Homo sapiens

136 known processes

GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

(Aliases: TFB1,BTF2,TFIIH)

GTF2H1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 1.000
nucleotide excision repair GO:0006289 31 0.989
ribonucleoside monophosphate catabolic process GO:0009158 158 0.980
atp catabolic process GO:0006200 157 0.974
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.965
dna repair GO:0006281 198 0.938
atp metabolic process GO:0046034 176 0.932
nucleoside monophosphate catabolic process GO:0009125 159 0.919
purine nucleoside monophosphate metabolic process GO:0009126 186 0.913
nucleoside monophosphate metabolic process GO:0009123 191 0.909
nucleoside catabolic process GO:0009164 408 0.837
cellular response to dna damage stimulus GO:0006974 379 0.788
glycosyl compound catabolic process GO:1901658 413 0.747
nucleotide catabolic process GO:0009166 408 0.693
nucleotide excision repair dna incision GO:0033683 7 0.692
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.648
ribonucleoside catabolic process GO:0042454 406 0.617
dna templated transcription initiation GO:0006352 35 0.603
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.593
purine nucleoside catabolic process GO:0006152 398 0.574
nucleoside phosphate catabolic process GO:1901292 412 0.570
purine containing compound catabolic process GO:0072523 411 0.564
nucleoside triphosphate catabolic process GO:0009143 394 0.537
purine ribonucleotide catabolic process GO:0009154 404 0.507
purine nucleotide catabolic process GO:0006195 405 0.496
ribonucleotide catabolic process GO:0009261 405 0.483
mrna metabolic process GO:0016071 175 0.479
ribonucleoside monophosphate metabolic process GO:0009161 187 0.475
purine ribonucleoside metabolic process GO:0046128 437 0.450
organophosphate catabolic process GO:0046434 430 0.447
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.425
ribonucleoside triphosphate catabolic process GO:0009203 391 0.417
purine nucleoside triphosphate catabolic process GO:0009146 392 0.415
purine nucleoside monophosphate catabolic process GO:0009128 158 0.409
ribonucleoside triphosphate metabolic process GO:0009199 412 0.408
receptor mediated endocytosis GO:0006898 84 0.391
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.382
nucleoside triphosphate metabolic process GO:0009141 422 0.342
response to uv GO:0009411 73 0.324
regulation of dna metabolic process GO:0051052 153 0.314
transcription coupled nucleotide excision repair GO:0006283 8 0.261
endocytosis GO:0006897 159 0.260
Worm
response to abiotic stimulus GO:0009628 336 0.245
mitotic cell cycle phase transition GO:0044772 162 0.221
cell cycle phase transition GO:0044770 173 0.216
mitotic cell cycle process GO:1903047 286 0.201
mitotic cell cycle GO:0000278 326 0.193
epidermis development GO:0008544 59 0.190
regulation of cell cycle GO:0051726 393 0.185
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.184
rna processing GO:0006396 255 0.173
purine ribonucleoside catabolic process GO:0046130 398 0.160
negative regulation of cell cycle process GO:0010948 121 0.154
regulation of mitotic cell cycle phase transition GO:1901990 118 0.135
dna damage checkpoint GO:0000077 68 0.126
regulation of mitotic cell cycle GO:0007346 189 0.126
regulation of cell cycle process GO:0010564 266 0.121
receptor metabolic process GO:0043112 81 0.118
protein ubiquitination GO:0016567 314 0.111
modification dependent macromolecule catabolic process GO:0043632 212 0.108
mitotic nuclear division GO:0007067 119 0.102
amine metabolic process GO:0009308 44 0.099
female gamete generation GO:0007292 2 0.098
endomembrane system organization GO:0010256 196 0.098
vesicle mediated transport GO:0016192 371 0.094
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.092
oogenesis GO:0048477 2 0.085
dna integrity checkpoint GO:0031570 71 0.082
negative regulation of cell cycle GO:0045786 193 0.081
regulation of protein ubiquitination GO:0031396 95 0.077
7 methylguanosine mrna capping GO:0006370 7 0.074
mrna transport GO:0051028 30 0.074
response to radiation GO:0009314 151 0.074
cytoplasmic transport GO:0016482 379 0.071
ribonucleoprotein complex biogenesis GO:0022613 116 0.070
cellular amine metabolic process GO:0044106 41 0.070
cellular macromolecule catabolic process GO:0044265 380 0.068
mitotic dna damage checkpoint GO:0044773 28 0.067
reproductive process GO:0022414 106 0.064
Worm
transposition rna mediated GO:0032197 0 0.062
regulation of cell cycle phase transition GO:1901987 126 0.061
ubiquitin dependent protein catabolic process GO:0006511 206 0.061
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.056
neuron differentiation GO:0030182 138 0.052
multicellular organismal aging GO:0010259 3 0.052
epidermal cell differentiation GO:0009913 45 0.050
regulation of cellular response to stress GO:0080135 244 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.046
ribonucleoprotein complex subunit organization GO:0071826 81 0.046
positive regulation of cellular component organization GO:0051130 376 0.045
mitotic dna integrity checkpoint GO:0044774 30 0.045
cell cycle checkpoint GO:0000075 117 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
single organism membrane organization GO:0044802 268 0.044
intrinsic apoptotic signaling pathway GO:0097193 127 0.043
regulation of transposition GO:0010528 7 0.042
dna geometric change GO:0032392 32 0.042
positive regulation of catabolic process GO:0009896 310 0.042
determination of adult lifespan GO:0008340 2 0.042
negative regulation of programmed cell death GO:0043069 321 0.041
regulation of response to dna damage stimulus GO:2001020 94 0.041
epithelial cell differentiation GO:0030855 141 0.040
uv protection GO:0009650 5 0.039
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.038
double strand break repair GO:0006302 101 0.038
apoptotic signaling pathway GO:0097190 268 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
dna recombination GO:0006310 77 0.037
chromosome segregation GO:0007059 114 0.037
protein catabolic process GO:0030163 325 0.037
cellular amino acid metabolic process GO:0006520 116 0.035
mrna transcription GO:0009299 8 0.035
regulation of nuclear division GO:0051783 65 0.034
cellular component disassembly GO:0022411 92 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
macromolecule methylation GO:0043414 97 0.033
dna replication GO:0006260 116 0.032
cell growth GO:0016049 160 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.031
response to light stimulus GO:0009416 87 0.030
negative regulation of cell death GO:0060548 345 0.030
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.030
post embryonic development GO:0009791 2 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.029
nucleocytoplasmic transport GO:0006913 176 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.027
negative regulation of proteolysis GO:0045861 132 0.027
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.027
meiotic chromosome segregation GO:0045132 4 0.026
nuclear division GO:0000280 128 0.026
organelle fission GO:0048285 149 0.026
regulation of mrna processing GO:0050684 48 0.026
negative regulation of mitotic cell cycle GO:0045930 102 0.026
regulation of cell growth GO:0001558 135 0.026
negative regulation of apoptotic process GO:0043066 316 0.025
rna interference GO:0016246 4 0.025
negative regulation of cell cycle phase transition GO:1901988 89 0.025
positive regulation of transport GO:0051050 336 0.024
cell morphogenesis GO:0000902 296 0.024
positive regulation of cell death GO:0010942 263 0.024
regulation of gene expression epigenetic GO:0040029 73 0.024
regulation of protein kinase activity GO:0045859 289 0.024
maturation of ssu rrna GO:0030490 3 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
intracellular protein transport GO:0006886 270 0.023
sister chromatid segregation GO:0000819 54 0.023
dna duplex unwinding GO:0032508 30 0.023
nucleic acid transport GO:0050657 39 0.023
nucleobase containing compound transport GO:0015931 51 0.022
regulation of cell division GO:0051302 116 0.022
growth GO:0040007 202 0.022
macromolecular complex remodeling GO:0034367 16 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
negative regulation of catalytic activity GO:0043086 335 0.021
regulation of protein serine threonine kinase activity GO:0071900 179 0.021
cell projection organization GO:0030030 252 0.020
cellular component morphogenesis GO:0032989 314 0.020
nuclear export GO:0051168 69 0.020
cellular response to cytokine stimulus GO:0071345 181 0.019
cellular protein catabolic process GO:0044257 261 0.019
regulation of protein localization GO:0032880 296 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
lipid metabolic process GO:0006629 381 0.018
positive regulation of dna metabolic process GO:0051054 73 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
regulation of growth GO:0040008 165 0.018
negative regulation of protein metabolic process GO:0051248 391 0.018
meiosis i GO:0007127 4 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
positive regulation of growth GO:0045927 58 0.018
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.018
embryo development GO:0009790 123 0.018
Worm
ncrna processing GO:0034470 83 0.017
ncrna metabolic process GO:0034660 108 0.017
regulation of dna repair GO:0006282 47 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
positive regulation of developmental process GO:0051094 314 0.017
transmembrane transport GO:0055085 399 0.017
response to wounding GO:0009611 168 0.017
single organism cellular localization GO:1902580 332 0.017
negative regulation of cellular component organization GO:0051129 235 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
cytokine mediated signaling pathway GO:0019221 109 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
retrograde transport endosome to golgi GO:0042147 45 0.016
histone modification GO:0016570 251 0.016
rna capping GO:0036260 10 0.016
mrna processing GO:0006397 133 0.016
negative regulation of protein modification process GO:0031400 200 0.015
cellular response to radiation GO:0071478 65 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
cell division GO:0051301 168 0.015
vasculature development GO:0001944 181 0.015
response to other organism GO:0051707 261 0.015
regulation of chromosome organization GO:0033044 103 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.014
embryo development ending in birth or egg hatching GO:0009792 34 0.014
Worm
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.014
protein localization to nucleus GO:0034504 136 0.014
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
single organism reproductive process GO:0044702 98 0.014
Worm
secretion GO:0046903 254 0.014
recombinational repair GO:0000725 50 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
regulation of transferase activity GO:0051338 355 0.014
regulation of kinase activity GO:0043549 314 0.013
gene silencing GO:0016458 49 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
interspecies interaction between organisms GO:0044419 156 0.013
transcription from rna polymerase i promoter GO:0006360 11 0.013
nuclear transport GO:0051169 179 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
cellular lipid metabolic process GO:0044255 303 0.013
mrna splicing via spliceosome GO:0000398 89 0.013
cell fate determination GO:0001709 3 0.013
maintenance of location GO:0051235 112 0.013
regulation of protein transport GO:0051223 213 0.013
signal transduction by p53 class mediator GO:0072331 72 0.013
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.013
cellular ketone metabolic process GO:0042180 80 0.013
chromosome separation GO:0051304 23 0.013
methylation GO:0032259 106 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of proteolysis GO:0030162 293 0.012
lipid biosynthetic process GO:0008610 177 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
covalent chromatin modification GO:0016569 254 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
response to hypoxia GO:0001666 96 0.012
regulation of secretion GO:0051046 194 0.012
response to external biotic stimulus GO:0043207 261 0.012
regulation of protein stability GO:0031647 87 0.012
response to decreased oxygen levels GO:0036293 96 0.012
transposition GO:0032196 8 0.011
mitotic g2 m transition checkpoint GO:0044818 9 0.011
protein oligomerization GO:0051259 173 0.011
peptidyl lysine modification GO:0018205 144 0.011
response to inorganic substance GO:0010035 127 0.011
rna splicing GO:0008380 131 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
rna export from nucleus GO:0006405 33 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
protein secretion GO:0009306 98 0.011
reproductive system development GO:0061458 56 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
ion transmembrane transport GO:0034220 338 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
g protein coupled receptor internalization GO:0002031 6 0.011
positive regulation of secretion GO:0051047 116 0.011
cell part morphogenesis GO:0032990 137 0.010
regulation of intracellular transport GO:0032386 195 0.010
regulation of protein maturation GO:1903317 150 0.010
positive regulation of dna repair GO:0045739 25 0.010
protein maturation GO:0051604 233 0.010
neuromuscular junction development GO:0007528 3 0.010
defense response GO:0006952 315 0.010
7 methylguanosine rna capping GO:0009452 9 0.010
nucleus organization GO:0006997 28 0.010

GTF2H1 disease predictions

Disease DO term ID Size Probability Func Analog Org
xeroderma pigmentosum DOID:0050427 8 0.312
musculoskeletal system disease DOID:17 223 0.019
cancer DOID:162 167 0.011
disease of cellular proliferation DOID:14566 174 0.011