|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
1.000
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
1.000
|
Yeast Mouse Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
1.000
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
1.000
|
Yeast Mouse |
|
|
actin filament organization
|
GO:0007015 |
128 |
1.000
|
Yeast Mouse Fly |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
1.000
|
Mouse |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
1.000
|
Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
1.000
|
Yeast Mouse Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
1.000
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
1.000
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
1.000
|
Yeast Mouse |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
1.000
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
1.000
|
Fly |
|
|
associative learning
|
GO:0008306 |
1 |
1.000
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
Fly |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
1.000
|
Mouse |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
1.000
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
1.000
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
1.000
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
1.000
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
1.000
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
1.000
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
1.000
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
1.000
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
1.000
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
1.000
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
1.000
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
1.000
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
1.000
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
1.000
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
1.000
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
1.000
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
1.000
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
1.000
|
Worm |
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
1.000
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
1.000
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
1.000
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
1.000
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
1.000
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
1.000
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
1.000
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
1.000
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
1.000
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
1.000
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
1.000
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
1.000
|
Yeast Mouse |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
1.000
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
1.000
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
1.000
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
1.000
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.999
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.999
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.999
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.999
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.999
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.999
|
Yeast Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.999
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.999
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.999
|
Yeast Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.999
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.999
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.999
|
Fly |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.999
|
Mouse |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.999
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.999
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.999
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.999
|
Fly |
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.999
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.999
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.999
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.999
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.998
|
Fly |
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.998
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.998
|
Worm |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.998
|
|
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.998
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.998
|
Mouse |
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.998
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.998
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.998
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.998
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.997
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.997
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.997
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.997
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.997
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.997
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.996
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.996
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.996
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.996
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.996
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.996
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.996
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.996
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.996
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.996
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.996
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.995
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.995
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.995
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.995
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.994
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.994
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.993
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.993
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.993
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.993
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.993
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.992
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.992
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.992
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.992
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.992
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.991
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.990
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.990
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.989
|
Fly |
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.989
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.989
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.988
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.988
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.988
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.988
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.988
|
Fly |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.988
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.988
|
Mouse Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.988
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
4 |
0.988
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.987
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.987
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.986
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.986
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.986
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.986
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.986
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.986
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.985
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.985
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.984
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.984
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.984
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.983
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.983
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.983
|
Mouse |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.982
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.981
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.981
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.980
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.979
|
Fly |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.978
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.978
|
Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.975
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.973
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.972
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.972
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.971
|
Fly |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.967
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.966
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.966
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.965
|
|
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.964
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.963
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.961
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.961
|
Fly |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.961
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.960
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.960
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.959
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.959
|
Fly |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.959
|
|
|
|
memory
|
GO:0007613 |
3 |
0.959
|
Fly |
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.959
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.958
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.957
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.957
|
Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.957
|
Fly |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.954
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
14 |
0.954
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.952
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.951
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.951
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.950
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.950
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.949
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.945
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.945
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.944
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.941
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.940
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.940
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.940
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.939
|
Worm |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.939
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.935
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.935
|
Fly |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.934
|
Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.934
|
Worm Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.932
|
Mouse |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.928
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.928
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.926
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.926
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.925
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.925
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.925
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.922
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.922
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.921
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.917
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.915
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.913
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.912
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.911
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.911
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.909
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.903
|
Fly |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.902
|
|
|
|
learning
|
GO:0007612 |
11 |
0.901
|
Fly |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.900
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.899
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.897
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.896
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.895
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.895
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.895
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.894
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.893
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.893
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.892
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.892
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.889
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.884
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.883
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.882
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.881
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.880
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.876
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.875
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.869
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.868
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.867
|
|
|
|
syncytium formation
|
GO:0006949 |
4 |
0.866
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.866
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.865
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.860
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.860
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.856
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.855
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.854
|
Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.854
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.849
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.846
|
Fly |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.844
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.841
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.832
|
Mouse |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.828
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.827
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.825
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.825
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.822
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.821
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.821
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.821
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.817
|
Fly |
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.816
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.816
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.812
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.811
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.811
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.811
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.809
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.806
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.800
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.796
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.779
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.778
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.777
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.777
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.776
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.776
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.774
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.769
|
Fly |
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.762
|
|
|
|
vesicle coating
|
GO:0006901 |
9 |
0.759
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.756
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.755
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.754
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.753
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.752
|
Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.746
|
Fly |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.745
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.744
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.738
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.732
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.726
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.725
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.713
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.711
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.709
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.705
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.699
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.698
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.697
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.696
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.695
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.689
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.688
|
|
|
|
interleukin 15 mediated signaling pathway
|
GO:0035723 |
1 |
0.685
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.684
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.682
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.681
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.679
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.675
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.674
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.674
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.669
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.668
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.666
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.659
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.657
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.656
|
Fly |
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.656
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.656
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.654
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.650
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.649
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.644
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.644
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
40 |
0.642
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.637
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.634
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.632
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.632
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.628
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.625
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.619
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.607
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.604
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.604
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.602
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
21 |
0.597
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.595
|
Fly |
|
|
regulation of lamellipodium morphogenesis
|
GO:2000392 |
4 |
0.593
|
|
|
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.592
|
|
|
|
negative regulation of transforming growth factor beta1 production
|
GO:0032911 |
2 |
0.584
|
|
|
|
phosphatidylinositol 3 phosphate biosynthetic process
|
GO:0036092 |
3 |
0.580
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.575
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.575
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.575
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.574
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.564
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.564
|
|
|
|
positive regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010641 |
2 |
0.563
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.554
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
10 |
0.551
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.550
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.547
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.545
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.545
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.544
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.544
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.534
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.532
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.532
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.528
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.528
|
|
|
|
system process
|
GO:0003008 |
349 |
0.527
|
Fly |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.522
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.520
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.518
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.510
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.505
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.495
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.488
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.483
|
Worm |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.483
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.483
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.482
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.481
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.479
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.479
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.478
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.467
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.463
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.460
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.458
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.457
|
Human |
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.455
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.454
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.453
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.446
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.443
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.441
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.440
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.438
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.438
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.433
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.432
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.427
|
|
|
|
regulation of store operated calcium channel activity
|
GO:1901339 |
4 |
0.427
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.425
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
13 |
0.423
|
|
|
|
positive regulation of glucose import in response to insulin stimulus
|
GO:2001275 |
3 |
0.420
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
15 |
0.417
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.416
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.412
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.408
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.407
|
|
|
|
protein lipid complex assembly
|
GO:0065005 |
12 |
0.402
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.400
|
Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.399
|
Fly |
|
|
gastrulation
|
GO:0007369 |
51 |
0.397
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.395
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.391
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.388
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.388
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.385
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.379
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.378
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.373
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.367
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.363
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.363
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.362
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.360
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.357
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.351
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.349
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.347
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.344
|
Worm |
|
|
negative regulation of blood circulation
|
GO:1903523 |
4 |
0.341
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.340
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.339
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.339
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.333
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.333
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.331
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.328
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.324
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.323
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.322
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.318
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.315
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.315
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.314
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.314
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
7 |
0.312
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.309
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
3 |
0.308
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.304
|
|
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.303
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.301
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.297
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.294
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.292
|
Fly |
|
|
heart process
|
GO:0003015 |
62 |
0.289
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.288
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
7 |
0.287
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.287
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.283
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.283
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.281
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.281
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
13 |
0.280
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.280
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.279
|
Fly |
|
|
response to ketone
|
GO:1901654 |
19 |
0.277
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.276
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.274
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.274
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.272
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.270
|
|
|
|
mitochondrial depolarization
|
GO:0051882 |
6 |
0.266
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.265
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.263
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.260
|
|
|
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.258
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.257
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.255
|
Mouse Fly |
|
|
lipid phosphorylation
|
GO:0046834 |
31 |
0.252
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.249
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.249
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.248
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.245
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.243
|
|
