Homo sapiens

9 known processes

MSX2

msh homeobox 2

(Aliases: HOX8,PFM,CRS2,FPP,MSH,PFM1)

MSX2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
bmp signaling pathway involved in heart development GO:0061312 3 0.904
Mouse
embryonic forelimb morphogenesis GO:0035115 4 0.869
Mouse
forelimb morphogenesis GO:0035136 4 0.846
Mouse
regulation of odontogenesis GO:0042481 4 0.432
pituitary gland development GO:0021983 2 0.355
inner ear morphogenesis GO:0042472 4 0.320
anatomical structure formation involved in morphogenesis GO:0048646 284 0.236
Mouse
organ morphogenesis GO:0009887 147 0.235
Human Mouse Fly
hindlimb morphogenesis GO:0035137 2 0.222
Mouse
regulation of cell differentiation GO:0045595 393 0.205
Mouse Fly
ectodermal placode development GO:0071696 1 0.188
enzyme linked receptor protein signaling pathway GO:0007167 303 0.185
Mouse
skeletal system development GO:0001501 79 0.169
Mouse Rat
endocardial cushion development GO:0003197 3 0.165
Mouse
bmp signaling pathway GO:0030509 49 0.163
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.163
Mouse
cellular response to endogenous stimulus GO:0071495 336 0.153
Mouse
cellular component morphogenesis GO:0032989 314 0.152
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.148
Mouse
response to organic cyclic compound GO:0014070 204 0.148
Mouse
negative regulation of cell death GO:0060548 345 0.147
Mouse
bone development GO:0060348 26 0.143
Mouse
locomotory behavior GO:0007626 1 0.138
Worm
regulation of anatomical structure morphogenesis GO:0022603 286 0.135
positive regulation of developmental process GO:0051094 314 0.133
Mouse
embryonic hindlimb morphogenesis GO:0035116 2 0.132
Mouse
regulation of locomotion GO:0040012 329 0.131
epithelium development GO:0060429 227 0.131
Mouse
embryonic morphogenesis GO:0048598 85 0.130
Human Mouse Worm
positive regulation of cell proliferation GO:0008284 301 0.124
circulatory system development GO:0072359 262 0.124
Mouse
embryonic appendage morphogenesis GO:0035113 9 0.119
Human Mouse
oogenesis GO:0048477 2 0.118
Worm
cellular amino acid metabolic process GO:0006520 116 0.118
cardiac epithelial to mesenchymal transition GO:0060317 3 0.116
Mouse
positive regulation of programmed cell death GO:0043068 249 0.116
Human Mouse Rat
cell morphogenesis GO:0000902 296 0.116
Human Mouse
cell development GO:0048468 328 0.115
Mouse Rat Worm Fly
connective tissue development GO:0061448 39 0.114
Mouse Rat
female gamete generation GO:0007292 2 0.112
Worm
regulation of cellular amino acid metabolic process GO:0006521 6 0.109
odontogenesis GO:0042476 25 0.107
Human Mouse
nervous system development GO:0007399 293 0.107
Fly
regulation of cell motility GO:2000145 299 0.106
negative regulation of cell differentiation GO:0045596 171 0.106
Mouse
canonical wnt signaling pathway GO:0060070 116 0.105
negative regulation of multicellular organismal process GO:0051241 317 0.105
Mouse
negative regulation of cell proliferation GO:0008285 228 0.104
Mouse
negative regulation of programmed cell death GO:0043069 321 0.101
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.096
stem cell development GO:0048864 69 0.094
Mouse
regulation of cell cycle GO:0051726 393 0.093
Mouse
negative regulation of apoptotic process GO:0043066 316 0.091
Mouse
cellular ketone metabolic process GO:0042180 80 0.090
positive regulation of cellular amine metabolic process GO:0033240 7 0.090
cardiovascular system development GO:0072358 262 0.090
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.083
cellular response to organic cyclic compound GO:0071407 127 0.083
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.083
mesenchyme development GO:0060485 59 0.082
Mouse
nerve development GO:0021675 4 0.080
positive regulation of cell differentiation GO:0045597 211 0.080
Mouse
system process GO:0003008 349 0.077
negative regulation of developmental process GO:0051093 247 0.076
Mouse
endocrine system development GO:0035270 26 0.076
regulation of cell migration GO:0030334 289 0.073
regulation of apoptotic signaling pathway GO:2001233 175 0.072
Human
cellular amine metabolic process GO:0044106 41 0.071
sensory organ morphogenesis GO:0090596 21 0.070
post embryonic development GO:0009791 2 0.070
Fly
response to oxygen containing compound GO:1901700 369 0.070
Mouse
amine metabolic process GO:0009308 44 0.070
organ formation GO:0048645 3 0.068
regulation of growth GO:0040008 165 0.067
Human
signal transduction involved in regulation of gene expression GO:0023019 1 0.066
Mouse
mesenchymal cell differentiation GO:0048762 52 0.066
Mouse
ectodermal placode formation GO:0060788 1 0.066
neurogenesis GO:0022008 169 0.065
Fly
cell projection organization GO:0030030 252 0.065
apoptotic signaling pathway GO:0097190 268 0.065
Human
positive regulation of protein phosphorylation GO:0001934 313 0.065
epithelial cell differentiation GO:0030855 141 0.065
Mouse
epithelial to mesenchymal transition GO:0001837 48 0.064
Mouse
taxis GO:0042330 157 0.063
lipid metabolic process GO:0006629 381 0.063
positive regulation of meiotic cell cycle GO:0051446 2 0.063
Mouse
segmentation GO:0035282 4 0.062
cell morphogenesis involved in differentiation GO:0000904 144 0.061
Mouse
negative regulation of cell growth GO:0030308 83 0.060
Human
regulation of cell cycle process GO:0010564 266 0.060
Mouse
generation of neurons GO:0048699 152 0.059
skeletal system morphogenesis GO:0048705 24 0.059
Mouse
regulation of cellular component movement GO:0051270 334 0.059
embryonic organ morphogenesis GO:0048562 24 0.059
embryonic digit morphogenesis GO:0042733 6 0.057
Human Mouse
regulation of cell growth GO:0001558 135 0.057
Human
cell growth GO:0016049 160 0.057
Human
response to abiotic stimulus GO:0009628 336 0.056
small gtpase mediated signal transduction GO:0007264 78 0.055
response to growth factor GO:0070848 205 0.055
Mouse
forebrain generation of neurons GO:0021872 3 0.054
stem cell differentiation GO:0048863 93 0.054
Mouse
specification of organ identity GO:0010092 3 0.054
tissue morphogenesis GO:0048729 96 0.053
Mouse
positive regulation of transport GO:0051050 336 0.052
ectodermal placode morphogenesis GO:0071697 1 0.052
protein localization to organelle GO:0033365 280 0.052
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.051
Mouse
growth GO:0040007 202 0.050
Human Mouse
epithelial cell proliferation GO:0050673 128 0.050
regulation of meiosis GO:0040020 3 0.050
Mouse
positive regulation of organelle organization GO:0010638 195 0.049
Mouse
chemotaxis GO:0006935 157 0.049
positive regulation of ossification GO:0045778 32 0.049
Mouse
ameboidal type cell migration GO:0001667 135 0.049
heart development GO:0007507 95 0.048
Mouse
cell type specific apoptotic process GO:0097285 125 0.048
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
brain development GO:0007420 97 0.047
Fly
ras protein signal transduction GO:0007265 73 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.047
central nervous system development GO:0007417 123 0.046
Fly
regulation of canonical wnt signaling pathway GO:0060828 88 0.046
positive regulation of phosphorylation GO:0042327 394 0.046
limb morphogenesis GO:0035108 16 0.046
Human Mouse
signal transduction by phosphorylation GO:0023014 297 0.046
hindbrain development GO:0030902 3 0.045
cellular response to organonitrogen compound GO:0071417 124 0.045
regulation of binding GO:0051098 111 0.045
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.045
positive regulation of locomotion GO:0040017 186 0.045
tube development GO:0035295 125 0.045
Mouse
response to wounding GO:0009611 168 0.044
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.044
otic vesicle development GO:0071599 1 0.044
cell fate determination GO:0001709 3 0.044
response to organonitrogen compound GO:0010243 156 0.044
cranial nerve development GO:0021545 4 0.044
response to nitrogen compound GO:1901698 184 0.044
positive regulation of hydrolase activity GO:0051345 331 0.043
cellular response to nitrogen compound GO:1901699 144 0.043
regulation of transferase activity GO:0051338 355 0.043
cartilage development GO:0051216 31 0.042
Mouse Rat
positive regulation of apoptotic process GO:0043065 246 0.042
Human Mouse Rat
regulation of ossification GO:0030278 58 0.042
Mouse
positive regulation of immune system process GO:0002684 283 0.042
positive regulation of cellular component organization GO:0051130 376 0.041
Mouse
forebrain regionalization GO:0021871 3 0.041
actin filament based process GO:0030029 224 0.041
limbic system development GO:0021761 3 0.041
single organism cellular localization GO:1902580 332 0.041
positive regulation of cell migration GO:0030335 172 0.041
ossification GO:0001503 121 0.041
Mouse Rat
head development GO:0060322 108 0.041
Human Fly
positive regulation of apoptotic signaling pathway GO:2001235 70 0.040
Human
osteoblast differentiation GO:0001649 92 0.040
Mouse Rat
heart morphogenesis GO:0003007 48 0.040
Mouse
ear morphogenesis GO:0042471 7 0.040
regulation of protein localization GO:0032880 296 0.039
biological adhesion GO:0022610 331 0.039
neuron projection development GO:0031175 106 0.039
regulation of kinase activity GO:0043549 314 0.039
membrane organization GO:0061024 292 0.039
embryonic limb morphogenesis GO:0030326 9 0.039
Human Mouse
cellular response to oxygen containing compound GO:1901701 276 0.038
Mouse
regulation of organ morphogenesis GO:2000027 24 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
regulation of protein kinase activity GO:0045859 289 0.038
morphogenesis of an epithelium GO:0002009 60 0.038
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.038
determination of adult lifespan GO:0008340 2 0.037
transmembrane transport GO:0055085 399 0.037
blood vessel morphogenesis GO:0048514 162 0.037
parturition GO:0007567 1 0.037
Worm
multicellular organismal aging GO:0010259 3 0.036
regulation of mapk cascade GO:0043408 262 0.036
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
lipid biosynthetic process GO:0008610 177 0.035
neuron differentiation GO:0030182 138 0.035
secretion GO:0046903 254 0.035
negative regulation of growth GO:0045926 97 0.035
Human
organophosphate catabolic process GO:0046434 430 0.034
response to cytokine GO:0034097 232 0.034
secretion by cell GO:0032940 226 0.034
cytoplasmic transport GO:0016482 379 0.034
cell division GO:0051301 168 0.034
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.034
cell projection morphogenesis GO:0048858 129 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
pattern specification process GO:0007389 43 0.033
Mouse Fly
positive regulation of cell death GO:0010942 263 0.033
Human Mouse Rat
regulation of hormone levels GO:0010817 125 0.033
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.033
Mouse
epithelial cell migration GO:0010631 119 0.033
blood vessel development GO:0001568 172 0.033
positive regulation of cell motility GO:2000147 177 0.033
neuromuscular junction development GO:0007528 3 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
Human
cell adhesion GO:0007155 325 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
regulation of protein stability GO:0031647 87 0.032
Human
neuron development GO:0048666 113 0.032
positive regulation of epithelial cell proliferation GO:0050679 65 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
muscle structure development GO:0061061 98 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.032
embryonic organ development GO:0048568 36 0.031
protein catabolic process GO:0030163 325 0.031
regulation of proteolysis GO:0030162 293 0.031
cellular lipid metabolic process GO:0044255 303 0.031
ribonucleoside catabolic process GO:0042454 406 0.031
cell part morphogenesis GO:0032990 137 0.031
vesicle mediated transport GO:0016192 371 0.031
middle ear morphogenesis GO:0042474 1 0.031
vasculature development GO:0001944 181 0.031
immune system development GO:0002520 195 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.031
odontogenesis of dentin containing tooth GO:0042475 10 0.031
Human Mouse
cell activation GO:0001775 213 0.031
nucleotide catabolic process GO:0009166 408 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.030
positive regulation of protein kinase activity GO:0045860 190 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.030
embryo development GO:0009790 123 0.030
Human Mouse Worm
ribonucleoside triphosphate catabolic process GO:0009203 391 0.030
regulation of secretion GO:0051046 194 0.030
response to biotic stimulus GO:0009607 276 0.030
hemopoiesis GO:0030097 180 0.030
positive regulation of mapk cascade GO:0043410 190 0.030
regulation of intracellular transport GO:0032386 195 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
nucleoside catabolic process GO:0009164 408 0.030
purine containing compound catabolic process GO:0072523 411 0.029
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.029
anterior posterior axis specification GO:0009948 2 0.029
mapk cascade GO:0000165 288 0.029
reproductive process GO:0022414 106 0.029
Worm Fly
regulation of establishment of protein localization GO:0070201 242 0.029
wnt signaling pathway GO:0016055 156 0.029
response to hormone GO:0009725 175 0.029
Mouse
wound healing GO:0042060 115 0.029
Mouse
negative regulation of gliogenesis GO:0014014 3 0.029
cation transport GO:0006812 331 0.029
sex determination GO:0007530 3 0.029
intracellular protein transport GO:0006886 270 0.029
positive regulation of transferase activity GO:0051347 227 0.029
cytokine production GO:0001816 247 0.028
regulation of cytokine production GO:0001817 232 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
small molecule biosynthetic process GO:0044283 157 0.028
regulation of bmp signaling pathway GO:0030510 27 0.028
Mouse
embryonic epithelial tube formation GO:0001838 4 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
positive regulation of cell division GO:0051781 59 0.027
Mouse
forebrain neuron differentiation GO:0021879 3 0.027
digestive tract development GO:0048565 75 0.027
sensory organ development GO:0007423 52 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
positive regulation of tooth mineralization GO:0070172 2 0.027
cranial nerve morphogenesis GO:0021602 1 0.027
limb development GO:0060173 23 0.027
Human Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.027
single organism membrane organization GO:0044802 268 0.027
mitotic cell cycle GO:0000278 326 0.027
regulation of cell division GO:0051302 116 0.027
Mouse
compound eye development GO:0048749 1 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
oxidation reduction process GO:0055114 396 0.027
endochondral bone morphogenesis GO:0060350 3 0.027
Mouse
peripheral nervous system development GO:0007422 2 0.027
cartilage morphogenesis GO:0060536 1 0.027
regulation of peptidase activity GO:0052547 180 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.026
Mouse
negative regulation of transport GO:0051051 176 0.026
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
regulation of secretion by cell GO:1903530 177 0.026
regulation of cellular response to stress GO:0080135 244 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
protein stabilization GO:0050821 64 0.026
Human
regulation of osteoblast differentiation GO:0045667 38 0.026
Mouse
positive regulation of kinase activity GO:0033674 204 0.025
regeneration GO:0031099 4 0.025
ion homeostasis GO:0050801 230 0.025
neuroblast proliferation GO:0007405 4 0.025
thymus development GO:0048538 3 0.025
protein processing GO:0016485 226 0.025
positive regulation of cell cycle process GO:0090068 106 0.025
Mouse
neural crest cell development GO:0014032 3 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
positive regulation of catabolic process GO:0009896 310 0.025
mitotic cell cycle process GO:1903047 286 0.025
protein maturation GO:0051604 233 0.025
rho protein signal transduction GO:0007266 26 0.024
single organism reproductive process GO:0044702 98 0.024
Worm Fly
hair follicle morphogenesis GO:0031069 2 0.024
organelle fission GO:0048285 149 0.024
Mouse
positive regulation of protein transport GO:0051222 135 0.024
appendage development GO:0048736 23 0.024
Human Mouse Fly
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
response to lipid GO:0033993 206 0.024
Mouse
motor neuron axon guidance GO:0008045 2 0.024
positive regulation of odontogenesis GO:0042482 3 0.024
negative regulation of protein modification process GO:0031400 200 0.024
neurological system process GO:0050877 163 0.024
anion transport GO:0006820 161 0.024
ion transmembrane transport GO:0034220 338 0.024
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.023
Human
immune response GO:0006955 307 0.023
guanosine containing compound catabolic process GO:1901069 239 0.023
somitogenesis GO:0001756 2 0.023
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
nuclear division GO:0000280 128 0.023
Mouse
negative regulation of smoothened signaling pathway GO:0045879 3 0.023
blastoderm segmentation GO:0007350 2 0.023
cell cell signaling GO:0007267 155 0.023
regulation of synaptic plasticity GO:0048167 3 0.023
digestive system development GO:0055123 75 0.023
endodermal cell fate commitment GO:0001711 4 0.023
cell substrate adhesion GO:0031589 132 0.023
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.023
signal transduction by p53 class mediator GO:0072331 72 0.022
Human
nail development GO:0035878 3 0.022
Human Mouse
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of response to external stimulus GO:0032101 222 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
lung alveolus development GO:0048286 4 0.022
myeloid cell differentiation GO:0030099 117 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
positive regulation of bmp signaling pathway GO:0030513 9 0.022
Mouse
bone morphogenesis GO:0060349 10 0.022
Mouse
replacement ossification GO:0036075 1 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
heart formation GO:0060914 2 0.022
regulation of dna binding GO:0051101 37 0.022
Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
negative regulation of immune system process GO:0002683 136 0.022
forebrain development GO:0030900 26 0.022
midbrain development GO:0030901 45 0.022
protein localization to membrane GO:0072657 160 0.022
neural tube formation GO:0001841 3 0.022
protein ubiquitination GO:0016567 314 0.022
gtp catabolic process GO:0006184 237 0.022
leukocyte activation GO:0045321 164 0.022
adult locomotory behavior GO:0008344 1 0.021
regulation of epithelial cell migration GO:0010632 93 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
carbohydrate derivative biosynthetic process GO:1901137 207 0.021
positive regulation of proteolysis GO:0045862 142 0.021
chromatin organization GO:0006325 351 0.021
metal ion transport GO:0030001 272 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
Human
soft palate development GO:0060023 3 0.021
circadian behavior GO:0048512 2 0.021
carbohydrate metabolic process GO:0005975 207 0.021
tissue migration GO:0090130 119 0.021
chordate embryonic development GO:0043009 34 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
negative regulation of cell migration GO:0030336 102 0.021
negative regulation of muscle cell differentiation GO:0051148 17 0.021
cartilage condensation GO:0001502 1 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
memory GO:0007613 3 0.021
regulation of nuclear division GO:0051783 65 0.021
Mouse
regulation of nucleoside metabolic process GO:0009118 209 0.021
defense response GO:0006952 315 0.021
mesenchymal cell development GO:0014031 50 0.021
Mouse
epithelium migration GO:0090132 119 0.021
appendage morphogenesis GO:0035107 16 0.020
Human Mouse Fly
endomembrane system organization GO:0010256 196 0.020
muscle organ development GO:0007517 56 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
negative regulation of cell cycle GO:0045786 193 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
maintenance of location GO:0051235 112 0.020
neurotransmitter secretion GO:0007269 4 0.020
reactive oxygen species biosynthetic process GO:1903409 4 0.020
chemical homeostasis GO:0048878 306 0.020
epidermis morphogenesis GO:0048730 3 0.020
response to external biotic stimulus GO:0043207 261 0.020
tissue regeneration GO:0042246 3 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
anterior posterior axis specification embryo GO:0008595 2 0.020
dephosphorylation GO:0016311 209 0.020
endodermal cell fate specification GO:0001714 4 0.020
alcohol metabolic process GO:0006066 114 0.019
cellular protein catabolic process GO:0044257 261 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
endothelial cell migration GO:0043542 86 0.019
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.019
negative regulation of locomotion GO:0040013 118 0.019
regulation of protein transport GO:0051223 213 0.019
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
somatic stem cell maintenance GO:0035019 4 0.019
cellular macromolecular complex assembly GO:0034622 324 0.019
oocyte development GO:0048599 1 0.019
oocyte differentiation GO:0009994 2 0.019
spermatid differentiation GO:0048515 4 0.019
rhythmic behavior GO:0007622 2 0.019
positive regulation of synaptic transmission GO:0050806 4 0.019
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
primary neural tube formation GO:0014020 3 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
salivary gland morphogenesis GO:0007435 4 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
positive regulation of keratinocyte migration GO:0051549 4 0.019
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.018
metencephalon development GO:0022037 2 0.018
testosterone biosynthetic process GO:0061370 2 0.018
endochondral ossification GO:0001958 1 0.018
cation homeostasis GO:0055080 189 0.018
protein targeting GO:0006605 187 0.018
cellular homeostasis GO:0019725 196 0.018
cellular chemical homeostasis GO:0055082 180 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
regulation of cell development GO:0060284 161 0.018
ear development GO:0043583 14 0.018
positive regulation of neural precursor cell proliferation GO:2000179 2 0.018
embryonic viscerocranium morphogenesis GO:0048703 1 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
innate immune response GO:0045087 178 0.018
actin cytoskeleton organization GO:0030036 207 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.018
Human
cellular response to growth factor stimulus GO:0071363 197 0.018
Mouse
regulation of muscle cell differentiation GO:0051147 31 0.018
response to inorganic substance GO:0010035 127 0.018
catagen GO:0042637 3 0.018
Mouse
sensory perception GO:0007600 103 0.018
regulation of gtpase activity GO:0043087 180 0.017
carboxylic acid biosynthetic process GO:0046394 97 0.017
nitrogen compound transport GO:0071705 191 0.017
regulation of homeostatic process GO:0032844 121 0.017
single organism cell adhesion GO:0098602 179 0.017
somatic stem cell division GO:0048103 1 0.017
regulation of organ formation GO:0003156 4 0.017
angiogenesis GO:0001525 147 0.017
negative regulation of cell motility GO:2000146 104 0.017
regulation of protein maturation GO:1903317 150 0.017
muscle system process GO:0003012 81 0.017
embryonic camera type eye development GO:0031076 2 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
glycoprotein metabolic process GO:0009100 110 0.017
gland development GO:0048732 48 0.017
Mouse
regulation of neural precursor cell proliferation GO:2000177 4 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
positive regulation of cell cycle GO:0045787 140 0.017
Mouse
nuclear transport GO:0051169 179 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of immune response GO:0050776 201 0.017
circulatory system process GO:0003013 113 0.017
organic acid biosynthetic process GO:0016053 97 0.017
regulation of protein catabolic process GO:0042176 155 0.017
embryonic skeletal system development GO:0048706 13 0.017
gtp metabolic process GO:0046039 239 0.017
regulation of cell adhesion GO:0030155 166 0.017
muscle cell differentiation GO:0042692 63 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
hormone metabolic process GO:0042445 61 0.017

MSX2 disease predictions

Disease DO term ID Size Probability Func Analog Org
mouth disease DOID:403 14 0.122
Human
tooth disease DOID:1091 14 0.122
Human
gastrointestinal system disease DOID:77 36 0.122
Human
musculoskeletal system disease DOID:17 223 0.090
bone disease DOID:0080001 88 0.078
connective tissue disease DOID:65 109 0.078
bone development disease DOID:0080006 55 0.046
disease of metabolism DOID:0014667 295 0.029
inherited metabolic disorder DOID:655 242 0.025
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
osteochondrodysplasia DOID:2256 35 0.023
organ system cancer DOID:0050686 164 0.021
central nervous system disease DOID:331 186 0.020
physical disorder DOID:0080015 41 0.019
Human
syndrome DOID:225 17 0.019
Human
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.017