Homo sapiens

30 known processes

MAPK12

mitogen-activated protein kinase 12

(Aliases: P38GAMMA,ERK3,ERK6,SAPK-3,PRKM12,SAPK3)

MAPK12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sodium ion transmembrane transport GO:0035725 59 0.976
cardiac muscle cell contraction GO:0086003 4 0.901
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 10 0.878
neuromuscular junction development GO:0007528 3 0.794
sodium ion transport GO:0006814 61 0.778
cardiac muscle contraction GO:0060048 34 0.754
muscle contraction GO:0006936 73 0.699
cellular amine metabolic process GO:0044106 41 0.679
cardiac muscle cell action potential involved in contraction GO:0086002 21 0.649
regulation of cellular amino acid metabolic process GO:0006521 6 0.643
cardiac muscle cell action potential GO:0086001 23 0.634
actin mediated cell contraction GO:0070252 12 0.631
monovalent inorganic cation transport GO:0015672 128 0.630
actin filament based movement GO:0030048 17 0.621
regulation of cellular amine metabolic process GO:0033238 11 0.619
negative regulation of cellular amine metabolic process GO:0033239 3 0.615
regulation of muscle system process GO:0090257 53 0.602
amine metabolic process GO:0009308 44 0.601
regulation of cellular ketone metabolic process GO:0010565 50 0.598
regulation of cardiac muscle contraction GO:0055117 33 0.586
regulation of membrane repolarization GO:0060306 16 0.571
ventricular cardiac muscle cell action potential GO:0086005 15 0.565
regulation of system process GO:0044057 101 0.548
cation transmembrane transport GO:0098655 238 0.540
cellular ketone metabolic process GO:0042180 80 0.532
regulation of actin filament based movement GO:1903115 24 0.529
inorganic ion transmembrane transport GO:0098660 231 0.529
cellular amino acid metabolic process GO:0006520 116 0.523
regulation of blood vessel size GO:0050880 18 0.500
regulation of sodium ion transmembrane transport GO:1902305 23 0.491
regulation of heart contraction GO:0008016 50 0.489
action potential GO:0001508 34 0.439
striated muscle contraction GO:0006941 52 0.423
muscle system process GO:0003012 81 0.422
regulation of transmembrane transport GO:0034762 139 0.397
inorganic cation transmembrane transport GO:0098662 194 0.374
negative regulation of protein metabolic process GO:0051248 391 0.373
regulation of peptidyl cysteine s nitrosylation GO:2000169 1 0.373
actin filament based process GO:0030029 224 0.361
ion transmembrane transport GO:0034220 338 0.361
membrane repolarization GO:0086009 23 0.359
regulation of striated muscle contraction GO:0006942 37 0.351
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.350
regulation of ion transmembrane transport GO:0034765 132 0.346
system process GO:0003008 349 0.336
regulation of cardiac muscle cell contraction GO:0086004 23 0.325
protein nitrosylation GO:0017014 1 0.312
regulation of heart rate GO:0002027 38 0.308
regulation of membrane potential GO:0042391 95 0.300
negative regulation of protein modification process GO:0031400 200 0.298
regulation of tube size GO:0035150 18 0.297
regulation of blood circulation GO:1903522 59 0.274
protein homooligomerization GO:0051260 100 0.273
transmembrane transport GO:0055085 399 0.272
negative regulation of cellular protein metabolic process GO:0032269 353 0.270
regulation of muscle contraction GO:0006937 45 0.262
protein oligomerization GO:0051259 173 0.260
histone modification GO:0016570 251 0.254
Human
peptidyl threonine phosphorylation GO:0018107 41 0.248
Human
vasoconstriction GO:0042310 11 0.228
regulation of sodium ion transport GO:0002028 24 0.226
vascular process in circulatory system GO:0003018 29 0.224
regulation of ion transport GO:0043269 189 0.219
covalent chromatin modification GO:0016569 254 0.219
Human
heart contraction GO:0060047 62 0.217
regulation of metal ion transport GO:0010959 120 0.214
metal ion transport GO:0030001 272 0.209
circulatory system process GO:0003013 113 0.204
regulation of anatomical structure size GO:0090066 101 0.197
Fly
blood circulation GO:0008015 113 0.190
post embryonic development GO:0009791 2 0.179
Worm Fly
regulation of cellular component movement GO:0051270 334 0.175
peptidyl threonine modification GO:0018210 45 0.172
Human
epithelium migration GO:0090132 119 0.172
positive regulation of phosphorylation GO:0042327 394 0.147
Fly
negative regulation of peptidyl cysteine s nitrosylation GO:1902083 1 0.131
regulation of locomotion GO:0040012 329 0.130
cation transport GO:0006812 331 0.130
regulation of cell motility GO:2000145 299 0.128
peptidyl cysteine s nitrosylation GO:0018119 1 0.128
response to oxygen containing compound GO:1901700 369 0.116
Human Worm Fly
regulation of vasoconstriction GO:0019229 5 0.112
ion homeostasis GO:0050801 230 0.102
peptidyl cysteine modification GO:0018198 9 0.101
heart process GO:0003015 62 0.101
chromatin organization GO:0006325 351 0.097
Human
secretion GO:0046903 254 0.097
regulation of transferase activity GO:0051338 355 0.094
immune response GO:0006955 307 0.091
Worm Fly
protein autophosphorylation GO:0046777 123 0.090
positive regulation of cellular amine metabolic process GO:0033240 7 0.083
regulation of protein kinase activity GO:0045859 289 0.082
negative regulation of catalytic activity GO:0043086 335 0.082
negative regulation of phosphorus metabolic process GO:0010563 267 0.080
regulation of establishment of protein localization GO:0070201 242 0.072
negative regulation of phosphate metabolic process GO:0045936 267 0.072
response to organic cyclic compound GO:0014070 204 0.071
positive regulation of transport GO:0051050 336 0.069
carbohydrate metabolic process GO:0005975 207 0.067
tissue migration GO:0090130 119 0.065
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.063
regulation of secretion by cell GO:1903530 177 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.062
positive regulation of cell cycle GO:0045787 140 0.062
epithelial cell migration GO:0010631 119 0.061
regulation of anatomical structure morphogenesis GO:0022603 286 0.061
Yeast
negative regulation of protein phosphorylation GO:0001933 140 0.060
cell division GO:0051301 168 0.059
ameboidal type cell migration GO:0001667 135 0.058
protein catabolic process GO:0030163 325 0.058
cellular chemical homeostasis GO:0055082 180 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
negative regulation of multicellular organismal process GO:0051241 317 0.055
mapk cascade GO:0000165 288 0.055
Human Yeast Rat Worm Fly
chemical homeostasis GO:0048878 306 0.055
cellular ion homeostasis GO:0006873 168 0.054
lipid metabolic process GO:0006629 381 0.054
regulation of protein transport GO:0051223 213 0.053
negative regulation of phosphorylation GO:0042326 174 0.053
response to growth factor GO:0070848 205 0.052
Human Fly
ras protein signal transduction GO:0007265 73 0.052
regulation of protein localization GO:0032880 296 0.052
Human Worm
positive regulation of cell cycle process GO:0090068 106 0.051
secretion by cell GO:0032940 226 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
nucleoside catabolic process GO:0009164 408 0.050
cell activation GO:0001775 213 0.050
purine containing compound catabolic process GO:0072523 411 0.049
negative regulation of immune system process GO:0002683 136 0.049
Fly
small gtpase mediated signal transduction GO:0007264 78 0.048
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
multicellular organismal aging GO:0010259 3 0.047
Fly
determination of adult lifespan GO:0008340 2 0.047
Fly
negative regulation of secretion GO:0051048 58 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
response to lipid GO:0033993 206 0.045
Human
regulation of kinase activity GO:0043549 314 0.045
regulation of secretion GO:0051046 194 0.045
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.044
positive regulation of protein catabolic process GO:0045732 75 0.044
cell junction assembly GO:0034329 67 0.044
ribonucleoside catabolic process GO:0042454 406 0.043
positive regulation of protein phosphorylation GO:0001934 313 0.043
Fly
cell morphogenesis GO:0000902 296 0.042
regulation of purine nucleotide metabolic process GO:1900542 264 0.042
regulation of dna metabolic process GO:0051052 153 0.041
Yeast
protein localization to organelle GO:0033365 280 0.041
Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.041
purine nucleoside catabolic process GO:0006152 398 0.040
locomotory behavior GO:0007626 1 0.040
immune system development GO:0002520 195 0.039
cell junction organization GO:0034330 79 0.039
cellular cation homeostasis GO:0030003 163 0.039
nucleoside phosphate catabolic process GO:1901292 412 0.039
endomembrane system organization GO:0010256 196 0.037
regulation of protein catabolic process GO:0042176 155 0.037
response to nutrient levels GO:0031667 81 0.037
Fly
renal system process GO:0003014 25 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
b cell homeostasis GO:0001782 1 0.036
dna replication GO:0006260 116 0.036
Yeast
protein maturation GO:0051604 233 0.036
divalent metal ion transport GO:0070838 152 0.036
female gamete generation GO:0007292 2 0.036
cytoplasmic transport GO:0016482 379 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
organophosphate catabolic process GO:0046434 430 0.035
neurotransmitter secretion GO:0007269 4 0.035
lymphocyte activation GO:0046649 133 0.034
cell type specific apoptotic process GO:0097285 125 0.034
regulation of protein serine threonine kinase activity GO:0071900 179 0.033
oxidation reduction process GO:0055114 396 0.033
hematopoietic or lymphoid organ development GO:0048534 186 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.032
Human Fly
cellular response to oxygen containing compound GO:1901701 276 0.032
Human Fly
negative regulation of protein kinase activity GO:0006469 98 0.032
positive regulation of cell death GO:0010942 263 0.032
synapse organization GO:0050808 14 0.031
Fly
response to abiotic stimulus GO:0009628 336 0.031
Human Yeast Worm Fly
small molecule biosynthetic process GO:0044283 157 0.031
cellular calcium ion homeostasis GO:0006874 117 0.031
positive regulation of catabolic process GO:0009896 310 0.031
cellular component morphogenesis GO:0032989 314 0.031
Yeast
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.030
negative regulation of cell death GO:0060548 345 0.030
Human
gtp catabolic process GO:0006184 237 0.030
cell cell junction organization GO:0045216 69 0.030
peptidyl lysine modification GO:0018205 144 0.030
cytokine production GO:0001816 247 0.030
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.030
regulation of proteolysis GO:0030162 293 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.029
Human
cellular macromolecular complex assembly GO:0034622 324 0.029
regulation of intracellular transport GO:0032386 195 0.029
oogenesis GO:0048477 2 0.029
membrane organization GO:0061024 292 0.029
cytosolic calcium ion homeostasis GO:0051480 89 0.029
protein ubiquitination GO:0016567 314 0.029
regulation of protein secretion GO:0050708 86 0.029
regulation of cell cycle GO:0051726 393 0.029
Yeast Rat
negative regulation of cell proliferation GO:0008285 228 0.029
protein secretion GO:0009306 98 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
response to external biotic stimulus GO:0043207 261 0.028
Human Worm Fly
innate immune response GO:0045087 178 0.028
Worm Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
regulation of leukocyte activation GO:0002694 115 0.027
negative regulation of dna metabolic process GO:0051053 57 0.027
negative regulation of cell size GO:0045792 3 0.027
metal ion homeostasis GO:0055065 169 0.027
regulation of immunoglobulin production GO:0002637 4 0.027
leukocyte activation GO:0045321 164 0.027
response to nitrogen compound GO:1901698 184 0.027
negative regulation of programmed cell death GO:0043069 321 0.027
Human
lymphocyte homeostasis GO:0002260 4 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
positive regulation of cytokinesis GO:0032467 29 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.026
gtp metabolic process GO:0046039 239 0.025
segmentation GO:0035282 4 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.025
Yeast
regulation of cellular response to stress GO:0080135 244 0.025
Fly
cellular response to growth factor stimulus GO:0071363 197 0.025
Human Fly
positive regulation of cell proliferation GO:0008284 301 0.025
memory GO:0007613 3 0.025
circadian behavior GO:0048512 2 0.025
chromatin modification GO:0016568 298 0.025
Human
mitotic cell cycle GO:0000278 326 0.024
protein localization to nucleus GO:0034504 136 0.024
Worm
regulation of wound healing GO:0061041 56 0.024
negative regulation of kinase activity GO:0033673 106 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
regulation of cytokine production GO:0001817 232 0.024
Human
peptidyl serine phosphorylation GO:0018105 101 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
negative regulation of protein transport GO:0051224 75 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
regulation of lymphocyte activation GO:0051249 103 0.024
positive regulation of transferase activity GO:0051347 227 0.023
angiogenesis GO:0001525 147 0.023
lymphocyte proliferation GO:0046651 70 0.023
guanosine containing compound catabolic process GO:1901069 239 0.023
histone threonine phosphorylation GO:0035405 7 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
Human
reactive oxygen species metabolic process GO:0072593 75 0.023
Human Fly
regulation of cytoplasmic transport GO:1903649 149 0.023
response to other organism GO:0051707 261 0.023
Human Worm Fly
regulation of mitotic cell cycle GO:0007346 189 0.023
blood vessel development GO:0001568 172 0.022
defense response GO:0006952 315 0.022
Worm Fly
regulation of reactive oxygen species metabolic process GO:2000377 41 0.022
Human
response to wounding GO:0009611 168 0.022
response to osmotic stress GO:0006970 17 0.022
Human Yeast Worm Fly
response to oxidative stress GO:0006979 121 0.022
Worm Fly
positive regulation of apoptotic process GO:0043065 246 0.022
regulation of response to wounding GO:1903034 101 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
Human Yeast Rat Worm Fly
regulation of cytokinesis GO:0032465 45 0.022
single organism cellular localization GO:1902580 332 0.022
positive regulation of cell motility GO:2000147 177 0.022
biological adhesion GO:0022610 331 0.022
rhythmic behavior GO:0007622 2 0.022
positive regulation of immune system process GO:0002684 283 0.022
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.021
regulation of synaptic plasticity GO:0048167 3 0.021
calcium ion homeostasis GO:0055074 122 0.021
regeneration GO:0031099 4 0.021
regulation of protein processing GO:0070613 150 0.021
protein deacylation GO:0035601 39 0.021
Human
regulation of lymphocyte proliferation GO:0050670 64 0.021
regulation of cell differentiation GO:0045595 393 0.021
Human Yeast
cell projection organization GO:0030030 252 0.021
cellular response to starvation GO:0009267 58 0.021
immune effector process GO:0002252 159 0.021
leukocyte proliferation GO:0070661 74 0.021
vasculature development GO:0001944 181 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
regulation of cell adhesion GO:0030155 166 0.020
anterior posterior axis specification GO:0009948 2 0.020
regulation of mononuclear cell proliferation GO:0032944 65 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
blood vessel morphogenesis GO:0048514 162 0.020
regulation of multi organism process GO:0043900 157 0.020
Fly
cellular response to oxidative stress GO:0034599 85 0.020
Fly
negative regulation of developmental process GO:0051093 247 0.020
Yeast
regulation of immune effector process GO:0002697 91 0.020
regulation of leukocyte proliferation GO:0070663 67 0.020
sensory perception of pain GO:0019233 4 0.020
response to organonitrogen compound GO:0010243 156 0.020
maintenance of location GO:0051235 112 0.020
dephosphorylation GO:0016311 209 0.020
nuclear transport GO:0051169 179 0.020
multi organism cellular process GO:0044764 156 0.019
regulation of cell cycle process GO:0010564 266 0.019
Yeast
nitrogen compound transport GO:0071705 191 0.019
spermatid differentiation GO:0048515 4 0.019
regulation of vasculature development GO:1901342 97 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
cytokinesis GO:0000910 96 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
regulation of hormone levels GO:0010817 125 0.019
negative regulation of protein processing GO:0010955 142 0.019
interspecies interaction between organisms GO:0044419 156 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
regulation of protein complex assembly GO:0043254 147 0.019
lymphocyte apoptotic process GO:0070227 20 0.019
negative regulation of hydrolase activity GO:0051346 182 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
protein processing GO:0016485 226 0.018
forelimb morphogenesis GO:0035136 4 0.018
response to alcohol GO:0097305 64 0.018
response to biotic stimulus GO:0009607 276 0.018
Human Worm Fly
negative regulation of proteolysis GO:0045861 132 0.018
intracellular protein transport GO:0006886 270 0.018
organelle assembly GO:0070925 176 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
cellular protein catabolic process GO:0044257 261 0.018
regulation of protein maturation GO:1903317 150 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
cell adhesion GO:0007155 325 0.018
regulation of cell growth GO:0001558 135 0.018
cell cell junction assembly GO:0007043 25 0.018
receptor metabolic process GO:0043112 81 0.018
nuclear division GO:0000280 128 0.018
positive regulation of locomotion GO:0040017 186 0.018
glycoprotein metabolic process GO:0009100 110 0.018
negative regulation of protein maturation GO:1903318 142 0.018
golgi organization GO:0007030 38 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
Human
adult locomotory behavior GO:0008344 1 0.018
positive regulation of protein transport GO:0051222 135 0.017
blastoderm segmentation GO:0007350 2 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
Yeast
anion transport GO:0006820 161 0.017
positive regulation of proteolysis GO:0045862 142 0.017
rho protein signal transduction GO:0007266 26 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
positive regulation of protein ubiquitination GO:0031398 53 0.017
wound healing GO:0042060 115 0.017
central nervous system development GO:0007417 123 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
peripheral nervous system development GO:0007422 2 0.017
spermatid development GO:0007286 4 0.017
oocyte differentiation GO:0009994 2 0.017
organelle fission GO:0048285 149 0.017
regulation of growth GO:0040008 165 0.017
Fly
protein targeting GO:0006605 187 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
histone phosphorylation GO:0016572 16 0.017
growth GO:0040007 202 0.017
Fly
b cell proliferation GO:0042100 22 0.017
regulation of epithelial cell migration GO:0010632 93 0.017
microtubule based process GO:0007017 210 0.017
neurological system process GO:0050877 163 0.017
positive regulation of mapk cascade GO:0043410 190 0.017
positive regulation of intracellular transport GO:0032388 104 0.017
response to cytokine GO:0034097 232 0.016
negative regulation of b cell activation GO:0050869 6 0.016
oocyte development GO:0048599 1 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
Fly
positive regulation of kinase activity GO:0033674 204 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
vesicle mediated transport GO:0016192 371 0.016
cell cycle phase transition GO:0044770 173 0.016
negative regulation of cellular component movement GO:0051271 106 0.016
response to salt stress GO:0009651 3 0.016
Fly
cell development GO:0048468 328 0.016
Yeast
negative regulation of secretion by cell GO:1903531 52 0.016
regulation of transmembrane transporter activity GO:0022898 74 0.016
negative regulation of cell activation GO:0050866 33 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
negative regulation of organelle organization GO:0010639 126 0.016
regulation of defense response GO:0031347 154 0.016
Fly
cellular protein complex assembly GO:0043623 188 0.016
negative regulation of synaptic transmission GO:0050805 2 0.016
negative regulation of cell migration GO:0030336 102 0.016
embryo development GO:0009790 123 0.016
Worm
cellular response to nitrogen compound GO:1901699 144 0.016
single organism membrane organization GO:0044802 268 0.015
positive regulation of developmental process GO:0051094 314 0.015
Human Fly
posttranscriptional regulation of gene expression GO:0010608 213 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
regulation of vesicle mediated transport GO:0060627 130 0.015
neuroblast proliferation GO:0007405 4 0.015
regulation of ion transmembrane transporter activity GO:0032412 72 0.015
positive regulation of cell migration GO:0030335 172 0.015
apoptotic signaling pathway GO:0097190 268 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
nucleotide biosynthetic process GO:0009165 109 0.015
purine ribonucleotide biosynthetic process GO:0009152 79 0.015
cell part morphogenesis GO:0032990 137 0.015
regulation of cell migration GO:0030334 289 0.015
organic hydroxy compound biosynthetic process GO:1901617 71 0.015
negative regulation of protein secretion GO:0050709 29 0.015
regulation of homeostatic process GO:0032844 121 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of innate immune response GO:0045088 97 0.015
Fly
generation of neurons GO:0048699 152 0.015
regulation of peptidase activity GO:0052547 180 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
regulation of calcium ion transport GO:0051924 79 0.015
regulation of cell development GO:0060284 161 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
compound eye development GO:0048749 1 0.014
adaptive immune response GO:0002250 49 0.014
response to fungus GO:0009620 4 0.014
Fly
sequestering of metal ion GO:0051238 24 0.014
regulation of mapk cascade GO:0043408 262 0.014
response to estrogen GO:0043627 47 0.014
regulation of chromosome organization GO:0033044 103 0.014
Human
epithelial cell proliferation GO:0050673 128 0.014
cellular carbohydrate metabolic process GO:0044262 84 0.014
motor neuron axon guidance GO:0008045 2 0.014
viral life cycle GO:0019058 132 0.014
response to inorganic substance GO:0010035 127 0.014
Worm Fly
negative regulation of transferase activity GO:0051348 124 0.014
associative learning GO:0008306 1 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
hindbrain development GO:0030902 3 0.014
regulation of response to external stimulus GO:0032101 222 0.014
Fly
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
erk1 and erk2 cascade GO:0070371 104 0.014
protein import GO:0017038 130 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
negative regulation of cell growth GO:0030308 83 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
head development GO:0060322 108 0.014
defense response to other organism GO:0098542 129 0.014
Worm Fly
regulation of immune response GO:0050776 201 0.014
Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
sequestering of calcium ion GO:0051208 17 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
spleen development GO:0048536 1 0.014
positive regulation of cytokine production GO:0001819 167 0.013
Human
negative regulation of growth GO:0045926 97 0.013
striated muscle adaptation GO:0014888 4 0.013
nucleotide catabolic process GO:0009166 408 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
defense response to fungus GO:0050832 4 0.013
Fly
endothelial cell migration GO:0043542 86 0.013
embryonic forelimb morphogenesis GO:0035115 4 0.013
atp metabolic process GO:0046034 176 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
leukocyte apoptotic process GO:0071887 31 0.013
cellular response to lipid GO:0071396 127 0.013
Human
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of protein targeting GO:1903533 91 0.013
regulation of actin filament based process GO:0032970 141 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
production of molecular mediator of immune response GO:0002440 37 0.013
positive regulation of aldosterone metabolic process GO:0032346 2 0.013
tissue regeneration GO:0042246 3 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
neuron differentiation GO:0030182 138 0.013
negative regulation of cell cycle GO:0045786 193 0.013
Rat
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
viral process GO:0016032 146 0.013
regulation of protein binding GO:0043393 66 0.013
Human

MAPK12 disease predictions

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 13 0.733
disease of metabolism DOID:0014667 295 0.041
inherited metabolic disorder DOID:655 242 0.038
muscular disease DOID:0080000 114 0.030
musculoskeletal system disease DOID:17 223 0.030
muscle tissue disease DOID:66 113 0.025
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
myopathy DOID:423 104 0.019
central nervous system disease DOID:331 186 0.019
immune system disease DOID:2914 155 0.015
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
cardiovascular system disease DOID:1287 106 0.013
connective tissue disease DOID:65 109 0.013