Homo sapiens

31 known processes

POLR2K

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

(Aliases: RPABC4,RPB7.0,hsRPB10a,RPB12,ABC10-alpha,hRPB7.0,RPB10alpha)

POLR2K biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female gamete generation GO:0007292 2 0.569
post embryonic development GO:0009791 2 0.283
Worm
protein deubiquitination GO:0016579 79 0.275
cellular macromolecular complex assembly GO:0034622 324 0.253
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.210
alcohol metabolic process GO:0006066 114 0.201
positive regulation of catabolic process GO:0009896 310 0.151
oogenesis GO:0048477 2 0.151
regulation of proteasomal protein catabolic process GO:0061136 87 0.120
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.087
organic hydroxy compound metabolic process GO:1901615 147 0.081
glycerophospholipid metabolic process GO:0006650 84 0.075
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.073
positive regulation of cellular catabolic process GO:0031331 284 0.065
chromatin organization GO:0006325 351 0.061
regulation of transferase activity GO:0051338 355 0.057
regulation of cellular protein catabolic process GO:1903362 96 0.055
lipid biosynthetic process GO:0008610 177 0.052
receptor mediated endocytosis GO:0006898 84 0.050
cardiovascular system development GO:0072358 262 0.049
protein import into mitochondrial matrix GO:0030150 1 0.048
cellular protein complex assembly GO:0043623 188 0.047
determination of adult lifespan GO:0008340 2 0.047
nervous system development GO:0007399 293 0.046
regulation of ligase activity GO:0051340 29 0.046
phosphatidylinositol biosynthetic process GO:0006661 25 0.044
cyclin catabolic process GO:0008054 6 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.042
nucleus localization GO:0051647 1 0.041
establishment of nucleus localization GO:0040023 1 0.041
peptidyl lysine modification GO:0018205 144 0.040
multicellular organismal aging GO:0010259 3 0.040
cell development GO:0048468 328 0.040
single organism reproductive process GO:0044702 98 0.039
Worm
negative regulation of cell proliferation GO:0008285 228 0.037
protein localization to organelle GO:0033365 280 0.037
metaphase anaphase transition of cell cycle GO:0044784 21 0.036
autophagy GO:0006914 88 0.036
regulation of chromosome organization GO:0033044 103 0.036
positive regulation of protein catabolic process GO:0045732 75 0.036
mitotic sister chromatid separation GO:0051306 18 0.034
glycerolipid metabolic process GO:0046486 107 0.034
meiotic chromosome segregation GO:0045132 4 0.033
protein modification by small protein removal GO:0070646 92 0.032
phospholipid metabolic process GO:0006644 99 0.031
phosphatidylinositol metabolic process GO:0046488 53 0.031
regulation of meiotic cell cycle GO:0051445 4 0.031
protein catabolic process GO:0030163 325 0.031
embryo development GO:0009790 123 0.030
Worm
cellular macromolecule catabolic process GO:0044265 380 0.030
neurogenesis GO:0022008 169 0.029
segmentation GO:0035282 4 0.029
nuclear migration GO:0007097 1 0.028
cell projection morphogenesis GO:0048858 129 0.028
covalent chromatin modification GO:0016569 254 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.026
chromatin modification GO:0016568 298 0.026
glycerophospholipid biosynthetic process GO:0046474 40 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
positive regulation of cell cycle process GO:0090068 106 0.026
regulation of protein catabolic process GO:0042176 155 0.025
glycerolipid biosynthetic process GO:0045017 51 0.024
positive regulation of developmental process GO:0051094 314 0.024
cell division GO:0051301 168 0.024
positive regulation of cellular protein catabolic process GO:1903364 37 0.024
protein targeting GO:0006605 187 0.023
growth GO:0040007 202 0.023
vesicle mediated transport GO:0016192 371 0.023
rna interference GO:0016246 4 0.022
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.022
single organism cellular localization GO:1902580 332 0.022
regulation of cellular response to stress GO:0080135 244 0.022
positive regulation of cell cycle GO:0045787 140 0.022
endocytosis GO:0006897 159 0.021
regulation of growth GO:0040008 165 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
regulation of mitotic sister chromatid segregation GO:0033047 27 0.020
regulation of sister chromatid segregation GO:0033045 27 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
phospholipid biosynthetic process GO:0008654 44 0.020
protein acetylation GO:0006473 116 0.019
regulation of cell division GO:0051302 116 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
blastoderm segmentation GO:0007350 2 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
circulatory system development GO:0072359 262 0.019
liposaccharide metabolic process GO:1903509 27 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
regulation of proteolysis GO:0030162 293 0.019
lipoprotein metabolic process GO:0042157 42 0.018
cellular ketone metabolic process GO:0042180 80 0.018
cellular lipid metabolic process GO:0044255 303 0.018
epithelial cell proliferation GO:0050673 128 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
glycolipid biosynthetic process GO:0009247 12 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
transmembrane transport GO:0055085 399 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
positive regulation of kinase activity GO:0033674 204 0.017
guanosine containing compound metabolic process GO:1901068 244 0.016
nuclear division GO:0000280 128 0.016
tripartite regional subdivision GO:0007351 2 0.016
cellular amine metabolic process GO:0044106 41 0.016
anterior posterior axis specification GO:0009948 2 0.016
oocyte differentiation GO:0009994 2 0.016
cell projection organization GO:0030030 252 0.016
negative regulation of catabolic process GO:0009895 104 0.016
positive regulation of mitotic cell cycle GO:0045931 60 0.016
dephosphorylation GO:0016311 209 0.016
protein lipidation GO:0006497 33 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
cytoplasmic transport GO:0016482 379 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
positive regulation of chromosome organization GO:2001252 41 0.015
isoprenoid metabolic process GO:0006720 39 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
gpi anchor metabolic process GO:0006505 11 0.014
adult locomotory behavior GO:0008344 1 0.014
locomotory behavior GO:0007626 1 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
negative regulation of hydrolase activity GO:0051346 182 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
gtp metabolic process GO:0046039 239 0.013
multicellular organism reproduction GO:0032504 42 0.013
positive regulation of organelle organization GO:0010638 195 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
mitotic sister chromatid segregation GO:0000070 53 0.012
glycolipid metabolic process GO:0006664 27 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
chromosome segregation GO:0007059 114 0.012
neuron development GO:0048666 113 0.012
system process GO:0003008 349 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
positive regulation of proteolysis GO:0045862 142 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
generation of neurons GO:0048699 152 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
regulation of cell differentiation GO:0045595 393 0.012
protein ubiquitination GO:0016567 314 0.012
cell morphogenesis GO:0000902 296 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of mitotic sister chromatid separation GO:0010965 27 0.011
carbohydrate metabolic process GO:0005975 207 0.011
organophosphate catabolic process GO:0046434 430 0.011
regulation of autophagy GO:0010506 52 0.011
regulation of chromosome segregation GO:0051983 44 0.011
positive regulation of mitosis GO:0045840 25 0.011
protein acylation GO:0043543 138 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
cellular homeostasis GO:0019725 196 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
regulation of kinase activity GO:0043549 314 0.011
establishment of organelle localization GO:0051656 59 0.011
reproductive process GO:0022414 106 0.011
Worm
protein o linked glycosylation GO:0006493 21 0.011
mapk cascade GO:0000165 288 0.011
negative regulation of protein catabolic process GO:0042177 59 0.010
double strand break repair GO:0006302 101 0.010
nucleotide catabolic process GO:0009166 408 0.010
peripheral nervous system development GO:0007422 2 0.010
mitotic nuclear division GO:0007067 119 0.010
organic hydroxy compound catabolic process GO:1901616 22 0.010

POLR2K disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.023
inherited metabolic disorder DOID:655 242 0.023