stress fiber assembly GO:0051492 32 1.000
tripartite regional subdivision GO:0007351 2 1.000
Fly
regulation of actin cytoskeleton organization GO:0032956 116 1.000
gtp catabolic process GO:0006184 237 1.000
Human Mouse Rat Worm Fly
regulation of rho protein signal transduction GO:0035023 79 1.000
Human
oocyte development GO:0048599 1 1.000
Fly
actin filament based process GO:0030029 224 1.000
purine ribonucleoside triphosphate metabolic process GO:0009205 411 1.000
Human Mouse Rat Worm Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 1.000
Human Mouse Rat Worm Fly
positive regulation of nucleotide catabolic process GO:0030813 185 1.000
Human
organophosphate catabolic process GO:0046434 430 1.000
Human Mouse Rat Worm Fly
nucleoside phosphate catabolic process GO:1901292 412 1.000
Human Mouse Rat Worm Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 1.000
Human Mouse Rat Worm Fly
nucleoside triphosphate catabolic process GO:0009143 394 1.000
Human Mouse Rat Worm Fly
regulation of nucleoside metabolic process GO:0009118 209 1.000
Human
positive regulation of actin filament bundle assembly GO:0032233 25 1.000
guanosine containing compound metabolic process GO:1901068 244 1.000
Human Mouse Rat Worm Fly
hair follicle morphogenesis GO:0031069 2 1.000
positive regulation of gtp catabolic process GO:0033126 166 1.000
Human
purine nucleoside catabolic process GO:0006152 398 1.000
Human Mouse Rat Worm Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 1.000
Human Mouse Rat Worm Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 1.000
Human
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 1.000
Human
nucleotide catabolic process GO:0009166 408 1.000
Human Mouse Rat Worm Fly
regulation of purine nucleotide metabolic process GO:1900542 264 1.000
Human
purine ribonucleoside metabolic process GO:0046128 437 1.000
Human Mouse Rat Worm Fly
regulation of ras gtpase activity GO:0032318 128 0.999
Human
ribonucleotide catabolic process GO:0009261 405 0.999
Human Mouse Rat Worm Fly
taxis GO:0042330 157 0.999
rac protein signal transduction GO:0016601 12 0.999
Human
oocyte differentiation GO:0009994 2 0.999
Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.999
Human
lamellipodium organization GO:0097581 30 0.999
purine containing compound catabolic process GO:0072523 411 0.999
Human Mouse Rat Worm Fly
positive regulation of cellular component organization GO:0051130 376 0.999
regulation of cysteine type endopeptidase activity GO:2000116 127 0.999
actin filament organization GO:0007015 128 0.999
female gamete generation GO:0007292 2 0.999
Fly
regulation of actin filament bundle assembly GO:0032231 36 0.999
oogenesis GO:0048477 2 0.998
Fly
establishment or maintenance of cell polarity GO:0007163 31 0.998
Fly
regulation of cell projection organization GO:0031344 107 0.998
embryonic axis specification GO:0000578 5 0.998
Fly
positive regulation of organelle organization GO:0010638 195 0.998
single organism cellular localization GO:1902580 332 0.998
Human Mouse Fly
intracellular mrna localization GO:0008298 1 0.998
Fly
positive regulation of catabolic process GO:0009896 310 0.997
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.997
positive regulation of synapse structural plasticity GO:0051835 2 0.997
ribonucleoside triphosphate metabolic process GO:0009199 412 0.997
Human Mouse Rat Worm Fly
organelle assembly GO:0070925 176 0.997
regulation of cytoskeleton organization GO:0051493 177 0.997
positive regulation of hydrolase activity GO:0051345 331 0.997
Human
positive regulation of transferase activity GO:0051347 227 0.997
Mouse Fly
cell projection assembly GO:0030031 126 0.997
actomyosin structure organization GO:0031032 59 0.996
maintenance of cell polarity GO:0030011 2 0.996
actin filament bundle organization GO:0061572 54 0.996
regulation of peptidase activity GO:0052547 180 0.996
regulation of gtp catabolic process GO:0033124 180 0.996
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.996
response to nitrogen compound GO:1901698 184 0.996
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.995
Human Mouse Rat Worm Fly
purine nucleotide catabolic process GO:0006195 405 0.995
Human Mouse Rat Worm Fly
anterior posterior axis specification embryo GO:0008595 2 0.995
Fly
modification dependent protein catabolic process GO:0019941 209 0.995
positive regulation of cytoskeleton organization GO:0051495 83 0.995
response to organonitrogen compound GO:0010243 156 0.995
Human
microtubule cytoskeleton organization GO:0000226 176 0.994
Human Fly
actin cytoskeleton organization GO:0030036 207 0.994
regulation of cellular amine metabolic process GO:0033238 11 0.993
regulation of protein localization GO:0032880 296 0.993
Human
regulation of endopeptidase activity GO:0052548 170 0.993
regulation of respiratory burst GO:0060263 8 0.993
response to peptidoglycan GO:0032494 3 0.993
embryonic pattern specification GO:0009880 5 0.992
Fly
cell junction assembly GO:0034329 67 0.991
cell development GO:0048468 328 0.991
actin filament bundle assembly GO:0051017 54 0.990
lamellipodium assembly GO:0030032 26 0.990
negative regulation of cellular protein metabolic process GO:0032269 353 0.990
cell migration involved in gastrulation GO:0042074 1 0.990
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.990
Fly
positive regulation of stress fiber assembly GO:0051496 22 0.990
biological adhesion GO:0022610 331 0.990
regulation of protein localization to plasma membrane GO:1903076 40 0.989
Human
segmentation GO:0035282 4 0.989
Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.989
cell chemotaxis GO:0060326 112 0.989
positive regulation of protein kinase activity GO:0045860 190 0.988
Fly
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.988
stress fiber assembly GO:0043149 40 0.988
axis specification GO:0009798 12 0.987
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.987
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.987
regulation of cellular component biogenesis GO:0044087 281 0.986
regulation of neurotransmitter secretion GO:0046928 3 0.984
glial cell migration GO:0008347 4 0.982
Fly
cellular macromolecular complex assembly GO:0034622 324 0.982
Mouse
protein modification by small protein conjugation GO:0032446 342 0.981
regulation of actin filament based process GO:0032970 141 0.981
blastoderm segmentation GO:0007350 2 0.980
Fly
cell adhesion GO:0007155 325 0.980
ameboidal type cell migration GO:0001667 135 0.979
Fly
regulation of cell cycle GO:0051726 393 0.979
Human Fly
response to other organism GO:0051707 261 0.978
Fly
protein catabolic process GO:0030163 325 0.978
innate immune response GO:0045087 178 0.977
Fly
neutrophil chemotaxis GO:0030593 24 0.977
regulation of actin filament polymerization GO:0030833 50 0.976
Mouse
motor neuron axon guidance GO:0008045 2 0.975
Worm Fly
regulation of gtpase activity GO:0043087 180 0.972
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.971
neuroblast proliferation GO:0007405 4 0.967
filopodium assembly GO:0046847 18 0.967
Human Fly
negative regulation of cell death GO:0060548 345 0.967
negative regulation of protein metabolic process GO:0051248 391 0.966
intracellular protein transport GO:0006886 270 0.966
cytokinesis GO:0000910 96 0.966
Human
salivary gland morphogenesis GO:0007435 4 0.965
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.965
pattern specification process GO:0007389 43 0.965
Fly
endomembrane system organization GO:0010256 196 0.965
Human Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.965
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.964
regulation of cell projection assembly GO:0060491 47 0.964
apoptotic signaling pathway GO:0097190 268 0.963
regulation of cell morphogenesis GO:0022604 153 0.963
single organismal cell cell adhesion GO:0016337 148 0.962
Human
regulation of transferase activity GO:0051338 355 0.960
Mouse Fly
neurotransmitter secretion GO:0007269 4 0.960
anterior posterior pattern specification GO:0009952 9 0.959
Fly
leukocyte migration GO:0050900 107 0.958
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.958
digestive tract morphogenesis GO:0048546 56 0.958
Fly
regulation of ras protein signal transduction GO:0046578 155 0.957
Human
transmembrane transport GO:0055085 399 0.957
cell morphogenesis involved in differentiation GO:0000904 144 0.956
negative regulation of apoptotic process GO:0043066 316 0.956
response to biotic stimulus GO:0009607 276 0.954
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.954
Human
cellular ketone metabolic process GO:0042180 80 0.952
regulation of metalloenzyme activity GO:0048552 3 0.952
regulation of anatomical structure morphogenesis GO:0022603 286 0.952
protein processing GO:0016485 226 0.950
positive regulation of nucleoside metabolic process GO:0045979 186 0.947
Human
positive regulation of cell differentiation GO:0045597 211 0.947
negative regulation of phosphorus metabolic process GO:0010563 267 0.943
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.941
granulocyte chemotaxis GO:0071621 37 0.941
mitotic cell cycle process GO:1903047 286 0.939
regulation of lamellipodium morphogenesis GO:2000392 4 0.938
negative regulation of interleukin 23 production GO:0032707 1 0.938
negative regulation of establishment of protein localization to plasma membrane GO:0090005 9 0.938
Human
protein localization to membrane GO:0072657 160 0.935
Human Mouse
response to external biotic stimulus GO:0043207 261 0.934
Fly
negative regulation of protein processing GO:0010955 142 0.933
regulation of protein kinase activity GO:0045859 289 0.932
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.931
leukocyte aggregation GO:0070486 8 0.931
Human
regulation of cell adhesion GO:0030155 166 0.929
cortical cytoskeleton organization GO:0030865 9 0.927
Human Fly
regulation of granulocyte chemotaxis GO:0071622 16 0.925
cell projection organization GO:0030030 252 0.925
cellular protein catabolic process GO:0044257 261 0.924
morphogenesis of an epithelium GO:0002009 60 0.924
Mouse Fly
cellular response to nitrogen compound GO:1901699 144 0.922
Human
cellular response to oxygen containing compound GO:1901701 276 0.917
Human
central nervous system development GO:0007417 123 0.913
Human Mouse Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.912
Human
positive regulation of developmental process GO:0051094 314 0.911
regulation of cell differentiation GO:0045595 393 0.911
negative regulation of endopeptidase activity GO:0010951 84 0.906
response to oxygen containing compound GO:1901700 369 0.906
Human
positive regulation of transport GO:0051050 336 0.906
Human
tissue morphogenesis GO:0048729 96 0.902
Mouse Fly
regulation of cell development GO:0060284 161 0.902
response to bacterium GO:0009617 144 0.900
Fly
establishment of cell polarity GO:0030010 22 0.896
Fly
cellular amine metabolic process GO:0044106 41 0.894
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.894
regulation of interleukin 23 production GO:0032667 5 0.893
regulation of cell motility GO:2000145 299 0.890
establishment of protein localization to plasma membrane GO:0090002 68 0.889
Human
regulation of wound healing GO:0061041 56 0.888
Fly
negative regulation of catalytic activity GO:0043086 335 0.886
negative regulation of protein modification process GO:0031400 200 0.886
muscle structure development GO:0061061 98 0.886
Fly
negative regulation of apoptotic signaling pathway GO:2001234 97 0.885
granulocyte migration GO:0097530 40 0.884
regulation of cell migration GO:0030334 289 0.882
plasma membrane organization GO:0007009 115 0.880
Human Mouse
positive regulation of cell development GO:0010720 92 0.874
tube morphogenesis GO:0035239 95 0.872
Fly
myeloid leukocyte migration GO:0097529 62 0.868
cell division GO:0051301 168 0.868
Human
positive regulation of cell death GO:0010942 263 0.867
organ morphogenesis GO:0009887 147 0.867
Mouse Fly
cell junction organization GO:0034330 79 0.866
negative regulation of peptidase activity GO:0010466 91 0.864
microtubule based process GO:0007017 210 0.854
Human Fly
activation of ras gtpase activity GO:0032856 15 0.853
Human
protein localization to organelle GO:0033365 280 0.851
positive regulation of leukocyte chemotaxis GO:0002690 38 0.848
pseudopodium organization GO:0031268 8 0.845
Human
organelle fission GO:0048285 149 0.838
cell competition in a multicellular organism GO:0035212 1 0.833
Fly
positive regulation of neutrophil chemotaxis GO:0090023 7 0.832
cortical actin cytoskeleton organization GO:0030866 9 0.832
Human Fly
neuroblast division GO:0055057 1 0.820
positive regulation of protein phosphorylation GO:0001934 313 0.817
dephosphorylation GO:0016311 209 0.816
cell matrix adhesion GO:0007160 85 0.816
neuron projection extension GO:1990138 14 0.816
Worm Fly
positive regulation of programmed cell death GO:0043068 249 0.814
rna localization GO:0006403 41 0.812
Fly
regulation of leukocyte chemotaxis GO:0002688 46 0.810
positive regulation of cytokinesis GO:0032467 29 0.808
Human
establishment or maintenance of neuroblast polarity GO:0045196 1 0.807
membrane organization GO:0061024 292 0.806
Human Mouse Worm
epithelium development GO:0060429 227 0.806
Mouse Fly
regulation of lamellipodium organization GO:1902743 19 0.803
establishment of protein localization to membrane GO:0090150 121 0.802
Human
positive regulation of granulocyte chemotaxis GO:0071624 9 0.801
positive regulation of metalloenzyme activity GO:0048554 2 0.801
positive regulation of apoptotic signaling pathway GO:2001235 70 0.801
regulation of neutrophil chemotaxis GO:0090022 10 0.795
positive regulation of cell projection organization GO:0031346 64 0.794
cellular component morphogenesis GO:0032989 314 0.793
cellular macromolecule catabolic process GO:0044265 380 0.791
regulation of dendrite morphogenesis GO:0048814 11 0.791
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.790
Human
establishment of protein localization to organelle GO:0072594 172 0.786
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.783
protein maturation GO:0051604 233 0.783
positive regulation of cellular amine metabolic process GO:0033240 7 0.782
positive regulation of glucose transport GO:0010828 17 0.779
Human
ruffle organization GO:0031529 18 0.777
cell substrate junction assembly GO:0007044 35 0.773
asymmetric neuroblast division GO:0055059 1 0.772
regulation of protein targeting GO:1903533 91 0.770
regulation of substrate adhesion dependent cell spreading GO:1900024 19 0.768
single organism membrane organization GO:0044802 268 0.765
Human Mouse
regulation of cellular component size GO:0032535 82 0.763
Mouse
vacuole organization GO:0007033 44 0.761
single organism cell adhesion GO:0098602 179 0.760
regulation of exocytosis GO:0017157 46 0.753
regulation of cell division GO:0051302 116 0.753
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.744
regulation of cell cycle process GO:0010564 266 0.738
Human
regulation of neuron differentiation GO:0045664 70 0.737
Fly
cellular component assembly involved in morphogenesis GO:0010927 73 0.736
Fly
cellular response to abiotic stimulus GO:0071214 117 0.733
interleukin 23 production GO:0032627 5 0.732
establishment of organelle localization GO:0051656 59 0.729
epidermis morphogenesis GO:0048730 3 0.726
reproductive process GO:0022414 106 0.725
Worm Fly
regulation of dephosphorylation GO:0035303 96 0.720
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.718
protein targeting GO:0006605 187 0.717
chemotaxis GO:0006935 157 0.712
regulation of cell cell adhesion GO:0022407 57 0.709
maintenance of protein location GO:0045185 57 0.709
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.708
neural tube formation GO:0001841 3 0.707
negative regulation of protein maturation GO:1903318 142 0.707
positive regulation of protein polymerization GO:0032273 45 0.706
Mouse
regulation of proteolysis GO:0030162 293 0.701
regulation of focal adhesion assembly GO:0051893 20 0.692
multicellular organismal aging GO:0010259 3 0.692
regionalization GO:0003002 29 0.686
Fly
midbrain development GO:0030901 45 0.680
Human
defense response to bacterium GO:0042742 63 0.673
Fly
regulation of chemotaxis GO:0050920 74 0.671
negative regulation of proteolysis GO:0045861 132 0.669
wound healing GO:0042060 115 0.668
Fly
developmental process involved in reproduction GO:0003006 66 0.668
Worm Fly
positive regulation of kinase activity GO:0033674 204 0.666
Mouse Fly
neuronal stem cell division GO:0036445 1 0.661
organelle inheritance GO:0048308 2 0.651
generation of neurons GO:0048699 152 0.650
Mouse Worm Fly
cellular response to peptide hormone stimulus GO:0071375 56 0.645
Human
regulation of cell shape GO:0008360 48 0.639
Fly
cell cell junction organization GO:0045216 69 0.638
regulation of cell substrate adhesion GO:0010810 68 0.633
regulation of protein processing GO:0070613 150 0.632
regulation of protein serine threonine kinase activity GO:0071900 179 0.630
Fly
nervous system development GO:0007399 293 0.627
Human Mouse Worm Fly
positive regulation of intracellular protein transport GO:0090316 76 0.627
system process GO:0003008 349 0.626
Fly
mitotic cell cycle GO:0000278 326 0.626
cerebral cortex cell migration GO:0021795 3 0.618
Mouse
cell substrate adhesion GO:0031589 132 0.616
determination of adult lifespan GO:0008340 2 0.611
substantia nigra development GO:0021762 45 0.610
Human
positive regulation of cell cycle GO:0045787 140 0.601
Human
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.600
neuron differentiation GO:0030182 138 0.596
Mouse Worm Fly
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.595
cell maturation GO:0048469 11 0.593
Fly
regulation of filopodium assembly GO:0051489 13 0.592
Human Fly
response to peptide GO:1901652 65 0.587
Human
protein localization to plasma membrane GO:0072659 93 0.586
Human Mouse
cell morphogenesis GO:0000902 296 0.585
regulation of protein complex assembly GO:0043254 147 0.585
Human Mouse
regulation of cellular response to stress GO:0080135 244 0.574
defense response GO:0006952 315 0.574
Fly
myoblast fusion GO:0007520 1 0.569
Fly
respiratory burst GO:0045730 12 0.558
maintenance of protein location in cell GO:0032507 56 0.558
Human
protein ubiquitination GO:0016567 314 0.551
mitotic nuclear division GO:0007067 119 0.548
sensory perception GO:0007600 103 0.547
Fly
amine metabolic process GO:0009308 44 0.543
positive regulation of phosphorylation GO:0042327 394 0.540
gastrulation GO:0007369 51 0.537
Fly
focal adhesion assembly GO:0048041 30 0.530
regulation of phosphatase activity GO:0010921 81 0.525
synaptic transmission GO:0007268 61 0.523
Fly
cellular response to organonitrogen compound GO:0071417 124 0.523
Human
positive regulation of amine transport GO:0051954 2 0.516
nuclear division GO:0000280 128 0.514
intracellular receptor signaling pathway GO:0030522 104 0.514
stem cell division GO:0017145 2 0.509
cell projection morphogenesis GO:0048858 129 0.507
Mouse Worm Fly
multicellular organismal reproductive process GO:0048609 40 0.507
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.498
Fly
canonical wnt signaling pathway GO:0060070 116 0.497
epithelial tube morphogenesis GO:0060562 38 0.497
hematopoietic or lymphoid organ development GO:0048534 186 0.497
Fly
positive regulation of neutrophil migration GO:1902624 7 0.497
neuron projection morphogenesis GO:0048812 50 0.497
Mouse Worm Fly
sensory perception of mechanical stimulus GO:0050954 37 0.497
Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.492
somatic stem cell division GO:0048103 1 0.489
cytokinetic process GO:0032506 12 0.489
neurological system process GO:0050877 163 0.485
Fly
regulation of actin filament length GO:0030832 56 0.481
Mouse
regulation of protein maturation GO:1903317 150 0.475
peripheral nervous system development GO:0007422 2 0.474
Fly
single organism reproductive process GO:0044702 98 0.473
Worm Fly
negative regulation of phosphatase activity GO:0010923 61 0.468
lipid localization GO:0010876 106 0.467
Fly
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.467
neural nucleus development GO:0048857 47 0.464
Human
engulfment of apoptotic cell GO:0043652 2 0.463
Mouse Worm
protein targeting to nucleus GO:0044744 104 0.461
regulation of cellular ketone metabolic process GO:0010565 50 0.456
microtubule based movement GO:0007018 32 0.453
cellular response to peptide GO:1901653 59 0.451
Human
substrate adhesion dependent cell spreading GO:0034446 41 0.449
neuron fate commitment GO:0048663 2 0.445
positive regulation of fibroblast migration GO:0010763 3 0.444
cellular amino acid metabolic process GO:0006520 116 0.440
neuron projection development GO:0031175 106 0.431
Mouse Worm Fly
ectodermal placode development GO:0071696 1 0.426
positive regulation of actin nucleation GO:0051127 6 0.423
keratinocyte differentiation GO:0030216 36 0.420
muscle cell differentiation GO:0042692 63 0.418
Fly
cardiac conduction system development GO:0003161 2 0.416
morphogenesis of a branching structure GO:0001763 21 0.411
secretion by cell GO:0032940 226 0.408
maintenance of location in cell GO:0051651 62 0.406
Human
regulation of protein transport GO:0051223 213 0.404
asymmetric stem cell division GO:0098722 1 0.395
muscle organ development GO:0007517 56 0.385
Fly
negative regulation of hydrolase activity GO:0051346 182 0.385
regulation of glucose transport GO:0010827 23 0.383
Human
leukocyte chemotaxis GO:0030595 76 0.383
mitochondrion organization GO:0007005 156 0.380
determination of left right symmetry GO:0007368 11 0.375
Fly
positive regulation of apoptotic process GO:0043065 246 0.370
aging GO:0007568 66 0.368
positive regulation of locomotion GO:0040017 186 0.366
positive regulation of actin filament polymerization GO:0030838 38 0.364
Mouse
response to wounding GO:0009611 168 0.364
Worm Fly
regulation of hair follicle cell proliferation GO:0071336 1 0.363
positive regulation of cell cycle process GO:0090068 106 0.361
Human
positive regulation of protein transport GO:0051222 135 0.356
neurogenesis GO:0022008 169 0.354
Mouse Worm Fly
digestive system development GO:0055123 75 0.354
Fly
cytoskeleton dependent cytokinesis GO:0061640 22 0.349
protein polymerization GO:0051258 71 0.347
Mouse
regulation of microtubule based process GO:0032886 74 0.347
Human
post embryonic development GO:0009791 2 0.347
Worm Fly
cytoskeleton dependent intracellular transport GO:0030705 21 0.345
positive regulation of wound healing GO:0090303 20 0.340
Fly
adherens junction organization GO:0034332 36 0.340
protein localization to nucleus GO:0034504 136 0.339
response to hormone GO:0009725 175 0.339
Human
regulation of peptidyl serine phosphorylation GO:0033135 50 0.338
cdc42 protein signal transduction GO:0032488 4 0.338
establishment of planar polarity GO:0001736 3 0.336
Mouse Fly
positive regulation of macrophage differentiation GO:0045651 7 0.335
regulation of kinase activity GO:0043549 314 0.333
Mouse Fly
positive regulation of mapk cascade GO:0043410 190 0.332
cellular divalent inorganic cation homeostasis GO:0072503 128 0.327
extrinsic apoptotic signaling pathway GO:0097191 119 0.326
negative regulation of lamellipodium organization GO:1902744 4 0.326
Fly
response to peptide hormone GO:0043434 61 0.325
Human
digestive tract development GO:0048565 75 0.324
Fly
carbohydrate transport GO:0008643 37 0.324
Human
positive regulation of cell migration GO:0030335 172 0.323
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.322
morphogenesis of embryonic epithelium GO:0016331 4 0.320
Fly
organelle fusion GO:0048284 36 0.320
regulation of apoptotic signaling pathway GO:2001233 175 0.319
ectodermal placode formation GO:0060788 1 0.316
negative regulation of dephosphorylation GO:0035305 63 0.311
spermatid development GO:0007286 4 0.307
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.302
forebrain generation of neurons GO:0021872 3 0.296
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.289
heart development GO:0007507 95 0.284
positive regulation of arp2 3 complex mediated actin nucleation GO:2000601 5 0.277
neutrophil migration GO:1990266 25 0.275
regulation of synapse structural plasticity GO:0051823 2 0.271
positive regulation of cell motility GO:2000147 177 0.267
positive regulation of exocytosis GO:0045921 35 0.264
nucleocytoplasmic transport GO:0006913 176 0.262
negative regulation of dna metabolic process GO:0051053 57 0.259
regulation of mitosis GO:0007088 63 0.256
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.255
i kappab kinase nf kappab signaling GO:0007249 166 0.253
regulation of vacuole organization GO:0044088 8 0.253
ribonucleoprotein complex subunit organization GO:0071826 81 0.250
cellular response to hormone stimulus GO:0032870 125 0.250
Human
nuclear transport GO:0051169 179 0.248
regulation of intracellular estrogen receptor signaling pathway GO:0033146 13 0.246
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.246
Human
single organism membrane fusion GO:0044801 37 0.244
glucose transport GO:0015758 30 0.239
Human
positive regulation of cell junction assembly GO:1901890 11 0.238
glucose import GO:0046323 24 0.238
Human
regulation of ion transport GO:0043269 189 0.236
cardiovascular system development GO:0072358 262 0.235
regulation of intracellular transport GO:0032386 195 0.232
positive regulation of neuron apoptotic process GO:0043525 8 0.231
erythrocyte homeostasis GO:0034101 31 0.231
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.231
regulation of anatomical structure size GO:0090066 101 0.230
Mouse
hexose transport GO:0008645 30 0.230
Human
monosaccharide transport GO:0015749 32 0.229
Human
directional locomotion GO:0033058 1 0.228
regulation of locomotion GO:0040012 329 0.227
embryo development GO:0009790 123 0.225
Mouse Worm Fly
regulation of establishment of protein localization GO:0070201 242 0.225
Human
regulation of protein stability GO:0031647 87 0.222
regulation of neuron apoptotic process GO:0043523 35 0.220
regulation of secretion by cell GO:1903530 177 0.220
positive regulation of filopodium assembly GO:0051491 7 0.217
Human Fly
cell growth GO:0016049 160 0.217
Worm Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.213
Human
neuron development GO:0048666 113 0.209
Mouse Worm Fly
positive regulation of neurotransmitter transport GO:0051590 1 0.208
syncytium formation by plasma membrane fusion GO:0000768 2 0.207
Fly
positive regulation of protein localization to plasma membrane GO:1903078 20 0.206
Human
actin cytoskeleton reorganization GO:0031532 37 0.205
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.204
leukocyte cell cell adhesion GO:0007159 37 0.203
Human
regulation of cytokinesis GO:0032465 45 0.202
Human
regulation of macrophage differentiation GO:0045649 9 0.201
cellular response to radiation GO:0071478 65 0.200
execution phase of apoptosis GO:0097194 32 0.200
positive regulation of focal adhesion assembly GO:0051894 11 0.198
regulation of cell junction assembly GO:1901888 29 0.195
positive regulation of protein localization to nucleus GO:1900182 48 0.193
negative regulation of protein complex assembly GO:0031333 43 0.192
Human
response to molecule of bacterial origin GO:0002237 82 0.190
regulation of cellular component movement GO:0051270 334 0.190
regulation of actin polymerization or depolymerization GO:0008064 56 0.189
Mouse
fibroblast migration GO:0010761 7 0.188
gonad development GO:0008406 34 0.185
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.184
endocytosis GO:0006897 159 0.183
Mouse Worm Fly

RAC1 disease predictions

Disease DO term ID Size Probability Func Analog Org