Homo sapiens

196 known processes

PTCH1

patched 1

(Aliases: NBCCS,PTCH,HPE7,FLJ42602,PTC,PTCH11,BCNS,PTC1,FLJ26746)

PTCH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forebrain dorsal ventral pattern formation GO:0021798 1 0.992
forebrain regionalization GO:0021871 3 0.945
cranial nerve development GO:0021545 4 0.932
neuron fate commitment GO:0048663 2 0.879
pituitary gland development GO:0021983 2 0.876
somatic stem cell maintenance GO:0035019 4 0.839
cell differentiation in spinal cord GO:0021515 1 0.798
retinal ganglion cell axon guidance GO:0031290 2 0.621
morphogenesis of embryonic epithelium GO:0016331 4 0.618
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.597
hindbrain development GO:0030902 3 0.581
nerve development GO:0021675 4 0.568
embryonic camera type eye development GO:0031076 2 0.524
inner ear morphogenesis GO:0042472 4 0.507
ventral spinal cord development GO:0021517 1 0.501
cerebellum development GO:0021549 2 0.483
neuron projection regeneration GO:0031102 1 0.472
oligodendrocyte development GO:0014003 6 0.436
regulation of cell differentiation GO:0045595 393 0.404
urogenital system development GO:0001655 65 0.403
embryonic viscerocranium morphogenesis GO:0048703 1 0.375
metencephalon development GO:0022037 2 0.346
epithelial cell fate commitment GO:0072148 3 0.322
mesenchyme development GO:0060485 59 0.320
ossification GO:0001503 121 0.287
negative regulation of developmental process GO:0051093 247 0.280
regeneration GO:0031099 4 0.272
renal system development GO:0072001 63 0.263
embryonic heart tube morphogenesis GO:0003143 8 0.262
endocardial cell differentiation GO:0060956 2 0.250
blastoderm segmentation GO:0007350 2 0.249
circulatory system development GO:0072359 262 0.248
chemotaxis GO:0006935 157 0.246
Fly
regulation of protein localization GO:0032880 296 0.245
Fly
epithelium development GO:0060429 227 0.237
epithelial cell differentiation GO:0030855 141 0.237
organ morphogenesis GO:0009887 147 0.236
Fly
regulation of establishment of protein localization GO:0070201 242 0.233
Fly
endocrine system development GO:0035270 26 0.232
cardiovascular system development GO:0072358 262 0.231
taxis GO:0042330 157 0.228
Fly
positive regulation of cellular component organization GO:0051130 376 0.225
nervous system development GO:0007399 293 0.223
regulation of mitotic cell cycle GO:0007346 189 0.214
Fly
mitotic cell cycle GO:0000278 326 0.212
Fly
blood vessel morphogenesis GO:0048514 162 0.211
tube morphogenesis GO:0035239 95 0.208
actin filament based process GO:0030029 224 0.206
mesenchymal cell differentiation GO:0048762 52 0.206
regulation of cell cycle process GO:0010564 266 0.202
semicircular canal morphogenesis GO:0048752 1 0.201
cellular component morphogenesis GO:0032989 314 0.200
Fly
vasculature development GO:0001944 181 0.198
tube development GO:0035295 125 0.196
stem cell development GO:0048864 69 0.192
blood vessel development GO:0001568 172 0.191
negative regulation of cell differentiation GO:0045596 171 0.189
neuron differentiation GO:0030182 138 0.184
Fly
cell morphogenesis GO:0000902 296 0.180
Fly
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.177
cell development GO:0048468 328 0.173
Fly
connective tissue development GO:0061448 39 0.171
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.169
cell projection organization GO:0030030 252 0.167
Fly
endomembrane system organization GO:0010256 196 0.163
actin cytoskeleton organization GO:0030036 207 0.160
stem cell differentiation GO:0048863 93 0.159
growth GO:0040007 202 0.154
single organism cellular localization GO:1902580 332 0.153
g protein coupled receptor signaling pathway GO:0007186 207 0.151
protein localization to membrane GO:0072657 160 0.149
anatomical structure formation involved in morphogenesis GO:0048646 284 0.147
cellular ketone metabolic process GO:0042180 80 0.147
mitotic cell cycle process GO:1903047 286 0.144
embryonic neurocranium morphogenesis GO:0048702 1 0.144
protein localization to plasma membrane GO:0072659 93 0.142
smoothened signaling pathway GO:0007224 14 0.139
digestive system development GO:0055123 75 0.133
cell morphogenesis involved in differentiation GO:0000904 144 0.133
Fly
central nervous system development GO:0007417 123 0.128
digestive tract development GO:0048565 75 0.127
heart development GO:0007507 95 0.126
digestive tract morphogenesis GO:0048546 56 0.125
detection of stimulus GO:0051606 85 0.125
positive regulation of smoothened signaling pathway GO:0045880 4 0.123
ear morphogenesis GO:0042471 7 0.122
embryonic morphogenesis GO:0048598 85 0.121
regulation of protein localization to plasma membrane GO:1903076 40 0.119
cardiac endothelial cell differentiation GO:0003348 2 0.118
forebrain development GO:0030900 26 0.118
positive regulation of developmental process GO:0051094 314 0.117
mitotic cell cycle phase transition GO:0044772 162 0.116
cell growth GO:0016049 160 0.115
membrane organization GO:0061024 292 0.115
epithelial tube morphogenesis GO:0060562 38 0.115
regulation of cell cycle phase transition GO:1901987 126 0.115
amine metabolic process GO:0009308 44 0.115
tissue morphogenesis GO:0048729 96 0.114
regulation of cellular amine metabolic process GO:0033238 11 0.114
muscle structure development GO:0061061 98 0.114
establishment of protein localization to membrane GO:0090150 121 0.111
aorta morphogenesis GO:0035909 1 0.111
regulation of cell cycle g1 s phase transition GO:1902806 42 0.111
negative regulation of cell cycle process GO:0010948 121 0.109
sensory organ morphogenesis GO:0090596 21 0.108
Fly
cell cycle phase transition GO:0044770 173 0.106
single organism membrane organization GO:0044802 268 0.106
response to biotic stimulus GO:0009607 276 0.106
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.103
neural tube development GO:0021915 9 0.103
negative regulation of cell cycle GO:0045786 193 0.101
female gamete generation GO:0007292 2 0.101
Fly
post embryonic development GO:0009791 2 0.100
Fly
segmentation GO:0035282 4 0.100
regulation of cell migration GO:0030334 289 0.100
Fly
head development GO:0060322 108 0.098
telencephalon development GO:0021537 17 0.097
brain development GO:0007420 97 0.096
enzyme linked receptor protein signaling pathway GO:0007167 303 0.096
endothelial cell fate commitment GO:0060839 3 0.094
endothelium development GO:0003158 33 0.092
autonomic nervous system development GO:0048483 1 0.091
ras protein signal transduction GO:0007265 73 0.091
cell adhesion GO:0007155 325 0.090
regulation of cellular ketone metabolic process GO:0010565 50 0.089
embryonic skeletal system development GO:0048706 13 0.089
positive regulation of cell proliferation GO:0008284 301 0.089
response to wounding GO:0009611 168 0.088
muscle cell differentiation GO:0042692 63 0.088
detection of biotic stimulus GO:0009595 21 0.088
neurogenesis GO:0022008 169 0.087
Fly
cell projection morphogenesis GO:0048858 129 0.086
Fly
positive regulation of cell differentiation GO:0045597 211 0.086
regulation of mitotic cell cycle phase transition GO:1901990 118 0.084
cellular component assembly involved in morphogenesis GO:0010927 73 0.084
g1 s transition of mitotic cell cycle GO:0000082 78 0.084
endocrine pancreas development GO:0031018 11 0.084
establishment of protein localization to plasma membrane GO:0090002 68 0.083
cellular amino acid metabolic process GO:0006520 116 0.083
regulation of cell cycle GO:0051726 393 0.083
Fly
wnt signaling pathway GO:0016055 156 0.081
positive regulation of cellular amine metabolic process GO:0033240 7 0.081
axon extension involved in axon guidance GO:0048846 5 0.080
negative regulation of cell proliferation GO:0008285 228 0.080
cartilage development GO:0051216 31 0.079
regulation of cellular amino acid metabolic process GO:0006521 6 0.078
cardiocyte differentiation GO:0035051 23 0.078
cell cycle g1 s phase transition GO:0044843 80 0.077
small gtpase mediated signal transduction GO:0007264 78 0.077
morphogenesis of an epithelium GO:0002009 60 0.077
regulation of cellular component movement GO:0051270 334 0.077
Fly
inner ear development GO:0048839 8 0.077
biological adhesion GO:0022610 331 0.076
neuron development GO:0048666 113 0.076
Fly
negative regulation of cell death GO:0060548 345 0.076
regulation of anatomical structure morphogenesis GO:0022603 286 0.075
cell part morphogenesis GO:0032990 137 0.074
Fly
regulation of cell motility GO:2000145 299 0.074
Fly
embryonic organ morphogenesis GO:0048562 24 0.074
skeletal system morphogenesis GO:0048705 24 0.074
endothelial cell differentiation GO:0045446 26 0.071
cellular response to endogenous stimulus GO:0071495 336 0.069
notch signaling pathway GO:0007219 31 0.067
striated muscle tissue development GO:0014706 59 0.067
positive regulation of phosphorylation GO:0042327 394 0.066
canonical wnt signaling pathway GO:0060070 116 0.066
regulation of cellular component biogenesis GO:0044087 281 0.066
negative regulation of mitotic cell cycle GO:0045930 102 0.066
system process GO:0003008 349 0.066
pancreas development GO:0031016 19 0.066
motor neuron axon guidance GO:0008045 2 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.063
cardiac chamber development GO:0003205 30 0.063
cellular amine metabolic process GO:0044106 41 0.062
muscle tissue development GO:0060537 62 0.061
nucleoside triphosphate metabolic process GO:0009141 422 0.061
negative regulation of protein metabolic process GO:0051248 391 0.060
eye morphogenesis GO:0048592 16 0.060
Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.060
regulation of cell development GO:0060284 161 0.060
locomotory behavior GO:0007626 1 0.059
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.059
embryonic organ development GO:0048568 36 0.059
protein localization to organelle GO:0033365 280 0.058
Fly
embryonic skeletal system morphogenesis GO:0048704 9 0.057
purine ribonucleotide catabolic process GO:0009154 404 0.057
negative regulation of cellular protein metabolic process GO:0032269 353 0.057
multicellular organismal aging GO:0010259 3 0.057
mapk cascade GO:0000165 288 0.057
organelle assembly GO:0070925 176 0.056
determination of adult lifespan GO:0008340 2 0.056
spinal cord development GO:0021510 4 0.055
positive regulation of protein phosphorylation GO:0001934 313 0.054
skeletal system development GO:0001501 79 0.054
actomyosin structure organization GO:0031032 59 0.054
response to oxygen containing compound GO:1901700 369 0.053
negative regulation of programmed cell death GO:0043069 321 0.053
purine containing compound catabolic process GO:0072523 411 0.052
endodermal cell fate commitment GO:0001711 4 0.052
gliogenesis GO:0042063 21 0.052
regulation of mapk cascade GO:0043408 262 0.051
osteoblast proliferation GO:0033687 8 0.051
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.051
skeletal muscle fiber development GO:0048741 12 0.051
cell fate determination GO:0001709 3 0.051
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.051
oligodendrocyte differentiation GO:0048709 7 0.050
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.050
positive regulation of transport GO:0051050 336 0.049
semicircular canal development GO:0060872 1 0.049
negative regulation of gliogenesis GO:0014014 3 0.049
regionalization GO:0003002 29 0.049
muscle organ development GO:0007517 56 0.048
ribonucleoside triphosphate metabolic process GO:0009199 412 0.048
ribonucleotide catabolic process GO:0009261 405 0.047
cellular response to oxygen containing compound GO:1901701 276 0.047
neuron projection morphogenesis GO:0048812 50 0.047
Fly
oogenesis GO:0048477 2 0.047
Fly
neuron projection development GO:0031175 106 0.046
Fly
negative regulation of apoptotic process GO:0043066 316 0.046
regulation of canonical wnt signaling pathway GO:0060828 88 0.046
chemical homeostasis GO:0048878 306 0.046
Fly
developmental growth involved in morphogenesis GO:0060560 23 0.046
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
cardiac ventricle development GO:0003231 23 0.046
regulation of cell growth GO:0001558 135 0.045
reproductive process GO:0022414 106 0.045
Fly
response to growth factor GO:0070848 205 0.044
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.044
nucleotide catabolic process GO:0009166 408 0.044
developmental cell growth GO:0048588 18 0.044
embryonic digestive tract development GO:0048566 10 0.044
eye development GO:0001654 42 0.044
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.044
Fly
nucleoside catabolic process GO:0009164 408 0.044
dorsal ventral pattern formation GO:0009953 15 0.044
nuclear transport GO:0051169 179 0.044
Fly
embryonic epithelial tube formation GO:0001838 4 0.044
axon extension GO:0048675 13 0.044
regulation of intracellular transport GO:0032386 195 0.043
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.043
negative regulation of cell migration GO:0030336 102 0.043
determination of bilateral symmetry GO:0009855 15 0.043
neural tube formation GO:0001841 3 0.043
negative regulation of catalytic activity GO:0043086 335 0.042
stem cell maintenance GO:0019827 19 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.042
cell fate commitment GO:0045165 27 0.042
Fly
sensory organ development GO:0007423 52 0.042
Fly
neurological system process GO:0050877 163 0.042
axonogenesis GO:0007409 31 0.042
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
glycosyl compound catabolic process GO:1901658 413 0.042
endodermal cell fate specification GO:0001714 4 0.041
ameboidal type cell migration GO:0001667 135 0.041
Fly
establishment of protein localization to organelle GO:0072594 172 0.041
Fly
glial cell differentiation GO:0010001 11 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.041
positive regulation of apoptotic process GO:0043065 246 0.041
organ formation GO:0048645 3 0.040
negative regulation of locomotion GO:0040013 118 0.040
cytoplasmic transport GO:0016482 379 0.040
Fly
neuromuscular junction development GO:0007528 3 0.040
cellular response to growth factor stimulus GO:0071363 197 0.040
regulation of growth GO:0040008 165 0.040
regulation of nucleotide metabolic process GO:0006140 269 0.040
nucleoside phosphate catabolic process GO:1901292 412 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
specification of organ identity GO:0010092 3 0.040
striated muscle cell differentiation GO:0051146 43 0.040
immune system development GO:0002520 195 0.040
embryo development GO:0009790 123 0.039
ribonucleoside catabolic process GO:0042454 406 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
positive regulation of cell development GO:0010720 92 0.039
regulation of transferase activity GO:0051338 355 0.039
hemopoiesis GO:0030097 180 0.039
positive regulation of locomotion GO:0040017 186 0.039
cardioblast differentiation GO:0010002 8 0.039
guanosine containing compound catabolic process GO:1901069 239 0.039
positive regulation of programmed cell death GO:0043068 249 0.039
regulation of cellular response to stress GO:0080135 244 0.039
lipid metabolic process GO:0006629 381 0.038
regulation of kinase activity GO:0043549 314 0.038
regulation of protein transport GO:0051223 213 0.038
Fly
response to abiotic stimulus GO:0009628 336 0.038
negative regulation of wnt signaling pathway GO:0030178 69 0.038
hematopoietic or lymphoid organ development GO:0048534 186 0.038
positive regulation of cellular catabolic process GO:0031331 284 0.038
positive regulation of mapk cascade GO:0043410 190 0.038
muscle cell development GO:0055001 29 0.038
epithelium migration GO:0090132 119 0.038
Fly
gtp catabolic process GO:0006184 237 0.038
regulation of notch signaling pathway GO:0008593 18 0.037
heart formation GO:0060914 2 0.037
regulation of cell morphogenesis GO:0022604 153 0.037
generation of neurons GO:0048699 152 0.037
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.037
regulation of nervous system development GO:0051960 88 0.037
anterior posterior axis specification GO:0009948 2 0.036
epithelial cell proliferation GO:0050673 128 0.036
single organism reproductive process GO:0044702 98 0.036
Fly
regulation of cell adhesion GO:0030155 166 0.036
chromatin organization GO:0006325 351 0.036
ion transmembrane transport GO:0034220 338 0.035
endothelial cell migration GO:0043542 86 0.035
single organism cell adhesion GO:0098602 179 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
regulation of wnt signaling pathway GO:0030111 123 0.035
peripheral nervous system development GO:0007422 2 0.035
smooth muscle tissue development GO:0048745 3 0.035
positive regulation of cell motility GO:2000147 177 0.035
regulation of proteolysis GO:0030162 293 0.035
regulation of gtp catabolic process GO:0033124 180 0.034
regulation of protein kinase activity GO:0045859 289 0.034
organophosphate catabolic process GO:0046434 430 0.034
regulation of ras protein signal transduction GO:0046578 155 0.034
guanosine containing compound metabolic process GO:1901068 244 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
cell fate specification GO:0001708 8 0.034
camera type eye development GO:0043010 25 0.033
positive regulation of cell cycle GO:0045787 140 0.033
regulation of neurogenesis GO:0050767 82 0.033
angiogenesis GO:0001525 147 0.033
negative regulation of multicellular organismal process GO:0051241 317 0.033
secretion by cell GO:0032940 226 0.033
secretion GO:0046903 254 0.033
cellular macromolecular complex assembly GO:0034622 324 0.033
aorta development GO:0035904 2 0.033
regulation of locomotion GO:0040012 329 0.032
Fly
neuron projection extension GO:1990138 14 0.032
regulation of axon guidance GO:1902667 3 0.032
negative regulation of protein modification process GO:0031400 200 0.032
neuron projection extension involved in neuron projection guidance GO:1902284 5 0.032
intracellular protein transport GO:0006886 270 0.032
memory GO:0007613 3 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
tissue migration GO:0090130 119 0.032
Fly
regulation of intracellular protein transport GO:0033157 123 0.031
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.031
positive regulation of cell death GO:0010942 263 0.031
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.031
response to lipid GO:0033993 206 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
ear development GO:0043583 14 0.031
dephosphorylation GO:0016311 209 0.031
protein targeting GO:0006605 187 0.030
response to organic cyclic compound GO:0014070 204 0.030
regulation of epithelial cell proliferation GO:0050678 113 0.030
cation transport GO:0006812 331 0.030
axon development GO:0061564 34 0.030
Fly
developmental growth GO:0048589 48 0.030
stem cell division GO:0017145 2 0.030
rho protein signal transduction GO:0007266 26 0.030
regulation of cell projection organization GO:0031344 107 0.029
negative regulation of cellular component movement GO:0051271 106 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
negative regulation of transport GO:0051051 176 0.029
osteoblast differentiation GO:0001649 92 0.029
regulation of gtpase activity GO:0043087 180 0.029
neuroblast proliferation GO:0007405 4 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
regulation of secretion by cell GO:1903530 177 0.029
vesicle mediated transport GO:0016192 371 0.028
Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.028
cytokine production GO:0001816 247 0.028
forebrain generation of neurons GO:0021872 3 0.028
regulation of secretion GO:0051046 194 0.028
protein catabolic process GO:0030163 325 0.028
transmembrane transport GO:0055085 399 0.027
positive regulation of catabolic process GO:0009896 310 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
regulation of smoothened signaling pathway GO:0008589 6 0.027
Fly
negative regulation of phosphorylation GO:0042326 174 0.027
immune response GO:0006955 307 0.027
adult locomotory behavior GO:0008344 1 0.027
regulation of neuron differentiation GO:0045664 70 0.027
defense response GO:0006952 315 0.027
epithelial cell migration GO:0010631 119 0.027
Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.026
protein ubiquitination GO:0016567 314 0.026
apoptotic signaling pathway GO:0097190 268 0.026
negative regulation of cell motility GO:2000146 104 0.026
response to external biotic stimulus GO:0043207 261 0.026
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.026
diencephalon development GO:0021536 6 0.026
response to other organism GO:0051707 261 0.026
regulation of nucleotide catabolic process GO:0030811 205 0.026
myotube cell development GO:0014904 14 0.026
cell division GO:0051301 168 0.026
regulation of nucleoside metabolic process GO:0009118 209 0.026
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.026
negative regulation of protein phosphorylation GO:0001933 140 0.026
positive regulation of cell cycle process GO:0090068 106 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
heart looping GO:0001947 7 0.026
nucleocytoplasmic transport GO:0006913 176 0.026
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.026
positive regulation of protein kinase activity GO:0045860 190 0.025
primary neural tube formation GO:0014020 3 0.025
skeletal muscle organ development GO:0060538 26 0.025
cell cell signaling GO:0007267 155 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
single organismal cell cell adhesion GO:0016337 148 0.025
regulation of actin cytoskeleton organization GO:0032956 116 0.025
regulation of cytoplasmic transport GO:1903649 149 0.025
Fly
positive regulation of immune system process GO:0002684 283 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
positive regulation of protein transport GO:0051222 135 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.025
regulation of peptidase activity GO:0052547 180 0.025
neural crest cell development GO:0014032 3 0.025
cell activation GO:0001775 213 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
somitogenesis GO:0001756 2 0.024
regulation of cytokine production GO:0001817 232 0.024
behavior GO:0007610 112 0.024
metal ion transport GO:0030001 272 0.024
cellular homeostasis GO:0019725 196 0.024
regulation of axon extension involved in axon guidance GO:0048841 2 0.024
cellular lipid metabolic process GO:0044255 303 0.024
muscle cell fate commitment GO:0042693 4 0.024
regulation of dna metabolic process GO:0051052 153 0.024
myeloid cell differentiation GO:0030099 117 0.024
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
cellular metal ion homeostasis GO:0006875 146 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
regulation of ras gtpase activity GO:0032318 128 0.023
lipid biosynthetic process GO:0008610 177 0.023
positive regulation of kinase activity GO:0033674 204 0.023
negative regulation of cell adhesion GO:0007162 64 0.023
specification of symmetry GO:0009799 16 0.023
positive regulation of organelle organization GO:0010638 195 0.023
salivary gland morphogenesis GO:0007435 4 0.023
endochondral bone morphogenesis GO:0060350 3 0.023
regulation of protein complex assembly GO:0043254 147 0.022
regulation of nucleocytoplasmic transport GO:0046822 98 0.022
Fly
protein localization to nucleus GO:0034504 136 0.022
Fly
chromatin modification GO:0016568 298 0.022
positive regulation of transferase activity GO:0051347 227 0.022
axon guidance GO:0007411 12 0.022
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
protein import into nucleus GO:0006606 104 0.022
Fly
cellular response to organic cyclic compound GO:0071407 127 0.021
hindlimb morphogenesis GO:0035137 2 0.021
regulation of homeostatic process GO:0032844 121 0.021
cellular chemical homeostasis GO:0055082 180 0.021
limbic system development GO:0021761 3 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
protein processing GO:0016485 226 0.021
compound eye development GO:0048749 1 0.021
determination of left right symmetry GO:0007368 11 0.021
positive regulation of protein localization to plasma membrane GO:1903078 20 0.021
positive regulation of gtpase activity GO:0043547 166 0.021
tube closure GO:0060606 3 0.021
cellular response to lipid GO:0071396 127 0.020
cation transmembrane transport GO:0098655 238 0.020
glial cell migration GO:0008347 4 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
lung alveolus development GO:0048286 4 0.020
morphogenesis of a polarized epithelium GO:0001738 3 0.020
response to axon injury GO:0048678 1 0.020
regulation of angiogenesis GO:0045765 92 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
cell type specific apoptotic process GO:0097285 125 0.020
oocyte differentiation GO:0009994 2 0.020
regulation of multi organism process GO:0043900 157 0.020
cellular protein complex assembly GO:0043623 188 0.020
response to cytokine GO:0034097 232 0.020
regulation of reactive oxygen species metabolic process GO:2000377 41 0.020
protein targeting to nucleus GO:0044744 104 0.020
Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
response to hormone GO:0009725 175 0.020
pattern specification process GO:0007389 43 0.020
protein maturation GO:0051604 233 0.020
mesenchymal cell development GO:0014031 50 0.020
immune effector process GO:0002252 159 0.020
mesodermal cell fate commitment GO:0001710 2 0.020
leukocyte activation GO:0045321 164 0.020
metal ion homeostasis GO:0055065 169 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
negative regulation of cell development GO:0010721 48 0.020

PTCH1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.026
Human
disease of cellular proliferation DOID:14566 174 0.026
Human
organ system cancer DOID:0050686 164 0.026
Human
disease of metabolism DOID:0014667 295 0.024
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
central nervous system disease DOID:331 186 0.023
inherited metabolic disorder DOID:655 242 0.022