|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.978
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.906
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.898
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.881
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.851
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.822
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.773
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.712
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.681
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.663
|
|
|
|
negative regulation of sequestering of calcium ion
|
GO:0051283 |
41 |
0.619
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.606
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.599
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.562
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
7 |
0.528
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.480
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.478
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.450
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
4 |
0.444
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.441
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.439
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.427
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.423
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.411
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.409
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.404
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.371
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.365
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.344
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.344
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.344
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.338
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.321
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.317
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.292
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
3 |
0.289
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.278
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.270
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.269
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.267
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.265
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.261
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.257
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.256
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.254
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.251
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.244
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.242
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.237
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.236
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.235
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.231
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.227
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.221
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.221
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.214
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.207
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.204
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.199
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
1 |
0.186
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.184
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.183
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.181
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.178
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.171
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.168
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.168
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.167
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
5 |
0.166
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.165
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.164
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.162
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.161
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.160
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.153
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.152
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.151
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
1 |
0.148
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.147
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.146
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.145
|
|
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.143
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.143
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.141
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.141
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.138
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.137
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.137
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.135
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.132
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.123
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.122
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.121
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.117
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.116
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.116
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.115
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.114
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.112
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.111
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.109
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.108
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.108
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.107
|
|
|
|
positive regulation of calcium ion transport into cytosol
|
GO:0010524 |
20 |
0.107
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.107
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.106
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.106
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
8 |
0.101
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.100
|
|
|
|
drinking behavior
|
GO:0042756 |
1 |
0.100
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.096
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.095
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.095
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.094
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.093
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.093
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.092
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.092
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
7 |
0.091
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.091
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.091
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.090
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.090
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.090
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.089
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.087
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.086
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.085
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.085
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.083
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.081
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.079
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.076
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.076
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.076
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.075
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.074
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.074
|
|
|
|
positive regulation of release of sequestered calcium ion into cytosol
|
GO:0051281 |
16 |
0.074
|
|
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.074
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.074
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.074
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.072
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.072
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.072
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.071
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.071
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.070
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.069
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.069
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.068
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.068
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.068
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.068
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.067
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.067
|
|
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.066
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.066
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.065
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.065
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.065
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.065
|
|
|
|
immunoglobulin biosynthetic process
|
GO:0002378 |
2 |
0.064
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.064
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.064
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.063
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.063
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.063
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.062
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.062
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.062
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.062
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.062
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.061
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.060
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.060
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.059
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.059
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.059
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.058
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.058
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.058
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.058
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.058
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.058
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.058
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.057
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.057
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.057
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.057
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.057
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.056
|
|
|
|
positive regulation of endothelial cell development
|
GO:1901552 |
1 |
0.056
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.056
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.055
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.055
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.055
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.055
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.055
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.054
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.054
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.054
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.054
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.053
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.053
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.053
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.053
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.052
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.052
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.052
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.052
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.051
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.051
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.051
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.051
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.050
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.050
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.050
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.049
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.049
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.049
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.049
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.048
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.048
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.048
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.048
|
|
|
|
isotype switching
|
GO:0045190 |
3 |
0.047
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.047
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.047
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.047
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.046
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.046
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.046
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.046
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.046
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.046
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.046
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.046
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.045
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.045
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.045
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.045
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.044
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.044
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.044
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.044
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.043
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.043
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.043
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.043
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.042
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.042
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.042
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.041
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.041
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.041
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.041
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.041
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.041
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.041
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
10 |
0.040
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.040
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.040
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.040
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.040
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.039
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.039
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.039
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.039
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.039
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.039
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.039
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.039
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.039
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.039
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.039
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.038
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.038
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.038
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.037
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
3 |
0.037
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.037
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.037
|
|
|
|
positive regulation of collateral sprouting
|
GO:0048672 |
2 |
0.037
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.036
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.036
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.036
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.036
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.036
|
|
|
|
regulation of alkaline phosphatase activity
|
GO:0010692 |
2 |
0.036
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.036
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.036
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.035
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.035
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.035
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.035
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.035
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.035
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.035
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.035
|
|
|
|
cellular defense response
|
GO:0006968 |
2 |
0.035
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.034
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.034
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.034
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.034
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.034
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.034
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.034
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.034
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.034
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.034
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.034
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.033
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.033
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.033
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.033
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.033
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.033
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.033
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.033
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.032
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.032
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.032
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.032
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.031
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.031
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.031
|
|
|
|
cannabinoid signaling pathway
|
GO:0038171 |
2 |
0.031
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.031
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.031
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.031
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.031
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.030
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.030
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.030
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.030
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.030
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.030
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.030
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.030
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.030
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.029
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.029
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.029
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.029
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.029
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.029
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.029
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.029
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.028
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.028
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.028
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.028
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.028
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.028
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.028
|
|
|
|
growth
|
GO:0040007 |
202 |
0.027
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.027
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.027
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.027
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.027
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.027
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.027
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.027
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.027
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.026
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.026
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.026
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.026
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.026
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.026
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
24 |
0.026
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.026
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.026
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.025
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.025
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.025
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.025
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.025
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.025
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.025
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.025
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.025
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.024
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.024
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
10 |
0.024
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.024
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.024
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.024
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.024
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.024
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.024
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.024
|
|
|
|
platelet formation
|
GO:0030220 |
4 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.024
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.023
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.023
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.023
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.023
|
|
|
|
memory
|
GO:0007613 |
3 |
0.023
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.023
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.022
|
|
|
|
bone marrow development
|
GO:0048539 |
3 |
0.022
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.022
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.022
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.022
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.022
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.022
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.022
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.022
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.022
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.022
|
|
|
|
system process
|
GO:0003008 |
349 |
0.022
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.021
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.021
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.021
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.021
|
|
|
|
regulation of gamma delta t cell activation involved in immune response
|
GO:2001191 |
1 |
0.021
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.021
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.021
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.021
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.021
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.021
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.021
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.021
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.020
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.020
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.020
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
18 |
0.020
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.020
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.020
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.020
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.020
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.020
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.020
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.020
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.020
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.020
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.019
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.019
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.019
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.019
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.019
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
|
|
|
regulation of cell killing
|
GO:0031341 |
22 |
0.019
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
14 |
0.019
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.019
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
3 |
0.019
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.019
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.019
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.019
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.019
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.019
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.019
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.019
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.019
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.019
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.019
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.018
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.018
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.018
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.018
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.018
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.018
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.018
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.018
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
1 |
0.018
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.018
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
19 |
0.018
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.018
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.018
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.018
|
|
