Homo sapiens

173 known processes

VCP

valosin containing protein

(Aliases: IBMPFD,MGC131997,TERA,p97,MGC148092,MGC8560)

VCP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
er associated ubiquitin dependent protein catabolic process GO:0030433 31 1.000
modification dependent protein catabolic process GO:0019941 209 1.000
modification dependent macromolecule catabolic process GO:0043632 212 1.000
cellular response to misfolded protein GO:0071218 2 1.000
Yeast Worm
response to topologically incorrect protein GO:0035966 29 1.000
Yeast Worm
ubiquitin dependent protein catabolic process GO:0006511 206 1.000
er associated misfolded protein catabolic process GO:0071712 1 1.000
Yeast Worm
cellular protein catabolic process GO:0044257 261 1.000
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 1.000
cellular macromolecule catabolic process GO:0044265 380 1.000
protein catabolic process GO:0030163 325 1.000
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.999
proteasomal protein catabolic process GO:0010498 176 0.999
response to endoplasmic reticulum stress GO:0034976 49 0.998
Worm
retrograde protein transport er to cytosol GO:0030970 5 0.998
cellular response to topologically incorrect protein GO:0035967 19 0.994
Yeast Worm
single organism carbohydrate metabolic process GO:0044723 193 0.992
response to unfolded protein GO:0006986 24 0.992
Worm
regulation of protein ubiquitination GO:0031396 95 0.985
Yeast Zebrafish
protein modification by small protein conjugation GO:0032446 342 0.980
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.974
regulation of proteasomal protein catabolic process GO:0061136 87 0.971
single organism membrane organization GO:0044802 268 0.963
Yeast
endoplasmic reticulum unfolded protein response GO:0030968 16 0.959
Worm
er nucleus signaling pathway GO:0006984 23 0.941
Worm
protein oligomerization GO:0051259 173 0.909
Rat
determination of adult lifespan GO:0008340 2 0.904
carbohydrate metabolic process GO:0005975 207 0.879
mitotic cell cycle GO:0000278 326 0.877
Yeast
protein ubiquitination GO:0016567 314 0.861
ncrna catabolic process GO:0034661 14 0.846
Yeast
regulation of protein localization GO:0032880 296 0.842
Yeast
mitotic cell cycle process GO:1903047 286 0.829
Yeast
multicellular organismal aging GO:0010259 3 0.824
microtubule cytoskeleton organization GO:0000226 176 0.797
Yeast
organelle fission GO:0048285 149 0.787
Yeast Worm
nuclear envelope reassembly GO:0031468 3 0.763
cellular response to unfolded protein GO:0034620 16 0.753
Worm
response to misfolded protein GO:0051788 5 0.753
Yeast Worm
cellular carbohydrate metabolic process GO:0044262 84 0.750
intracellular protein transport GO:0006886 270 0.743
single organism membrane fusion GO:0044801 37 0.691
Yeast
regulation of protein localization to nucleus GO:1900180 85 0.682
Yeast
protein localization to nucleus GO:0034504 136 0.659
Yeast
rrna metabolic process GO:0016072 40 0.637
Yeast
response to abiotic stimulus GO:0009628 336 0.598
apoptotic signaling pathway GO:0097190 268 0.589
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.550
mitotic nuclear division GO:0007067 119 0.525
Yeast
protein localization to organelle GO:0033365 280 0.521
Yeast
rna catabolic process GO:0006401 71 0.514
Yeast
circulatory system development GO:0072359 262 0.509
cytoplasmic transport GO:0016482 379 0.508
Rat
protein k63 linked deubiquitination GO:0070536 21 0.457
neurological system process GO:0050877 163 0.429
golgi organization GO:0007030 38 0.425
aging GO:0007568 66 0.415
protein autoubiquitination GO:0051865 37 0.412
macromolecular complex disassembly GO:0032984 60 0.408
Yeast
protein complex disassembly GO:0043241 52 0.393
Yeast
defense response GO:0006952 315 0.384
spindle organization GO:0007051 53 0.361
Yeast
ncrna metabolic process GO:0034660 108 0.352
Yeast
single organism cellular localization GO:1902580 332 0.340
nuclear division GO:0000280 128 0.334
Yeast Worm
regulation of proteolysis GO:0030162 293 0.334
cellular glucan metabolic process GO:0006073 22 0.311
negative regulation of cell death GO:0060548 345 0.307
intrinsic apoptotic signaling pathway GO:0097193 127 0.300
locomotory behavior GO:0007626 1 0.290
protein polyubiquitination GO:0000209 110 0.273
negative regulation of intracellular signal transduction GO:1902532 183 0.262
endomembrane system organization GO:0010256 196 0.259
embryo development GO:0009790 123 0.256
Zebrafish Worm
carbohydrate derivative biosynthetic process GO:1901137 207 0.252
negative regulation of cellular component organization GO:0051129 235 0.252
nucleus organization GO:0006997 28 0.243
regulation of protein maturation GO:1903317 150 0.243
regulation of map kinase activity GO:0043405 108 0.237
cell development GO:0048468 328 0.236
mitotic sister chromatid segregation GO:0000070 53 0.234
Yeast
trabecula morphogenesis GO:0061383 2 0.229
organelle localization GO:0051640 84 0.224
Yeast
glycogen metabolic process GO:0005977 22 0.223
glucan metabolic process GO:0044042 22 0.217
protein import GO:0017038 130 0.206
nuclear import GO:0051170 106 0.205
adult locomotory behavior GO:0008344 1 0.202
attachment of spindle microtubules to kinetochore GO:0008608 17 0.196
Yeast
regulation of transferase activity GO:0051338 355 0.192
membrane organization GO:0061024 292 0.192
Yeast
membrane fusion GO:0061025 43 0.189
Yeast
protein modification by small protein removal GO:0070646 92 0.188
negative regulation of protein metabolic process GO:0051248 391 0.185
autophagy GO:0006914 88 0.162
Yeast
cardiac ventricle morphogenesis GO:0003208 20 0.161
protein k48 linked deubiquitination GO:0071108 19 0.160
cognition GO:0050890 43 0.159
regulation of protein catabolic process GO:0042176 155 0.158
neuron differentiation GO:0030182 138 0.152
leukocyte apoptotic process GO:0071887 31 0.150
cellular response to starvation GO:0009267 58 0.147
Yeast
positive regulation of transferase activity GO:0051347 227 0.143
positive regulation of protein kinase activity GO:0045860 190 0.139
protein homooligomerization GO:0051260 100 0.133
Rat
rrna catabolic process GO:0016075 6 0.124
Yeast
cellular polysaccharide metabolic process GO:0044264 27 0.123
response to organonitrogen compound GO:0010243 156 0.121
negative regulation of programmed cell death GO:0043069 321 0.117
cell type specific apoptotic process GO:0097285 125 0.111
positive regulation of phosphorylation GO:0042327 394 0.110
macrophage apoptotic process GO:0071888 1 0.110
generation of neurons GO:0048699 152 0.106
polysaccharide metabolic process GO:0005976 33 0.106
neuron projection development GO:0031175 106 0.104
energy reserve metabolic process GO:0006112 22 0.100
dna repair GO:0006281 198 0.100
activation of signaling protein activity involved in unfolded protein response GO:0006987 3 0.098
response to starvation GO:0042594 59 0.098
Yeast
negative regulation of response to wounding GO:1903035 47 0.098
protein targeting GO:0006605 187 0.097
vesicle mediated transport GO:0016192 371 0.096
Rat
small gtpase mediated signal transduction GO:0007264 78 0.095
behavior GO:0007610 112 0.094
inflammatory cell apoptotic process GO:0006925 3 0.094
maintenance of location GO:0051235 112 0.092
Yeast
cellular response to oxygen containing compound GO:1901701 276 0.091
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.091
reactive oxygen species metabolic process GO:0072593 75 0.090
microtubule based process GO:0007017 210 0.090
Yeast
cellular response to oxygen levels GO:0071453 55 0.090
response to lipid GO:0033993 206 0.088
regulation of acute inflammatory response to antigenic stimulus GO:0002864 1 0.088
positive regulation of protein localization to nucleus GO:1900182 48 0.084
Yeast
protein import into nucleus GO:0006606 104 0.083
glucose homeostasis GO:0042593 31 0.083
protein glycosylation GO:0006486 62 0.082
negative regulation of protein catabolic process GO:0042177 59 0.082
cell morphogenesis GO:0000902 296 0.081
regulation of immune response GO:0050776 201 0.081
mapk cascade GO:0000165 288 0.080
regulation of apoptotic signaling pathway GO:2001233 175 0.080
negative regulation of cellular protein metabolic process GO:0032269 353 0.077
post embryonic development GO:0009791 2 0.075
Worm
protein autophosphorylation GO:0046777 123 0.075
microtubule organizing center organization GO:0031023 62 0.074
response to oxygen containing compound GO:1901700 369 0.073
negative regulation of protein processing GO:0010955 142 0.072
negative regulation of cellular catabolic process GO:0031330 83 0.072
alcohol metabolic process GO:0006066 114 0.071
negative regulation of apoptotic process GO:0043066 316 0.071
negative regulation of protein maturation GO:1903318 142 0.069
cellular homeostasis GO:0019725 196 0.069
negative regulation of multicellular organismal process GO:0051241 317 0.066
amine metabolic process GO:0009308 44 0.066
cellular response to heat GO:0034605 14 0.066
regulation of cellular protein catabolic process GO:1903362 96 0.065
regulation of protein transport GO:0051223 213 0.065
embryo development ending in birth or egg hatching GO:0009792 34 0.065
Worm
endoplasmic reticulum organization GO:0007029 20 0.064
immune response GO:0006955 307 0.064
regulation of protein targeting GO:1903533 91 0.063
mitotic spindle organization GO:0007052 27 0.063
Yeast
regulation of nucleocytoplasmic transport GO:0046822 98 0.063
ribonucleoside monophosphate catabolic process GO:0009158 158 0.062
Yeast Rat Worm
muscle structure development GO:0061061 98 0.061
heart trabecula morphogenesis GO:0061384 1 0.060
establishment of organelle localization GO:0051656 59 0.060
Yeast
protein deubiquitination GO:0016579 79 0.060
photoreceptor cell differentiation GO:0046530 2 0.060
negative regulation of acute inflammatory response GO:0002674 3 0.059
regulation of protein processing GO:0070613 150 0.057
cellular component morphogenesis GO:0032989 314 0.057
cell part morphogenesis GO:0032990 137 0.056
single organism reproductive process GO:0044702 98 0.056
Worm
chromosome segregation GO:0007059 114 0.055
Yeast
negative regulation of leukocyte apoptotic process GO:2000107 16 0.055
response to heat GO:0009408 21 0.055
cardiovascular system development GO:0072358 262 0.054
neuron development GO:0048666 113 0.054
positive regulation of hydrolase activity GO:0051345 331 0.054
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.053
carbohydrate homeostasis GO:0033500 31 0.053
regulation of kinase activity GO:0043549 314 0.053
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.052
Yeast
reproduction GO:0000003 63 0.052
Worm
maintenance of protein location GO:0045185 57 0.051
Yeast
positive regulation of kinase activity GO:0033674 204 0.051
negative regulation of protein transport GO:0051224 75 0.050
response to nitrogen compound GO:1901698 184 0.049
negative regulation of catabolic process GO:0009895 104 0.048
endocytosis GO:0006897 159 0.048
cellular response to cytokine stimulus GO:0071345 181 0.048
regulation of synaptic plasticity GO:0048167 3 0.048
cellular response to oxidative stress GO:0034599 85 0.047
visual learning GO:0008542 1 0.046
nucleocytoplasmic transport GO:0006913 176 0.046
cellular response to decreased oxygen levels GO:0036294 51 0.045
response to cytokine GO:0034097 232 0.045
blood vessel development GO:0001568 172 0.045
cytokine production GO:0001816 247 0.044
translation GO:0006412 132 0.043
response to nutrient levels GO:0031667 81 0.043
Yeast
protein k11 linked deubiquitination GO:0035871 9 0.043
regulation of cell cycle phase transition GO:1901987 126 0.043
cell projection organization GO:0030030 252 0.043
protein refolding GO:0042026 14 0.043
membrane invagination GO:0010324 10 0.042
Yeast
positive regulation of programmed cell death GO:0043068 249 0.042
Mouse
establishment of protein localization to organelle GO:0072594 172 0.042
positive regulation of protein catabolic process GO:0045732 75 0.042
reproductive structure development GO:0048608 55 0.041
Worm
lipid localization GO:0010876 106 0.041
ribonucleotide catabolic process GO:0009261 405 0.040
Yeast Rat Worm
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.040
blastoderm segmentation GO:0007350 2 0.040
protein n linked glycosylation via asparagine GO:0018279 10 0.040
reactive nitrogen species metabolic process GO:2001057 3 0.039
growth GO:0040007 202 0.039
Worm
protein k48 linked ubiquitination GO:0070936 38 0.039
cell cell signaling GO:0007267 155 0.038
oogenesis GO:0048477 2 0.038
nucleoside monophosphate catabolic process GO:0009125 159 0.038
Yeast Rat Worm
negative regulation of cell cycle GO:0045786 193 0.038
negative regulation of cell proliferation GO:0008285 228 0.038
system process GO:0003008 349 0.037
cellular response to organic cyclic compound GO:0071407 127 0.037
blood vessel morphogenesis GO:0048514 162 0.036
response to external biotic stimulus GO:0043207 261 0.036
cellular response to external stimulus GO:0071496 111 0.036
Yeast
cellular response to hypoxia GO:0071456 51 0.035
single organism nuclear import GO:1902593 104 0.035
protein folding GO:0006457 38 0.035
positive regulation of protein ubiquitination GO:0031398 53 0.035
Yeast
innate immune response GO:0045087 178 0.035
nervous system development GO:0007399 293 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
negative regulation of proteolysis GO:0045861 132 0.034
protein targeting to nucleus GO:0044744 104 0.034
nucleoside phosphate catabolic process GO:1901292 412 0.034
Yeast Rat Worm
signal transduction by phosphorylation GO:0023014 297 0.033
protein dephosphorylation GO:0006470 81 0.033
response to decreased oxygen levels GO:0036293 96 0.032
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.032
negative regulation of protein ubiquitination GO:0031397 35 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.032
single organism behavior GO:0044708 28 0.032
atp metabolic process GO:0046034 176 0.032
Yeast Rat Worm
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.031
tripartite regional subdivision GO:0007351 2 0.031
protein localization to membrane GO:0072657 160 0.031
organelle inheritance GO:0048308 2 0.031
i kappab kinase nf kappab signaling GO:0007249 166 0.031
chemical homeostasis GO:0048878 306 0.031
ras protein signal transduction GO:0007265 73 0.031
anterior posterior axis specification GO:0009948 2 0.031
energy derivation by oxidation of organic compounds GO:0015980 43 0.030
monocarboxylic acid metabolic process GO:0032787 185 0.029
cellular response to organonitrogen compound GO:0071417 124 0.029
negative regulation of growth GO:0045926 97 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.029
regulation of mitotic sister chromatid separation GO:0010965 27 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
regulation of translation GO:0006417 89 0.029
maintenance of location in cell GO:0051651 62 0.029
Yeast
response to radiation GO:0009314 151 0.029
cellular amino acid metabolic process GO:0006520 116 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.028
cellular response to nitrogen compound GO:1901699 144 0.028
regulation of protein import into nucleus GO:0042306 78 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.028
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.027
positive regulation of cell death GO:0010942 263 0.027
Mouse
mitotic metaphase plate congression GO:0007080 14 0.027
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.027
Yeast Rat Worm
negative regulation of transport GO:0051051 176 0.027
response to oxidative stress GO:0006979 121 0.027
cellular response to molecule of bacterial origin GO:0071219 62 0.026
regulation of oxidative stress induced cell death GO:1903201 24 0.026
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.026
protein monoubiquitination GO:0006513 39 0.026
inflammatory response GO:0006954 79 0.026
metal ion homeostasis GO:0055065 169 0.026
regulation of protein kinase activity GO:0045859 289 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
negative regulation of apoptotic signaling pathway GO:2001234 97 0.025
cellular response to lipopolysaccharide GO:0071222 57 0.025
extrinsic apoptotic signaling pathway GO:0097191 119 0.025
negative regulation of immune system process GO:0002683 136 0.024
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.024
nuclear transport GO:0051169 179 0.024
regulation of nervous system development GO:0051960 88 0.024
regulation of leukocyte apoptotic process GO:2000106 25 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
negative regulation of response to external stimulus GO:0032102 83 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
response to light stimulus GO:0009416 87 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
Yeast Rat Worm
actin filament based process GO:0030029 224 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
multi organism reproductive process GO:0044703 54 0.022
regulation of epithelial cell migration GO:0010632 93 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.022
female gamete generation GO:0007292 2 0.022
developmental process involved in reproduction GO:0003006 66 0.021
Worm
cell activation GO:0001775 213 0.021
spermatid differentiation GO:0048515 4 0.021
nucleus localization GO:0051647 1 0.021
de novo posttranslational protein folding GO:0051084 2 0.021
positive regulation of binding GO:0051099 45 0.021
oocyte development GO:0048599 1 0.021
response to biotic stimulus GO:0009607 276 0.021
cellular response to nutrient levels GO:0031669 69 0.021
Yeast
regulation of mitotic cell cycle GO:0007346 189 0.021
regulation of cellular amine metabolic process GO:0033238 11 0.021
neuron projection morphogenesis GO:0048812 50 0.020
cellular chemical homeostasis GO:0055082 180 0.020
cellular response to biotic stimulus GO:0071216 71 0.020
cell projection morphogenesis GO:0048858 129 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
regulation of cell cycle GO:0051726 393 0.020
spermatid development GO:0007286 4 0.020
development of primary sexual characteristics GO:0045137 35 0.019
Worm
axonogenesis GO:0007409 31 0.019
axon cargo transport GO:0008088 2 0.019
cell growth GO:0016049 160 0.019
response to organic cyclic compound GO:0014070 204 0.019
biological adhesion GO:0022610 331 0.019
cell death in response to oxidative stress GO:0036473 29 0.019
response to hypoxia GO:0001666 96 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.019
segmentation GO:0035282 4 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
rna processing GO:0006396 255 0.018
cellular response to ethanol GO:0071361 1 0.018
apoptotic mitochondrial changes GO:0008637 57 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
response to oxygen levels GO:0070482 100 0.018
response to hormone GO:0009725 175 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
Mouse
multicellular organism reproduction GO:0032504 42 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.018
central nervous system development GO:0007417 123 0.018
ossification GO:0001503 121 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
lymphocyte activation GO:0046649 133 0.017
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.017
synaptic transmission GO:0007268 61 0.017
regulation of mapk cascade GO:0043408 262 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.017
cell morphogenesis involved in differentiation GO:0000904 144 0.017
nucleoside catabolic process GO:0009164 408 0.017
Yeast Rat Worm
striated muscle myosin thick filament assembly GO:0071688 2 0.017
male meiosis GO:0007140 1 0.017
positive regulation of protein binding GO:0032092 24 0.016
protein k63 linked ubiquitination GO:0070534 31 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
regulation of cell adhesion GO:0030155 166 0.016
toxin transport GO:1901998 4 0.016
spermatogenesis GO:0007283 22 0.016
actin cytoskeleton organization GO:0030036 207 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
regulation of cytokine production GO:0001817 232 0.016
golgi vesicle transport GO:0048193 80 0.016
Rat
activation of protein kinase activity GO:0032147 90 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.015
head development GO:0060322 108 0.015
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 3 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
cellular ketone metabolic process GO:0042180 80 0.015
hindbrain development GO:0030902 3 0.015
positive regulation of lipid biosynthetic process GO:0046889 22 0.015
cellular response to lipid GO:0071396 127 0.015
response to uv GO:0009411 73 0.015
negative regulation of defense response GO:0031348 47 0.015
neurogenesis GO:0022008 169 0.015
response to wounding GO:0009611 168 0.015
atp catabolic process GO:0006200 157 0.015
Yeast Rat Worm
phagocytosis GO:0006909 42 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
negative regulation of cytoplasmic transport GO:1903650 46 0.014
nitrogen compound transport GO:0071705 191 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
Yeast Rat Worm
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
cell division GO:0051301 168 0.014
gonad development GO:0008406 34 0.014
Worm
response to growth factor GO:0070848 205 0.014
defense response to bacterium GO:0042742 63 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
cytokinesis GO:0000910 96 0.014
response to bacterium GO:0009617 144 0.014
peptidyl tyrosine modification GO:0018212 170 0.013
epithelial cell migration GO:0010631 119 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.013
positive regulation of immune response GO:0050778 159 0.013
reproductive system development GO:0061458 56 0.013
Worm
vasculature development GO:0001944 181 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
Yeast Rat Worm
positive regulation of cellular component movement GO:0051272 181 0.013
centrosome organization GO:0051297 58 0.013
organ morphogenesis GO:0009887 147 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
regulation of protein complex assembly GO:0043254 147 0.013
cellular component disassembly GO:0022411 92 0.013
Yeast
metaphase plate congression GO:0051310 18 0.013
Yeast
negative regulation of protein modification process GO:0031400 200 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
Yeast Rat Worm
receptor mediated endocytosis GO:0006898 84 0.013
behavioral defense response GO:0002209 0 0.013
microtubule based transport GO:0010970 21 0.012
regulation of protein binding GO:0043393 66 0.012
mitochondrion organization GO:0007005 156 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
Yeast Rat Worm
cell aging GO:0007569 52 0.012
spindle assembly GO:0051225 29 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
cellular protein complex assembly GO:0043623 188 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
Yeast Rat Worm
ventricular cardiac muscle tissue development GO:0003229 14 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
regulation of cell migration GO:0030334 289 0.012
male gamete generation GO:0048232 22 0.012
negative regulation of protein localization to nucleus GO:1900181 34 0.012
positive regulation of immune system process GO:0002684 283 0.011
regulation of transmembrane transporter activity GO:0022898 74 0.011
lipid metabolic process GO:0006629 381 0.011
cellular response to alcohol GO:0097306 29 0.011
response to other organism GO:0051707 261 0.011
regulation of protein stability GO:0031647 87 0.011
regulation of nf kappab import into nucleus GO:0042345 22 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
reproductive process GO:0022414 106 0.011
Worm
multicellular organismal reproductive process GO:0048609 40 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
endosomal transport GO:0016197 129 0.011
regulation of immune effector process GO:0002697 91 0.011
meiotic nuclear division GO:0007126 10 0.011
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.011
leukocyte activation GO:0045321 164 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
Yeast Rat Worm
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
regulation of transcription factor import into nucleus GO:0042990 39 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.010
protein acylation GO:0043543 138 0.010
regulation of cell motility GO:2000145 299 0.010

VCP disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.174
neurodegenerative disease DOID:1289 102 0.174
nervous system disease DOID:863 431 0.174
disease of cellular proliferation DOID:14566 174 0.081
myopathy DOID:423 104 0.030
muscular disease DOID:0080000 114 0.030
musculoskeletal system disease DOID:17 223 0.030
muscle tissue disease DOID:66 113 0.030
cancer DOID:162 167 0.026
organ system cancer DOID:0050686 164 0.026
neuropathy DOID:870 52 0.014
musculoskeletal system cancer DOID:0060100 11 0.012
motor neuron disease DOID:231 27 0.002
amyotrophic lateral sclerosis DOID:332 20 0.002
syndrome DOID:225 17 0.000