Homo sapiens

17 known processes

SENP2

SUMO1/sentrin/SMT3 specific peptidase 2

(Aliases: AXAM2,KIAA1331,DKFZp762A2316,SMT3IP2)

SENP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 379 0.137
female gamete generation GO:0007292 2 0.101
protein localization to organelle GO:0033365 280 0.087
post embryonic development GO:0009791 2 0.086
positive regulation of catabolic process GO:0009896 310 0.083
nucleocytoplasmic transport GO:0006913 176 0.079
single organism cellular localization GO:1902580 332 0.077
regulation of cell differentiation GO:0045595 393 0.075
nervous system development GO:0007399 293 0.062
multicellular organismal aging GO:0010259 3 0.059
determination of adult lifespan GO:0008340 2 0.059
mitotic cell cycle GO:0000278 326 0.058
apoptotic signaling pathway GO:0097190 268 0.057
Human
nuclear transport GO:0051169 179 0.057
response to abiotic stimulus GO:0009628 336 0.056
oogenesis GO:0048477 2 0.054
negative regulation of developmental process GO:0051093 247 0.052
cellular lipid metabolic process GO:0044255 303 0.051
intracellular protein transport GO:0006886 270 0.050
negative regulation of cellular component organization GO:0051129 235 0.049
hematopoietic or lymphoid organ development GO:0048534 186 0.049
regulation of protein kinase activity GO:0045859 289 0.049
organelle localization GO:0051640 84 0.048
response to other organism GO:0051707 261 0.048
cellular macromolecule catabolic process GO:0044265 380 0.047
locomotory behavior GO:0007626 1 0.047
spermatid development GO:0007286 4 0.046
nucleoside triphosphate metabolic process GO:0009141 422 0.046
mitotic cell cycle process GO:1903047 286 0.044
positive regulation of transport GO:0051050 336 0.044
regulation of kinase activity GO:0043549 314 0.044
spermatid differentiation GO:0048515 4 0.044
rna interference GO:0016246 4 0.044
cell development GO:0048468 328 0.044
protein targeting GO:0006605 187 0.043
posttranscriptional regulation of gene expression GO:0010608 213 0.043
ras protein signal transduction GO:0007265 73 0.041
mitochondrion organization GO:0007005 156 0.041
regulation of cytoskeleton organization GO:0051493 177 0.041
regulation of protein localization GO:0032880 296 0.040
negative regulation of protein metabolic process GO:0051248 391 0.039
regulation of intracellular transport GO:0032386 195 0.039
response to biotic stimulus GO:0009607 276 0.038
chromosome segregation GO:0007059 114 0.037
mitotic cell cycle phase transition GO:0044772 162 0.037
neurogenesis GO:0022008 169 0.037
protein catabolic process GO:0030163 325 0.036
memory GO:0007613 3 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.035
regulation of organelle assembly GO:1902115 40 0.035
cellular response to dna damage stimulus GO:0006974 379 0.035
regulation of cell cycle GO:0051726 393 0.034
defense response GO:0006952 315 0.034
positive regulation of intracellular transport GO:0032388 104 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.032
purine ribonucleotide catabolic process GO:0009154 404 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
cellular component morphogenesis GO:0032989 314 0.031
neuron differentiation GO:0030182 138 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
regulation of response to external stimulus GO:0032101 222 0.031
glycosyl compound catabolic process GO:1901658 413 0.030
nuclear export GO:0051168 69 0.030
cell projection organization GO:0030030 252 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
establishment of protein localization to organelle GO:0072594 172 0.029
somitogenesis GO:0001756 2 0.029
cell morphogenesis GO:0000902 296 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
oocyte development GO:0048599 1 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
regulation of proteolysis GO:0030162 293 0.029
Human
cellular amine metabolic process GO:0044106 41 0.029
response to oxygen containing compound GO:1901700 369 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
regulation of cell cycle process GO:0010564 266 0.028
carbohydrate metabolic process GO:0005975 207 0.028
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
regulation of protein transport GO:0051223 213 0.027
protein ubiquitination GO:0016567 314 0.027
cell cycle phase transition GO:0044770 173 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
negative regulation of organelle organization GO:0010639 126 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
Human
positive regulation of protein kinase activity GO:0045860 190 0.027
rna processing GO:0006396 255 0.027
gtp catabolic process GO:0006184 237 0.026
amine metabolic process GO:0009308 44 0.026
system process GO:0003008 349 0.026
gtp metabolic process GO:0046039 239 0.026
peripheral nervous system development GO:0007422 2 0.026
regulation of nucleocytoplasmic transport GO:0046822 98 0.026
cellular amino acid metabolic process GO:0006520 116 0.025
vesicle mediated transport GO:0016192 371 0.025
cell cycle checkpoint GO:0000075 117 0.025
establishment of organelle localization GO:0051656 59 0.025
cellular ketone metabolic process GO:0042180 80 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
regulation of transferase activity GO:0051338 355 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
protein import GO:0017038 130 0.024
immune response GO:0006955 307 0.024
nitrogen compound transport GO:0071705 191 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
response to external biotic stimulus GO:0043207 261 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
carbohydrate derivative biosynthetic process GO:1901137 207 0.024
lipid metabolic process GO:0006629 381 0.024
protein import into nucleus GO:0006606 104 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.023
modification dependent protein catabolic process GO:0019941 209 0.023
nuclear import GO:0051170 106 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
regulation of protein catabolic process GO:0042176 155 0.022
peptidyl serine phosphorylation GO:0018105 101 0.022
cell projection assembly GO:0030031 126 0.022
immune system development GO:0002520 195 0.022
single organism membrane organization GO:0044802 268 0.022
protein maturation GO:0051604 233 0.022
Human
positive regulation of transferase activity GO:0051347 227 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
centrosome organization GO:0051297 58 0.022
hemopoiesis GO:0030097 180 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
translation GO:0006412 132 0.022
associative learning GO:0008306 1 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
nucleobase containing compound transport GO:0015931 51 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
actin filament based movement GO:0030048 17 0.021
central nervous system development GO:0007417 123 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
regulation of establishment of protein localization GO:0070201 242 0.020
regulation of cellular response to stress GO:0080135 244 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.020
regulation of map kinase activity GO:0043405 108 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
i kappab kinase nf kappab signaling GO:0007249 166 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
positive regulation of map kinase activity GO:0043406 80 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
organophosphate catabolic process GO:0046434 430 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
cilium organization GO:0044782 68 0.019
dna replication GO:0006260 116 0.019
cerebral cortex cell migration GO:0021795 3 0.019
negative regulation of cell cycle GO:0045786 193 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
protein localization to nucleus GO:0034504 136 0.019
segmentation GO:0035282 4 0.019
regulation of microtubule based process GO:0032886 74 0.019
positive regulation of kinase activity GO:0033674 204 0.019
rna export from nucleus GO:0006405 33 0.019
regulation of jnk cascade GO:0046328 73 0.019
membrane organization GO:0061024 292 0.019
meiotic chromosome segregation GO:0045132 4 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
organelle assembly GO:0070925 176 0.019
regulation of peptidase activity GO:0052547 180 0.018
Human
transmembrane transport GO:0055085 399 0.018
response to bacterium GO:0009617 144 0.018
mapk cascade GO:0000165 288 0.018
oocyte differentiation GO:0009994 2 0.018
regulation of stress activated mapk cascade GO:0032872 84 0.018
proteasomal protein catabolic process GO:0010498 176 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
dna repair GO:0006281 198 0.018
oxidation reduction process GO:0055114 396 0.018
endocytosis GO:0006897 159 0.018
actin mediated cell contraction GO:0070252 12 0.018
regulation of mapk cascade GO:0043408 262 0.018
rna splicing GO:0008380 131 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
response to virus GO:0009615 126 0.017
regulation of protein targeting GO:1903533 91 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
rhythmic behavior GO:0007622 2 0.017
lymphocyte activation GO:0046649 133 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
positive regulation of apoptotic signaling pathway GO:2001235 70 0.017
fatty acid metabolic process GO:0006631 115 0.017
regulation of defense response GO:0031347 154 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.017
Human
organonitrogen compound biosynthetic process GO:1901566 200 0.017
retina homeostasis GO:0001895 42 0.017
protein processing GO:0016485 226 0.017
Human
regulation of cell development GO:0060284 161 0.017
negative regulation of cell development GO:0010721 48 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
positive regulation of immune response GO:0050778 159 0.017
metal ion transport GO:0030001 272 0.017
dna recombination GO:0006310 77 0.017
regulation of dna metabolic process GO:0051052 153 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
phospholipid metabolic process GO:0006644 99 0.017
single organism nuclear import GO:1902593 104 0.016
circulatory system development GO:0072359 262 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
negative regulation of cytoskeleton organization GO:0051494 45 0.016
atp metabolic process GO:0046034 176 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
Human
double strand break repair GO:0006302 101 0.016
anatomical structure homeostasis GO:0060249 100 0.016
response to oxidative stress GO:0006979 121 0.016
leukocyte activation GO:0045321 164 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
negative regulation of cell death GO:0060548 345 0.016
anterior posterior axis specification GO:0009948 2 0.016
actin filament based process GO:0030029 224 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of immune response GO:0050776 201 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
cardiovascular system development GO:0072358 262 0.016
biological adhesion GO:0022610 331 0.016
cell activation GO:0001775 213 0.016
response to fungus GO:0009620 4 0.015
rna splicing via transesterification reactions GO:0000375 90 0.015
negative regulation of catabolic process GO:0009895 104 0.015
rna transport GO:0050658 39 0.015
response to radiation GO:0009314 151 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
blastoderm segmentation GO:0007350 2 0.015
circadian behavior GO:0048512 2 0.015
peptidyl serine modification GO:0018209 106 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
cellular protein catabolic process GO:0044257 261 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
Rat
microtubule cytoskeleton organization GO:0000226 176 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
reproductive process GO:0022414 106 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
microtubule based process GO:0007017 210 0.015
mitotic nuclear division GO:0007067 119 0.014
innate immune response GO:0045087 178 0.014
cell projection morphogenesis GO:0048858 129 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
short term memory GO:0007614 1 0.014
positive regulation of cell death GO:0010942 263 0.014
Human
maintenance of location GO:0051235 112 0.014
positive regulation of cytoplasmic transport GO:1903651 82 0.014
meiosis i GO:0007127 4 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
guanosine containing compound catabolic process GO:1901069 239 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
leukocyte differentiation GO:0002521 98 0.014
glycoprotein biosynthetic process GO:0009101 91 0.014
rna catabolic process GO:0006401 71 0.014
regulation of microtubule cytoskeleton organization GO:0070507 61 0.014
neuromuscular junction development GO:0007528 3 0.014
generation of neurons GO:0048699 152 0.014
inflammatory response GO:0006954 79 0.014
enzyme linked receptor protein signaling pathway GO:0007167 303 0.014
dendritic spine morphogenesis GO:0060997 3 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
Human
myoblast fusion GO:0007520 1 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
dephosphorylation GO:0016311 209 0.014
mrna splicing via spliceosome GO:0000398 89 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
cell fate determination GO:0001709 3 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
nucleotide catabolic process GO:0009166 408 0.013
neuroblast proliferation GO:0007405 4 0.013
ion transmembrane transport GO:0034220 338 0.013
epithelium migration GO:0090132 119 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
Human
response to wounding GO:0009611 168 0.013
jnk cascade GO:0007254 80 0.013
cell migration involved in gastrulation GO:0042074 1 0.013
positive regulation of immune system process GO:0002684 283 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
cell division GO:0051301 168 0.013
protein targeting to nucleus GO:0044744 104 0.013
cation transport GO:0006812 331 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
macromolecule glycosylation GO:0043413 63 0.013
defense response to other organism GO:0098542 129 0.013
mrna metabolic process GO:0016071 175 0.013
positive regulation of developmental process GO:0051094 314 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
compound eye development GO:0048749 1 0.013
cell part morphogenesis GO:0032990 137 0.013
response to lipid GO:0033993 206 0.013
visual learning GO:0008542 1 0.013
cell cycle g2 m phase transition GO:0044839 43 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
negative regulation of protein kinase activity GO:0006469 98 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of cellular component movement GO:0051270 334 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.012
Human
cation transmembrane transport GO:0098655 238 0.012
metal ion homeostasis GO:0055065 169 0.012
spindle checkpoint GO:0031577 26 0.012
lymphocyte homeostasis GO:0002260 4 0.012
endomembrane system organization GO:0010256 196 0.012
rho protein signal transduction GO:0007266 26 0.012
tissue homeostasis GO:0001894 63 0.012
regulation of chromosome organization GO:0033044 103 0.012
regulation of actin filament based process GO:0032970 141 0.012
lipid biosynthetic process GO:0008610 177 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of neuroblast proliferation GO:1902692 3 0.012
defense response to bacterium GO:0042742 63 0.012
positive regulation of proteolysis GO:0045862 142 0.012
Human
negative regulation of protein phosphorylation GO:0001933 140 0.012
regulation of binding GO:0051098 111 0.012
Rat
adult locomotory behavior GO:0008344 1 0.012
response to hormone GO:0009725 175 0.012
central nervous system neuron axonogenesis GO:0021955 3 0.012
negative regulation of neuron differentiation GO:0045665 21 0.012
posttranscriptional gene silencing GO:0016441 25 0.012
mitochondrion distribution GO:0048311 3 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
regulation of multi organism process GO:0043900 157 0.011
regulation of response to wounding GO:1903034 101 0.011
chromatin modification GO:0016568 298 0.011
positive regulation of organelle organization GO:0010638 195 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
microtubule bundle formation GO:0001578 15 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
cell adhesion GO:0007155 325 0.011
lymphocyte differentiation GO:0030098 35 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
organelle fission GO:0048285 149 0.011
cilium morphogenesis GO:0060271 75 0.011
ion homeostasis GO:0050801 230 0.011
regulation of nervous system development GO:0051960 88 0.011
single organism reproductive process GO:0044702 98 0.011
negative regulation of protein maturation GO:1903318 142 0.011
negative regulation of transferase activity GO:0051348 124 0.011
tripartite regional subdivision GO:0007351 2 0.011
brain development GO:0007420 97 0.011
positive regulation of nucleobase containing compound transport GO:0032241 1 0.011
negative regulation of protein processing GO:0010955 142 0.011
nucleoside catabolic process GO:0009164 408 0.011
establishment of nucleus localization GO:0040023 1 0.011
covalent chromatin modification GO:0016569 254 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of protein processing GO:0070613 150 0.011
glycerophospholipid metabolic process GO:0006650 84 0.011
ameboidal type cell migration GO:0001667 135 0.011
regulation of dephosphorylation GO:0035303 96 0.011
wnt signaling pathway GO:0016055 156 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
negative regulation of nervous system development GO:0051961 28 0.011
chromatin organization GO:0006325 351 0.011
defense response to fungus GO:0050832 4 0.011
visual behavior GO:0007632 2 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
neurotransmitter secretion GO:0007269 4 0.011
epithelial cell proliferation GO:0050673 128 0.011
regulation of ion transport GO:0043269 189 0.011
mating GO:0007618 1 0.011
negative regulation of protein transport GO:0051224 75 0.011
zymogen activation GO:0031638 70 0.010
Human
regulation of protein maturation GO:1903317 150 0.010
cellular homeostasis GO:0019725 196 0.010
positive regulation of intracellular protein transport GO:0090316 76 0.010
establishment of protein localization to mitochondrion GO:0072655 22 0.010
cerebral cortex radially oriented cell migration GO:0021799 1 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
phosphatidylinositol metabolic process GO:0046488 53 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
centrosome duplication GO:0051298 28 0.010
interspecies interaction between organisms GO:0044419 156 0.010
regulation of protein import into nucleus GO:0042306 78 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
cytokine production GO:0001816 247 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
centrosome cycle GO:0007098 32 0.010
positive regulation of jnk cascade GO:0046330 52 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
response to axon injury GO:0048678 1 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
recombinational repair GO:0000725 50 0.010
microtubule organizing center organization GO:0031023 62 0.010
pattern specification process GO:0007389 43 0.010
Rat

SENP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.034
inherited metabolic disorder DOID:655 242 0.034
physical disorder DOID:0080015 41 0.032
cancer DOID:162 167 0.032
disease of cellular proliferation DOID:14566 174 0.032
organ system cancer DOID:0050686 164 0.032
congenital nervous system abnormality DOID:2490 21 0.026
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
immune system disease DOID:2914 155 0.015
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
musculoskeletal system disease DOID:17 223 0.010