|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.998
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.955
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.922
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.907
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.886
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.852
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.810
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.807
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.799
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.795
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.724
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.670
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.668
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.644
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.643
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.545
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.543
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.537
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.512
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.496
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.483
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.472
|
Mouse |
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.469
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.460
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.446
|
Mouse |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.444
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.441
|
Zebrafish |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.433
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.430
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.427
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.426
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.422
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.421
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.410
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.393
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.386
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
12 |
0.381
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.376
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.371
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.369
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.364
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.362
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.359
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.359
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.349
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.339
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.339
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.336
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.332
|
Mouse |
|
|
behavior
|
GO:0007610 |
112 |
0.330
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.325
|
|
|
|
system process
|
GO:0003008 |
349 |
0.325
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.316
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.316
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.312
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.301
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.298
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.283
|
Mouse |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.278
|
Mouse |
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.274
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.271
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.270
|
|
|
|
sphingolipid mediated signaling pathway
|
GO:0090520 |
1 |
0.270
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.266
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.261
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.260
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.259
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.254
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.246
|
|
|
|
positive regulation of cell migration involved in sprouting angiogenesis
|
GO:0090050 |
3 |
0.245
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.244
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.244
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.240
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.240
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
9 |
0.239
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.234
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.234
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.231
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.229
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.229
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.229
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.229
|
Mouse |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.226
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.225
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.224
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.223
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.223
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.223
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.223
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.216
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.214
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.214
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.212
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.209
|
Mouse |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.205
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.199
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.198
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.197
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.197
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.195
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.195
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.189
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.189
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.186
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.184
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.182
|
|
|
|
myotube cell development
|
GO:0014904 |
14 |
0.180
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.180
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.179
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.174
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.174
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.173
|
|
|
|
memory
|
GO:0007613 |
3 |
0.171
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.171
|
Mouse |
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.169
|
Mouse |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.166
|
Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.165
|
Zebrafish |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.158
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.157
|
Zebrafish Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.156
|
Mouse |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.156
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.154
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.153
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.151
|
Mouse |
|
|
regulation of myotube differentiation
|
GO:0010830 |
18 |
0.150
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.150
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.150
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.149
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.149
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.148
|
|
|
|
chromatin silencing at rdna
|
GO:0000183 |
5 |
0.147
|
|
|
|
histone h4 deacetylation
|
GO:0070933 |
8 |
0.146
|
|
|
|
negative regulation of muscle cell differentiation
|
GO:0051148 |
17 |
0.144
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.143
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.140
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.139
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.138
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.137
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.137
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.136
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.133
|
|
|
|
negative regulation of chromatin silencing at rdna
|
GO:0061188 |
2 |
0.132
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.129
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.126
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.126
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.124
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.122
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.122
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.120
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.119
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.117
|
|
|
|
head development
|
GO:0060322 |
108 |
0.116
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.115
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.114
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.110
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.108
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.108
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.108
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.106
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.106
|
|
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.106
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.105
|
Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.105
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.104
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.103
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.102
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.102
|
Mouse |
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.102
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.101
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.101
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.100
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
12 |
0.099
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.098
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.097
|
Zebrafish Mouse |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.097
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.096
|
Mouse |
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.096
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.094
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.094
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.094
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.094
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.093
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.092
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.092
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.091
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.091
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.091
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.087
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.086
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.086
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.085
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.085
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.085
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.085
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.084
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.084
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.082
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.082
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.082
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.082
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.080
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.080
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.080
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.079
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.079
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.079
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
21 |
0.078
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.077
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.077
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.076
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.075
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.075
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.074
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.073
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.072
|
Mouse |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.072
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.072
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.071
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.071
|
Mouse |
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.070
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.070
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.070
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.069
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.069
|
|
|
|
negative regulation of striated muscle cell differentiation
|
GO:0051154 |
8 |
0.069
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.069
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.069
|
Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.068
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.068
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.067
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.067
|
Zebrafish Mouse |
|
|
regulation of chromatin silencing at rdna
|
GO:0061187 |
2 |
0.066
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.066
|
|
|
|
lung cell differentiation
|
GO:0060479 |
1 |
0.065
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.065
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.064
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.064
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.064
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.064
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.064
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.063
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.063
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.063
|
|
|
|
histone h3 deacetylation
|
GO:0070932 |
9 |
0.063
|
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.063
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.063
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.062
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.062
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.062
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.059
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.059
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.059
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.058
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.058
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.058
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.058
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.058
|
|
|
|
demethylation
|
GO:0070988 |
37 |
0.057
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.057
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.057
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.056
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.054
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.054
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.053
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.053
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.053
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.053
|
Mouse |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.052
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.052
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.052
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.052
|
Mouse |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.051
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.051
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.051
|
Mouse |
|
|
cell activation
|
GO:0001775 |
213 |
0.051
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.050
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.050
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.050
|
|
|
|
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment
|
GO:0061317 |
3 |
0.050
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.049
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.049
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.049
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.048
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.048
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.048
|
Mouse |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.048
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.048
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.048
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.047
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.047
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.047
|
|
|
|
glycolytic process
|
GO:0006096 |
17 |
0.047
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.046
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.046
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.046
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.045
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.045
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.045
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.045
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
7 |
0.045
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.045
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.044
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.044
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.044
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.044
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.044
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.044
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.044
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.044
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.043
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.043
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.042
|
Mouse |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.042
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.042
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.042
|
Mouse |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.041
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.041
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.040
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.040
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.040
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.040
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.040
|
Zebrafish |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.040
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.040
|
Mouse |
|
|
regulation of protein sumoylation
|
GO:0033233 |
13 |
0.038
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.038
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.038
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.038
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.038
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.037
|
Zebrafish |
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.037
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.037
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.037
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.037
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.037
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.037
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.037
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.036
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.036
|
Mouse |
|
|
hippocampus development
|
GO:0021766 |
1 |
0.036
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.036
|
|
|
|
histone h3 k27 demethylation
|
GO:0071557 |
3 |
0.036
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.036
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.036
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.036
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.035
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.035
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.035
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.035
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.035
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.035
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.034
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.034
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.034
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.034
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.034
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.034
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.034
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.034
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.033
|
Zebrafish |
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.033
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.033
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.033
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.033
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.033
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.033
|
|
|
|
negative regulation of cell migration involved in sprouting angiogenesis
|
GO:0090051 |
6 |
0.032
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.032
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.032
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.032
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.032
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.032
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.032
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.031
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.031
|
Mouse |
|
|
wound healing
|
GO:0042060 |
115 |
0.031
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.031
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.031
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.031
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.030
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.030
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.030
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.030
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.030
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.029
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.029
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.029
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.029
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.029
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.029
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.029
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.028
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.028
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.028
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.028
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.028
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.027
|
Mouse |
|
|
drug catabolic process
|
GO:0042737 |
10 |
0.027
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.027
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.027
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.027
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.027
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.027
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.027
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.027
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.026
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.026
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.026
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.026
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.026
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.026
|
Mouse |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.026
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.026
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.026
|
Mouse |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.025
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.025
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.025
|
Mouse |
|
|
peptidyl lysine deacetylation
|
GO:0034983 |
6 |
0.025
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.025
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.025
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.025
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.025
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.024
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.024
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.024
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.024
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.024
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.024
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.024
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.024
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.024
|
Zebrafish |
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
6 |
0.024
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.024
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.023
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.023
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.023
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.023
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.023
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.023
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.023
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.023
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.023
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.023
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.022
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.022
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.022
|
|
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.022
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.022
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.022
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.022
|
Zebrafish |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.022
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.021
|
Zebrafish Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.021
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
14 |
0.021
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.021
|
Mouse |
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.021
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.021
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.021
|
Mouse |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.021
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.021
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.021
|
Zebrafish |
|
|
growth
|
GO:0040007 |
202 |
0.021
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.021
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.021
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.021
|
Mouse |
|
|
nephric duct development
|
GO:0072176 |
4 |
0.021
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.021
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.021
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.021
|
Mouse |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.021
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.021
|
|
|
|
regulation of cellular carbohydrate catabolic process
|
GO:0043471 |
11 |
0.021
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.020
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.020
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.020
|
Mouse |
|
|
negative regulation of cholesterol storage
|
GO:0010887 |
4 |
0.020
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
14 |
0.020
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.020
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.020
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.020
|
|
