Homo sapiens

31 known processes

POLR2J

polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa

(Aliases: hRPB14,RPB11m,RPB11A,MGC71910,RPB11,POLR2J1)

POLR2J biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of glycoprotein metabolic process GO:1903019 8 0.241
regulation of mitotic cell cycle GO:0007346 189 0.149
amyloid precursor protein biosynthetic process GO:0042983 4 0.113
regulation of reactive oxygen species metabolic process GO:2000377 41 0.113
regulation of amyloid precursor protein biosynthetic process GO:0042984 4 0.099
cellular response to dna damage stimulus GO:0006974 379 0.089
membrane organization GO:0061024 292 0.088
post embryonic development GO:0009791 2 0.087
Worm
reactive oxygen species metabolic process GO:0072593 75 0.086
negative regulation of cell cycle GO:0045786 193 0.073
carbohydrate derivative biosynthetic process GO:1901137 207 0.072
mitotic cell cycle GO:0000278 326 0.072
cell adhesion GO:0007155 325 0.071
negative regulation of apoptotic process GO:0043066 316 0.071
cellular lipid metabolic process GO:0044255 303 0.070
cell division GO:0051301 168 0.064
negative regulation of amyloid precursor protein biosynthetic process GO:0042985 2 0.060
regulation of glycoprotein metabolic process GO:1903018 19 0.060
biological adhesion GO:0022610 331 0.058
negative regulation of cell death GO:0060548 345 0.051
single organism membrane organization GO:0044802 268 0.049
positive regulation of mitochondrial calcium ion concentration GO:0051561 8 0.047
negative regulation of protein metabolic process GO:0051248 391 0.047
regulation of cell cycle GO:0051726 393 0.046
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.045
rna 3 end processing GO:0031123 35 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.043
positive regulation of catabolic process GO:0009896 310 0.041
positive regulation of cellular amine metabolic process GO:0033240 7 0.040
adult locomotory behavior GO:0008344 1 0.037
determination of adult lifespan GO:0008340 2 0.036
locomotory behavior GO:0007626 1 0.035
negative regulation of glycoprotein biosynthetic process GO:0010561 5 0.034
apoptotic mitochondrial changes GO:0008637 57 0.034
negative regulation of programmed cell death GO:0043069 321 0.033
superoxide anion generation GO:0042554 11 0.033
positive regulation of cellular component organization GO:0051130 376 0.032
positive regulation of cell death GO:0010942 263 0.032
mrna 3 end processing GO:0031124 24 0.031
intrinsic apoptotic signaling pathway GO:0097193 127 0.031
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.030
dna repair GO:0006281 198 0.030
positive regulation of hydrolase activity GO:0051345 331 0.028
cell cycle phase transition GO:0044770 173 0.027
protein oligomerization GO:0051259 173 0.027
negative regulation of cell cycle phase transition GO:1901988 89 0.026
membrane fusion GO:0061025 43 0.026
regulation of mitochondrion organization GO:0010821 54 0.025
cell cycle checkpoint GO:0000075 117 0.024
regulation of cell cycle process GO:0010564 266 0.023
divalent inorganic cation homeostasis GO:0072507 136 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
mitochondrion organization GO:0007005 156 0.022
positive regulation of exocytosis GO:0045921 35 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
protein localization to membrane GO:0072657 160 0.021
motor neuron axon guidance GO:0008045 2 0.021
chemical homeostasis GO:0048878 306 0.021
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
regulation of proteolysis GO:0030162 293 0.021
single organism membrane fusion GO:0044801 37 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
apoptotic signaling pathway GO:0097190 268 0.020
protein processing GO:0016485 226 0.020
protein homooligomerization GO:0051260 100 0.020
regulation of membrane potential GO:0042391 95 0.019
cellular amine metabolic process GO:0044106 41 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
cation transport GO:0006812 331 0.019
g2 dna damage checkpoint GO:0031572 26 0.019
protein maturation GO:0051604 233 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
organelle fusion GO:0048284 36 0.018
protein catabolic process GO:0030163 325 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
regulation of protein localization GO:0032880 296 0.018
engulfment of apoptotic cell GO:0043652 2 0.018
response to nitrogen compound GO:1901698 184 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
receptor mediated endocytosis GO:0006898 84 0.017
Worm
establishment of protein localization to membrane GO:0090150 121 0.017
transmembrane transport GO:0055085 399 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
dna damage checkpoint GO:0000077 68 0.016
cellular ketone metabolic process GO:0042180 80 0.016
regulation of superoxide metabolic process GO:0090322 6 0.016
multicellular organismal aging GO:0010259 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
gtp metabolic process GO:0046039 239 0.016
regulation of intracellular transport GO:0032386 195 0.016
positive regulation of mitochondrion organization GO:0010822 30 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
response to oxygen containing compound GO:1901700 369 0.015
protein ubiquitination GO:0016567 314 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
divalent inorganic cation transport GO:0072511 158 0.015
actin filament based process GO:0030029 224 0.015
amine metabolic process GO:0009308 44 0.015
glycoprotein biosynthetic process GO:0009101 91 0.015
negative regulation of axonogenesis GO:0050771 4 0.015
calcium ion homeostasis GO:0055074 122 0.015
positive regulation of transport GO:0051050 336 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
mitochondrial transport GO:0006839 60 0.015
positive regulation of protein targeting to membrane GO:0090314 8 0.015
metal ion homeostasis GO:0055065 169 0.015
protein targeting GO:0006605 187 0.014
ion homeostasis GO:0050801 230 0.014
positive regulation of peptidase activity GO:0010952 88 0.014
neurogenesis GO:0022008 169 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
glycoprotein metabolic process GO:0009100 110 0.014
immune response GO:0006955 307 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
positive regulation of intracellular transport GO:0032388 104 0.014
response to lipid GO:0033993 206 0.013
optic nerve development GO:0021554 2 0.013
negative regulation of axon extension GO:0030517 2 0.013
monovalent inorganic cation transport GO:0015672 128 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
dna templated transcription termination GO:0006353 3 0.013
Yeast
organelle fission GO:0048285 149 0.013
oogenesis GO:0048477 2 0.013
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
nucleotide catabolic process GO:0009166 408 0.013
mrna processing GO:0006397 133 0.013
negative regulation of protein maturation GO:1903318 142 0.013
phospholipid metabolic process GO:0006644 99 0.013
positive regulation of immune response GO:0050778 159 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
positive regulation of immune system process GO:0002684 283 0.013
organophosphate catabolic process GO:0046434 430 0.012
purine containing compound catabolic process GO:0072523 411 0.012
mrna metabolic process GO:0016071 175 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
regulation of protein catabolic process GO:0042176 155 0.012
amyloid precursor protein metabolic process GO:0042982 17 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
single organism cellular localization GO:1902580 332 0.012
multi organism cellular process GO:0044764 156 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
t cell activation GO:0042110 99 0.012
response to organic cyclic compound GO:0014070 204 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.012
protein targeting to membrane GO:0006612 42 0.012
segmentation GO:0035282 4 0.012
central nervous system development GO:0007417 123 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
translational initiation GO:0006413 48 0.011
transcription from rna polymerase iii promoter GO:0006383 19 0.011
secretion GO:0046903 254 0.011
regulation of cell growth GO:0001558 135 0.011
neurological system process GO:0050877 163 0.011
regulation of protein maturation GO:1903317 150 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
defense response GO:0006952 315 0.011
positive regulation of organelle organization GO:0010638 195 0.011
sex differentiation GO:0007548 45 0.011
Worm
dna templated transcription initiation GO:0006352 35 0.011
melanin metabolic process GO:0006582 1 0.011
vesicle mediated transport GO:0016192 371 0.011
Worm
regulation of leukocyte differentiation GO:1902105 61 0.011
gtp catabolic process GO:0006184 237 0.011
cranial nerve development GO:0021545 4 0.011
protein localization to organelle GO:0033365 280 0.011
regulation of peptidase activity GO:0052547 180 0.011
blastocyst development GO:0001824 3 0.011
regulation of glycoprotein biosynthetic process GO:0010559 14 0.011
regulation of cellular response to stress GO:0080135 244 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
chromosome segregation GO:0007059 114 0.011
positive regulation of mitochondrial fission GO:0090141 7 0.011
regulation of cellular component movement GO:0051270 334 0.011
response to cocaine GO:0042220 1 0.011
negative regulation of proteolysis GO:0045861 132 0.011
cell substrate adhesion GO:0031589 132 0.011
negative regulation of cell growth GO:0030308 83 0.011
mitotic cell cycle process GO:1903047 286 0.011
endomembrane system organization GO:0010256 196 0.010
endocytosis GO:0006897 159 0.010
Worm
cellular cation homeostasis GO:0030003 163 0.010
innate immune response GO:0045087 178 0.010
negative regulation of protein processing GO:0010955 142 0.010
positive regulation of phosphorylation GO:0042327 394 0.010
regulation of secretion by cell GO:1903530 177 0.010
release of cytochrome c from mitochondria GO:0001836 35 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
response to organonitrogen compound GO:0010243 156 0.010
nervous system development GO:0007399 293 0.010
peripheral nervous system development GO:0007422 2 0.010

POLR2J disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
nervous system disease DOID:863 431 0.014
eye disease DOID:5614 149 0.011