|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.895
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.869
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.826
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.801
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.801
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.799
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.788
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.740
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.738
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.732
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.693
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.676
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.620
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.608
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.571
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.547
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.534
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.515
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.481
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.474
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.467
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.450
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.432
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.419
|
Human Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.412
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.392
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.383
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.378
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.376
|
Human Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.351
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.341
|
Human Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.323
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.313
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.292
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.291
|
Human |
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.285
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.273
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.264
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.264
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.262
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.258
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.257
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.255
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.249
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.245
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.244
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.242
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.233
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.232
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.228
|
|
|
|
memory
|
GO:0007613 |
3 |
0.221
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.210
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.207
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.207
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.202
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.198
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.197
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.191
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.191
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.190
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.188
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.183
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.181
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.169
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.167
|
Human Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.162
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.160
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.160
|
|
|
|
system process
|
GO:0003008 |
349 |
0.153
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.147
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.146
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.143
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.140
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.138
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.138
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.137
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.137
|
Human Mouse |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.135
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.135
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.133
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.133
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.132
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.130
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.130
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.129
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.125
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.123
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.122
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.121
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.120
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.120
|
Human Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.119
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.119
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.118
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.117
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.117
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.116
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.113
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.112
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.111
|
|
|
|
myeloid dendritic cell chemotaxis
|
GO:0002408 |
3 |
0.109
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.108
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.107
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.106
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.105
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.105
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.102
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.101
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.100
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.100
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.099
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.098
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.098
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.098
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.097
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.097
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.097
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.095
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.095
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.095
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.095
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.094
|
Mouse |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.094
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.093
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.093
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.091
|
|
|
|
regulation of astrocyte chemotaxis
|
GO:2000458 |
1 |
0.091
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.090
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.089
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.089
|
Human |
|
|
response to radiation
|
GO:0009314 |
151 |
0.088
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.088
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.087
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.087
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.087
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.083
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.083
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.082
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.082
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.082
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.081
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.080
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.079
|
|
|
|
learning
|
GO:0007612 |
11 |
0.079
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.078
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.078
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.075
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.075
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.075
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.075
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.071
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.069
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.068
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.067
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.067
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.066
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.065
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.065
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.065
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.064
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.064
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.061
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.060
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.059
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.059
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.058
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.058
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.057
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.057
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.053
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.053
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.053
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.052
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.052
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.052
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.052
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.052
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.052
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.050
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.050
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.050
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.050
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.049
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
65 |
0.049
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.049
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.049
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.049
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.048
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.048
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.048
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.048
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.047
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.046
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.046
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.046
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.046
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.046
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.046
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.045
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.045
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.045
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.045
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.045
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.045
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.045
|
|
|
|
chemokine c c motif ligand 19 signaling pathway
|
GO:0038115 |
1 |
0.044
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.044
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.044
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.044
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.044
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.043
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.043
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.043
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.043
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.043
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.043
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.042
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.042
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.042
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.042
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.042
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.041
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.041
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.041
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.040
|
|
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.040
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.040
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.040
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.040
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.040
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.039
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.039
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.039
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.038
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.038
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.037
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.037
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.037
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.037
|
Mouse |
|
|
cation transport
|
GO:0006812 |
331 |
0.037
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.037
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.037
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.037
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.037
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.036
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.036
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.036
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.036
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.036
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.036
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.035
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.035
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.035
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.035
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.035
|
Human |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.035
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.035
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.034
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.034
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.034
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.034
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.033
|
Mouse |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.033
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.033
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.033
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.032
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.032
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.032
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.032
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.031
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.031
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.031
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.031
|
|
|
|
positive regulation of astrocyte chemotaxis
|
GO:2000464 |
1 |
0.031
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.031
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.031
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.030
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.030
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.030
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.030
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.030
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.030
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.030
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.030
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.030
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.029
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.029
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.029
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.029
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.029
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.029
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.029
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.029
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.029
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.029
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.029
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.029
|
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.028
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.028
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.028
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.028
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.028
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.028
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.028
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.028
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.028
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.027
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.027
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.027
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.027
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.027
|
Human |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.027
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.026
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.026
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.026
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.026
|
Mouse |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.026
|
|
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.026
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.026
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.026
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.026
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.026
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.026
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.026
|
|
|
|
astrocyte chemotaxis
|
GO:0035700 |
1 |
0.025
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.025
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.025
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.025
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.025
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.025
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.025
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.025
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.025
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.025
|
Mouse |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.025
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.024
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.024
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.024
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.024
|
Mouse |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.024
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.024
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.024
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.024
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.024
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.024
|
Human Mouse |
|
|
negative regulation of receptor activity
|
GO:2000272 |
15 |
0.024
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.024
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.024
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.023
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.023
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.023
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.023
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.023
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.023
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.023
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.023
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
Human |
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.023
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.023
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.023
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.023
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.023
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.023
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.022
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.022
|
|
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.022
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.022
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.022
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.022
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.022
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.022
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.022
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.022
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.022
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.022
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.022
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.022
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.022
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.022
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.022
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.021
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.021
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.021
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.021
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.021
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.021
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.021
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
13 |
0.021
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.021
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.021
|
Mouse |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.021
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.021
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.020
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.020
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.020
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.020
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.020
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.020
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.020
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.020
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.020
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.020
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.020
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.020
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.019
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.019
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.019
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.019
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.019
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.019
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.019
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.019
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.019
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.019
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.019
|
Human |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.019
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.019
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.019
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.019
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.019
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.019
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.018
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.018
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.018
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.018
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.018
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.018
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.018
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.018
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.018
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.018
|
Mouse |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.018
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.018
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.018
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.018
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.018
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.018
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.017
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.017
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.017
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.017
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.017
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.017
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.017
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.017
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.017
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.017
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.017
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.017
|
Human Mouse |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.017
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.017
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.017
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.017
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.017
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.017
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.017
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.016
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.016
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.016
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.016
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.016
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.016
|
Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.016
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.016
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.016
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.016
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.016
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.016
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.016
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.016
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.016
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.016
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.016
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.016
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.016
|
|
