Homo sapiens

18 known processes

TUFM

Tu translation elongation factor, mitochondrial

(Aliases: COXPD4,P43,EF-TuMT,EFTU)

TUFM biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.976
Worm
ribonucleoside monophosphate metabolic process GO:0009161 187 0.749
purine nucleoside monophosphate metabolic process GO:0009126 186 0.673
receptor mediated endocytosis GO:0006898 84 0.661
atp metabolic process GO:0046034 176 0.599
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.448
translation GO:0006412 132 0.416
vesicle mediated transport GO:0016192 371 0.414
ribose phosphate biosynthetic process GO:0046390 82 0.327
purine containing compound biosynthetic process GO:0072522 88 0.322
multicellular organismal aging GO:0010259 3 0.316
Worm
ribonucleoside triphosphate metabolic process GO:0009199 412 0.271
nucleoside triphosphate metabolic process GO:0009141 422 0.267
cellular macromolecular complex assembly GO:0034622 324 0.255
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.246
cellular amino acid metabolic process GO:0006520 116 0.245
excretion GO:0007588 9 0.241
purine nucleoside triphosphate metabolic process GO:0009144 412 0.233
negative regulation of cell proliferation GO:0008285 228 0.222
determination of adult lifespan GO:0008340 2 0.216
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.210
oxidation reduction process GO:0055114 396 0.197
regulation of purine nucleotide metabolic process GO:1900542 264 0.194
nucleoside monophosphate metabolic process GO:0009123 191 0.183
nucleotide biosynthetic process GO:0009165 109 0.174
protein oligomerization GO:0051259 173 0.173
embryo development GO:0009790 123 0.172
Worm
embryo development ending in birth or egg hatching GO:0009792 34 0.148
Worm
mitochondrion organization GO:0007005 156 0.148
regulation of oxidative phosphorylation GO:0002082 3 0.146
endocytosis GO:0006897 159 0.135
cellular protein complex assembly GO:0043623 188 0.131
female gamete generation GO:0007292 2 0.128
cytoplasmic transport GO:0016482 379 0.108
cellular component morphogenesis GO:0032989 314 0.105
cellular macromolecule catabolic process GO:0044265 380 0.104
aging GO:0007568 66 0.103
Worm
organophosphate biosynthetic process GO:0090407 163 0.102
oogenesis GO:0048477 2 0.100
purine ribonucleotide biosynthetic process GO:0009152 79 0.100
sex differentiation GO:0007548 45 0.097
cell development GO:0048468 328 0.093
mitochondrial rna metabolic process GO:0000959 15 0.091
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.082
generation of precursor metabolites and energy GO:0006091 68 0.080
ribonucleotide biosynthetic process GO:0009260 81 0.079
positive regulation of organelle organization GO:0010638 195 0.069
system process GO:0003008 349 0.068
negative regulation of multicellular organismal process GO:0051241 317 0.067
hematopoietic or lymphoid organ development GO:0048534 186 0.063
anion transmembrane transport GO:0098656 76 0.063
regulation of multicellular organism growth GO:0040014 8 0.062
regulation of nucleoside metabolic process GO:0009118 209 0.060
ossification GO:0001503 121 0.059
positive regulation of multicellular organism growth GO:0040018 6 0.054
positive regulation of apoptotic process GO:0043065 246 0.052
carbohydrate derivative biosynthetic process GO:1901137 207 0.052
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
oxidative phosphorylation GO:0006119 10 0.050
regulation of growth GO:0040008 165 0.049
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.049
purine nucleotide biosynthetic process GO:0006164 84 0.048
cation transmembrane transport GO:0098655 238 0.048
growth GO:0040007 202 0.047
positive regulation of developmental process GO:0051094 314 0.046
transmembrane transport GO:0055085 399 0.046
intracellular protein transport GO:0006886 270 0.043
reproduction GO:0000003 63 0.043
Worm
tissue morphogenesis GO:0048729 96 0.042
protein targeting GO:0006605 187 0.041
developmental process involved in reproduction GO:0003006 66 0.041
regulation of behavior GO:0050795 82 0.040
behavior GO:0007610 112 0.040
endoplasmic reticulum unfolded protein response GO:0030968 16 0.039
ncrna metabolic process GO:0034660 108 0.039
response to abiotic stimulus GO:0009628 336 0.038
positive regulation of cellular component organization GO:0051130 376 0.036
cellular respiration GO:0045333 21 0.036
single organism reproductive process GO:0044702 98 0.036
fatty acid metabolic process GO:0006631 115 0.035
microtubule based process GO:0007017 210 0.035
glycosyl compound biosynthetic process GO:1901659 27 0.035
response to oxygen containing compound GO:1901700 369 0.035
protein maturation GO:0051604 233 0.034
reproductive system development GO:0061458 56 0.034
secretion GO:0046903 254 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
energy derivation by oxidation of organic compounds GO:0015980 43 0.034
single organism cellular localization GO:1902580 332 0.032
organelle assembly GO:0070925 176 0.032
negative regulation of developmental process GO:0051093 247 0.031
regulation of kinase activity GO:0043549 314 0.031
reproductive process GO:0022414 106 0.030
single organism membrane organization GO:0044802 268 0.030
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.030
osteoblast differentiation GO:0001649 92 0.030
nucleoside phosphate biosynthetic process GO:1901293 109 0.030
isocitrate metabolic process GO:0006102 1 0.029
actin filament based process GO:0030029 224 0.029
cell adhesion GO:0007155 325 0.029
protein localization to organelle GO:0033365 280 0.029
response to endoplasmic reticulum stress GO:0034976 49 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
cellular amine metabolic process GO:0044106 41 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
regulation of atp metabolic process GO:1903578 29 0.027
positive regulation of cell death GO:0010942 263 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
regulation of lipid metabolic process GO:0019216 96 0.026
reproductive structure development GO:0048608 55 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
epithelial cell proliferation GO:0050673 128 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
regulation of epithelial cell proliferation GO:0050678 113 0.025
maintenance of location GO:0051235 112 0.024
er nucleus signaling pathway GO:0006984 23 0.023
regulation of developmental growth GO:0048638 30 0.023
ribosome biogenesis GO:0042254 48 0.023
digestive system development GO:0055123 75 0.023
gonad development GO:0008406 34 0.023
response to hormone GO:0009725 175 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
positive regulation of growth GO:0045927 58 0.022
ion transmembrane transport GO:0034220 338 0.022
positive regulation of proteolysis GO:0045862 142 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
regulation of transferase activity GO:0051338 355 0.021
regulation of cell cycle process GO:0010564 266 0.021
regulation of feeding behavior GO:0060259 3 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
protein acetylation GO:0006473 116 0.020
secretion by cell GO:0032940 226 0.020
mitochondrion morphogenesis GO:0070584 8 0.020
ribonucleoprotein complex subunit organization GO:0071826 81 0.020
tube morphogenesis GO:0035239 95 0.019
purine ribonucleoside biosynthetic process GO:0046129 23 0.019
regulation of dna metabolic process GO:0051052 153 0.019
nucleotide catabolic process GO:0009166 408 0.018
response to cytokine GO:0034097 232 0.018
development of primary sexual characteristics GO:0045137 35 0.018
nucleoside catabolic process GO:0009164 408 0.018
phosphate ion transmembrane transport GO:0035435 4 0.018
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.018
multicellular organismal reproductive process GO:0048609 40 0.018
chromatin organization GO:0006325 351 0.018
neuromuscular junction development GO:0007528 3 0.017
gland development GO:0048732 48 0.017
response to topologically incorrect protein GO:0035966 29 0.017
cellular response to topologically incorrect protein GO:0035967 19 0.017
organic anion transport GO:0015711 103 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
regulation of cell development GO:0060284 161 0.016
histone modification GO:0016570 251 0.016
dicarboxylic acid metabolic process GO:0043648 29 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
regulation of proteolysis GO:0030162 293 0.015
dna integrity checkpoint GO:0031570 71 0.015
actomyosin structure organization GO:0031032 59 0.015
negative regulation of cell cycle GO:0045786 193 0.015
sulfate transmembrane transport GO:1902358 3 0.015
response to peptide GO:1901652 65 0.015
negative regulation of epithelial cell proliferation GO:0050680 48 0.014
cation homeostasis GO:0055080 189 0.014
rna processing GO:0006396 255 0.014
protein acylation GO:0043543 138 0.014
cell part morphogenesis GO:0032990 137 0.014
cytokine production GO:0001816 247 0.014
cellular ketone metabolic process GO:0042180 80 0.014
immune response GO:0006955 307 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
cofactor metabolic process GO:0051186 87 0.014
protein processing GO:0016485 226 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
negative regulation of organelle organization GO:0010639 126 0.014
response to hypoxia GO:0001666 96 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
neurogenesis GO:0022008 169 0.013
myosin filament assembly GO:0031034 2 0.013
mammary gland morphogenesis GO:0060443 2 0.013
cellular homeostasis GO:0019725 196 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
amine metabolic process GO:0009308 44 0.013
response to organonitrogen compound GO:0010243 156 0.013
organophosphate catabolic process GO:0046434 430 0.013
lymphocyte activation GO:0046649 133 0.013
cellular chemical homeostasis GO:0055082 180 0.013
lipid localization GO:0010876 106 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
positive regulation of dna metabolic process GO:0051054 73 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
internal protein amino acid acetylation GO:0006475 101 0.012
atp catabolic process GO:0006200 157 0.012
cellular lipid metabolic process GO:0044255 303 0.012
morphogenesis of a branching structure GO:0001763 21 0.012
apoptotic signaling pathway GO:0097190 268 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
protein autophosphorylation GO:0046777 123 0.012
positive regulation of spindle checkpoint GO:0090232 7 0.012
biological adhesion GO:0022610 331 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
actin cytoskeleton organization GO:0030036 207 0.012
cell activation GO:0001775 213 0.011
negative regulation of catabolic process GO:0009895 104 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
angiogenesis GO:0001525 147 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
immune system development GO:0002520 195 0.011
regulation of peptidase activity GO:0052547 180 0.011
regulation of cell differentiation GO:0045595 393 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
regulation of gtpase activity GO:0043087 180 0.011
cell cycle checkpoint GO:0000075 117 0.011
regulation of cell cycle GO:0051726 393 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
developmental growth GO:0048589 48 0.011
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.011
embryonic morphogenesis GO:0048598 85 0.011
muscle cell differentiation GO:0042692 63 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
lipid metabolic process GO:0006629 381 0.010
inorganic anion transmembrane transport GO:0098661 47 0.010

TUFM disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.365
inherited metabolic disorder DOID:655 242 0.252
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
carbohydrate metabolic disorder DOID:2978 55 0.012