Homo sapiens

0 known processes

CUL5

cullin 5

(Aliases: VACM-1,VACM1)

CUL5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.995
Mouse
modification dependent protein catabolic process GO:0019941 209 0.893
modification dependent macromolecule catabolic process GO:0043632 212 0.766
cellular macromolecule catabolic process GO:0044265 380 0.705
protein catabolic process GO:0030163 325 0.615
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.595
post embryonic development GO:0009791 2 0.552
positive regulation of catabolic process GO:0009896 310 0.515
protein ubiquitination GO:0016567 314 0.504
Mouse
positive regulation of apoptotic process GO:0043065 246 0.464
proteasomal protein catabolic process GO:0010498 176 0.423
protein neddylation GO:0045116 7 0.401
mitotic cell cycle GO:0000278 326 0.374
Worm
positive regulation of protein catabolic process GO:0045732 75 0.358
regulation of protein catabolic process GO:0042176 155 0.323
cellular protein catabolic process GO:0044257 261 0.314
cell cycle phase transition GO:0044770 173 0.312
hindbrain development GO:0030902 3 0.287
Mouse
mitotic cell cycle process GO:1903047 286 0.282
purine nucleotide catabolic process GO:0006195 405 0.268
regulation of cell cycle GO:0051726 393 0.242
Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.241
microtubule based process GO:0007017 210 0.220
ubiquitin dependent protein catabolic process GO:0006511 206 0.212
protein polyubiquitination GO:0000209 110 0.202
positive regulation of proteolysis GO:0045862 142 0.193
regulation of meiotic cell cycle GO:0051445 4 0.184
Worm
positive regulation of cell cycle GO:0045787 140 0.164
Worm
cellular response to dna damage stimulus GO:0006974 379 0.161
regulation of cellular component biogenesis GO:0044087 281 0.149
Fly
positive regulation of meiotic cell cycle GO:0051446 2 0.147
Worm
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.145
response to abiotic stimulus GO:0009628 336 0.117
Rat
response to organic cyclic compound GO:0014070 204 0.115
regulation of cellular protein catabolic process GO:1903362 96 0.114
chromosome segregation GO:0007059 114 0.114
reproductive process GO:0022414 106 0.107
Fly
positive regulation of programmed cell death GO:0043068 249 0.106
metaphase anaphase transition of cell cycle GO:0044784 21 0.105
single organism reproductive process GO:0044702 98 0.104
Fly
response to uv GO:0009411 73 0.102
mitochondrion organization GO:0007005 156 0.100
regulation of growth GO:0040008 165 0.099
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.099
morphogenesis of embryonic epithelium GO:0016331 4 0.096
protein processing GO:0016485 226 0.096
behavior GO:0007610 112 0.091
multicellular organismal catabolic process GO:0044243 12 0.088
negative regulation of mitotic cell cycle GO:0045930 102 0.087
Worm
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.086
nucleoside triphosphate metabolic process GO:0009141 422 0.085
cell development GO:0048468 328 0.084
Fly
positive regulation of cell death GO:0010942 263 0.084
regulation of proteolysis GO:0030162 293 0.082
purine nucleoside triphosphate metabolic process GO:0009144 412 0.082
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.080
ribonucleotide catabolic process GO:0009261 405 0.077
female gamete generation GO:0007292 2 0.077
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.075
cellular component morphogenesis GO:0032989 314 0.075
nucleoside phosphate catabolic process GO:1901292 412 0.074
negative regulation of cell death GO:0060548 345 0.073
maintenance of location GO:0051235 112 0.071
multicellular organismal metabolic process GO:0044236 34 0.070
regulation of cell cycle process GO:0010564 266 0.069
regulation of mitotic cell cycle GO:0007346 189 0.069
Worm
multicellular organismal aging GO:0010259 3 0.068
Worm
oocyte development GO:0048599 1 0.067
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.066
response to light stimulus GO:0009416 87 0.064
negative regulation of cellular protein metabolic process GO:0032269 353 0.063
organelle localization GO:0051640 84 0.063
tripartite regional subdivision GO:0007351 2 0.061
purine nucleoside triphosphate catabolic process GO:0009146 392 0.060
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.059
response to ionizing radiation GO:0010212 65 0.057
reproductive system development GO:0061458 56 0.056
microtubule cytoskeleton organization GO:0000226 176 0.056
protein monoubiquitination GO:0006513 39 0.055
mitotic nuclear division GO:0007067 119 0.055
purine containing compound catabolic process GO:0072523 411 0.055
single organism cellular localization GO:1902580 332 0.054
developmental process involved in reproduction GO:0003006 66 0.054
Fly
cellular macromolecular complex assembly GO:0034622 324 0.054
mitotic sister chromatid separation GO:0051306 18 0.053
positive regulation of cytoplasmic transport GO:1903651 82 0.053
mitotic sister chromatid segregation GO:0000070 53 0.053
sister chromatid segregation GO:0000819 54 0.052
digestion GO:0007586 22 0.052
blastoderm segmentation GO:0007350 2 0.052
nucleotide catabolic process GO:0009166 408 0.050
response to radiation GO:0009314 151 0.050
cerebral cortex radially oriented cell migration GO:0021799 1 0.048
Mouse
positive regulation of cellular protein catabolic process GO:1903364 37 0.048
growth GO:0040007 202 0.047
Fly
embryonic epithelial tube formation GO:0001838 4 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.046
regulation of cell cycle phase transition GO:1901987 126 0.046
nucleoside catabolic process GO:0009164 408 0.045
anterior posterior axis specification GO:0009948 2 0.045
cell cycle checkpoint GO:0000075 117 0.044
reproductive structure development GO:0048608 55 0.044
apoptotic signaling pathway GO:0097190 268 0.044
regulation of ligase activity GO:0051340 29 0.043
oogenesis GO:0048477 2 0.043
Fly
determination of adult lifespan GO:0008340 2 0.042
Worm
regulation of protein transport GO:0051223 213 0.041
meiotic chromosome segregation GO:0045132 4 0.040
vesicle mediated transport GO:0016192 371 0.040
purine ribonucleoside catabolic process GO:0046130 398 0.040
embryo development GO:0009790 123 0.040
anterior posterior axis specification embryo GO:0008595 2 0.039
regulation of mitotic cell cycle phase transition GO:1901990 118 0.039
chromosome separation GO:0051304 23 0.038
multicellular organism reproduction GO:0032504 42 0.038
Fly
positive regulation of cell cycle process GO:0090068 106 0.038
dna replication GO:0006260 116 0.037
regulation of cell division GO:0051302 116 0.036
cell division GO:0051301 168 0.036
g2 dna damage checkpoint GO:0031572 26 0.036
mitotic cell cycle checkpoint GO:0007093 68 0.036
organophosphate catabolic process GO:0046434 430 0.035
negative regulation of intracellular signal transduction GO:1902532 183 0.035
reproduction GO:0000003 63 0.035
Worm Fly
cellular protein complex assembly GO:0043623 188 0.035
negative regulation of protein metabolic process GO:0051248 391 0.034
response to lipid GO:0033993 206 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
Fly
metal ion transport GO:0030001 272 0.034
cell projection organization GO:0030030 252 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
oocyte differentiation GO:0009994 2 0.033
protein import into nucleus GO:0006606 104 0.033
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
negative regulation of cell cycle GO:0045786 193 0.032
Worm
response to nitrogen compound GO:1901698 184 0.032
ribonucleoside monophosphate catabolic process GO:0009158 158 0.031
establishment of organelle localization GO:0051656 59 0.030
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.030
regulation of protein localization GO:0032880 296 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
developmental growth GO:0048589 48 0.029
Fly
regulation of dna metabolic process GO:0051052 153 0.029
small gtpase mediated signal transduction GO:0007264 78 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
negative regulation of jak stat cascade GO:0046426 4 0.028
neural tube formation GO:0001841 3 0.028
cellular response to endogenous stimulus GO:0071495 336 0.028
dna repair GO:0006281 198 0.028
double strand break repair GO:0006302 101 0.028
cyclin catabolic process GO:0008054 6 0.028
endosomal transport GO:0016197 129 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.026
regulation of protein ubiquitination GO:0031396 95 0.026
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.026
negative regulation of cell growth GO:0030308 83 0.026
response to oxygen containing compound GO:1901700 369 0.025
negative regulation of immune system process GO:0002683 136 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
cell projection morphogenesis GO:0048858 129 0.025
ion homeostasis GO:0050801 230 0.024
Rat
regulation of chromosome organization GO:0033044 103 0.024
regulation of mitotic sister chromatid separation GO:0010965 27 0.024
single organism membrane organization GO:0044802 268 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
regulation of mitosis GO:0007088 63 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.023
tube morphogenesis GO:0035239 95 0.023
cell morphogenesis GO:0000902 296 0.023
intracellular protein transport GO:0006886 270 0.023
regulation of sister chromatid segregation GO:0033045 27 0.022
cytoplasmic transport GO:0016482 379 0.022
protein targeting GO:0006605 187 0.022
organelle fission GO:0048285 149 0.022
cell part morphogenesis GO:0032990 137 0.022
regulation of chromosome segregation GO:0051983 44 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
nervous system development GO:0007399 293 0.021
Mouse Fly
regulation of transferase activity GO:0051338 355 0.021
cellular amino acid metabolic process GO:0006520 116 0.021
negative regulation of transferase activity GO:0051348 124 0.021
cofactor metabolic process GO:0051186 87 0.021
ras protein signal transduction GO:0007265 73 0.021
regulation of translation GO:0006417 89 0.021
system process GO:0003008 349 0.021
negative regulation of cell cycle phase transition GO:1901988 89 0.020
ameboidal type cell migration GO:0001667 135 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
translation GO:0006412 132 0.020
stem cell differentiation GO:0048863 93 0.020
atp catabolic process GO:0006200 157 0.020
rho protein signal transduction GO:0007266 26 0.020
sex differentiation GO:0007548 45 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
spindle organization GO:0007051 53 0.020
segmentation GO:0035282 4 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
neuromuscular junction development GO:0007528 3 0.019
Fly
nuclear transport GO:0051169 179 0.019
multicellular organismal macromolecule metabolic process GO:0044259 29 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
gonad development GO:0008406 34 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
glycosyl compound catabolic process GO:1901658 413 0.018
protein maturation GO:0051604 233 0.018
chromatin modification GO:0016568 298 0.018
multi organism reproductive process GO:0044703 54 0.018
Fly
positive regulation of organelle organization GO:0010638 195 0.018
multi organism behavior GO:0051705 14 0.018
protein k48 linked ubiquitination GO:0070936 38 0.018
regulation of mitotic sister chromatid segregation GO:0033047 27 0.018
multicellular organismal reproductive process GO:0048609 40 0.018
Fly
dna integrity checkpoint GO:0031570 71 0.018
spermatid development GO:0007286 4 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
stem cell division GO:0017145 2 0.017
viral life cycle GO:0019058 132 0.017
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
regulation of nuclear division GO:0051783 65 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.017
g2 m transition of mitotic cell cycle GO:0000086 41 0.017
spermatid differentiation GO:0048515 4 0.017
response to hormone GO:0009725 175 0.017
tissue morphogenesis GO:0048729 96 0.017
epithelial cell differentiation GO:0030855 141 0.016
positive regulation of translation GO:0045727 35 0.016
chromatin organization GO:0006325 351 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
positive regulation of transport GO:0051050 336 0.016
protein modification by small protein removal GO:0070646 92 0.016
regulation of ubiquitin protein transferase activity GO:0051438 28 0.016
negative regulation of growth GO:0045926 97 0.016
cell growth GO:0016049 160 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
response to virus GO:0009615 126 0.016
spindle elongation GO:0051231 4 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
nuclear division GO:0000280 128 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
taxis GO:0042330 157 0.015
mitotic dna integrity checkpoint GO:0044774 30 0.015
ion transmembrane transport GO:0034220 338 0.015
regulation of protein localization to nucleus GO:1900180 85 0.015
morphogenesis of an epithelium GO:0002009 60 0.015
atp metabolic process GO:0046034 176 0.014
muscle structure development GO:0061061 98 0.014
immune system development GO:0002520 195 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of kinase activity GO:0033673 106 0.014
primary neural tube formation GO:0014020 3 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
apoptotic mitochondrial changes GO:0008637 57 0.014
regulation of transcription factor import into nucleus GO:0042990 39 0.013
multi organism cellular process GO:0044764 156 0.013
development of primary sexual characteristics GO:0045137 35 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
nuclear import GO:0051170 106 0.013
multi multicellular organism process GO:0044706 18 0.013
cellular lipid metabolic process GO:0044255 303 0.013
regulation of peptidase activity GO:0052547 180 0.013
establishment of chromosome localization GO:0051303 20 0.013
nucleus localization GO:0051647 1 0.013
mitotic cell cycle phase transition GO:0044772 162 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of mitotic cell cycle GO:0045931 60 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
response to external biotic stimulus GO:0043207 261 0.012
single organism nuclear import GO:1902593 104 0.012
response to growth factor GO:0070848 205 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
urogenital system development GO:0001655 65 0.012
negative regulation of proteolysis GO:0045861 132 0.012
lipid storage GO:0019915 28 0.012
secretion by cell GO:0032940 226 0.012
nephron epithelium morphogenesis GO:0072088 15 0.012
regulation of cellular amine metabolic process GO:0033238 11 0.012
blastocyst development GO:0001824 3 0.012
cellular response to light stimulus GO:0071482 34 0.012
positive regulation of dna metabolic process GO:0051054 73 0.011
response to biotic stimulus GO:0009607 276 0.011
dna damage checkpoint GO:0000077 68 0.011
protein targeting to nucleus GO:0044744 104 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
organelle assembly GO:0070925 176 0.011
endocytosis GO:0006897 159 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
response to steroid hormone GO:0048545 80 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
aging GO:0007568 66 0.011
Worm
cellular response to radiation GO:0071478 65 0.011
positive regulation of hydrolase activity GO:0051345 331 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
chemical homeostasis GO:0048878 306 0.010
Rat
response to gamma radiation GO:0010332 14 0.010
protein localization to organelle GO:0033365 280 0.010
positive regulation of cell cycle phase transition GO:1901989 22 0.010
rna interference GO:0016246 4 0.010
embryo development ending in birth or egg hatching GO:0009792 34 0.010
regulation of protein complex assembly GO:0043254 147 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
maintenance of location in cell GO:0051651 62 0.010
regulation of homeostatic process GO:0032844 121 0.010

CUL5 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.012