|
|
response to salt stress
|
GO:0009651 |
3 |
0.517
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.425
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.394
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.376
|
Yeast |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.374
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.337
|
Yeast |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.326
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.324
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.308
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.271
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.270
|
Human Yeast |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.201
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.201
|
Human Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.199
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.193
|
Yeast |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.187
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.183
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.175
|
Worm Fly |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.174
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.168
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.168
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.159
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.158
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.158
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.155
|
Human Worm |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.154
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.149
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.148
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.144
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.132
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.131
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.126
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.125
|
Yeast |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.125
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.124
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.123
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.123
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.120
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.119
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.118
|
Fly |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.117
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.117
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.115
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.111
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.109
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.109
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.108
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.107
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.105
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.104
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.102
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.100
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.095
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.092
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.090
|
Worm Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.088
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.086
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.086
|
Human Yeast Worm Fly |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.086
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.082
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.082
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.081
|
Human Worm Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.080
|
Worm Fly |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.080
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.080
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.079
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.079
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.079
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.079
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.078
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.077
|
Worm |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.076
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.076
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.075
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.075
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.074
|
Yeast |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.074
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.074
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.073
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.073
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.072
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.072
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.072
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.072
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.070
|
|
|
|
memory
|
GO:0007613 |
3 |
0.068
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.068
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.066
|
Yeast Worm |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.066
|
Human Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.066
|
Fly |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.064
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.064
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.064
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.063
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.062
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.061
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.061
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.061
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.061
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.061
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.061
|
Yeast Worm |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.060
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.060
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.059
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.059
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.058
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.058
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.058
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.057
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.057
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.057
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.057
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.056
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.056
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.056
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.055
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.055
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.055
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.055
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.053
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.053
|
Human Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.053
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.053
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.053
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.053
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.053
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.053
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.052
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.052
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.052
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.052
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.052
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.052
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.052
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.052
|
Human Worm Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.051
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.051
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.051
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.050
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.050
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.050
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.050
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.049
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.049
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.049
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.049
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.049
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.048
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.048
|
Human Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.048
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.047
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.047
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.047
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.047
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.046
|
Fly |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.046
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.046
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.045
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.045
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.044
|
Human Worm Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.044
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.044
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.044
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.044
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.044
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.044
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.043
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.043
|
Human Worm |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.043
|
Human Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.042
|
|
|
|
translation
|
GO:0006412 |
132 |
0.042
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.042
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.042
|
Yeast |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.041
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.041
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.041
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.041
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.040
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.040
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.040
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.040
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.040
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.040
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.039
|
Human Worm Fly |
|
|
response to nitrosative stress
|
GO:0051409 |
4 |
0.039
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.039
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.039
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.039
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.039
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.039
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.038
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.038
|
Human Worm |
|
|
oogenesis
|
GO:0048477 |
2 |
0.038
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.038
|
Fly |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.038
|
Worm Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.038
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.038
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.037
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.037
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.037
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.037
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.036
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.036
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.036
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.036
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.036
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.036
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.036
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.036
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.035
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.035
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.035
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.035
|
Fly |
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.035
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.034
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.034
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.034
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.033
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.033
|
Human |
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.033
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.032
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.032
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.032
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.032
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
1 |
0.031
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.031
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.031
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.030
|
Fly |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.030
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.030
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.030
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.030
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.030
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.029
|
|
|
|
gabaergic neuron differentiation
|
GO:0097154 |
1 |
0.029
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.029
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.029
|
Yeast |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.029
|
|
|
|
head development
|
GO:0060322 |
108 |
0.029
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.028
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.028
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.028
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.028
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.028
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.028
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.028
|
Worm Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.028
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.028
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.028
|
Fly |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.028
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.027
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.027
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.027
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.027
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.027
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.027
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.027
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.027
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.027
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.027
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.027
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.027
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.026
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.026
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.026
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.026
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.026
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.026
|
Human |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.026
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.026
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.026
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.025
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.025
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.025
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.025
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.025
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.025
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.025
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.025
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.025
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.024
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.024
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.024
|
Human |
|
|
cell aging
|
GO:0007569 |
52 |
0.024
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.024
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.024
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.024
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.024
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.024
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.024
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.024
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.024
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.023
|
Human Worm |
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.023
|
Human Yeast Worm Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.023
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.023
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.023
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.023
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.023
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.023
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.023
|
Worm |
|
|
histone modification
|
GO:0016570 |
251 |
0.023
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.023
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.022
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.022
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.022
|
Human Worm Fly |
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.022
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.022
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.022
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.022
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.022
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.022
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.022
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.021
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.021
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.021
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.021
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.021
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.021
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.021
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.021
|
Worm |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.020
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.020
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.020
|
Human |
|
|
p38mapk cascade
|
GO:0038066 |
9 |
0.020
|
Worm |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.020
|
Fly |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.020
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.020
|
Human Worm |
|
|
reproductive process
|
GO:0022414 |
106 |
0.020
|
Yeast Worm |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.020
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.020
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.019
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.019
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.019
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.019
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.019
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.019
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.019
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.019
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.019
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.019
|
Fly |
|
|
response to virus
|
GO:0009615 |
126 |
0.019
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.019
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.019
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.019
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.019
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.019
|
Human |
|
|
sensory perception
|
GO:0007600 |
103 |
0.019
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.019
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.019
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.019
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.019
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.018
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.018
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.018
|
Worm Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.018
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.018
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.018
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.018
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.018
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.018
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.018
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.018
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.018
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.018
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.018
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.018
|
Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.018
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.018
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.018
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.017
|
Human |
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.017
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.017
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.017
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.017
|
|
|
|
system process
|
GO:0003008 |
349 |
0.017
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.017
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.017
|
|
|
|
paracrine signaling
|
GO:0038001 |
1 |
0.017
|
Fly |
|
|
cellular response to interleukin 12
|
GO:0071349 |
3 |
0.017
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.017
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.017
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.017
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.017
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.017
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.017
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.017
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.017
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.016
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.016
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.016
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.016
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.016
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.016
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.016
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.016
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
1 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
Fly |
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.016
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.016
|
|
|
|
growth
|
GO:0040007 |
202 |
0.016
|
Fly |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.016
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.016
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.016
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.016
|
Worm Fly |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.016
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.016
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.016
|
|
|
|
stress induced premature senescence
|
GO:0090400 |
5 |
0.015
|
Human |
|
|
long term memory
|
GO:0007616 |
2 |
0.015
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.015
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.015
|
|
|
|
positive regulation of dendrite development
|
GO:1900006 |
7 |
0.015
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.015
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.015
|
|
|
|
aging
|
GO:0007568 |
66 |
0.015
|
Human Fly |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.015
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.015
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.015
|
|
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.015
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.015
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.015
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.015
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.015
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.015
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.015
|
Worm Fly |
|
|
response to fungus
|
GO:0009620 |
4 |
0.015
|
Fly |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.014
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.014
|
|
|
|
cerebral cortex gabaergic interneuron differentiation
|
GO:0021892 |
1 |
0.014
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.014
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.014
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.014
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.014
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.014
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.014
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.014
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.014
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.014
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.014
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.014
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.014
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.014
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
15 |
0.014
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.014
|
Human |
|
|
cerebellum development
|
GO:0021549 |
2 |
0.014
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.014
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.014
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.014
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.014
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.014
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.014
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.014
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.013
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.013
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.013
|
Fly |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.013
|
Human |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.013
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.013
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.013
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.013
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.013
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.013
|
Fly |
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.013
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.013
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.013
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.013
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.013
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.013
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.013
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.013
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.013
|
|
