Homo sapiens

67 known processes

VCL

vinculin

(Aliases: MVCL,CMD1W,CMH15)

VCL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament organization GO:0007015 128 0.954
actin cytoskeleton organization GO:0030036 207 0.919
actin filament based process GO:0030029 224 0.903
muscle structure development GO:0061061 98 0.860
cellular component morphogenesis GO:0032989 314 0.853
Mouse Fly
integrin mediated signaling pathway GO:0007229 32 0.809
response to growth factor GO:0070848 205 0.807
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.785
negative regulation of hippo signaling GO:0035331 6 0.720
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.702
post embryonic development GO:0009791 2 0.685
muscle cell development GO:0055001 29 0.665
positive regulation of cellular component organization GO:0051130 376 0.647
vesicle mediated transport GO:0016192 371 0.647
Fly
cell adhesion GO:0007155 325 0.642
regulation of cellular component biogenesis GO:0044087 281 0.613
regulation of body fluid levels GO:0050878 99 0.598
cellular response to growth factor stimulus GO:0071363 197 0.584
cell junction organization GO:0034330 79 0.567
maintenance of location in cell GO:0051651 62 0.562
Worm
cellular macromolecular complex assembly GO:0034622 324 0.561
single organism cellular localization GO:1902580 332 0.559
striated muscle cell differentiation GO:0051146 43 0.558
cell morphogenesis GO:0000902 296 0.539
Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.482
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.472
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.458
regulation of cell morphogenesis GO:0022604 153 0.452
hippo signaling GO:0035329 20 0.437
cell substrate adhesion GO:0031589 132 0.432
actomyosin structure organization GO:0031032 59 0.422
single organismal cell cell adhesion GO:0016337 148 0.419
organelle assembly GO:0070925 176 0.412
response to transforming growth factor beta GO:0071559 94 0.409
nucleoside triphosphate metabolic process GO:0009141 422 0.399
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.398
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.396
protein catabolic process GO:0030163 325 0.375
Worm
protein localization to membrane GO:0072657 160 0.374
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.369
small gtpase mediated signal transduction GO:0007264 78 0.362
Human
wound healing GO:0042060 115 0.360
cellular protein complex assembly GO:0043623 188 0.340
cation transmembrane transport GO:0098655 238 0.339
biological adhesion GO:0022610 331 0.332
blood coagulation GO:0007596 76 0.331
regulation of cell motility GO:2000145 299 0.331
Mouse
cell projection organization GO:0030030 252 0.322
Mouse Fly
regulation of cell adhesion GO:0030155 166 0.318
cell development GO:0048468 328 0.314
Mouse Fly
cell matrix adhesion GO:0007160 85 0.309
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.309
negative regulation of cell motility GO:2000146 104 0.308
regulation of actin cytoskeleton organization GO:0032956 116 0.304
substrate adhesion dependent cell spreading GO:0034446 41 0.299
negative regulation of locomotion GO:0040013 118 0.296
focal adhesion assembly GO:0048041 30 0.296
anatomical structure formation involved in morphogenesis GO:0048646 284 0.292
neuron differentiation GO:0030182 138 0.289
Mouse Fly
ameboidal type cell migration GO:0001667 135 0.281
positive regulation of cell migration GO:0030335 172 0.281
cell cell junction organization GO:0045216 69 0.281
positive regulation of actin filament bundle assembly GO:0032233 25 0.280
wnt signaling pathway GO:0016055 156 0.276
inorganic ion transmembrane transport GO:0098660 231 0.273
establishment of cell polarity GO:0030010 22 0.270
cellular response to endogenous stimulus GO:0071495 336 0.264
Human
cell migration involved in gastrulation GO:0042074 1 0.260
regulation of cytoskeleton organization GO:0051493 177 0.259
tissue morphogenesis GO:0048729 96 0.257
cellular component assembly involved in morphogenesis GO:0010927 73 0.256
positive regulation of cell motility GO:2000147 177 0.254
ras protein signal transduction GO:0007265 73 0.253
Human
regulation of actin filament length GO:0030832 56 0.248
cell activation GO:0001775 213 0.245
regulation of metal ion transport GO:0010959 120 0.244
nucleoside phosphate catabolic process GO:1901292 412 0.244
plasma membrane organization GO:0007009 115 0.231
vasculature development GO:0001944 181 0.231
platelet activation GO:0030168 44 0.229
striated muscle cell development GO:0055002 27 0.229
nucleoside catabolic process GO:0009164 408 0.225
cellular response to organonitrogen compound GO:0071417 124 0.218
Human
response to abiotic stimulus GO:0009628 336 0.218
ribonucleoside catabolic process GO:0042454 406 0.216
mitotic cell cycle GO:0000278 326 0.213
cellular amine metabolic process GO:0044106 41 0.210
response to wounding GO:0009611 168 0.206
determination of adult lifespan GO:0008340 2 0.203
cellular response to oxygen containing compound GO:1901701 276 0.202
Human
single organism membrane organization GO:0044802 268 0.199
maintenance of protein location in cell GO:0032507 56 0.197
Worm
regulation of actin filament based process GO:0032970 141 0.193
positive regulation of organelle organization GO:0010638 195 0.190
leukocyte cell cell adhesion GO:0007159 37 0.186
negative regulation of cellular component movement GO:0051271 106 0.185
cell junction assembly GO:0034329 67 0.184
mitotic cell cycle process GO:1903047 286 0.183
single organism cell adhesion GO:0098602 179 0.182
positive regulation of cytoskeleton organization GO:0051495 83 0.182
purine ribonucleoside catabolic process GO:0046130 398 0.181
enzyme linked receptor protein signaling pathway GO:0007167 303 0.180
nerve development GO:0021675 4 0.177
myosin filament assembly GO:0031034 2 0.175
purine nucleotide catabolic process GO:0006195 405 0.171
nucleoside triphosphate catabolic process GO:0009143 394 0.169
embryonic forelimb morphogenesis GO:0035115 4 0.167
cell morphogenesis involved in differentiation GO:0000904 144 0.166
Mouse
female gamete generation GO:0007292 2 0.165
apoptotic signaling pathway GO:0097190 268 0.164
multicellular organismal aging GO:0010259 3 0.163
ribonucleoside triphosphate metabolic process GO:0009199 412 0.162
epithelial cell migration GO:0010631 119 0.162
regulation of actin filament polymerization GO:0030833 50 0.162
cell substrate adherens junction assembly GO:0007045 30 0.161
purine nucleoside triphosphate catabolic process GO:0009146 392 0.161
actin filament bundle organization GO:0061572 54 0.160
stress fiber assembly GO:0043149 40 0.154
negative regulation of programmed cell death GO:0043069 321 0.153
ribonucleotide catabolic process GO:0009261 405 0.152
regulation of cellular ketone metabolic process GO:0010565 50 0.152
regulation of cellular response to growth factor stimulus GO:0090287 76 0.149
elastic fiber assembly GO:0048251 3 0.147
muscle organ development GO:0007517 56 0.146
striated muscle myosin thick filament assembly GO:0071688 2 0.145
sensory perception GO:0007600 103 0.145
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.144
regulation of cellular amino acid metabolic process GO:0006521 6 0.143
endomembrane system organization GO:0010256 196 0.142
regulation of cell migration GO:0030334 289 0.141
Mouse
tube morphogenesis GO:0035239 95 0.138
gtp metabolic process GO:0046039 239 0.133
embryonic viscerocranium morphogenesis GO:0048703 1 0.132
ubiquitin dependent protein catabolic process GO:0006511 206 0.130
blood vessel development GO:0001568 172 0.130
divalent metal ion transport GO:0070838 152 0.129
positive regulation of transport GO:0051050 336 0.129
neuron development GO:0048666 113 0.128
Mouse Fly
engulfment of apoptotic cell GO:0043652 2 0.128
regulation of protein complex assembly GO:0043254 147 0.126
rho protein signal transduction GO:0007266 26 0.125
Human
glycosyl compound catabolic process GO:1901658 413 0.125
regulation of protein polymerization GO:0032271 63 0.123
cellular response to oxidative stress GO:0034599 85 0.123
circulatory system development GO:0072359 262 0.121
negative regulation of transport GO:0051051 176 0.121
positive regulation of cellular component biogenesis GO:0044089 158 0.120
i kappab kinase nf kappab signaling GO:0007249 166 0.118
regulation of vesicle mediated transport GO:0060627 130 0.117
cellular extravasation GO:0045123 21 0.117
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.117
positive regulation of phosphorylation GO:0042327 394 0.115
positive regulation of protein complex assembly GO:0031334 86 0.115
cellular protein catabolic process GO:0044257 261 0.114
cell part morphogenesis GO:0032990 137 0.114
Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.114
angiogenesis GO:0001525 147 0.113
establishment or maintenance of cell polarity GO:0007163 31 0.111
embryo development GO:0009790 123 0.111
Worm
cellular amino acid metabolic process GO:0006520 116 0.111
divalent inorganic cation transport GO:0072511 158 0.111
cell chemotaxis GO:0060326 112 0.109
nucleotide catabolic process GO:0009166 408 0.108
regulation of actin polymerization or depolymerization GO:0008064 56 0.108
muscle cell differentiation GO:0042692 63 0.107
membrane organization GO:0061024 292 0.107
positive regulation of locomotion GO:0040017 186 0.106
establishment of monopolar cell polarity GO:0061162 1 0.105
transmembrane transport GO:0055085 399 0.104
regulation of myoblast fusion GO:1901739 1 0.104
regulation of cell cycle GO:0051726 393 0.103
digestive tract development GO:0048565 75 0.103
amine metabolic process GO:0009308 44 0.101
nuclear division GO:0000280 128 0.101
regulation of cellular amine metabolic process GO:0033238 11 0.101
regulation of b cell receptor signaling pathway GO:0050855 4 0.100
regulation of purine nucleotide metabolic process GO:1900542 264 0.100
guanosine containing compound metabolic process GO:1901068 244 0.099
modification dependent protein catabolic process GO:0019941 209 0.098
nervous system development GO:0007399 293 0.098
Mouse Fly
neurogenesis GO:0022008 169 0.097
Mouse Fly
actin filament polymerization GO:0030041 45 0.097
positive regulation of actin filament polymerization GO:0030838 38 0.096
oocyte differentiation GO:0009994 2 0.096
actin filament bundle assembly GO:0051017 54 0.096
actin polymerization or depolymerization GO:0008154 56 0.096
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.096
cation transport GO:0006812 331 0.096
anterior posterior axis specification GO:0009948 2 0.096
purine containing compound catabolic process GO:0072523 411 0.095
cardiac muscle tissue development GO:0048738 39 0.095
response to organonitrogen compound GO:0010243 156 0.095
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.094
negative regulation of cell death GO:0060548 345 0.093
metal ion transport GO:0030001 272 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.088
oogenesis GO:0048477 2 0.088
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.088
regulation of protein localization GO:0032880 296 0.087
hindbrain development GO:0030902 3 0.087
purine nucleoside triphosphate metabolic process GO:0009144 412 0.085
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.084
striated muscle tissue development GO:0014706 59 0.084
purine ribonucleotide catabolic process GO:0009154 404 0.083
adherens junction organization GO:0034332 36 0.083
protein polymerization GO:0051258 71 0.083
regulation of cell shape GO:0008360 48 0.083
salivary gland morphogenesis GO:0007435 4 0.082
lens morphogenesis in camera type eye GO:0002089 2 0.081
positive regulation of cellular component movement GO:0051272 181 0.079
blood vessel morphogenesis GO:0048514 162 0.078
regulation of transferase activity GO:0051338 355 0.078
morphogenesis of a polarized epithelium GO:0001738 3 0.078
homotypic cell cell adhesion GO:0034109 47 0.078
negative regulation of b cell receptor signaling pathway GO:0050859 2 0.078
purine nucleoside catabolic process GO:0006152 398 0.077
positive regulation of cellular catabolic process GO:0031331 284 0.077
protein import GO:0017038 130 0.077
pharynx development GO:0060465 1 0.076
regulation of phagocytosis engulfment GO:0060099 2 0.076
establishment of organelle localization GO:0051656 59 0.075
positive regulation of cell adhesion GO:0045785 84 0.075
generation of neurons GO:0048699 152 0.075
Mouse Fly
negative regulation of apoptotic process GO:0043066 316 0.075
negative regulation of cellular protein metabolic process GO:0032269 353 0.074
negative regulation of protein transport GO:0051224 75 0.074
maintenance of protein location GO:0045185 57 0.073
Worm
tissue migration GO:0090130 119 0.073
epithelium development GO:0060429 227 0.073
protein import into nucleus GO:0006606 104 0.073
purine ribonucleoside metabolic process GO:0046128 437 0.072
taxis GO:0042330 157 0.071
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.070
positive regulation of cell substrate adhesion GO:0010811 37 0.070
endoderm development GO:0007492 33 0.070
regulation of map kinase activity GO:0043405 108 0.070
response to nitrogen compound GO:1901698 184 0.069
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.068
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.068
hemostasis GO:0007599 76 0.067
odontogenesis GO:0042476 25 0.067
regulation of nucleotide metabolic process GO:0006140 269 0.067
establishment of protein localization to plasma membrane GO:0090002 68 0.065
microtubule cytoskeleton organization GO:0000226 176 0.064
positive regulation of catabolic process GO:0009896 310 0.064
nucleocytoplasmic transport GO:0006913 176 0.064
regulation of wnt signaling pathway GO:0030111 123 0.064
muscle tissue development GO:0060537 62 0.062
gtp catabolic process GO:0006184 237 0.062
organelle fission GO:0048285 149 0.061
response to mercury ion GO:0046689 4 0.061
endocytosis GO:0006897 159 0.061
Fly
myoblast fusion GO:0007520 1 0.061
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.061
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.061
oocyte development GO:0048599 1 0.060
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.060
endodermal cell differentiation GO:0035987 31 0.060
myofibril assembly GO:0030239 10 0.060
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.059
cellular ketone metabolic process GO:0042180 80 0.059
regulation of protein localization to plasma membrane GO:1903076 40 0.059
negative regulation of cell adhesion GO:0007162 64 0.059
positive regulation of protein kinase activity GO:0045860 190 0.058
negative regulation of intracellular signal transduction GO:1902532 183 0.058
protein localization to organelle GO:0033365 280 0.058
mitotic cell cycle phase transition GO:0044772 162 0.058
establishment of protein localization to organelle GO:0072594 172 0.057
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.057
organ morphogenesis GO:0009887 147 0.056
regulation of rho gtpase activity GO:0032319 66 0.056
cell adhesion mediated by integrin GO:0033627 27 0.056
blood vessel endothelial cell migration GO:0043534 42 0.056
negative regulation of developmental process GO:0051093 247 0.055
regulation of cellular component movement GO:0051270 334 0.055
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.055
ion transmembrane transport GO:0034220 338 0.054
inorganic cation transmembrane transport GO:0098662 194 0.054
response to decreased oxygen levels GO:0036293 96 0.054
single organism nuclear import GO:1902593 104 0.054
cellular macromolecule catabolic process GO:0044265 380 0.054
anterior posterior axis specification embryo GO:0008595 2 0.054
protein homooligomerization GO:0051260 100 0.052
cellular homeostasis GO:0019725 196 0.052
epithelial cell differentiation GO:0030855 141 0.052
mesenchymal cell development GO:0014031 50 0.051
protein oligomerization GO:0051259 173 0.051
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.051
regulation of cytoplasmic transport GO:1903649 149 0.051
actin filament based movement GO:0030048 17 0.051
embryo development ending in birth or egg hatching GO:0009792 34 0.050
Worm
regulation of actin filament bundle assembly GO:0032231 36 0.050
peptidyl tyrosine modification GO:0018212 170 0.050
skeletal muscle organ development GO:0060538 26 0.049
cytoplasmic transport GO:0016482 379 0.049
cellular response to mercury ion GO:0071288 2 0.048
negative regulation of cell differentiation GO:0045596 171 0.048
establishment of protein localization to membrane GO:0090150 121 0.048
neurological system process GO:0050877 163 0.048
axonogenesis GO:0007409 31 0.048
Mouse
cerebral cortex radially oriented cell migration GO:0021799 1 0.047
cellular response to oxygen levels GO:0071453 55 0.047
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.047
behavior GO:0007610 112 0.047
tube development GO:0035295 125 0.046
organophosphate catabolic process GO:0046434 430 0.045
protein localization to plasma membrane GO:0072659 93 0.045
transcription factor import into nucleus GO:0042991 40 0.045
autophagy GO:0006914 88 0.045
negative regulation of apoptotic signaling pathway GO:2001234 97 0.045
positive regulation of hydrolase activity GO:0051345 331 0.044
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.044
cardiovascular system development GO:0072358 262 0.043
regulation of epithelial cell migration GO:0010632 93 0.042
establishment or maintenance of monopolar cell polarity GO:0061339 1 0.042
peptidyl tyrosine phosphorylation GO:0018108 170 0.042
metal ion homeostasis GO:0055065 169 0.042
protein targeting to nucleus GO:0044744 104 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.042
establishment of apical basal cell polarity GO:0035089 1 0.042
regulation of protein import into nucleus GO:0042306 78 0.042
tripartite regional subdivision GO:0007351 2 0.041
cranial nerve development GO:0021545 4 0.041
maintenance of location GO:0051235 112 0.041
Worm
regulation of protein kinase activity GO:0045859 289 0.041
regulation of protein binding GO:0043393 66 0.041
regulation of membrane potential GO:0042391 95 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
regulation of cell matrix adhesion GO:0001952 42 0.040
regulation of transporter activity GO:0032409 82 0.040
regulation of cell projection organization GO:0031344 107 0.040
regulation of cell development GO:0060284 161 0.040
regulation of intracellular transport GO:0032386 195 0.040
meiotic chromosome segregation GO:0045132 4 0.039
positive regulation of epithelial cell migration GO:0010634 55 0.039
cellular response to reactive oxygen species GO:0034614 50 0.039
adherens junction assembly GO:0034333 34 0.039
endothelial cell migration GO:0043542 86 0.039
regulation of ion transmembrane transport GO:0034765 132 0.038
positive regulation of gtp catabolic process GO:0033126 166 0.038
regulation of cellular response to stress GO:0080135 244 0.038
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.038
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
proteasomal protein catabolic process GO:0010498 176 0.038
nuclear transport GO:0051169 179 0.038
multicellular organismal signaling GO:0035637 34 0.038
embryonic morphogenesis GO:0048598 85 0.037
negative regulation of cytoskeleton organization GO:0051494 45 0.037
myosin filament organization GO:0031033 2 0.037
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.037
embryonic epithelial tube formation GO:0001838 4 0.037
response to oxygen levels GO:0070482 100 0.037
response to bacterium GO:0009617 144 0.036
regulation of endocytosis GO:0030100 72 0.036
response to external biotic stimulus GO:0043207 261 0.036
positive regulation of gtpase activity GO:0043547 166 0.036
regulation of cell cell adhesion GO:0022407 57 0.036
regulation of epithelial to mesenchymal transition GO:0010717 37 0.036
positive regulation of programmed cell death GO:0043068 249 0.036
calcium ion transmembrane transport GO:0070588 76 0.035
morphogenesis of embryonic epithelium GO:0016331 4 0.035
single organism reproductive process GO:0044702 98 0.035
guanosine containing compound catabolic process GO:1901069 239 0.035
cranial nerve morphogenesis GO:0021602 1 0.035
post embryonic organ development GO:0048569 1 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.035
protein localization to nucleus GO:0034504 136 0.035
epithelium migration GO:0090132 119 0.034
chordate embryonic development GO:0043009 34 0.034
morphogenesis of an epithelium GO:0002009 60 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
lipid transport GO:0006869 90 0.034
negative regulation of cell migration GO:0030336 102 0.034
growth GO:0040007 202 0.034
Mouse
positive regulation of apoptotic process GO:0043065 246 0.033
regulation of protein transport GO:0051223 213 0.033
regulation of neuron projection development GO:0010975 57 0.033
system process GO:0003008 349 0.033
cell cycle phase transition GO:0044770 173 0.033
receptor mediated endocytosis GO:0006898 84 0.033
negative regulation of protein modification process GO:0031400 200 0.033
regulation of stress fiber assembly GO:0051492 32 0.033
response to hypoxia GO:0001666 96 0.033
positive regulation of neutrophil apoptotic process GO:0033031 1 0.033
negative regulation of intracellular transport GO:0032387 60 0.032
cellular response to hypoxia GO:0071456 51 0.032
positive regulation of mapk cascade GO:0043410 190 0.032
regulation of wound healing GO:0061041 56 0.032
response to oxygen containing compound GO:1901700 369 0.032
Human
chemotaxis GO:0006935 157 0.032
regulation of cellular component size GO:0032535 82 0.032
regulation of purine nucleotide catabolic process GO:0033121 205 0.032
positive regulation of endocytosis GO:0045807 42 0.032
regulation of striated muscle cell differentiation GO:0051153 25 0.032
regulation of nucleoside metabolic process GO:0009118 209 0.032
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.032
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.032
mating GO:0007618 1 0.032
ectoderm development GO:0007398 3 0.032
nucleus localization GO:0051647 1 0.032
cytokinesis GO:0000910 96 0.032
neural tube formation GO:0001841 3 0.032
cell division GO:0051301 168 0.031
regulation of gene silencing by mirna GO:0060964 6 0.031
actin nucleation GO:0045010 21 0.031
regulation of nucleocytoplasmic transport GO:0046822 98 0.031
negative regulation of organelle organization GO:0010639 126 0.031
muscle system process GO:0003012 81 0.031
regulation of mapk cascade GO:0043408 262 0.031
monovalent inorganic cation transport GO:0015672 128 0.031
positive regulation of cell death GO:0010942 263 0.031
cell projection morphogenesis GO:0048858 129 0.031
Mouse Fly
cardiac muscle tissue morphogenesis GO:0055008 18 0.030
cilium morphogenesis GO:0060271 75 0.030
positive regulation of substrate adhesion dependent cell spreading GO:1900026 15 0.030
actin mediated cell contraction GO:0070252 12 0.030
negative regulation of protein maturation GO:1903318 142 0.030
positive regulation of transferase activity GO:0051347 227 0.030
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.030
metencephalon development GO:0022037 2 0.029
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.029
skin development GO:0043588 76 0.029
positive regulation of protein import into nucleus GO:0042307 46 0.029
lens development in camera type eye GO:0002088 2 0.029
regulation of apoptotic signaling pathway GO:2001233 175 0.028
positive regulation of axon extension GO:0045773 4 0.028
positive regulation of intracellular protein transport GO:0090316 76 0.028
regulation of protein targeting GO:1903533 91 0.028
intracellular protein transport GO:0006886 270 0.028
extrinsic apoptotic signaling pathway GO:0097191 119 0.028
positive regulation of phagocytosis engulfment GO:0060100 1 0.028
optic nerve development GO:0021554 2 0.028
regulation of lipoprotein metabolic process GO:0050746 7 0.027
regulation of rho protein signal transduction GO:0035023 79 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
cell projection assembly GO:0030031 126 0.027
Mouse
response to oxidative stress GO:0006979 121 0.027
nucleoside monophosphate catabolic process GO:0009125 159 0.027
cytoplasmic mrna processing body assembly GO:0033962 10 0.027
antigen receptor mediated signaling pathway GO:0050851 38 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
glial cell migration GO:0008347 4 0.027
regulation of actin filament depolymerization GO:0030834 10 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
regulation of transcription factor import into nucleus GO:0042990 39 0.026
sister chromatid segregation GO:0000819 54 0.026
regulation of intracellular protein transport GO:0033157 123 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
epithelial cell development GO:0002064 34 0.026
morphogenesis of an epithelial sheet GO:0002011 12 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
positive regulation of kinase activity GO:0033674 204 0.025
heterotypic cell cell adhesion GO:0034113 28 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
cellular response to decreased oxygen levels GO:0036294 51 0.025
adult locomotory behavior GO:0008344 1 0.025
neuron projection regeneration GO:0031102 1 0.025
establishment of nucleus localization GO:0040023 1 0.025
platelet aggregation GO:0070527 32 0.025
regulation of establishment of protein localization GO:0070201 242 0.024
regulation of protein localization to nucleus GO:1900180 85 0.024
mapk cascade GO:0000165 288 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
cell substrate junction assembly GO:0007044 35 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
cellular response to nitrogen compound GO:1901699 144 0.024
Human
positive regulation of endothelial cell migration GO:0010595 39 0.024
blastoderm segmentation GO:0007350 2 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
sensory perception of sound GO:0007605 37 0.023
visual learning GO:0008542 1 0.023
regulation of neurogenesis GO:0050767 82 0.023
cardiac muscle contraction GO:0060048 34 0.023
cellular response to prostaglandin e stimulus GO:0071380 3 0.023
actin filament capping GO:0051693 4 0.023
regulation of cell substrate adhesion GO:0010810 68 0.023
locomotory behavior GO:0007626 1 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
neuron projection development GO:0031175 106 0.023
Mouse Fly
negative regulation of cellular component organization GO:0051129 235 0.022

VCL disease predictions

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 114 0.045
musculoskeletal system disease DOID:17 223 0.045
muscle tissue disease DOID:66 113 0.044
disease of cellular proliferation DOID:14566 174 0.040
auditory system disease DOID:2742 53 0.039
sensory system disease DOID:0050155 203 0.039
nervous system disease DOID:863 431 0.039
disease of metabolism DOID:0014667 295 0.024
myopathy DOID:423 104 0.023
heart disease DOID:114 68 0.023
cardiomyopathy DOID:0050700 50 0.023
cardiovascular system disease DOID:1287 106 0.023