|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.805
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.721
|
Human Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.656
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.594
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.568
|
|
|
|
protein desumoylation
|
GO:0016926 |
4 |
0.554
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.532
|
|
|
|
regulation of definitive erythrocyte differentiation
|
GO:0010724 |
2 |
0.519
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.517
|
Human |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.504
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.487
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.426
|
Human Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.418
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.387
|
Human Mouse |
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.378
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.368
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.355
|
|
|
|
definitive erythrocyte differentiation
|
GO:0060318 |
2 |
0.351
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.351
|
Fly |
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.315
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.289
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.271
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.269
|
Human Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.265
|
|
|
|
regulation of rna stability
|
GO:0043487 |
23 |
0.243
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.242
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.237
|
Human Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.234
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.231
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.228
|
Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.227
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.226
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.215
|
Fly |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.194
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.193
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.189
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.185
|
Human Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.183
|
Human Mouse |
|
|
negative regulation of toll signaling pathway
|
GO:0045751 |
1 |
0.181
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.177
|
Fly |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.166
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.155
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.154
|
Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.150
|
Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.148
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.143
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
7 |
0.141
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.138
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.136
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.134
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.125
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.124
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.124
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.123
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.123
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.120
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.119
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.119
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.119
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.118
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.118
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.116
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.113
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.112
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.112
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.112
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.103
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.102
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.101
|
|
|
|
toll signaling pathway
|
GO:0008063 |
2 |
0.099
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.098
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.098
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.098
|
Human Mouse |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.096
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.095
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.095
|
Fly |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.094
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.090
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.088
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.088
|
Human Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.088
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.086
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.086
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.086
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.085
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.081
|
Human |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.081
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.081
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.079
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.079
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.077
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.075
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.075
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.074
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.074
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.074
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.073
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.073
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.072
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.071
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.071
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.069
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.069
|
|
|
|
proteoglycan catabolic process
|
GO:0030167 |
3 |
0.069
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.068
|
Human |
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.068
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.067
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.066
|
|
|
|
pml body organization
|
GO:0030578 |
2 |
0.066
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.066
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.066
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.065
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.065
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.064
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.062
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.062
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.062
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.062
|
Human Mouse |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.061
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.061
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.060
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.060
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.059
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.058
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.057
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.057
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.056
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.056
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.055
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.055
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.054
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.054
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.054
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.053
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.053
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.052
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.052
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.051
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.051
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.051
|
Human Mouse |
|
|
pharynx development
|
GO:0060465 |
1 |
0.050
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.049
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.048
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.048
|
Fly |
|
|
response to virus
|
GO:0009615 |
126 |
0.048
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.047
|
Zebrafish Fly |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.047
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.046
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.045
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.045
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.045
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.045
|
Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.044
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.043
|
Fly |
|
|
nuclear body organization
|
GO:0030575 |
4 |
0.043
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.043
|
Mouse Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.043
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.042
|
Human Mouse |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.042
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.041
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.041
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.041
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.041
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.041
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.040
|
Human Mouse |
|
|
keratinocyte apoptotic process
|
GO:0097283 |
1 |
0.040
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.040
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.039
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.039
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.039
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.039
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.039
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.038
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.038
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.038
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.037
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.037
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.037
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.037
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.036
|
Fly |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.036
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.036
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.036
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.036
|
Fly |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.036
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.035
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.035
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.035
|
|
|
|
system process
|
GO:0003008 |
349 |
0.035
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.034
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.034
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.034
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.034
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.033
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.033
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.033
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.033
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.033
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.033
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.033
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.032
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.032
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.032
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.032
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.032
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.032
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.031
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.031
|
Mouse |
|
|
nervous system development
|
GO:0007399 |
293 |
0.031
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.031
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.031
|
Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.031
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.031
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.031
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.030
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.030
|
Fly |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.030
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.030
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.030
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.029
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.029
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.029
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.029
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.029
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.029
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.029
|
Fly |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.029
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.028
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.028
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.028
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.028
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.028
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.028
|
|
|
|
head development
|
GO:0060322 |
108 |
0.028
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.028
|
Mouse |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.028
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.027
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.027
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.027
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.027
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.027
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.027
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.027
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.027
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.026
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.026
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.026
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.026
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.026
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.025
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
22 |
0.025
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.025
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.025
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.025
|
Fly |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.025
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.025
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.025
|
Human Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.025
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.025
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.024
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.024
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.024
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.024
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.024
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.024
|
|
|
|
aging
|
GO:0007568 |
66 |
0.024
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.024
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.024
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.024
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.024
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.024
|
Fly |
|
|
regulation of striated muscle contraction
|
GO:0006942 |
37 |
0.024
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.023
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.023
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.023
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.023
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.023
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.022
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.022
|
Fly |
|
|
protein acetylation
|
GO:0006473 |
116 |
0.022
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.022
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.022
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.022
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.021
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.021
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.021
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.021
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.021
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.021
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.020
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.020
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.020
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.020
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.020
|
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
28 |
0.020
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.020
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.020
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.020
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.020
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.019
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.019
|
Human Mouse |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.019
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.019
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.019
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.019
|
|
|
|
3 utr mediated mrna stabilization
|
GO:0070935 |
8 |
0.019
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.019
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.019
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.019
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.019
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.019
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.018
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.018
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.018
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.018
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.018
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.018
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.018
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.018
|
Fly |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.018
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.018
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.018
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.018
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.018
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.018
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.018
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.018
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.017
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.017
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.017
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.017
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.017
|
Fly |
|
|
central nervous system neuron differentiation
|
GO:0021953 |
9 |
0.017
|
Fly |
|
|
positive regulation of calcium ion transmembrane transporter activity
|
GO:1901021 |
13 |
0.017
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.017
|
|
|
|
regulation of interleukin 1 mediated signaling pathway
|
GO:2000659 |
3 |
0.017
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.017
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.017
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.017
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.016
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.016
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.016
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.016
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.016
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.016
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.016
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.016
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.016
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.016
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.016
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.016
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.015
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.015
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.015
|
Fly |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.015
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.015
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.015
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.015
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.015
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.015
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.015
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.015
|
Fly |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.015
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.015
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.015
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.014
|
|
|
|
regulation of cardiac muscle cell contraction
|
GO:0086004 |
23 |
0.014
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.014
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.014
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.014
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.014
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.014
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.014
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.014
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.014
|
Fly |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.014
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.014
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.013
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.013
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.013
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.013
|
Fly |
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.013
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.013
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.013
|
Fly |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.013
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.013
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.013
|
Fly |
|
|
positive regulation of keratinocyte apoptotic process
|
GO:1902174 |
1 |
0.013
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.013
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.013
|
|
|
|
regulation of keratinocyte apoptotic process
|
GO:1902172 |
1 |
0.013
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.012
|
|
|
|
regulation of calcium transporting atpase activity
|
GO:1901894 |
3 |
0.012
|
|
|
|
dendritic spine organization
|
GO:0097061 |
4 |
0.012
|
Fly |
|
|
protein secretion
|
GO:0009306 |
98 |
0.012
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.012
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.012
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.012
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.012
|
|
|
|
negative regulation of histone phosphorylation
|
GO:0033128 |
2 |
0.012
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.012
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.012
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.012
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.012
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.012
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.012
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.012
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.012
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.012
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.012
|
|
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.012
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.012
|
Fly |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.012
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.012
|
Fly |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.011
|
Human |
|
|
protein complex localization
|
GO:0031503 |
31 |
0.011
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.011
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.011
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.011
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.011
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.011
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.011
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.011
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.011
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.011
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.011
|
|
|
|
negative regulation of hepatocyte growth factor receptor signaling pathway
|
GO:1902203 |
1 |
0.011
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.011
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.011
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.011
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.011
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.011
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.011
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.011
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.010
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.010
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.010
|
Fly |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.010
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.010
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.010
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.010
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.010
|
|
