Homo sapiens

55 known processes

HCN2

hyperpolarization activated cyclic nucleotide-gated potassium channel 2

(Aliases: HAC-1,BCNG2,BCNG-2)

HCN2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic ion transmembrane transport GO:0098660 231 0.359
transmembrane transport GO:0055085 399 0.338
cation transmembrane transport GO:0098655 238 0.290
cellular potassium ion transport GO:0071804 60 0.280
potassium ion transmembrane transport GO:0071805 60 0.235
ion transmembrane transport GO:0034220 338 0.218
inorganic cation transmembrane transport GO:0098662 194 0.204
regulation of ion transport GO:0043269 189 0.175
metal ion transport GO:0030001 272 0.142
neurological system process GO:0050877 163 0.141
Human
nervous system development GO:0007399 293 0.134
Rat
locomotory behavior GO:0007626 1 0.132
cell differentiation in spinal cord GO:0021515 1 0.131
potassium ion transport GO:0006813 62 0.117
regulation of transmembrane transport GO:0034762 139 0.114
system process GO:0003008 349 0.114
Human Rat
cation transport GO:0006812 331 0.095
forebrain generation of neurons GO:0021872 3 0.094
regulation of cell differentiation GO:0045595 393 0.088
sensory perception GO:0007600 103 0.085
Human
regulation of membrane potential GO:0042391 95 0.083
sodium ion transmembrane transport GO:0035725 59 0.080
sensory perception of light stimulus GO:0050953 35 0.080
Human
response to organic cyclic compound GO:0014070 204 0.074
hindbrain development GO:0030902 3 0.071
cellular response to endogenous stimulus GO:0071495 336 0.069
neuron differentiation GO:0030182 138 0.069
blood circulation GO:0008015 113 0.067
Human Rat
positive regulation of transport GO:0051050 336 0.066
positive regulation of acrosome reaction GO:2000344 4 0.063
cell development GO:0048468 328 0.063
cellular amino acid metabolic process GO:0006520 116 0.059
cellular response to cgmp GO:0071321 5 0.059
adult locomotory behavior GO:0008344 1 0.059
sodium ion transport GO:0006814 61 0.058
cell morphogenesis GO:0000902 296 0.058
generation of neurons GO:0048699 152 0.053
cellular ketone metabolic process GO:0042180 80 0.053
cation homeostasis GO:0055080 189 0.052
regulation of acrosome reaction GO:0060046 4 0.052
calcium ion transport GO:0006816 147 0.052
g protein coupled receptor signaling pathway GO:0007186 207 0.052
regulation of ion transmembrane transport GO:0034765 132 0.051
post embryonic development GO:0009791 2 0.051
regulation of cell motility GO:2000145 299 0.050
secretion by cell GO:0032940 226 0.050
regulation of kinase activity GO:0043549 314 0.049
cell projection organization GO:0030030 252 0.048
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.047
positive regulation of phosphorylation GO:0042327 394 0.046
positive regulation of developmental process GO:0051094 314 0.046
negative regulation of multicellular organismal process GO:0051241 317 0.046
positive regulation of secretion GO:0051047 116 0.045
chemical homeostasis GO:0048878 306 0.042
amine metabolic process GO:0009308 44 0.042
response to nitrogen compound GO:1901698 184 0.042
regulation of locomotion GO:0040012 329 0.041
cellular component morphogenesis GO:0032989 314 0.040
forebrain neuron differentiation GO:0021879 3 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.040
neurogenesis GO:0022008 169 0.040
regulation of secretion by cell GO:1903530 177 0.039
cytoplasmic transport GO:0016482 379 0.039
monovalent inorganic cation transport GO:0015672 128 0.039
central nervous system development GO:0007417 123 0.038
Rat
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
startle response GO:0001964 3 0.038
determination of adult lifespan GO:0008340 2 0.037
segmentation GO:0035282 4 0.037
positive regulation of cellular component organization GO:0051130 376 0.037
circulatory system process GO:0003013 113 0.037
Human Rat
secretion GO:0046903 254 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.037
cellular response to organic cyclic compound GO:0071407 127 0.036
single organism membrane organization GO:0044802 268 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
response to oxygen containing compound GO:1901700 369 0.036
memory GO:0007613 3 0.036
multicellular organismal aging GO:0010259 3 0.036
biological adhesion GO:0022610 331 0.036
gabaergic neuron differentiation GO:0097154 1 0.036
regulation of secretion GO:0051046 194 0.036
cell morphogenesis involved in differentiation GO:0000904 144 0.035
cellular divalent inorganic cation homeostasis GO:0072503 128 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
divalent inorganic cation transport GO:0072511 158 0.035
regulation of cell morphogenesis GO:0022604 153 0.034
metencephalon development GO:0022037 2 0.034
divalent metal ion transport GO:0070838 152 0.034
globus pallidus development GO:0021759 1 0.034
female gamete generation GO:0007292 2 0.033
oogenesis GO:0048477 2 0.033
neuron development GO:0048666 113 0.033
dephosphorylation GO:0016311 209 0.033
neuron fate commitment GO:0048663 2 0.032
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
regulation of protein kinase activity GO:0045859 289 0.032
protein oligomerization GO:0051259 173 0.032
photoreceptor cell differentiation GO:0046530 2 0.032
cellular calcium ion homeostasis GO:0006874 117 0.032
response to light stimulus GO:0009416 87 0.032
Human
metal ion homeostasis GO:0055065 169 0.032
response to organonitrogen compound GO:0010243 156 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.031
lipid metabolic process GO:0006629 381 0.031
neuron projection development GO:0031175 106 0.031
negative regulation of catalytic activity GO:0043086 335 0.031
response to radiation GO:0009314 151 0.031
Human
cellular cation homeostasis GO:0030003 163 0.031
positive regulation of protein phosphorylation GO:0001934 313 0.031
calcium ion homeostasis GO:0055074 122 0.031
cellular lipid metabolic process GO:0044255 303 0.031
visual perception GO:0007601 27 0.031
Human
oxidation reduction process GO:0055114 396 0.031
head development GO:0060322 108 0.030
Rat
morphogenesis of embryonic epithelium GO:0016331 4 0.030
regulation of apoptotic signaling pathway GO:2001233 175 0.030
cytokine production GO:0001816 247 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
regulation of cellular component movement GO:0051270 334 0.030
micturition GO:0060073 3 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
response to abiotic stimulus GO:0009628 336 0.029
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
spinal cord development GO:0021510 4 0.029
regulation of transferase activity GO:0051338 355 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
apoptotic signaling pathway GO:0097190 268 0.029
ion homeostasis GO:0050801 230 0.029
negative regulation of developmental process GO:0051093 247 0.029
regulation of protein localization GO:0032880 296 0.028
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.028
regulation of cell migration GO:0030334 289 0.028
forelimb morphogenesis GO:0035136 4 0.028
vesicle mediated transport GO:0016192 371 0.028
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.028
neurotransmitter secretion GO:0007269 4 0.028
cellular response to camp GO:0071320 21 0.028
regulation of cell cycle GO:0051726 393 0.028
negative regulation of cell death GO:0060548 345 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
cell adhesion GO:0007155 325 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
carbohydrate derivative biosynthetic process GO:1901137 207 0.027
positive regulation of transferase activity GO:0051347 227 0.027
regulation of neurogenesis GO:0050767 82 0.027
response to hypoxia GO:0001666 96 0.027
regulation of neuron differentiation GO:0045664 70 0.027
organonitrogen compound biosynthetic process GO:1901566 200 0.026
calcium ion transmembrane transport GO:0070588 76 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
motor neuron axon guidance GO:0008045 2 0.026
regeneration GO:0031099 4 0.026
detection of stimulus GO:0051606 85 0.026
Human
behavior GO:0007610 112 0.025
regulation of synaptic plasticity GO:0048167 3 0.025
cell cell signaling GO:0007267 155 0.025
cellular homeostasis GO:0019725 196 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
regulation of cellular response to stress GO:0080135 244 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
regulation of heart contraction GO:0008016 50 0.025
Human Rat
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
regulation of cell development GO:0060284 161 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
microtubule based process GO:0007017 210 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
neuroblast proliferation GO:0007405 4 0.024
protein catabolic process GO:0030163 325 0.024
peripheral nervous system development GO:0007422 2 0.024
neuromuscular junction development GO:0007528 3 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
guanosine containing compound metabolic process GO:1901068 244 0.024
mating GO:0007618 1 0.024
single organism cellular localization GO:1902580 332 0.023
cell projection morphogenesis GO:0048858 129 0.023
chromatin organization GO:0006325 351 0.023
regulation of system process GO:0044057 101 0.023
Human Rat
eye photoreceptor cell differentiation GO:0001754 2 0.023
positive regulation of protein kinase activity GO:0045860 190 0.023
respiratory gaseous exchange GO:0007585 3 0.023
positive regulation of apoptotic process GO:0043065 246 0.023
cellular chemical homeostasis GO:0055082 180 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
heart contraction GO:0060047 62 0.023
Human Rat
synaptic transmission involved in micturition GO:0060084 2 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.022
cardiac cell fate determination GO:0060913 3 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
cellular ion homeostasis GO:0006873 168 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
chromatin modification GO:0016568 298 0.022
cellular response to nitrogen compound GO:1901699 144 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
positive regulation of immune system process GO:0002684 283 0.022
positive regulation of catabolic process GO:0009896 310 0.022
cellular amine metabolic process GO:0044106 41 0.022
cell fate determination GO:0001709 3 0.022
purine containing compound catabolic process GO:0072523 411 0.022
reactive oxygen species biosynthetic process GO:1903409 4 0.022
endomembrane system organization GO:0010256 196 0.022
ras protein signal transduction GO:0007265 73 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
positive regulation of cell motility GO:2000147 177 0.022
sensory perception of pain GO:0019233 4 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
regulation of heart rate GO:0002027 38 0.021
Human
bmp signaling pathway involved in heart development GO:0061312 3 0.021
cell part morphogenesis GO:0032990 137 0.021
protein localization to organelle GO:0033365 280 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
organ formation GO:0048645 3 0.021
exocytosis GO:0006887 71 0.021
cytosolic calcium ion homeostasis GO:0051480 89 0.021
protein processing GO:0016485 226 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
forebrain neuron development GO:0021884 2 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
nucleoside catabolic process GO:0009164 408 0.021
regulation of blood circulation GO:1903522 59 0.021
Human Rat
response to decreased oxygen levels GO:0036293 96 0.021
cellular protein catabolic process GO:0044257 261 0.021
nerve development GO:0021675 4 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
small gtpase mediated signal transduction GO:0007264 78 0.020
mitotic cell cycle process GO:1903047 286 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
negative regulation of protein modification process GO:0031400 200 0.020
mapk cascade GO:0000165 288 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.020
regulation of postsynaptic membrane potential GO:0060078 1 0.020
response to growth factor GO:0070848 205 0.020
regulation of cell projection organization GO:0031344 107 0.020
gtp metabolic process GO:0046039 239 0.020
positive regulation of cell proliferation GO:0008284 301 0.020
carbohydrate metabolic process GO:0005975 207 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
lipid biosynthetic process GO:0008610 177 0.020
organ morphogenesis GO:0009887 147 0.020
small molecule biosynthetic process GO:0044283 157 0.020
regulation of proteolysis GO:0030162 293 0.020
brain development GO:0007420 97 0.019
Rat
protein maturation GO:0051604 233 0.019
regulation of nervous system development GO:0051960 88 0.019
epithelium development GO:0060429 227 0.019
actin filament based process GO:0030029 224 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
membrane organization GO:0061024 292 0.019
axon cargo transport GO:0008088 2 0.019
intracellular protein transport GO:0006886 270 0.019
organophosphate catabolic process GO:0046434 430 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
embryonic epithelial tube formation GO:0001838 4 0.019
cerebellum development GO:0021549 2 0.019
ventral spinal cord development GO:0021517 1 0.019
action potential GO:0001508 34 0.018
embryonic camera type eye development GO:0031076 2 0.018
limbic system development GO:0021761 3 0.018
positive regulation of cell death GO:0010942 263 0.018
regulation of calcium ion transport GO:0051924 79 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
regulation of protein transport GO:0051223 213 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
positive regulation of cell migration GO:0030335 172 0.018
mitotic cell cycle GO:0000278 326 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.018
skeletal system development GO:0001501 79 0.017
detection of visible light GO:0009584 11 0.017
Human
positive regulation of cellular catabolic process GO:0031331 284 0.017
specification of organ identity GO:0010092 3 0.017
dermatan sulfate proteoglycan biosynthetic process GO:0050651 4 0.017
circadian behavior GO:0048512 2 0.017
cardiac right ventricle morphogenesis GO:0003215 3 0.017
taxis GO:0042330 157 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of cell cycle process GO:0010564 266 0.017
inner ear morphogenesis GO:0042472 4 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
regulation of synaptic transmission dopaminergic GO:0032225 4 0.017
positive regulation of glucocorticoid secretion GO:2000851 4 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.017
cardiovascular system development GO:0072358 262 0.017
regulation of intracellular transport GO:0032386 195 0.017
response to wounding GO:0009611 168 0.016
anion transport GO:0006820 161 0.016
striated muscle contraction GO:0006941 52 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
oocyte development GO:0048599 1 0.016
gtp catabolic process GO:0006184 237 0.016
regulation of ureteric bud formation GO:0072106 1 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
positive regulation of ion transport GO:0043270 87 0.016
regulation of mapk cascade GO:0043408 262 0.016
positive regulation of hormone biosynthetic process GO:0046886 4 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
mesodermal cell fate specification GO:0007501 2 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
negative regulation of transport GO:0051051 176 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
covalent chromatin modification GO:0016569 254 0.016
positive regulation of gliogenesis GO:0014015 4 0.016
regulation of neuron projection development GO:0010975 57 0.016
cell growth GO:0016049 160 0.016
regulation of multi organism process GO:0043900 157 0.016
response to axon injury GO:0048678 1 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
positive regulation of locomotion GO:0040017 186 0.015
visual learning GO:0008542 1 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
regulation of cytokine production GO:0001817 232 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
regulation of gtpase activity GO:0043087 180 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
detection of abiotic stimulus GO:0009582 15 0.015
Human
single organism cell adhesion GO:0098602 179 0.015
multicellular organismal signaling GO:0035637 34 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
sleep GO:0030431 2 0.015
carboxylic acid transport GO:0046942 63 0.015
glutamate receptor signaling pathway GO:0007215 23 0.015
rhythmic behavior GO:0007622 2 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
heart process GO:0003015 62 0.015
Human Rat
regulation of nucleoside metabolic process GO:0009118 209 0.015
actin mediated cell contraction GO:0070252 12 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
nucleotide catabolic process GO:0009166 408 0.015
artery smooth muscle contraction GO:0014824 3 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
protein ubiquitination GO:0016567 314 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
anterior posterior axis specification GO:0009948 2 0.015
visual behavior GO:0007632 2 0.015
camera type eye photoreceptor cell differentiation GO:0060219 1 0.015
organic acid transport GO:0015849 65 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of metal ion transport GO:0010959 120 0.015
negative regulation of platelet aggregation GO:0090331 3 0.015
actin filament based movement GO:0030048 17 0.015
histone modification GO:0016570 251 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
receptor metabolic process GO:0043112 81 0.014
wnt signaling pathway GO:0016055 156 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
long term memory GO:0007616 2 0.014
regulation of response to external stimulus GO:0032101 222 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
forebrain regionalization GO:0021871 3 0.014
negative regulation of protein processing GO:0010955 142 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
synaptic transmission GO:0007268 61 0.014
protein targeting GO:0006605 187 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
regulation of glial cell differentiation GO:0045685 3 0.014
regulation of protein complex assembly GO:0043254 147 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.014
regulation of ion transmembrane transporter activity GO:0032412 72 0.014
glycoprotein metabolic process GO:0009100 110 0.014
mesonephric tubule formation GO:0072172 1 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
peptidyl serine modification GO:0018209 106 0.014
rna processing GO:0006396 255 0.014
regulation of protein maturation GO:1903317 150 0.014
associative learning GO:0008306 1 0.014
cell cycle phase transition GO:0044770 173 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
proteoglycan metabolic process GO:0006029 29 0.014
regulation of protein processing GO:0070613 150 0.014
neuron projection regeneration GO:0031102 1 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
oocyte differentiation GO:0009994 2 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
regulation of potassium ion export GO:1902302 1 0.014
nitrogen compound transport GO:0071705 191 0.014
vasculature development GO:0001944 181 0.014
regulation of neurotransmitter secretion GO:0046928 3 0.014
mitochondrion organization GO:0007005 156 0.014
response to purine containing compound GO:0014074 40 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
cellular amide metabolic process GO:0043603 69 0.013
negative regulation of kinase activity GO:0033673 106 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
negative regulation of transferase activity GO:0051348 124 0.013
axon regeneration GO:0031103 1 0.013
cell division GO:0051301 168 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
rab protein signal transduction GO:0032482 4 0.013
regulation of transmembrane transporter activity GO:0022898 74 0.013
purine nucleoside triphosphate catabolic process GO:0009146 392 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
innate immune response GO:0045087 178 0.013
regulation of dephosphorylation GO:0035303 96 0.013
opioid receptor signaling pathway GO:0038003 4 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
neuronal action potential GO:0019228 9 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
positive regulation of kinase activity GO:0033674 204 0.013
tripartite regional subdivision GO:0007351 2 0.013
regulation of homeostatic process GO:0032844 121 0.013
immune response GO:0006955 307 0.013
immune system development GO:0002520 195 0.013
positive regulation of cytokine production GO:0001819 167 0.013
cyclic nucleotide biosynthetic process GO:0009190 61 0.013
primary neural tube formation GO:0014020 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
cellular response to hypoxia GO:0071456 51 0.013
negative regulation of wnt protein secretion GO:0061358 1 0.013
protein localization to membrane GO:0072657 160 0.013
heart formation GO:0060914 2 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
neural tube formation GO:0001841 3 0.013
regulation of hormone levels GO:0010817 125 0.013
spermatid differentiation GO:0048515 4 0.012
membrane hyperpolarization GO:0060081 1 0.012
heart field specification GO:0003128 2 0.012
axis elongation GO:0003401 4 0.012
response to organophosphorus GO:0046683 41 0.012
response to oxygen levels GO:0070482 100 0.012
regulation of atrial cardiac muscle cell membrane repolarization GO:0060372 4 0.012
somatic stem cell division GO:0048103 1 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
fatty acid metabolic process GO:0006631 115 0.012
somitogenesis GO:0001756 2 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
regulation of binding GO:0051098 111 0.012
mesenchyme development GO:0060485 59 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
cell type specific apoptotic process GO:0097285 125 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
embryonic eye morphogenesis GO:0048048 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
phospholipid metabolic process GO:0006644 99 0.012
protein dephosphorylation GO:0006470 81 0.012
positive regulation of neural precursor cell proliferation GO:2000179 2 0.012
cell activation GO:0001775 213 0.012
retina homeostasis GO:0001895 42 0.012
Human
single organismal cell cell adhesion GO:0016337 148 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
negative regulation of jun kinase activity GO:0043508 4 0.012
negative regulation of amine transport GO:0051953 1 0.012

HCN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.052
central nervous system disease DOID:331 186 0.024
nervous system disease DOID:863 431 0.024
Human
inherited metabolic disorder DOID:655 242 0.023
sensory system disease DOID:0050155 203 0.021
Human
musculoskeletal system disease DOID:17 223 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
cardiovascular system disease DOID:1287 106 0.013
Human
brain disease DOID:936 73 0.013
neurodegenerative disease DOID:1289 102 0.013
organ system cancer DOID:0050686 164 0.013
eye and adnexa disease DOID:1492 150 0.013
Human
eye disease DOID:5614 149 0.013
Human
disease of mental health DOID:150 70 0.012
acquired metabolic disease DOID:0060158 58 0.012