Homo sapiens

49 known processes

TWF1

twinfilin, actin-binding protein, homolog 1 (Drosophila)

(Aliases: PTK9,MGC23788,MGC41876,A6)

TWF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oogenesis GO:0048477 2 0.129
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.109
vesicle mediated transport GO:0016192 371 0.108
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.105
post embryonic development GO:0009791 2 0.099
regulation of nucleotide metabolic process GO:0006140 269 0.092
glycosyl compound catabolic process GO:1901658 413 0.087
oocyte development GO:0048599 1 0.086
purine nucleoside catabolic process GO:0006152 398 0.084
regulation of cell projection organization GO:0031344 107 0.080
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.079
membrane organization GO:0061024 292 0.076
positive regulation of cellular component organization GO:0051130 376 0.075
negative regulation of phosphate metabolic process GO:0045936 267 0.072
negative regulation of hydrolase activity GO:0051346 182 0.069
nucleoside phosphate catabolic process GO:1901292 412 0.069
cellular component morphogenesis GO:0032989 314 0.066
purine containing compound catabolic process GO:0072523 411 0.065
positive regulation of transport GO:0051050 336 0.065
purine nucleotide catabolic process GO:0006195 405 0.062
cell projection organization GO:0030030 252 0.061
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.060
negative regulation of catalytic activity GO:0043086 335 0.060
ribonucleoside triphosphate catabolic process GO:0009203 391 0.058
segmentation GO:0035282 4 0.056
cell adhesion GO:0007155 325 0.056
guanosine containing compound catabolic process GO:1901069 239 0.055
purine ribonucleotide catabolic process GO:0009154 404 0.054
positive regulation of cell death GO:0010942 263 0.052
cellular macromolecular complex assembly GO:0034622 324 0.052
Yeast Mouse Fly
immune response GO:0006955 307 0.051
organophosphate catabolic process GO:0046434 430 0.051
nervous system development GO:0007399 293 0.051
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
actin cytoskeleton organization GO:0030036 207 0.050
protein catabolic process GO:0030163 325 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.049
anterior posterior axis specification GO:0009948 2 0.049
golgi ribbon formation GO:0090161 3 0.049
female gamete generation GO:0007292 2 0.048
Fly
regulation of gtp catabolic process GO:0033124 180 0.047
negative regulation of catabolic process GO:0009895 104 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.047
protein targeting GO:0006605 187 0.047
regulation of cellular component size GO:0032535 82 0.047
Yeast Mouse Fly
single organism cellular localization GO:1902580 332 0.046
nucleoside triphosphate catabolic process GO:0009143 394 0.046
nucleotide catabolic process GO:0009166 408 0.045
anatomical structure formation involved in morphogenesis GO:0048646 284 0.045
cell morphogenesis GO:0000902 296 0.045
cation transport GO:0006812 331 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.043
amine metabolic process GO:0009308 44 0.043
ribonucleotide catabolic process GO:0009261 405 0.043
positive regulation of developmental process GO:0051094 314 0.042
cellular ion homeostasis GO:0006873 168 0.042
cell cycle phase transition GO:0044770 173 0.041
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
regulation of cellular response to stress GO:0080135 244 0.040
regulation of mitotic cell cycle phase transition GO:1901990 118 0.040
regulation of secretion by cell GO:1903530 177 0.039
secretion by cell GO:0032940 226 0.039
nitrogen compound transport GO:0071705 191 0.039
cellular protein complex assembly GO:0043623 188 0.039
Yeast Mouse Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.039
regulation of mapk cascade GO:0043408 262 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.038
cellular amine metabolic process GO:0044106 41 0.037
reproductive process GO:0022414 106 0.037
Fly
intracellular protein transport GO:0006886 270 0.036
cellular ketone metabolic process GO:0042180 80 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
cellular amino acid metabolic process GO:0006520 116 0.036
oocyte differentiation GO:0009994 2 0.036
response to abiotic stimulus GO:0009628 336 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.035
cell activation GO:0001775 213 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
regulation of cytoskeleton organization GO:0051493 177 0.035
epithelium development GO:0060429 227 0.034
Fly
actin filament based process GO:0030029 224 0.034
chemical homeostasis GO:0048878 306 0.034
locomotory behavior GO:0007626 1 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
regulation of hormone levels GO:0010817 125 0.034
cytokine production GO:0001816 247 0.034
biological adhesion GO:0022610 331 0.034
metal ion transport GO:0030001 272 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
regulation of protein localization GO:0032880 296 0.033
regulation of cell cycle GO:0051726 393 0.033
cellular cation homeostasis GO:0030003 163 0.033
blastoderm segmentation GO:0007350 2 0.032
regulation of cellular component biogenesis GO:0044087 281 0.031
Yeast Mouse Fly
negative regulation of nucleotide catabolic process GO:0030812 16 0.030
regulation of transferase activity GO:0051338 355 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
positive regulation of transferase activity GO:0051347 227 0.030
organ morphogenesis GO:0009887 147 0.030
Fly
cell development GO:0048468 328 0.029
Fly
regulation of secretion GO:0051046 194 0.029
mitotic cell cycle GO:0000278 326 0.029
protein localization to membrane GO:0072657 160 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
negative regulation of multicellular organismal process GO:0051241 317 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.029
neural tube formation GO:0001841 3 0.028
growth GO:0040007 202 0.028
embryonic epithelial tube formation GO:0001838 4 0.028
regulation of vesicle mediated transport GO:0060627 130 0.028
regulation of actin filament based process GO:0032970 141 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
cellular chemical homeostasis GO:0055082 180 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
regulation of anatomical structure size GO:0090066 101 0.027
Yeast Mouse Fly
maintenance of location GO:0051235 112 0.026
Yeast Mouse
gtp metabolic process GO:0046039 239 0.026
anterior posterior axis specification embryo GO:0008595 2 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
immune system development GO:0002520 195 0.025
cellular protein catabolic process GO:0044257 261 0.025
regulation of cell differentiation GO:0045595 393 0.025
mapk cascade GO:0000165 288 0.025
nucleoside catabolic process GO:0009164 408 0.025
regulation of protein complex assembly GO:0043254 147 0.025
Yeast Mouse Fly
secretion GO:0046903 254 0.025
cilium assembly GO:0042384 63 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
cell projection assembly GO:0030031 126 0.024
Fly
nucleoside monophosphate catabolic process GO:0009125 159 0.024
cytoplasmic transport GO:0016482 379 0.024
protein maturation GO:0051604 233 0.023
gtp catabolic process GO:0006184 237 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
negative regulation of protein maturation GO:1903318 142 0.023
mitochondrion distribution GO:0048311 3 0.023
multicellular organismal aging GO:0010259 3 0.023
positive regulation of organelle organization GO:0010638 195 0.023
regulation of growth GO:0040008 165 0.023
ion homeostasis GO:0050801 230 0.023
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
determination of adult lifespan GO:0008340 2 0.022
cell part morphogenesis GO:0032990 137 0.022
regulation of cell migration GO:0030334 289 0.022
tripartite regional subdivision GO:0007351 2 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
positive regulation of protein kinase activity GO:0045860 190 0.022
regulation of multi organism process GO:0043900 157 0.022
regulation of proteolysis GO:0030162 293 0.022
viral process GO:0016032 146 0.022
interspecies interaction between organisms GO:0044419 156 0.022
regulation of response to external stimulus GO:0032101 222 0.022
response to light stimulus GO:0009416 87 0.022
response to cytokine GO:0034097 232 0.022
cellular homeostasis GO:0019725 196 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
negative regulation of cellular catabolic process GO:0031330 83 0.021
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
cation homeostasis GO:0055080 189 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
cellular divalent inorganic cation homeostasis GO:0072503 128 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
regulation of cell cycle phase transition GO:1901987 126 0.021
apoptotic signaling pathway GO:0097190 268 0.021
protein processing GO:0016485 226 0.021
establishment of protein localization to membrane GO:0090150 121 0.020
regulation of immune response GO:0050776 201 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
positive regulation of locomotion GO:0040017 186 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
ras protein signal transduction GO:0007265 73 0.020
regulation of hormone secretion GO:0046883 57 0.020
g protein coupled receptor signaling pathway GO:0007186 207 0.020
positive regulation of keratinocyte migration GO:0051549 4 0.020
response to nitrogen compound GO:1901698 184 0.020
regulation of cell motility GO:2000145 299 0.020
positive regulation of cytokine production GO:0001819 167 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
neuron development GO:0048666 113 0.020
cellular response to oxygen containing compound GO:1901701 276 0.019
positive regulation of kinase activity GO:0033674 204 0.019
regulation of kinase activity GO:0043549 314 0.019
atp catabolic process GO:0006200 157 0.019
cation transmembrane transport GO:0098655 238 0.019
rna processing GO:0006396 255 0.019
endocytosis GO:0006897 159 0.019
Fly
canonical wnt signaling pathway GO:0060070 116 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
regulation of apoptotic signaling pathway GO:2001233 175 0.019
regulation of protein kinase activity GO:0045859 289 0.019
system process GO:0003008 349 0.019
positive regulation of mapk cascade GO:0043410 190 0.019
neurogenesis GO:0022008 169 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of cell development GO:0060284 161 0.018
receptor internalization GO:0031623 43 0.018
viral life cycle GO:0019058 132 0.018
cellular calcium ion homeostasis GO:0006874 117 0.018
rho protein signal transduction GO:0007266 26 0.018
regulation of locomotion GO:0040012 329 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
vacuolar transport GO:0007034 34 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
regulation of cell cycle process GO:0010564 266 0.018
dephosphorylation GO:0016311 209 0.018
atp metabolic process GO:0046034 176 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
endosomal transport GO:0016197 129 0.017
plasma membrane organization GO:0007009 115 0.017
mitotic cell cycle process GO:1903047 286 0.017
regulation of mononuclear cell proliferation GO:0032944 65 0.017
stress activated protein kinase signaling cascade GO:0031098 94 0.017
negative regulation of immune system process GO:0002683 136 0.017
t cell activation GO:0042110 99 0.017
tube closure GO:0060606 3 0.017
somitogenesis GO:0001756 2 0.017
regulation of cytokine production GO:0001817 232 0.017
cell growth GO:0016049 160 0.017
cell cycle checkpoint GO:0000075 117 0.017
establishment of protein localization to plasma membrane GO:0090002 68 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
protein modification by small protein conjugation GO:0032446 342 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of exocytosis GO:0017157 46 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
regulation of neuron projection development GO:0010975 57 0.016
positive regulation of cell motility GO:2000147 177 0.016
regulation of cell projection assembly GO:0060491 47 0.016
Fly
nuclear division GO:0000280 128 0.016
single organism membrane organization GO:0044802 268 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
positive regulation of immune system process GO:0002684 283 0.016
receptor metabolic process GO:0043112 81 0.016
negative regulation of transport GO:0051051 176 0.016
signal release GO:0023061 70 0.016
taxis GO:0042330 157 0.016
multi organism cellular process GO:0044764 156 0.016
neuromuscular junction development GO:0007528 3 0.016
hemopoiesis GO:0030097 180 0.015
spermatid development GO:0007286 4 0.015
mitochondrion organization GO:0007005 156 0.015
protein localization to organelle GO:0033365 280 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
regeneration GO:0031099 4 0.015
response to biotic stimulus GO:0009607 276 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
receptor mediated endocytosis GO:0006898 84 0.015
peripheral nervous system development GO:0007422 2 0.015
metal ion homeostasis GO:0055065 169 0.015
regulation of cellular component movement GO:0051270 334 0.015
innate immune response GO:0045087 178 0.015
regulation of gtpase activity GO:0043087 180 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
circulatory system development GO:0072359 262 0.015
neural tube closure GO:0001843 3 0.015
defense response GO:0006952 315 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
stress activated mapk cascade GO:0051403 93 0.015
regulation of neurogenesis GO:0050767 82 0.014
negative regulation of cell death GO:0060548 345 0.014
golgi vesicle transport GO:0048193 80 0.014
cell fate determination GO:0001709 3 0.014
regulation of camp biosynthetic process GO:0030817 45 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
associative learning GO:0008306 1 0.014
primary neural tube formation GO:0014020 3 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
positive regulation of cellular component movement GO:0051272 181 0.014
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
activation of immune response GO:0002253 114 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
response to radiation GO:0009314 151 0.014
regulation of protein polymerization GO:0032271 63 0.014
Yeast Mouse Fly
replicative cell aging GO:0001302 3 0.013
endomembrane system organization GO:0010256 196 0.013
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.013
ion transmembrane transport GO:0034220 338 0.013
regulation of stress activated mapk cascade GO:0032872 84 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
negative regulation of rho gtpase activity GO:0034259 4 0.013
cilium organization GO:0044782 68 0.013
behavior GO:0007610 112 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
peptide transport GO:0015833 74 0.013
embryonic placenta development GO:0001892 1 0.013
single organism cell adhesion GO:0098602 179 0.013
divalent inorganic cation homeostasis GO:0072507 136 0.013
regulation of protein processing GO:0070613 150 0.013
regulation of leukocyte proliferation GO:0070663 67 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
lipid localization GO:0010876 106 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.012
regulation of protein catabolic process GO:0042176 155 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
positive regulation of cell migration GO:0030335 172 0.012
organelle fission GO:0048285 149 0.012
epithelial cell migration GO:0010631 119 0.012
Fly
carbohydrate metabolic process GO:0005975 207 0.012
positive regulation of secretion GO:0051047 116 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
positive regulation of endocytosis GO:0045807 42 0.012
wnt signaling pathway GO:0016055 156 0.012
oxidation reduction process GO:0055114 396 0.012
lymphocyte activation GO:0046649 133 0.012
chromatin organization GO:0006325 351 0.012
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.012
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.012
regulation of receptor mediated endocytosis GO:0048259 32 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
single organism reproductive process GO:0044702 98 0.012
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
generation of neurons GO:0048699 152 0.012
response to axon injury GO:0048678 1 0.012
actin filament organization GO:0007015 128 0.012
Yeast Mouse Fly
negative regulation of proteolysis GO:0045861 132 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.012
organelle assembly GO:0070925 176 0.012
positive regulation of cell size GO:0045793 3 0.012
cytosolic calcium ion homeostasis GO:0051480 89 0.012
cytokinesis GO:0000910 96 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
epithelial cell differentiation GO:0030855 141 0.012
Fly
establishment of protein localization to organelle GO:0072594 172 0.012
golgi organization GO:0007030 38 0.011
response to lipid GO:0033993 206 0.011
positive regulation of dendrite morphogenesis GO:0050775 3 0.011
cellular lipid metabolic process GO:0044255 303 0.011
calcium ion homeostasis GO:0055074 122 0.011
anterograde axon cargo transport GO:0008089 1 0.011
regulation of neuron differentiation GO:0045664 70 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of cell activation GO:0050865 125 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
negative regulation of transferase activity GO:0051348 124 0.011
regulation of nervous system development GO:0051960 88 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
response to other organism GO:0051707 261 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
mitochondrion transport along microtubule GO:0047497 3 0.011
positive regulation of potassium ion transport GO:0043268 15 0.011
positive regulation of catabolic process GO:0009896 310 0.011
regulation of oocyte development GO:0060281 1 0.011
regulation of camp metabolic process GO:0030814 52 0.011
tissue morphogenesis GO:0048729 96 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
regulation of cell growth GO:0001558 135 0.011
cyclic nucleotide metabolic process GO:0009187 82 0.011
meiotic chromosome segregation GO:0045132 4 0.011
negative regulation of axonogenesis GO:0050771 4 0.011
protein polymerization GO:0051258 71 0.011
Yeast Mouse Fly
neuron differentiation GO:0030182 138 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
response to virus GO:0009615 126 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
leukocyte proliferation GO:0070661 74 0.011
intracellular mrna localization GO:0008298 1 0.011
positive regulation of response to wounding GO:1903036 28 0.011
neuron projection development GO:0031175 106 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
maintenance of cell polarity GO:0030011 2 0.011
response to oxygen containing compound GO:1901700 369 0.011
protein autophosphorylation GO:0046777 123 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
pattern specification process GO:0007389 43 0.011
response to growth factor GO:0070848 205 0.011
muscle cell differentiation GO:0042692 63 0.011
leukocyte activation GO:0045321 164 0.011
negative regulation of protein processing GO:0010955 142 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
regulation of peptidase activity GO:0052547 180 0.010
regulation of protein transport GO:0051223 213 0.010
negative regulation of developmental process GO:0051093 247 0.010
embryo development GO:0009790 123 0.010
positive regulation of cytoskeleton organization GO:0051495 83 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
response to wounding GO:0009611 168 0.010
negative regulation of cell growth GO:0030308 83 0.010
regulation of response to wounding GO:1903034 101 0.010
establishment of nucleus localization GO:0040023 1 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
negative regulation of nucleotide metabolic process GO:0045980 29 0.010
positive regulation of ion transport GO:0043270 87 0.010
blood vessel morphogenesis GO:0048514 162 0.010

TWF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.059
nervous system disease DOID:863 431 0.059
cancer DOID:162 167 0.038
disease of cellular proliferation DOID:14566 174 0.038
organ system cancer DOID:0050686 164 0.034
gastrointestinal system cancer DOID:3119 52 0.025
eye and adnexa disease DOID:1492 150 0.024
eye disease DOID:5614 149 0.020
retinal disease DOID:5679 118 0.016
retinal degeneration DOID:8466 89 0.016
immune system disease DOID:2914 155 0.016
hematopoietic system disease DOID:74 100 0.016