Homo sapiens

0 known processes

USP50

ubiquitin specific peptidase 50

USP50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid transmembrane transport GO:0003333 20 0.617
ion transmembrane transport GO:0034220 338 0.496
chloride transmembrane transport GO:1902476 38 0.421
organic anion transport GO:0015711 103 0.294
organonitrogen compound biosynthetic process GO:1901566 200 0.239
anion transport GO:0006820 161 0.236
anion transmembrane transport GO:0098656 76 0.211
chloride transport GO:0006821 41 0.194
carboxylic acid transport GO:0046942 63 0.163
modified amino acid transport GO:0072337 11 0.149
purine containing compound biosynthetic process GO:0072522 88 0.145
nitrogen compound transport GO:0071705 191 0.140
organic acid transport GO:0015849 65 0.127
monocarboxylic acid metabolic process GO:0032787 185 0.121
transmembrane transport GO:0055085 399 0.119
inorganic anion transmembrane transport GO:0098661 47 0.117
amino acid transport GO:0006865 28 0.111
post embryonic development GO:0009791 2 0.100
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.097
cellular amino acid metabolic process GO:0006520 116 0.096
endomembrane system organization GO:0010256 196 0.095
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.090
single organism membrane organization GO:0044802 268 0.089
Yeast
cellular ketone metabolic process GO:0042180 80 0.089
nucleoside phosphate biosynthetic process GO:1901293 109 0.087
cation transport GO:0006812 331 0.087
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.082
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.080
proline transport GO:0015824 4 0.078
regulation of cellular ketone metabolic process GO:0010565 50 0.074
carbohydrate derivative biosynthetic process GO:1901137 207 0.074
aspartate transport GO:0015810 5 0.072
cation transmembrane transport GO:0098655 238 0.071
ribonucleoside catabolic process GO:0042454 406 0.071
ribonucleoside triphosphate metabolic process GO:0009199 412 0.068
inorganic ion transmembrane transport GO:0098660 231 0.067
single organism cellular localization GO:1902580 332 0.067
Yeast
determination of adult lifespan GO:0008340 2 0.067
system process GO:0003008 349 0.066
lipid metabolic process GO:0006629 381 0.065
membrane organization GO:0061024 292 0.061
Yeast
negative regulation of cell death GO:0060548 345 0.059
purine nucleoside triphosphate metabolic process GO:0009144 412 0.058
cranial nerve development GO:0021545 4 0.057
response to oxygen containing compound GO:1901700 369 0.057
ribonucleoside monophosphate metabolic process GO:0009161 187 0.056
amino acid import GO:0043090 4 0.053
nucleoside monophosphate metabolic process GO:0009123 191 0.052
vesicle mediated transport GO:0016192 371 0.052
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.052
neurological system process GO:0050877 163 0.051
positive regulation of cellular amine metabolic process GO:0033240 7 0.051
organophosphate biosynthetic process GO:0090407 163 0.050
negative regulation of programmed cell death GO:0043069 321 0.049
positive regulation of catabolic process GO:0009896 310 0.048
nucleoside phosphate catabolic process GO:1901292 412 0.046
multicellular organismal aging GO:0010259 3 0.046
protein targeting GO:0006605 187 0.046
negative regulation of apoptotic process GO:0043066 316 0.046
protein catabolic process GO:0030163 325 0.046
Yeast
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
nucleotide biosynthetic process GO:0009165 109 0.044
l amino acid import GO:0043092 4 0.043
regulation of cellular amine metabolic process GO:0033238 11 0.043
purine nucleoside triphosphate catabolic process GO:0009146 392 0.043
oogenesis GO:0048477 2 0.042
organophosphate catabolic process GO:0046434 430 0.042
generation of precursor metabolites and energy GO:0006091 68 0.042
nuclear transport GO:0051169 179 0.041
mitotic cell cycle GO:0000278 326 0.041
Human
nerve development GO:0021675 4 0.040
glycosyl compound catabolic process GO:1901658 413 0.040
ribose phosphate biosynthetic process GO:0046390 82 0.040
alanine transport GO:0032328 3 0.039
intracellular protein transport GO:0006886 270 0.037
purine nucleoside catabolic process GO:0006152 398 0.037
oxidation reduction process GO:0055114 396 0.037
golgi organization GO:0007030 38 0.037
nucleoside catabolic process GO:0009164 408 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
purine containing compound catabolic process GO:0072523 411 0.035
amine metabolic process GO:0009308 44 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
cellular lipid metabolic process GO:0044255 303 0.034
secretion GO:0046903 254 0.033
purine nucleotide catabolic process GO:0006195 405 0.033
ribonucleotide biosynthetic process GO:0009260 81 0.032
peripheral nervous system development GO:0007422 2 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
asymmetric stem cell division GO:0098722 1 0.031
sulfur amino acid transport GO:0000101 2 0.030
protein import GO:0017038 130 0.030
neuromuscular junction development GO:0007528 3 0.030
response to metal ion GO:0010038 84 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
response to inorganic substance GO:0010035 127 0.029
nucleocytoplasmic transport GO:0006913 176 0.028
guanosine containing compound metabolic process GO:1901068 244 0.028
cofactor metabolic process GO:0051186 87 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
organic hydroxy compound metabolic process GO:1901615 147 0.028
regulation of nucleotide catabolic process GO:0030811 205 0.027
neuroblast proliferation GO:0007405 4 0.027
regulation of locomotion GO:0040012 329 0.027
inorganic anion transport GO:0015698 60 0.027
stem cell division GO:0017145 2 0.027
female gamete generation GO:0007292 2 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
response to transition metal nanoparticle GO:1990267 29 0.026
response to mercury ion GO:0046689 4 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
regulation of proteolysis GO:0030162 293 0.026
nucleobase biosynthetic process GO:0046112 4 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
dicarboxylic acid transport GO:0006835 13 0.025
regulation of protein transport GO:0051223 213 0.024
carbohydrate metabolic process GO:0005975 207 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
Yeast
cellular macromolecular complex assembly GO:0034622 324 0.023
response to organonitrogen compound GO:0010243 156 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
Human
cytoplasmic transport GO:0016482 379 0.023
gtp catabolic process GO:0006184 237 0.022
inorganic cation transmembrane transport GO:0098662 194 0.022
chemical homeostasis GO:0048878 306 0.022
nucleotide catabolic process GO:0009166 408 0.022
regulation of cellular component movement GO:0051270 334 0.022
establishment of protein localization to organelle GO:0072594 172 0.022
gtp metabolic process GO:0046039 239 0.022
response to abiotic stimulus GO:0009628 336 0.022
monocarboxylic acid transport GO:0015718 32 0.021
ribonucleoside biosynthetic process GO:0042455 25 0.021
segmentation GO:0035282 4 0.021
cell projection organization GO:0030030 252 0.021
ras protein signal transduction GO:0007265 73 0.021
fatty acid metabolic process GO:0006631 115 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
mitotic cell cycle process GO:1903047 286 0.021
Human
l amino acid transport GO:0015807 14 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
modification dependent protein catabolic process GO:0019941 209 0.020
Yeast
regulation of cellular response to stress GO:0080135 244 0.020
organelle fission GO:0048285 149 0.020
lipid modification GO:0030258 84 0.020
divalent metal ion transport GO:0070838 152 0.020
regulation of transporter activity GO:0032409 82 0.020
regulation of intracellular transport GO:0032386 195 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
regulation of transmembrane transport GO:0034762 139 0.020
l alanine transport GO:0015808 3 0.019
protein oligomerization GO:0051259 173 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
memory GO:0007613 3 0.019
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.019
regulation of cell migration GO:0030334 289 0.019
long chain fatty acid catabolic process GO:0042758 3 0.018
locomotory behavior GO:0007626 1 0.018
glycosyl compound biosynthetic process GO:1901659 27 0.018
negative regulation of transport GO:0051051 176 0.018
metal ion transport GO:0030001 272 0.018
cell division GO:0051301 168 0.018
Human
proteasomal protein catabolic process GO:0010498 176 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
protein maturation GO:0051604 233 0.018
rho protein signal transduction GO:0007266 26 0.018
isoprenoid metabolic process GO:0006720 39 0.018
regulation of transmembrane transporter activity GO:0022898 74 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
somatic stem cell division GO:0048103 1 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
cellular amine metabolic process GO:0044106 41 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
secretion by cell GO:0032940 226 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
Yeast
neurogenesis GO:0022008 169 0.017
cell cycle phase transition GO:0044770 173 0.017
d aspartate transport GO:0070777 3 0.017
nervous system development GO:0007399 293 0.017
biological adhesion GO:0022610 331 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
regeneration GO:0031099 4 0.017
cell adhesion GO:0007155 325 0.017
regulation of cell cycle process GO:0010564 266 0.016
protein localization to organelle GO:0033365 280 0.016
divalent inorganic cation transport GO:0072511 158 0.016
acidic amino acid transport GO:0015800 6 0.016
optic nerve development GO:0021554 2 0.016
somitogenesis GO:0001756 2 0.016
small molecule biosynthetic process GO:0044283 157 0.016
alcohol metabolic process GO:0006066 114 0.016
purine nucleotide biosynthetic process GO:0006164 84 0.016
protein localization to nucleus GO:0034504 136 0.016
regulation of protein localization GO:0032880 296 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
adult locomotory behavior GO:0008344 1 0.016
response to external biotic stimulus GO:0043207 261 0.016
protein localization to membrane GO:0072657 160 0.016
defense response GO:0006952 315 0.016
ion homeostasis GO:0050801 230 0.016
endocytosis GO:0006897 159 0.016
Yeast
cell morphogenesis GO:0000902 296 0.016
central nervous system development GO:0007417 123 0.016
multicellular organismal signaling GO:0035637 34 0.016
microtubule based process GO:0007017 210 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
blastoderm segmentation GO:0007350 2 0.016
cellular protein catabolic process GO:0044257 261 0.015
Yeast
mitotic nuclear division GO:0007067 119 0.015
hindbrain development GO:0030902 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
Yeast
regulation of response to external stimulus GO:0032101 222 0.015
calcium ion transport GO:0006816 147 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
innate immune response GO:0045087 178 0.015
spermatid differentiation GO:0048515 4 0.015
positive regulation of protein transport GO:0051222 135 0.015
regulation of protein complex assembly GO:0043254 147 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
single organism nuclear import GO:1902593 104 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
nucleoside monophosphate biosynthetic process GO:0009124 19 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
cell type specific apoptotic process GO:0097285 125 0.015
regulation of cytokine production GO:0001817 232 0.015
cell cell signaling GO:0007267 155 0.015
response to organic cyclic compound GO:0014070 204 0.015
regulation of kinase activity GO:0043549 314 0.014
energy derivation by oxidation of organic compounds GO:0015980 43 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
negative regulation of cell cycle GO:0045786 193 0.014
regulation of cell cycle GO:0051726 393 0.014
Human
immune response GO:0006955 307 0.014
positive regulation of cell death GO:0010942 263 0.014
response to lipid GO:0033993 206 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of protein import into nucleus GO:0042306 78 0.014
cell aging GO:0007569 52 0.014
membrane fusion GO:0061025 43 0.014
regulation of membrane potential GO:0042391 95 0.014
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
positive regulation of phosphorylation GO:0042327 394 0.013
cell growth GO:0016049 160 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
regulation of protein targeting GO:1903533 91 0.013
regulation of multi organism process GO:0043900 157 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
cation homeostasis GO:0055080 189 0.013
oocyte development GO:0048599 1 0.013
cognition GO:0050890 43 0.013
regulation of cell motility GO:2000145 299 0.013
small molecule catabolic process GO:0044282 92 0.013
organ morphogenesis GO:0009887 147 0.013
Fly
positive regulation of cell cycle GO:0045787 140 0.013
Human
compound eye development GO:0048749 1 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
response to other organism GO:0051707 261 0.013
fatty acid catabolic process GO:0009062 29 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
Yeast
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
protein polyubiquitination GO:0000209 110 0.013
positive regulation of locomotion GO:0040017 186 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
regulation of secretion by cell GO:1903530 177 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
action potential GO:0001508 34 0.013
regulation of protein catabolic process GO:0042176 155 0.013
protein ubiquitination GO:0016567 314 0.013
nuclear import GO:0051170 106 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of transferase activity GO:0051338 355 0.012
translation GO:0006412 132 0.012
regulation of mitosis GO:0007088 63 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
organic acid catabolic process GO:0016054 71 0.012
transmission of nerve impulse GO:0019226 11 0.012
positive regulation of organelle organization GO:0010638 195 0.012
purine ribonucleoside biosynthetic process GO:0046129 23 0.012
protein tetramerization GO:0051262 47 0.012
protein targeting to nucleus GO:0044744 104 0.012
oocyte differentiation GO:0009994 2 0.012
regulation of cell division GO:0051302 116 0.012
dephosphorylation GO:0016311 209 0.012
positive regulation of cell motility GO:2000147 177 0.012
cytokine production GO:0001816 247 0.012
maintenance of location GO:0051235 112 0.012
negative regulation of locomotion GO:0040013 118 0.012
terpenoid metabolic process GO:0006721 27 0.012
response to hormone GO:0009725 175 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
regulation of behavior GO:0050795 82 0.012
regulation of ion transport GO:0043269 189 0.012
replicative cell aging GO:0001302 3 0.012
monosaccharide metabolic process GO:0005996 74 0.012
anterior posterior axis specification GO:0009948 2 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
actin filament based movement GO:0030048 17 0.012
regulation of leukocyte activation GO:0002694 115 0.012
cellular carbohydrate metabolic process GO:0044262 84 0.012
protein homooligomerization GO:0051260 100 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
neuron death GO:0070997 65 0.012
cellular homeostasis GO:0019725 196 0.012
Yeast
cellular component morphogenesis GO:0032989 314 0.012
positive regulation of cell migration GO:0030335 172 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
alpha amino acid metabolic process GO:1901605 72 0.011
protein secretion GO:0009306 98 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
asymmetric neuroblast division GO:0055059 1 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.011
growth GO:0040007 202 0.011
covalent chromatin modification GO:0016569 254 0.011
pteridine containing compound metabolic process GO:0042558 7 0.011
diterpenoid metabolic process GO:0016101 20 0.011
lipid catabolic process GO:0016042 84 0.011
protein localization to plasma membrane GO:0072659 93 0.011
plasma membrane organization GO:0007009 115 0.011
chromatin modification GO:0016568 298 0.011
multi organism reproductive process GO:0044703 54 0.011
regulation of secretion GO:0051046 194 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of anatomical structure size GO:0090066 101 0.011
histone modification GO:0016570 251 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
regulation of ion transmembrane transporter activity GO:0032412 72 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
purine nucleobase biosynthetic process GO:0009113 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 98 0.011
cell substrate adhesion GO:0031589 132 0.011
nucleus localization GO:0051647 1 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
response to biotic stimulus GO:0009607 276 0.011
immune effector process GO:0002252 159 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
nucleoside biosynthetic process GO:0009163 26 0.011
response to radiation GO:0009314 151 0.011
regulation of growth GO:0040008 165 0.011
establishment of protein localization to plasma membrane GO:0090002 68 0.011
cell part morphogenesis GO:0032990 137 0.010
mitochondrial transport GO:0006839 60 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
primary alcohol metabolic process GO:0034308 17 0.010
establishment of organelle localization GO:0051656 59 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
regulation of calcium ion transport GO:0051924 79 0.010
response to unfolded protein GO:0006986 24 0.010
regulation of protein ubiquitination GO:0031396 95 0.010
regulation of protein kinase activity GO:0045859 289 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
negative regulation of transferase activity GO:0051348 124 0.010
regulation of feeding behavior GO:0060259 3 0.010
positive regulation of immune system process GO:0002684 283 0.010
response to wounding GO:0009611 168 0.010
regulation of lipid metabolic process GO:0019216 96 0.010
cellular chemical homeostasis GO:0055082 180 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
Human
regulation of ras gtpase activity GO:0032318 128 0.010
reproductive process GO:0022414 106 0.010
neurotransmitter secretion GO:0007269 4 0.010
neuronal stem cell division GO:0036445 1 0.010
positive regulation of cell differentiation GO:0045597 211 0.010

USP50 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.264
inherited metabolic disorder DOID:655 242 0.264
amino acid metabolic disorder DOID:9252 50 0.038
central nervous system disease DOID:331 186 0.027
neurodegenerative disease DOID:1289 102 0.027
nervous system disease DOID:863 431 0.027
disease of cellular proliferation DOID:14566 174 0.021
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.015
spinocerebellar degeneration DOID:2478 27 0.015
musculoskeletal system disease DOID:17 223 0.013
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011