Homo sapiens

31 known processes

POLR2E

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa

(Aliases: XAP4,RPABC1,hsRPB5,hRPB25,RPB5)

POLR2E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.615
vesicle mediated transport GO:0016192 371 0.549
receptor mediated endocytosis GO:0006898 84 0.275
transcription from rna polymerase iii promoter GO:0006383 19 0.238
Yeast
endocytosis GO:0006897 159 0.223
negative regulation of apoptotic signaling pathway GO:2001234 97 0.211
single organism membrane organization GO:0044802 268 0.193
covalent chromatin modification GO:0016569 254 0.179
membrane organization GO:0061024 292 0.178
multicellular organismal aging GO:0010259 3 0.146
embryo development GO:0009790 123 0.145
Worm
protein localization to organelle GO:0033365 280 0.144
cellular macromolecule catabolic process GO:0044265 380 0.136
cellular macromolecular complex assembly GO:0034622 324 0.133
reproductive system development GO:0061458 56 0.129
Worm
cell development GO:0048468 328 0.125
determination of adult lifespan GO:0008340 2 0.113
female gamete generation GO:0007292 2 0.096
oogenesis GO:0048477 2 0.095
cell cell signaling GO:0007267 155 0.093
growth GO:0040007 202 0.093
cellular response to dna damage stimulus GO:0006974 379 0.092
Fly
regulation of growth GO:0040008 165 0.075
regulation of apoptotic signaling pathway GO:2001233 175 0.075
embryo development ending in birth or egg hatching GO:0009792 34 0.072
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.071
positive regulation of cellular amine metabolic process GO:0033240 7 0.064
chromatin organization GO:0006325 351 0.062
protein catabolic process GO:0030163 325 0.061
transmembrane transport GO:0055085 399 0.059
cellular lipid metabolic process GO:0044255 303 0.059
posttranscriptional regulation of gene expression GO:0010608 213 0.058
neurogenesis GO:0022008 169 0.058
reproductive structure development GO:0048608 55 0.058
Worm
reproduction GO:0000003 63 0.054
Worm
lipid metabolic process GO:0006629 381 0.049
positive regulation of catabolic process GO:0009896 310 0.049
cellular component morphogenesis GO:0032989 314 0.048
dephosphorylation GO:0016311 209 0.048
regulation of ion transport GO:0043269 189 0.047
establishment of protein localization to membrane GO:0090150 121 0.046
response to organic cyclic compound GO:0014070 204 0.045
regulation of cell growth GO:0001558 135 0.044
secretion by cell GO:0032940 226 0.042
negative regulation of cell death GO:0060548 345 0.042
maintenance of location GO:0051235 112 0.040
regulation of cell cycle process GO:0010564 266 0.040
Fly
response to abiotic stimulus GO:0009628 336 0.040
regulation of cell cycle GO:0051726 393 0.040
Fly
nervous system development GO:0007399 293 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
regulation of gene expression epigenetic GO:0040029 73 0.038
apoptotic signaling pathway GO:0097190 268 0.036
positive regulation of hydrolase activity GO:0051345 331 0.036
chromatin modification GO:0016568 298 0.035
regulation of dna metabolic process GO:0051052 153 0.035
dna replication GO:0006260 116 0.034
negative regulation of apoptotic process GO:0043066 316 0.034
ion transmembrane transport GO:0034220 338 0.032
dna dependent dna replication GO:0006261 44 0.032
single organism cellular localization GO:1902580 332 0.032
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.032
reproductive process GO:0022414 106 0.032
Worm
immune response GO:0006955 307 0.032
response to metal ion GO:0010038 84 0.031
positive regulation of cellular component organization GO:0051130 376 0.031
neuron differentiation GO:0030182 138 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
amine metabolic process GO:0009308 44 0.030
protein localization to membrane GO:0072657 160 0.029
single organism reproductive process GO:0044702 98 0.029
Worm
cytoplasmic transport GO:0016482 379 0.029
cellular amine metabolic process GO:0044106 41 0.029
positive regulation of developmental process GO:0051094 314 0.028
divalent inorganic cation transport GO:0072511 158 0.028
ribonucleoside catabolic process GO:0042454 406 0.027
protein targeting GO:0006605 187 0.027
sex differentiation GO:0007548 45 0.027
Worm
mrna metabolic process GO:0016071 175 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
cellular ketone metabolic process GO:0042180 80 0.025
gonad development GO:0008406 34 0.025
Worm
translation GO:0006412 132 0.025
negative regulation of cell cycle phase transition GO:1901988 89 0.025
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
proteasomal protein catabolic process GO:0010498 176 0.024
ion homeostasis GO:0050801 230 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
nuclear transport GO:0051169 179 0.023
cellular response to organic cyclic compound GO:0071407 127 0.023
modification dependent protein catabolic process GO:0019941 209 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
secretion GO:0046903 254 0.023
cell projection organization GO:0030030 252 0.023
response to biotic stimulus GO:0009607 276 0.023
regulation of mapk cascade GO:0043408 262 0.023
microtubule cytoskeleton organization GO:0000226 176 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
regulation of transporter activity GO:0032409 82 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
response to radiation GO:0009314 151 0.022
actin filament based process GO:0030029 224 0.021
developmental process involved in reproduction GO:0003006 66 0.021
Worm
regulation of secretion by cell GO:1903530 177 0.021
cell morphogenesis GO:0000902 296 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.021
positive regulation of transport GO:0051050 336 0.021
regulation of cellular response to stress GO:0080135 244 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
cellular chemical homeostasis GO:0055082 180 0.020
histone acetylation GO:0016573 93 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
peptidyl lysine acetylation GO:0018394 101 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
internal protein amino acid acetylation GO:0006475 101 0.019
protein acylation GO:0043543 138 0.019
nucleotide catabolic process GO:0009166 408 0.019
mitotic cell cycle GO:0000278 326 0.019
Fly
positive regulation of growth GO:0045927 58 0.019
cell division GO:0051301 168 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
ras protein signal transduction GO:0007265 73 0.018
generation of neurons GO:0048699 152 0.018
peptidyl serine modification GO:0018209 106 0.018
cellular protein catabolic process GO:0044257 261 0.018
response to oxygen containing compound GO:1901700 369 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
tissue morphogenesis GO:0048729 96 0.017
g2 dna damage checkpoint GO:0031572 26 0.017
Fly
establishment of protein localization to organelle GO:0072594 172 0.017
endomembrane system organization GO:0010256 196 0.017
multi organism reproductive process GO:0044703 54 0.017
metal ion transport GO:0030001 272 0.017
small nucleolar ribonucleoprotein complex assembly GO:0000491 3 0.017
response to inorganic substance GO:0010035 127 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of transferase activity GO:0051338 355 0.016
organ morphogenesis GO:0009887 147 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
response to organonitrogen compound GO:0010243 156 0.016
ribonucleoprotein complex subunit organization GO:0071826 81 0.016
neuron development GO:0048666 113 0.016
phospholipid metabolic process GO:0006644 99 0.015
cellular protein complex assembly GO:0043623 188 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
response to hormone GO:0009725 175 0.015
mrna processing GO:0006397 133 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of locomotion GO:0040012 329 0.015
calcium ion transport GO:0006816 147 0.015
termination of rna polymerase ii transcription GO:0006369 1 0.015
positive regulation of cell death GO:0010942 263 0.015
system process GO:0003008 349 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
histone modification GO:0016570 251 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
cellular ion homeostasis GO:0006873 168 0.014
response to virus GO:0009615 126 0.014
biological adhesion GO:0022610 331 0.014
development of primary sexual characteristics GO:0045137 35 0.014
Worm
innate immune response GO:0045087 178 0.014
multicellular organism reproduction GO:0032504 42 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
aging GO:0007568 66 0.014
erk1 and erk2 cascade GO:0070371 104 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
regulation of dna dependent dna replication GO:0090329 19 0.013
chemical homeostasis GO:0048878 306 0.013
response to purine containing compound GO:0014074 40 0.013
protein targeting to nucleus GO:0044744 104 0.013
internal peptidyl lysine acetylation GO:0018393 97 0.013
lipid localization GO:0010876 106 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
regulation of binding GO:0051098 111 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
purine nucleoside catabolic process GO:0006152 398 0.013
fatty acid metabolic process GO:0006631 115 0.013
defense response GO:0006952 315 0.013
negative regulation of cellular component organization GO:0051129 235 0.012
rna interference GO:0016246 4 0.012
regulation of transmembrane transport GO:0034762 139 0.012
response to external biotic stimulus GO:0043207 261 0.012
single organism nuclear import GO:1902593 104 0.012
cellular response to steroid hormone stimulus GO:0071383 37 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
response to lipid GO:0033993 206 0.012
cardiovascular system development GO:0072358 262 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
dna damage checkpoint GO:0000077 68 0.012
Fly
regulation of mitotic cell cycle GO:0007346 189 0.012
Fly
small gtpase mediated signal transduction GO:0007264 78 0.012
dna integrity checkpoint GO:0031570 71 0.012
Fly
establishment of organelle localization GO:0051656 59 0.011
response to temperature stimulus GO:0009266 22 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
response to growth factor GO:0070848 205 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
regulation of cell projection organization GO:0031344 107 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
sexual reproduction GO:0019953 37 0.010
regulation of intracellular transport GO:0032386 195 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
coenzyme metabolic process GO:0006732 65 0.010
response to other organism GO:0051707 261 0.010
locomotory behavior GO:0007626 1 0.010
circulatory system development GO:0072359 262 0.010

POLR2E disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010