|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.818
|
Human Mouse Fly |
|
|
nerve growth factor signaling pathway
|
GO:0038180 |
4 |
0.484
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.475
|
Human Mouse Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.470
|
Human Mouse Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.456
|
Human Mouse Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.442
|
Human Mouse Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.440
|
Human Mouse Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.432
|
Human Mouse Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.374
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.366
|
Human Mouse Fly |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.354
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.329
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.303
|
Human Mouse Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.297
|
Human Mouse Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.296
|
Human Mouse Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.286
|
Human Mouse Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.285
|
Human Mouse Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.280
|
Human Fly |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.280
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.263
|
Human Mouse Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.263
|
Human Mouse Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.259
|
Human Mouse Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.252
|
Human Mouse Fly |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.249
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.249
|
Human Mouse Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.242
|
Human Mouse Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.229
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.221
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.221
|
Human Mouse Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.202
|
Human Mouse Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.198
|
Human Mouse Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.193
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.192
|
Human Mouse Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.190
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.189
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.184
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.177
|
Human Mouse Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.175
|
Human Mouse Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.174
|
Human Mouse Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.174
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.174
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.172
|
Worm Fly |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.172
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.167
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.166
|
Human Mouse Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.165
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.165
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.162
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.157
|
Human Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.156
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.152
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.152
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.144
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.143
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.142
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.142
|
Human Mouse Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.139
|
Human |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.138
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.137
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.133
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.130
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.127
|
Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.125
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.124
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.124
|
Human Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.123
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.123
|
Human Mouse Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.122
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.121
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.121
|
Human Mouse Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.120
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.118
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.117
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.113
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.112
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.111
|
Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.111
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.109
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.108
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.105
|
Human Mouse Fly |
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.104
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.103
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.102
|
Human Mouse Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.101
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.101
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.099
|
Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.099
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.098
|
Human Mouse Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.097
|
Human Mouse Fly |
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.096
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.095
|
Human Worm |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.095
|
Human Mouse Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.094
|
Worm |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.092
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.092
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.092
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.092
|
Human Mouse Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.091
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.091
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.090
|
Human Mouse Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.090
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.089
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.089
|
Worm |
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.087
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.087
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.087
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.085
|
Human Mouse Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.084
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.083
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.082
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.082
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.081
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.081
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.080
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.079
|
Human Mouse Fly |
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.079
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.079
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.079
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.078
|
Fly |
|
|
inflammatory response
|
GO:0006954 |
79 |
0.076
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.075
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.075
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.075
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.075
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.075
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.074
|
Human Mouse Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.073
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.072
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.072
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.072
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.071
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.070
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.070
|
Human Mouse Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.070
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.070
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.069
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.068
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.068
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.068
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.067
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.065
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.064
|
Human Mouse Fly |
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.064
|
|
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.063
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.063
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.063
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.062
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.062
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.062
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.061
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
14 |
0.061
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.060
|
Human Mouse Fly |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.059
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.058
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.058
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.058
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.057
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.056
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.056
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.056
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.054
|
Worm |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.053
|
Human Mouse |
|
|
regeneration
|
GO:0031099 |
4 |
0.053
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.053
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.053
|
Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.052
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.052
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.052
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.052
|
Fly |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.051
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.051
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.051
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.051
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.050
|
Human Mouse Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.050
|
Fly |
|
|
cellular response to interleukin 12
|
GO:0071349 |
3 |
0.049
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.049
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.049
|
|
|
|
positive regulation of cardiac muscle adaptation
|
GO:0010615 |
1 |
0.048
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.048
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.047
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.047
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.047
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.047
|
Worm |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.046
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.046
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.045
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.045
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.045
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.045
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.044
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.044
|
Human Fly |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.044
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.044
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.044
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.043
|
Human Mouse Fly |
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.042
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.042
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.042
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.042
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.042
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.041
|
Human Fly |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.041
|
Mouse |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.041
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.040
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.040
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.040
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.040
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.039
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.039
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.039
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.038
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.038
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.038
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.038
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.037
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.037
|
Human Mouse Fly |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.037
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.036
|
Fly |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.036
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.036
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.036
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.036
|
Worm |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.036
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.035
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.035
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.035
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.035
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.035
|
Mouse |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.034
|
Fly |
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.034
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.034
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.034
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.034
|
Human Fly |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.034
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.034
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.034
|
Human Mouse Fly |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.034
|
Human |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.033
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.033
|
Worm |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.033
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.033
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.033
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.033
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.033
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.033
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.032
|
Fly |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.032
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.032
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.031
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.031
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.031
|
Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.031
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.031
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.031
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.031
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.030
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.030
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.030
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.030
|
Human |
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.030
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.030
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.030
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.030
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.029
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.029
|
Human |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.029
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.029
|
|
|
|
interleukin 12 mediated signaling pathway
|
GO:0035722 |
3 |
0.029
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.029
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.029
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.029
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.029
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.029
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.028
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.028
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.028
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.028
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.028
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.028
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.028
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.028
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.027
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.027
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.027
|
Human |
|
|
male genitalia development
|
GO:0030539 |
1 |
0.027
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.027
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.027
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.027
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.027
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.027
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.027
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.027
|
Fly |
|
|
metencephalon development
|
GO:0022037 |
2 |
0.027
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.027
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.026
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.026
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.026
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.026
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.026
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.026
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.026
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.026
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.026
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.026
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.025
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.025
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.025
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.025
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.025
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.025
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.025
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.025
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.025
|
|
|
|
cellular response to camp
|
GO:0071320 |
21 |
0.024
|
Human |
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.024
|
Mouse |
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.024
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.024
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.024
|
Fly |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.024
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.024
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.024
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.023
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.023
|
Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.023
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.023
|
|
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.023
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.023
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.023
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.022
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.022
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.022
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.022
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.022
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.022
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.022
|
|
|
|
neurotrophin signaling pathway
|
GO:0038179 |
8 |
0.022
|
Human |
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.022
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.022
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.022
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.021
|
Human Fly |
|
|
wound healing
|
GO:0042060 |
115 |
0.021
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.021
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.021
|
Mouse |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.021
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.021
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.021
|
Human |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.021
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.021
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.021
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.021
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.021
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.021
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
3 |
0.021
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.021
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.020
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.020
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.020
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.020
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.020
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.020
|
Human |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.020
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.020
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.020
|
Worm |
|
|
response to interleukin 13
|
GO:0035962 |
4 |
0.020
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.020
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.020
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.020
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.020
|
|
|
|
regulation of rap gtpase activity
|
GO:0032317 |
8 |
0.020
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.020
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.020
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.020
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.019
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.019
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.019
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.019
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.019
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.019
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.019
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.019
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.019
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.019
|
Fly |
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.019
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.018
|
|
|
|
female genitalia development
|
GO:0030540 |
2 |
0.018
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.018
|
Fly |
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.018
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.018
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.018
|
|
|
|
fc receptor signaling pathway
|
GO:0038093 |
2 |
0.018
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.018
|
Mouse |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.018
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.018
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.018
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.018
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.018
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.018
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.018
|
|
|
|
regulation of rap protein signal transduction
|
GO:0032487 |
9 |
0.018
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.018
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.017
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.017
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.017
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.017
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.017
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.017
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.017
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.017
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.017
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.017
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.017
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.017
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.017
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.017
|
Human Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.017
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.017
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.017
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.017
|
Worm |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.017
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.017
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.017
|
Human |
|
|
hemostasis
|
GO:0007599 |
76 |
0.017
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.016
|
|
|
|
lymphoid progenitor cell differentiation
|
GO:0002320 |
3 |
0.016
|
Mouse |
|
|
neuron death
|
GO:0070997 |
65 |
0.016
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.016
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.016
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.016
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.016
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.016
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.016
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.016
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.016
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.016
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.016
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.016
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
16 |
0.016
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.016
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.016
|
Fly |
|
|
t cell activation
|
GO:0042110 |
99 |
0.016
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.016
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.016
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.016
|
Mouse |
|
|
visual behavior
|
GO:0007632 |
2 |
0.015
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.015
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.015
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.015
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.015
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.015
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.015
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.015
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.015
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.015
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.015
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.015
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.015
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
11 |
0.015
|
|
|
|
pro b cell differentiation
|
GO:0002328 |
1 |
0.015
|
Mouse |
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.015
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.015
|
Fly |
|
|
cerebellum development
|
GO:0021549 |
2 |
0.015
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.015
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.015
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.015
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.015
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.015
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.015
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.015
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.015
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.015
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.015
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.014
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.014
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.014
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.014
|
|
