Homo sapiens

0 known processes

SPG21

spastic paraplegia 21 (autosomal recessive, Mast syndrome)

(Aliases: MASPARDIN,MAST,GL010,ACP33)

SPG21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cranial nerve development GO:0021545 4 0.976
negative regulation of axon extension GO:0030517 2 0.846
ribonucleotide biosynthetic process GO:0009260 81 0.811
endosome to lysosome transport GO:0008333 21 0.802
endoplasmic reticulum tubular network organization GO:0071786 8 0.550
vacuolar transport GO:0007034 34 0.536
nucleotide biosynthetic process GO:0009165 109 0.521
nucleoside phosphate biosynthetic process GO:1901293 109 0.489
lipid metabolic process GO:0006629 381 0.451
endoplasmic reticulum organization GO:0007029 20 0.407
cerebral cortex radially oriented cell migration GO:0021799 1 0.403
carbohydrate derivative biosynthetic process GO:1901137 207 0.391
phospholipid metabolic process GO:0006644 99 0.372
endosomal transport GO:0016197 129 0.347
negative regulation of cellular component organization GO:0051129 235 0.338
negative regulation of multicellular organismal process GO:0051241 317 0.335
single organism cellular localization GO:1902580 332 0.321
ribose phosphate biosynthetic process GO:0046390 82 0.305
nervous system development GO:0007399 293 0.295
positive regulation of protein localization to early endosome GO:1902966 2 0.292
optic nerve development GO:0021554 2 0.292
peripheral nervous system development GO:0007422 2 0.283
cerebral cortex cell migration GO:0021795 3 0.270
regulation of cell motility GO:2000145 299 0.263
mesenchymal cell development GO:0014031 50 0.245
organonitrogen compound biosynthetic process GO:1901566 200 0.244
mesenchyme development GO:0060485 59 0.238
neuropeptide signaling pathway GO:0007218 19 0.226
organophosphate biosynthetic process GO:0090407 163 0.218
nucleoside biosynthetic process GO:0009163 26 0.195
regulation of transferase activity GO:0051338 355 0.189
regulation of protein transport GO:0051223 213 0.188
negative regulation of axonogenesis GO:0050771 4 0.183
secretion by cell GO:0032940 226 0.181
regulation of cellular component movement GO:0051270 334 0.180
ribonucleoside triphosphate metabolic process GO:0009199 412 0.179
nucleoside triphosphate metabolic process GO:0009141 422 0.175
lipid biosynthetic process GO:0008610 177 0.167
negative regulation of cellular component movement GO:0051271 106 0.165
taxis GO:0042330 157 0.154
plasma membrane to endosome transport GO:0048227 6 0.151
mesenchymal cell differentiation GO:0048762 52 0.149
cellular lipid metabolic process GO:0044255 303 0.144
regulation of locomotion GO:0040012 329 0.144
vesicle organization GO:0016050 62 0.142
intracellular protein transport GO:0006886 270 0.140
negative regulation of transport GO:0051051 176 0.139
establishment of protein localization to organelle GO:0072594 172 0.139
regulation of nervous system development GO:0051960 88 0.133
negative regulation of nervous system development GO:0051961 28 0.125
carbohydrate transport GO:0008643 37 0.125
protein oligomerization GO:0051259 173 0.123
g protein coupled receptor signaling pathway GO:0007186 207 0.123
lysosomal transport GO:0007041 33 0.118
chemotaxis GO:0006935 157 0.116
cell development GO:0048468 328 0.115
ribonucleoside biosynthetic process GO:0042455 25 0.113
endomembrane system organization GO:0010256 196 0.112
positive regulation of cellular amine metabolic process GO:0033240 7 0.109
cerebral cortex development GO:0021987 10 0.107
cellular component morphogenesis GO:0032989 314 0.106
negative regulation of cellular amide metabolic process GO:0034249 3 0.105
negative regulation of protein metabolic process GO:0051248 391 0.104
nucleobase metabolic process GO:0009112 8 0.104
regulation of cellular component biogenesis GO:0044087 281 0.103
regulation of cell migration GO:0030334 289 0.099
purine nucleoside triphosphate metabolic process GO:0009144 412 0.097
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.097
glycosyl compound catabolic process GO:1901658 413 0.094
mitochondrion organization GO:0007005 156 0.090
enzyme linked receptor protein signaling pathway GO:0007167 303 0.089
purine ribonucleoside metabolic process GO:0046128 437 0.089
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.088
negative regulation of cell motility GO:2000146 104 0.087
generation of neurons GO:0048699 152 0.087
purine ribonucleotide biosynthetic process GO:0009152 79 0.086
cellular amine metabolic process GO:0044106 41 0.086
neurogenesis GO:0022008 169 0.084
glycosyl compound biosynthetic process GO:1901659 27 0.084
telencephalon cell migration GO:0022029 4 0.084
cellular amino acid metabolic process GO:0006520 116 0.083
positive regulation of intracellular protein transport GO:0090316 76 0.081
cation transport GO:0006812 331 0.081
apoptotic signaling pathway GO:0097190 268 0.081
negative regulation of catalytic activity GO:0043086 335 0.080
negative regulation of cellular protein metabolic process GO:0032269 353 0.079
cerebral cortex radial glia guided migration GO:0021801 1 0.079
maintenance of location in cell GO:0051651 62 0.079
positive regulation of transferase activity GO:0051347 227 0.078
epithelial to mesenchymal transition GO:0001837 48 0.077
positive regulation of protein catabolic process GO:0045732 75 0.076
regulation of anatomical structure morphogenesis GO:0022603 286 0.076
negative regulation of cell projection organization GO:0031345 22 0.075
sprouting angiogenesis GO:0002040 29 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.075
regulation of peptidase activity GO:0052547 180 0.073
metal ion transport GO:0030001 272 0.072
regulation of protein catabolic process GO:0042176 155 0.072
regulation of cell growth GO:0001558 135 0.072
female gamete generation GO:0007292 2 0.071
protein catabolic process GO:0030163 325 0.071
morphogenesis of a branching structure GO:0001763 21 0.070
regulation of protein maturation GO:1903317 150 0.069
pyrimidine ribonucleoside metabolic process GO:0046131 11 0.069
negative regulation of cell migration GO:0030336 102 0.069
regulation of cellular amino acid metabolic process GO:0006521 6 0.069
cell projection organization GO:0030030 252 0.068
maintenance of location GO:0051235 112 0.068
vacuole organization GO:0007033 44 0.068
regulation of cell differentiation GO:0045595 393 0.068
negative regulation of neurogenesis GO:0050768 26 0.067
cytoplasmic transport GO:0016482 379 0.067
protein localization to organelle GO:0033365 280 0.066
positive regulation of intracellular transport GO:0032388 104 0.066
regulation of proteolysis GO:0030162 293 0.066
regulation of cell development GO:0060284 161 0.065
signal transduction by phosphorylation GO:0023014 297 0.065
heart morphogenesis GO:0003007 48 0.064
response to oxygen containing compound GO:1901700 369 0.063
negative regulation of cell differentiation GO:0045596 171 0.062
inorganic cation transmembrane transport GO:0098662 194 0.061
regulation of establishment of protein localization GO:0070201 242 0.061
ras protein signal transduction GO:0007265 73 0.060
locomotory behavior GO:0007626 1 0.060
viral process GO:0016032 146 0.058
response to growth factor GO:0070848 205 0.057
lipid modification GO:0030258 84 0.057
regulation of intracellular transport GO:0032386 195 0.057
cation transmembrane transport GO:0098655 238 0.055
negative regulation of growth GO:0045926 97 0.055
ion transmembrane transport GO:0034220 338 0.055
cell morphogenesis GO:0000902 296 0.054
regulation of endopeptidase activity GO:0052548 170 0.053
rho protein signal transduction GO:0007266 26 0.053
regulation of cellular ketone metabolic process GO:0010565 50 0.053
response to nitrogen compound GO:1901698 184 0.052
cellular response to endogenous stimulus GO:0071495 336 0.051
guanosine containing compound catabolic process GO:1901069 239 0.051
negative regulation of cell growth GO:0030308 83 0.050
inorganic ion transmembrane transport GO:0098660 231 0.050
regulation of binding GO:0051098 111 0.050
organ morphogenesis GO:0009887 147 0.050
regulation of protein complex assembly GO:0043254 147 0.049
blood vessel development GO:0001568 172 0.049
associative learning GO:0008306 1 0.049
regulation of kinase activity GO:0043549 314 0.048
negative regulation of phosphate metabolic process GO:0045936 267 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.048
regulation of cellular amine metabolic process GO:0033238 11 0.048
interspecies interaction between organisms GO:0044419 156 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
response to external biotic stimulus GO:0043207 261 0.048
central nervous system development GO:0007417 123 0.047
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.047
neuromuscular junction development GO:0007528 3 0.047
positive regulation of protein transport GO:0051222 135 0.047
head development GO:0060322 108 0.047
ribonucleoside catabolic process GO:0042454 406 0.047
negative regulation of neuron differentiation GO:0045665 21 0.046
vasculature development GO:0001944 181 0.046
cell growth GO:0016049 160 0.046
amine metabolic process GO:0009308 44 0.046
vesicle mediated transport GO:0016192 371 0.046
regulation of anatomical structure size GO:0090066 101 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.045
regulation of mapk cascade GO:0043408 262 0.045
regulation of protein processing GO:0070613 150 0.045
purine ribonucleotide catabolic process GO:0009154 404 0.044
negative regulation of transferase activity GO:0051348 124 0.044
regulation of cytoskeleton organization GO:0051493 177 0.043
response to nerve growth factor GO:1990089 6 0.042
nerve growth factor signaling pathway GO:0038180 4 0.042
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.042
regulation of cellular component size GO:0032535 82 0.042
regulation of protein oligomerization GO:0032459 26 0.042
regulation of intracellular protein transport GO:0033157 123 0.042
negative regulation of protein complex assembly GO:0031333 43 0.041
negative regulation of developmental growth GO:0048640 10 0.041
cardiovascular system development GO:0072358 262 0.041
phospholipid biosynthetic process GO:0008654 44 0.041
neuron projection development GO:0031175 106 0.040
negative regulation of protein modification process GO:0031400 200 0.040
glucose import GO:0046323 24 0.040
nucleoside catabolic process GO:0009164 408 0.040
positive regulation of phosphorylation GO:0042327 394 0.040
carbohydrate metabolic process GO:0005975 207 0.039
ribonucleotide catabolic process GO:0009261 405 0.039
post embryonic development GO:0009791 2 0.038
extrinsic apoptotic signaling pathway GO:0097191 119 0.038
negative regulation of cell development GO:0010721 48 0.038
regulation of protein serine threonine kinase activity GO:0071900 179 0.038
regulation of protein kinase activity GO:0045859 289 0.038
cell part morphogenesis GO:0032990 137 0.037
gtp metabolic process GO:0046039 239 0.037
blastoderm segmentation GO:0007350 2 0.037
positive regulation of catabolic process GO:0009896 310 0.037
cellular ketone metabolic process GO:0042180 80 0.037
developmental cell growth GO:0048588 18 0.037
regulation of cytoplasmic transport GO:1903649 149 0.037
purine ribonucleoside catabolic process GO:0046130 398 0.037
small gtpase mediated signal transduction GO:0007264 78 0.037
positive regulation of proteolysis GO:0045862 142 0.036
angiogenesis GO:0001525 147 0.036
regulation of protein localization GO:0032880 296 0.036
limbic system development GO:0021761 3 0.036
regulation of protein localization to early endosome GO:1902965 2 0.036
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.036
negative regulation of endopeptidase activity GO:0010951 84 0.035
negative regulation of proteolysis GO:0045861 132 0.035
regulation of lipoprotein lipase activity GO:0051004 12 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
circulatory system development GO:0072359 262 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
endocytosis GO:0006897 159 0.034
regulation of neurogenesis GO:0050767 82 0.034
protein processing GO:0016485 226 0.034
positive regulation of cell cycle GO:0045787 140 0.034
regeneration GO:0031099 4 0.034
memory GO:0007613 3 0.034
protein targeting GO:0006605 187 0.033
purine containing compound biosynthetic process GO:0072522 88 0.033
monovalent inorganic cation transport GO:0015672 128 0.033
hexose transport GO:0008645 30 0.033
glycoprotein metabolic process GO:0009100 110 0.033
guanosine containing compound metabolic process GO:1901068 244 0.033
positive regulation of hydrolase activity GO:0051345 331 0.032
cellular potassium ion transport GO:0071804 60 0.032
secretion GO:0046903 254 0.032
positive regulation of cellular catabolic process GO:0031331 284 0.032
negative regulation of jun kinase activity GO:0043508 4 0.032
oogenesis GO:0048477 2 0.032
purine nucleotide biosynthetic process GO:0006164 84 0.032
negative regulation of hydrolase activity GO:0051346 182 0.032
brain development GO:0007420 97 0.031
negative regulation of protein transport GO:0051224 75 0.031
nucleoside triphosphate biosynthetic process GO:0009142 20 0.031
protein maturation GO:0051604 233 0.031
cellular macromolecule catabolic process GO:0044265 380 0.031
regulation of morphogenesis of a branching structure GO:0060688 6 0.031
negative regulation of mapk cascade GO:0043409 56 0.031
neuron differentiation GO:0030182 138 0.031
organophosphate catabolic process GO:0046434 430 0.031
maintenance of protein location GO:0045185 57 0.030
blood vessel morphogenesis GO:0048514 162 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.030
protein targeting to vacuole GO:0006623 8 0.030
regulation of ras gtpase activity GO:0032318 128 0.029
glycerophospholipid metabolic process GO:0006650 84 0.029
microtubule based process GO:0007017 210 0.029
regulation of growth GO:0040008 165 0.029
monosaccharide transport GO:0015749 32 0.029
negative regulation of smoothened signaling pathway GO:0045879 3 0.029
glycerolipid metabolic process GO:0046486 107 0.029
regulation of system process GO:0044057 101 0.028
growth GO:0040007 202 0.028
negative regulation of locomotion GO:0040013 118 0.028
neurotrophin trk receptor signaling pathway GO:0048011 4 0.028
stem cell development GO:0048864 69 0.028
membrane organization GO:0061024 292 0.028
dephosphorylation GO:0016311 209 0.028
negative regulation of binding GO:0051100 57 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
regulation of purine nucleotide catabolic process GO:0033121 205 0.028
negative regulation of protein oligomerization GO:0032460 8 0.028
system process GO:0003008 349 0.027
cellular response to oxygen containing compound GO:1901701 276 0.027
oxidation reduction process GO:0055114 396 0.026
mitochondrion distribution GO:0048311 3 0.026
positive regulation of cytoplasmic transport GO:1903651 82 0.026
protein dephosphorylation GO:0006470 81 0.026
defense response GO:0006952 315 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
regulation of protein binding GO:0043393 66 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
mapk cascade GO:0000165 288 0.026
glucose transport GO:0015758 30 0.026
cell morphogenesis involved in differentiation GO:0000904 144 0.025
response to hormone GO:0009725 175 0.025
protein localization to vacuole GO:0072665 11 0.025
single organism nuclear import GO:1902593 104 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
stem cell differentiation GO:0048863 93 0.024
cytokine production GO:0001816 247 0.024
response to abiotic stimulus GO:0009628 336 0.024
regulation of neuron projection development GO:0010975 57 0.024
mitochondrial membrane organization GO:0007006 40 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
single organism membrane organization GO:0044802 268 0.024
muscle cell migration GO:0014812 19 0.023
response to insulin GO:0032868 45 0.023
nucleocytoplasmic transport GO:0006913 176 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
neuron development GO:0048666 113 0.023
regulation of cell cycle GO:0051726 393 0.023
pyrimidine nucleoside metabolic process GO:0006213 13 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
positive regulation of camp biosynthetic process GO:0030819 35 0.023
regulation of cellular protein catabolic process GO:1903362 96 0.022
negative regulation of peptidase activity GO:0010466 91 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
intermediate filament based process GO:0045103 17 0.022
telencephalon development GO:0021537 17 0.022
potassium ion transport GO:0006813 62 0.022
oocyte differentiation GO:0009994 2 0.022
endocytic recycling GO:0032456 12 0.022
membrane lipid metabolic process GO:0006643 53 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
negative regulation of protein kinase activity GO:0006469 98 0.022
urate metabolic process GO:0046415 11 0.022
negative regulation of cardiac muscle cell differentiation GO:2000726 3 0.022
divalent inorganic cation transport GO:0072511 158 0.021
amyloid precursor protein metabolic process GO:0042982 17 0.021
cellular response to hormone stimulus GO:0032870 125 0.021
regulation of nucleotide catabolic process GO:0030811 205 0.021
glycoprotein biosynthetic process GO:0009101 91 0.021
cell chemotaxis GO:0060326 112 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
cell projection morphogenesis GO:0048858 129 0.021
amyloid precursor protein catabolic process GO:0042987 12 0.021
positive regulation of gtpase activity GO:0043547 166 0.021
regulation of cytokine production GO:0001817 232 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.021
multicellular organismal aging GO:0010259 3 0.020
negative regulation of protein processing GO:0010955 142 0.020
potassium ion transmembrane transport GO:0071805 60 0.020
pyrimidine containing compound metabolic process GO:0072527 19 0.020
camp metabolic process GO:0046058 61 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
forebrain development GO:0030900 26 0.020
cellular cation homeostasis GO:0030003 163 0.020
regulation of microtubule based process GO:0032886 74 0.020
pyrimidine nucleotide biosynthetic process GO:0006221 2 0.020
maintenance of protein location in cell GO:0032507 56 0.020
intermediate filament cytoskeleton organization GO:0045104 17 0.020
nerve development GO:0021675 4 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
innate immune response GO:0045087 178 0.020
second messenger mediated signaling GO:0019932 78 0.020
negative regulation of beta amyloid formation GO:1902430 3 0.019
gtp catabolic process GO:0006184 237 0.019
regulation of cellular response to stress GO:0080135 244 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
pyrimidine ribonucleoside triphosphate metabolic process GO:0009208 2 0.019
circadian sleep wake cycle sleep GO:0050802 2 0.019
negative regulation of calcium ion import GO:0090281 1 0.019
protein glycosylation GO:0006486 62 0.018
sensory organ development GO:0007423 52 0.018
activation of immune response GO:0002253 114 0.018
beta amyloid formation GO:0034205 7 0.018
cell projection assembly GO:0030031 126 0.018
regulation of secretion GO:0051046 194 0.018
actin cytoskeleton organization GO:0030036 207 0.018
oocyte development GO:0048599 1 0.018
negative regulation of protein phosphorylation GO:0001933 140 0.018
response to biotic stimulus GO:0009607 276 0.018
positive regulation of ras gtpase activity GO:0032320 117 0.018
lipid transport GO:0006869 90 0.018
chromatin modification GO:0016568 298 0.018
regulation of neuron differentiation GO:0045664 70 0.018
regulation of map kinase activity GO:0043405 108 0.018
regulation of response to external stimulus GO:0032101 222 0.018
organelle localization GO:0051640 84 0.018
response to peptide GO:1901652 65 0.017
negative regulation of intracellular transport GO:0032387 60 0.017
phosphatidylinositol metabolic process GO:0046488 53 0.017
regulation of calcium ion transport GO:0051924 79 0.017
regulation of transcription factor import into nucleus GO:0042990 39 0.017
mating GO:0007618 1 0.017
regulation of protein targeting GO:1903533 91 0.017
stress activated mapk cascade GO:0051403 93 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
mitotic cell cycle process GO:1903047 286 0.017
axon extension GO:0048675 13 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
establishment of protein localization to golgi GO:0072600 4 0.016
negative regulation of programmed cell death GO:0043069 321 0.016
circadian behavior GO:0048512 2 0.016
stress activated protein kinase signaling cascade GO:0031098 94 0.016
developmental growth involved in morphogenesis GO:0060560 23 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
somatic stem cell maintenance GO:0035019 4 0.016
adult locomotory behavior GO:0008344 1 0.016
post golgi vesicle mediated transport GO:0006892 36 0.016
cellular amide metabolic process GO:0043603 69 0.016
camp biosynthetic process GO:0006171 47 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
neuroblast proliferation GO:0007405 4 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
jnk cascade GO:0007254 80 0.015
negative regulation of kinase activity GO:0033673 106 0.015
defense response to virus GO:0051607 71 0.015
positive regulation of immune system process GO:0002684 283 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
spermatid differentiation GO:0048515 4 0.015
positive regulation of transport GO:0051050 336 0.015
regulation of neuron death GO:1901214 56 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
regulation of heart growth GO:0060420 4 0.015
negative regulation of protein binding GO:0032091 35 0.015
segmentation GO:0035282 4 0.015
negative regulation of developmental process GO:0051093 247 0.015
cyclic purine nucleotide metabolic process GO:0052652 60 0.015
camera type eye development GO:0043010 25 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.015
macromolecule glycosylation GO:0043413 63 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
methylation GO:0032259 106 0.015
mitotic cell cycle GO:0000278 326 0.015
rhythmic behavior GO:0007622 2 0.015
response to other organism GO:0051707 261 0.015
transcription factor import into nucleus GO:0042991 40 0.015
cellular response to biotic stimulus GO:0071216 71 0.015
response to organonitrogen compound GO:0010243 156 0.014
chemical homeostasis GO:0048878 306 0.014
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.014
positive regulation of protein complex assembly GO:0031334 86 0.014
determination of adult lifespan GO:0008340 2 0.014
regulation of microtubule cytoskeleton organization GO:0070507 61 0.014
protein localization to lysosome GO:0061462 11 0.014
leukocyte chemotaxis GO:0030595 76 0.014
positive regulation of apoptotic signaling pathway GO:2001235 70 0.014
divalent metal ion transport GO:0070838 152 0.014
regulation of rho protein signal transduction GO:0035023 79 0.014
cell cycle phase transition GO:0044770 173 0.014
negative regulation of secretion GO:0051048 58 0.014
nucleobase biosynthetic process GO:0046112 4 0.014
nuclear import GO:0051170 106 0.014
regulation of chromosome organization GO:0033044 103 0.014
golgi vesicle transport GO:0048193 80 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
spermatid development GO:0007286 4 0.014
myeloid leukocyte migration GO:0097529 62 0.014
immune effector process GO:0002252 159 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
peptide metabolic process GO:0006518 51 0.014
regulation of protein localization to nucleus GO:1900180 85 0.013
regulation of cardiac muscle tissue growth GO:0055021 4 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
neurological system process GO:0050877 163 0.013
regulation of cell projection organization GO:0031344 107 0.013
regulation of ion transport GO:0043269 189 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
response to inorganic substance GO:0010035 127 0.013
cellular protein complex assembly GO:0043623 188 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
regulation of jnk cascade GO:0046328 73 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
tube closure GO:0060606 3 0.013
intermediate filament organization GO:0045109 10 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 1 0.013
ion homeostasis GO:0050801 230 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
small molecule biosynthetic process GO:0044283 157 0.013
muscle system process GO:0003012 81 0.013
negative regulation of lipoprotein lipase activity GO:0051005 5 0.013
neuron projection extension GO:1990138 14 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
response to cytokine GO:0034097 232 0.013
protein ubiquitination GO:0016567 314 0.013
protein localization to nucleus GO:0034504 136 0.013
chromatin organization GO:0006325 351 0.012
negative regulation of cytoplasmic transport GO:1903650 46 0.012
neurotransmitter secretion GO:0007269 4 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.012
regulation of mitochondrion organization GO:0010821 54 0.012
generation of precursor metabolites and energy GO:0006091 68 0.012
sensory perception GO:0007600 103 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
nucleotide catabolic process GO:0009166 408 0.012
transmembrane transport GO:0055085 399 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
protein polymerization GO:0051258 71 0.012
negative regulation of cell proliferation GO:0008285 228 0.012

SPG21 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.109
nervous system disease DOID:863 431 0.109
sensory system disease DOID:0050155 203 0.080
neurodegenerative disease DOID:1289 102 0.031
auditory system disease DOID:2742 53 0.031
nonsyndromic deafness DOID:0050563 50 0.029
disease of mental health DOID:150 70 0.021
cognitive disorder DOID:1561 29 0.021
disease of metabolism DOID:0014667 295 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
organ system cancer DOID:0050686 164 0.018
neuropathy DOID:870 52 0.015
inherited metabolic disorder DOID:655 242 0.014
immune system disease DOID:2914 155 0.012