Homo sapiens

47 known processes

DEDD2

death effector domain containing 2

(Aliases: FLAME-3)

DEDD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.090
cellular amine metabolic process GO:0044106 41 0.070
amine metabolic process GO:0009308 44 0.066
regulation of cellular amino acid metabolic process GO:0006521 6 0.064
regulation of cellular amine metabolic process GO:0033238 11 0.055
regulation of cellular ketone metabolic process GO:0010565 50 0.052
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
cellular amino acid metabolic process GO:0006520 116 0.048
purine ribonucleoside metabolic process GO:0046128 437 0.043
nucleoside triphosphate metabolic process GO:0009141 422 0.041
cellular macromolecule catabolic process GO:0044265 380 0.040
post embryonic development GO:0009791 2 0.039
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
protein catabolic process GO:0030163 325 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
organophosphate catabolic process GO:0046434 430 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.036
glycosyl compound catabolic process GO:1901658 413 0.035
multicellular organismal aging GO:0010259 3 0.034
nucleotide catabolic process GO:0009166 408 0.034
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
positive regulation of hydrolase activity GO:0051345 331 0.033
purine ribonucleotide catabolic process GO:0009154 404 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
purine containing compound catabolic process GO:0072523 411 0.033
ribonucleoside catabolic process GO:0042454 406 0.033
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
vesicle mediated transport GO:0016192 371 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
apoptotic signaling pathway GO:0097190 268 0.031
purine nucleoside catabolic process GO:0006152 398 0.030
cellular protein catabolic process GO:0044257 261 0.029
single organism membrane organization GO:0044802 268 0.029
determination of adult lifespan GO:0008340 2 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
nucleoside catabolic process GO:0009164 408 0.029
covalent chromatin modification GO:0016569 254 0.029
membrane organization GO:0061024 292 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
regulation of proteolysis GO:0030162 293 0.028
positive regulation of catabolic process GO:0009896 310 0.028
oogenesis GO:0048477 2 0.028
actin filament based process GO:0030029 224 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
chemical homeostasis GO:0048878 306 0.028
protein maturation GO:0051604 233 0.027
ras protein signal transduction GO:0007265 73 0.027
regulation of cellular response to stress GO:0080135 244 0.027
histone modification GO:0016570 251 0.027
cell development GO:0048468 328 0.027
defense response GO:0006952 315 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
locomotory behavior GO:0007626 1 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
regulation of cellular component biogenesis GO:0044087 281 0.025
small gtpase mediated signal transduction GO:0007264 78 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
segmentation GO:0035282 4 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.024
regulation of kinase activity GO:0043549 314 0.024
protein processing GO:0016485 226 0.024
cellular component morphogenesis GO:0032989 314 0.024
rho protein signal transduction GO:0007266 26 0.023
lipid metabolic process GO:0006629 381 0.023
regulation of cell differentiation GO:0045595 393 0.023
positive regulation of cell death GO:0010942 263 0.023
female gamete generation GO:0007292 2 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
mapk cascade GO:0000165 288 0.022
organelle assembly GO:0070925 176 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
response to biotic stimulus GO:0009607 276 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
neurotransmitter secretion GO:0007269 4 0.022
single organism cellular localization GO:1902580 332 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
response to external biotic stimulus GO:0043207 261 0.021
regulation of protein catabolic process GO:0042176 155 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
regulation of transferase activity GO:0051338 355 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
response to other organism GO:0051707 261 0.021
chromatin organization GO:0006325 351 0.020
negative regulation of cell death GO:0060548 345 0.020
neuromuscular junction development GO:0007528 3 0.020
cytoplasmic transport GO:0016482 379 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
response to abiotic stimulus GO:0009628 336 0.020
cellular lipid metabolic process GO:0044255 303 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
guanosine containing compound catabolic process GO:1901069 239 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
protein localization to organelle GO:0033365 280 0.020
mitotic cell cycle GO:0000278 326 0.020
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
cellular protein complex assembly GO:0043623 188 0.019
regulation of protein kinase activity GO:0045859 289 0.019
interspecies interaction between organisms GO:0044419 156 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
cell projection organization GO:0030030 252 0.019
secretion by cell GO:0032940 226 0.019
autophagy GO:0006914 88 0.019
regulation of cell cycle GO:0051726 393 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
viral life cycle GO:0019058 132 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
positive regulation of immune system process GO:0002684 283 0.018
protein ubiquitination GO:0016567 314 0.018
mitotic cell cycle process GO:1903047 286 0.018
endomembrane system organization GO:0010256 196 0.018
regulation of protein localization GO:0032880 296 0.018
cellular response to external stimulus GO:0071496 111 0.018
response to oxygen containing compound GO:1901700 369 0.018
maintenance of location GO:0051235 112 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
gtp catabolic process GO:0006184 237 0.017
positive regulation of transport GO:0051050 336 0.017
system process GO:0003008 349 0.017
intracellular protein transport GO:0006886 270 0.017
innate immune response GO:0045087 178 0.017
positive regulation of transferase activity GO:0051347 227 0.017
regeneration GO:0031099 4 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
negative regulation of protein maturation GO:1903318 142 0.017
negative regulation of protein modification process GO:0031400 200 0.017
multi organism cellular process GO:0044764 156 0.017
transmembrane transport GO:0055085 399 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
regulation of cell motility GO:2000145 299 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
memory GO:0007613 3 0.016
regulation of protein processing GO:0070613 150 0.016
secretion GO:0046903 254 0.016
blastoderm segmentation GO:0007350 2 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
immune response GO:0006955 307 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of response to external stimulus GO:0032101 222 0.016
small molecule biosynthetic process GO:0044283 157 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
chromatin modification GO:0016568 298 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
carbohydrate metabolic process GO:0005975 207 0.015
oocyte development GO:0048599 1 0.015
spermatid differentiation GO:0048515 4 0.015
rna processing GO:0006396 255 0.015
regulation of protein maturation GO:1903317 150 0.015
gtp metabolic process GO:0046039 239 0.015
peptidyl lysine modification GO:0018205 144 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
atp metabolic process GO:0046034 176 0.015
negative regulation of cell cycle GO:0045786 193 0.015
regulation of cell cycle process GO:0010564 266 0.015
negative regulation of protein processing GO:0010955 142 0.015
dephosphorylation GO:0016311 209 0.015
positive regulation of developmental process GO:0051094 314 0.015
myosin filament organization GO:0031033 2 0.015
biological adhesion GO:0022610 331 0.015
ion homeostasis GO:0050801 230 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
cell morphogenesis GO:0000902 296 0.015
hindbrain development GO:0030902 3 0.014
oocyte differentiation GO:0009994 2 0.014
spermatid development GO:0007286 4 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of mapk cascade GO:0043408 262 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
viral process GO:0016032 146 0.014
myosin filament assembly GO:0031034 2 0.014
rna interference GO:0016246 4 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
dna repair GO:0006281 198 0.014
neuroblast proliferation GO:0007405 4 0.014
regulation of cellular component movement GO:0051270 334 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
peptidyl serine modification GO:0018209 106 0.014
regulation of protein transport GO:0051223 213 0.014
macroautophagy GO:0016236 39 0.014
regulation of secretion GO:0051046 194 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
cytokine production GO:0001816 247 0.014
response to bacterium GO:0009617 144 0.014
negative regulation of phosphorylation GO:0042326 174 0.013
positive regulation of kinase activity GO:0033674 204 0.013
mating GO:0007618 1 0.013
rhythmic behavior GO:0007622 2 0.013
cellular component disassembly GO:0022411 92 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
immune system development GO:0002520 195 0.013
response to fungus GO:0009620 4 0.013
protein targeting GO:0006605 187 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
endosomal transport GO:0016197 129 0.013
adult locomotory behavior GO:0008344 1 0.013
compound eye development GO:0048749 1 0.013
oxidation reduction process GO:0055114 396 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
rna splicing GO:0008380 131 0.013
anterior posterior axis specification GO:0009948 2 0.013
peripheral nervous system development GO:0007422 2 0.013
wnt signaling pathway GO:0016055 156 0.013
nervous system development GO:0007399 293 0.013
mitochondrion organization GO:0007005 156 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
cell projection morphogenesis GO:0048858 129 0.013
regulation of immune response GO:0050776 201 0.013
negative regulation of proteolysis GO:0045861 132 0.013
microtubule based process GO:0007017 210 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of intracellular transport GO:0032386 195 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
growth GO:0040007 202 0.012
tissue regeneration GO:0042246 3 0.012
cellular response to nutrient levels GO:0031669 69 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
cell fate determination GO:0001709 3 0.012
negative regulation of catabolic process GO:0009895 104 0.012
protein autophosphorylation GO:0046777 123 0.012
regulation of growth GO:0040008 165 0.012
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.012
regulation of gtpase activity GO:0043087 180 0.012
defense response to other organism GO:0098542 129 0.012
cell growth GO:0016049 160 0.012
regulation of locomotion GO:0040012 329 0.012
response to nutrient levels GO:0031667 81 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
protein acetylation GO:0006473 116 0.012
regulation of cell growth GO:0001558 135 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
nuclear transport GO:0051169 179 0.012
positive regulation of organelle organization GO:0010638 195 0.012
epithelium development GO:0060429 227 0.012
glycerolipid metabolic process GO:0046486 107 0.012
negative regulation of transferase activity GO:0051348 124 0.012
protein localization to membrane GO:0072657 160 0.012
regulation of autophagy GO:0010506 52 0.012
cellular response to starvation GO:0009267 58 0.012
negative regulation of developmental process GO:0051093 247 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
generation of neurons GO:0048699 152 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
internal protein amino acid acetylation GO:0006475 101 0.012
organ formation GO:0048645 3 0.012
tripartite regional subdivision GO:0007351 2 0.012
cell adhesion GO:0007155 325 0.012
hemopoiesis GO:0030097 180 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
protein acylation GO:0043543 138 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012
regulation of gtp catabolic process GO:0033124 180 0.011
neurological system process GO:0050877 163 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
negative regulation of organelle organization GO:0010639 126 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
myoblast fusion GO:0007520 1 0.011
cell division GO:0051301 168 0.011
inner ear morphogenesis GO:0042472 4 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
organic acid biosynthetic process GO:0016053 97 0.011
regulation of transcription during mitosis GO:0045896 2 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
lipid biosynthetic process GO:0008610 177 0.011
response to extracellular stimulus GO:0009991 85 0.011
endocytosis GO:0006897 159 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regulation of peptidase activity GO:0052547 180 0.011
response to starvation GO:0042594 59 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
cellular response to extracellular stimulus GO:0031668 72 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
positive regulation of transcription during mitosis GO:0045897 2 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
mrna metabolic process GO:0016071 175 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
actin cytoskeleton organization GO:0030036 207 0.011
macromolecule methylation GO:0043414 97 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
visual behavior GO:0007632 2 0.011
glycoprotein metabolic process GO:0009100 110 0.011
limbic system development GO:0021761 3 0.011
ion transmembrane transport GO:0034220 338 0.011
regulation of cell migration GO:0030334 289 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
nerve development GO:0021675 4 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
regulation of cytokine production GO:0001817 232 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
fatty acid metabolic process GO:0006631 115 0.011
protein secretion GO:0009306 98 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
metencephalon development GO:0022037 2 0.010
regulation of mitotic cell cycle GO:0007346 189 0.010
negative regulation of cell growth GO:0030308 83 0.010
positive regulation of secretion GO:0051047 116 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
startle response GO:0001964 3 0.010
cellular homeostasis GO:0019725 196 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
response to hormone GO:0009725 175 0.010
nitrogen compound transport GO:0071705 191 0.010
alcohol metabolic process GO:0006066 114 0.010
t cell differentiation in thymus GO:0033077 4 0.010
sensory perception of smell GO:0007608 2 0.010
cell cycle phase transition GO:0044770 173 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
response to lipid GO:0033993 206 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
neurogenesis GO:0022008 169 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
positive regulation of neural precursor cell proliferation GO:2000179 2 0.010
regulation of peptidyl serine phosphorylation GO:0033135 50 0.010
atp catabolic process GO:0006200 157 0.010
cellular chemical homeostasis GO:0055082 180 0.010
cation homeostasis GO:0055080 189 0.010
meiosis i GO:0007127 4 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
cerebellum development GO:0021549 2 0.010

DEDD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.027
inherited metabolic disorder DOID:655 242 0.022
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
musculoskeletal system disease DOID:17 223 0.018
disease of cellular proliferation DOID:14566 174 0.018
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
cancer DOID:162 167 0.014
central nervous system disease DOID:331 186 0.013
immune system disease DOID:2914 155 0.013
organ system cancer DOID:0050686 164 0.013
gastrointestinal system disease DOID:77 36 0.013
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
connective tissue disease DOID:65 109 0.011
retinal disease DOID:5679 118 0.011
neurodegenerative disease DOID:1289 102 0.010
cardiovascular system disease DOID:1287 106 0.010
bone disease DOID:0080001 88 0.010