Homo sapiens

0 known processes

UBE4A

ubiquitination factor E4A (UFD2 homolog, yeast)

(Aliases: E4,UBOX2,UFD2,MGC133315,KIAA0126)

UBE4A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.191
protein polyubiquitination GO:0000209 110 0.143
embryonic epithelial tube formation GO:0001838 4 0.139
cellular macromolecule catabolic process GO:0044265 380 0.103
Human
protein ubiquitination GO:0016567 314 0.101
response to biotic stimulus GO:0009607 276 0.096
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.076
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.075
cellular protein catabolic process GO:0044257 261 0.069
Human
ras protein signal transduction GO:0007265 73 0.069
cytoplasmic transport GO:0016482 379 0.065
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.060
regulation of protein localization GO:0032880 296 0.059
regulation of viral process GO:0050792 103 0.058
regulation of cell cycle GO:0051726 393 0.055
innate immune response GO:0045087 178 0.054
response to bacterium GO:0009617 144 0.053
modification dependent protein catabolic process GO:0019941 209 0.052
Human
cerebellum development GO:0021549 2 0.051
vesicle mediated transport GO:0016192 371 0.050
interspecies interaction between organisms GO:0044419 156 0.050
transmembrane transport GO:0055085 399 0.049
enzyme linked receptor protein signaling pathway GO:0007167 303 0.047
female gamete generation GO:0007292 2 0.047
modification dependent macromolecule catabolic process GO:0043632 212 0.046
Human
cellular response to dna damage stimulus GO:0006974 379 0.045
response to external biotic stimulus GO:0043207 261 0.045
immune response GO:0006955 307 0.044
lipid metabolic process GO:0006629 381 0.044
immune effector process GO:0002252 159 0.044
cellular macromolecular complex assembly GO:0034622 324 0.043
secretion GO:0046903 254 0.043
post embryonic development GO:0009791 2 0.042
positive regulation of immune system process GO:0002684 283 0.041
positive regulation of cellular component organization GO:0051130 376 0.040
cation transport GO:0006812 331 0.040
chemical homeostasis GO:0048878 306 0.040
protein catabolic process GO:0030163 325 0.040
Human
positive regulation of intracellular protein transport GO:0090316 76 0.039
apoptotic signaling pathway GO:0097190 268 0.038
Human
regulation of protein ubiquitination GO:0031396 95 0.038
cellular response to growth factor stimulus GO:0071363 197 0.038
primary neural tube formation GO:0014020 3 0.037
protein maturation GO:0051604 233 0.037
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.036
defense response GO:0006952 315 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.036
i kappab kinase nf kappab signaling GO:0007249 166 0.035
response to other organism GO:0051707 261 0.035
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.035
monovalent inorganic cation transport GO:0015672 128 0.034
regulation of multi organism process GO:0043900 157 0.034
protein processing GO:0016485 226 0.034
hindbrain development GO:0030902 3 0.033
cell development GO:0048468 328 0.032
metencephalon development GO:0022037 2 0.032
dna repair GO:0006281 198 0.031
rna processing GO:0006396 255 0.030
neuromuscular junction development GO:0007528 3 0.030
viral life cycle GO:0019058 132 0.030
cellular lipid metabolic process GO:0044255 303 0.029
microtubule based process GO:0007017 210 0.029
ion transmembrane transport GO:0034220 338 0.029
inorganic ion transmembrane transport GO:0098660 231 0.029
negative regulation of cell death GO:0060548 345 0.029
hydrogen transport GO:0006818 23 0.028
metal ion transport GO:0030001 272 0.028
system process GO:0003008 349 0.028
intracellular protein transport GO:0006886 270 0.027
golgi vesicle transport GO:0048193 80 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.027
oogenesis GO:0048477 2 0.027
negative regulation of cell cycle GO:0045786 193 0.027
spermatid differentiation GO:0048515 4 0.026
response to growth factor GO:0070848 205 0.026
inorganic cation transmembrane transport GO:0098662 194 0.026
regulation of proteolysis GO:0030162 293 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.026
cation transmembrane transport GO:0098655 238 0.026
single organism cellular localization GO:1902580 332 0.026
negative regulation of programmed cell death GO:0043069 321 0.026
neural tube formation GO:0001841 3 0.026
viral process GO:0016032 146 0.025
cell cycle phase transition GO:0044770 173 0.025
regulation of protein transport GO:0051223 213 0.025
cellular amine metabolic process GO:0044106 41 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
regulation of intracellular transport GO:0032386 195 0.024
memory GO:0007613 3 0.024
regulation of cell cycle process GO:0010564 266 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
protein autoubiquitination GO:0051865 37 0.024
mitotic cell cycle GO:0000278 326 0.023
lipid localization GO:0010876 106 0.023
oocyte development GO:0048599 1 0.023
negative regulation of apoptotic process GO:0043066 316 0.022
positive regulation of immune response GO:0050778 159 0.022
positive regulation of transport GO:0051050 336 0.022
cellular protein complex assembly GO:0043623 188 0.022
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.022
amine metabolic process GO:0009308 44 0.022
cell division GO:0051301 168 0.022
positive regulation of protein transport GO:0051222 135 0.022
protein targeting GO:0006605 187 0.022
response to transforming growth factor beta GO:0071559 94 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.021
positive regulation of defense response GO:0031349 87 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
defense response to other organism GO:0098542 129 0.021
negative regulation of viral process GO:0048525 66 0.020
regulation of cellular response to stress GO:0080135 244 0.020
multicellular organismal aging GO:0010259 3 0.020
regulation of protein complex assembly GO:0043254 147 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
nervous system development GO:0007399 293 0.020
regulation of canonical wnt signaling pathway GO:0060828 88 0.020
spermatid development GO:0007286 4 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
actin filament based process GO:0030029 224 0.020
cellular ketone metabolic process GO:0042180 80 0.020
associative learning GO:0008306 1 0.019
embryo development GO:0009790 123 0.019
regulation of dna metabolic process GO:0051052 153 0.019
mitotic cell cycle process GO:1903047 286 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
response to oxygen containing compound GO:1901700 369 0.019
peroxisome organization GO:0007031 28 0.019
anion transport GO:0006820 161 0.019
response to abiotic stimulus GO:0009628 336 0.019
Human
negative regulation of catalytic activity GO:0043086 335 0.019
regulation of defense response GO:0031347 154 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
cell growth GO:0016049 160 0.019
ossification GO:0001503 121 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.018
membrane organization GO:0061024 292 0.018
regulation of protein maturation GO:1903317 150 0.018
single organism membrane organization GO:0044802 268 0.018
positive regulation of intracellular transport GO:0032388 104 0.018
receptor metabolic process GO:0043112 81 0.018
regulation of viral genome replication GO:0045069 48 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
nucleoside catabolic process GO:0009164 408 0.017
proton transport GO:0015992 22 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
lipid transport GO:0006869 90 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
tripartite regional subdivision GO:0007351 2 0.017
biological adhesion GO:0022610 331 0.017
viral genome replication GO:0019079 50 0.017
mitochondrion organization GO:0007005 156 0.016
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
tube closure GO:0060606 3 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
response to organic cyclic compound GO:0014070 204 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
regulation of membrane potential GO:0042391 95 0.016
endomembrane system organization GO:0010256 196 0.016
response to nitrogen compound GO:1901698 184 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
neurogenesis GO:0022008 169 0.016
lipid modification GO:0030258 84 0.016
organelle assembly GO:0070925 176 0.016
maintenance of location GO:0051235 112 0.016
atp metabolic process GO:0046034 176 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
cation homeostasis GO:0055080 189 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
determination of adult lifespan GO:0008340 2 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
neurological system process GO:0050877 163 0.015
tube morphogenesis GO:0035239 95 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
oocyte differentiation GO:0009994 2 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.015
organophosphate catabolic process GO:0046434 430 0.015
protein k48 linked ubiquitination GO:0070936 38 0.015
blastoderm segmentation GO:0007350 2 0.015
cellular homeostasis GO:0019725 196 0.015
single organism reproductive process GO:0044702 98 0.015
protein oligomerization GO:0051259 173 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
Human
late endosome to vacuole transport GO:0045324 2 0.014
metal ion homeostasis GO:0055065 169 0.014
regulation of immune effector process GO:0002697 91 0.014
secretion by cell GO:0032940 226 0.014
locomotory behavior GO:0007626 1 0.014
eosinophil activation GO:0043307 3 0.014
regulation of tumor necrosis factor production GO:0032680 43 0.014
peptide metabolic process GO:0006518 51 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
defense response to bacterium GO:0042742 63 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
positive regulation of organelle organization GO:0010638 195 0.014
ion homeostasis GO:0050801 230 0.014
negative regulation of protein k63 linked ubiquitination GO:1900045 4 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
negative regulation of extracellular matrix organization GO:1903054 3 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
response to salt stress GO:0009651 3 0.014
cell adhesion GO:0007155 325 0.014
regulation of cytoskeleton organization GO:0051493 177 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
multi organism cellular process GO:0044764 156 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
nucleotide catabolic process GO:0009166 408 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
regulation of response to external stimulus GO:0032101 222 0.013
response to virus GO:0009615 126 0.013
cellular amide metabolic process GO:0043603 69 0.013
response to dsrna GO:0043331 25 0.013
growth GO:0040007 202 0.013
cell projection organization GO:0030030 252 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
neural tube closure GO:0001843 3 0.013
wnt signaling pathway GO:0016055 156 0.013
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.013
purine containing compound catabolic process GO:0072523 411 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.012
regulation of locomotion GO:0040012 329 0.012
myosin filament assembly GO:0031034 2 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
negative regulation of developmental process GO:0051093 247 0.012
organelle localization GO:0051640 84 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
regulation of meiosis GO:0040020 3 0.012
potassium ion transport GO:0006813 62 0.012
dephosphorylation GO:0016311 209 0.012
cellular response to dsrna GO:0071359 19 0.012
intracellular receptor signaling pathway GO:0030522 104 0.012
regulation of rab protein signal transduction GO:0032483 39 0.012
limbic system development GO:0021761 3 0.012
actin cytoskeleton organization GO:0030036 207 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
response to uv GO:0009411 73 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
glycoprotein metabolic process GO:0009100 110 0.012
regulation of innate immune response GO:0045088 97 0.012
atp catabolic process GO:0006200 157 0.012
regulation of protein targeting GO:1903533 91 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
regulation of growth GO:0040008 165 0.012
alcohol metabolic process GO:0006066 114 0.012
negative regulation of organelle organization GO:0010639 126 0.012
negative regulation of transport GO:0051051 176 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
segmentation GO:0035282 4 0.011
regulation of cellular component movement GO:0051270 334 0.011
vesicle organization GO:0016050 62 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
nucleus localization GO:0051647 1 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.011
cell part morphogenesis GO:0032990 137 0.011
regulation of response to biotic stimulus GO:0002831 55 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
endosomal transport GO:0016197 129 0.011
regulation of chemokine production GO:0032642 31 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
Human
nucleoside phosphate catabolic process GO:1901292 412 0.011
mitotic cell cycle checkpoint GO:0007093 68 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.011
centrosome organization GO:0051297 58 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
positive regulation of catabolic process GO:0009896 310 0.011
transition metal ion homeostasis GO:0055076 31 0.011
long term memory GO:0007616 2 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.010
positive regulation of cell cycle GO:0045787 140 0.010
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
trophectodermal cell differentiation GO:0001829 3 0.010
negative regulation of proteolysis GO:0045861 132 0.010
nerve development GO:0021675 4 0.010
regulation of cell adhesion GO:0030155 166 0.010
regulation of cellular response to growth factor stimulus GO:0090287 76 0.010
tumor necrosis factor production GO:0032640 43 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
response to radiation GO:0009314 151 0.010
Human
cellular cation homeostasis GO:0030003 163 0.010
response to extracellular stimulus GO:0009991 85 0.010

UBE4A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.169
inherited metabolic disorder DOID:655 242 0.169
carbohydrate metabolic disorder DOID:2978 55 0.068
glycogen storage disease DOID:2747 10 0.026
glycogen metabolism disorder DOID:0050728 10 0.026
musculoskeletal system disease DOID:17 223 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
organ system cancer DOID:0050686 164 0.013
congenital disorder of glycosylation DOID:5212 26 0.012