Homo sapiens

48 known processes

SAMM50

sorting and assembly machinery component 50 homolog (S. cerevisiae)

(Aliases: YNL026W,OMP85,FLJ99036,TRG-3,FLJ42905,SAM50,TOB55,FLJ35825)

SAMM50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside monophosphate metabolic process GO:0009123 191 0.555
organonitrogen compound biosynthetic process GO:1901566 200 0.426
purine ribonucleoside metabolic process GO:0046128 437 0.355
purine nucleoside triphosphate metabolic process GO:0009144 412 0.311
ribonucleoside monophosphate metabolic process GO:0009161 187 0.286
nucleoside triphosphate metabolic process GO:0009141 422 0.263
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.238
multicellular organismal aging GO:0010259 3 0.235
oxidation reduction process GO:0055114 396 0.219
purine containing compound biosynthetic process GO:0072522 88 0.213
ribonucleoside triphosphate metabolic process GO:0009199 412 0.184
purine nucleoside monophosphate metabolic process GO:0009126 186 0.178
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.149
determination of adult lifespan GO:0008340 2 0.146
purine ribonucleotide biosynthetic process GO:0009152 79 0.130
purine nucleotide biosynthetic process GO:0006164 84 0.127
post embryonic development GO:0009791 2 0.114
Worm
atp metabolic process GO:0046034 176 0.110
cell development GO:0048468 328 0.098
ribonucleotide biosynthetic process GO:0009260 81 0.089
atp synthesis coupled electron transport GO:0042773 4 0.087
ribose phosphate biosynthetic process GO:0046390 82 0.071
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.068
mitochondrial respiratory chain complex assembly GO:0033108 23 0.067
oogenesis GO:0048477 2 0.063
vesicle mediated transport GO:0016192 371 0.063
Worm
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.060
female gamete generation GO:0007292 2 0.059
purine nucleoside catabolic process GO:0006152 398 0.058
nucleoside phosphate biosynthetic process GO:1901293 109 0.057
energy derivation by oxidation of organic compounds GO:0015980 43 0.057
organophosphate biosynthetic process GO:0090407 163 0.053
purine ribonucleoside biosynthetic process GO:0046129 23 0.052
carbohydrate derivative biosynthetic process GO:1901137 207 0.049
growth GO:0040007 202 0.048
embryo development GO:0009790 123 0.047
Worm
cellular protein complex assembly GO:0043623 188 0.046
nervous system development GO:0007399 293 0.045
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.045
response to oxidative stress GO:0006979 121 0.043
negative regulation of cell proliferation GO:0008285 228 0.042
oxidative phosphorylation GO:0006119 10 0.041
single organism membrane organization GO:0044802 268 0.041
mitochondrial membrane organization GO:0007006 40 0.040
dicarboxylic acid metabolic process GO:0043648 29 0.040
cellular component morphogenesis GO:0032989 314 0.040
regulation of purine nucleotide metabolic process GO:1900542 264 0.039
receptor mediated endocytosis GO:0006898 84 0.039
Worm
endocytosis GO:0006897 159 0.038
Worm
nucleotide biosynthetic process GO:0009165 109 0.038
protein maturation GO:0051604 233 0.037
regulation of growth GO:0040008 165 0.037
nucleoside phosphate catabolic process GO:1901292 412 0.037
protein processing GO:0016485 226 0.036
system process GO:0003008 349 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
actin filament based process GO:0030029 224 0.035
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.035
membrane organization GO:0061024 292 0.034
spermatid development GO:0007286 4 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
negative regulation of cell death GO:0060548 345 0.032
cellular amino acid metabolic process GO:0006520 116 0.032
generation of precursor metabolites and energy GO:0006091 68 0.030
negative regulation of apoptotic signaling pathway GO:2001234 97 0.030
lipid localization GO:0010876 106 0.030
maintenance of location GO:0051235 112 0.030
electron transport chain GO:0022900 8 0.029
spermatid differentiation GO:0048515 4 0.029
locomotory behavior GO:0007626 1 0.028
glycosyl compound catabolic process GO:1901658 413 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
monovalent inorganic cation transport GO:0015672 128 0.028
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
nucleoside catabolic process GO:0009164 408 0.028
neurogenesis GO:0022008 169 0.028
neuromuscular junction development GO:0007528 3 0.027
cytoplasmic transport GO:0016482 379 0.027
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.027
ribonucleoside biosynthetic process GO:0042455 25 0.027
purine nucleoside biosynthetic process GO:0042451 23 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
regulation of proteolysis GO:0030162 293 0.026
hydrogen transport GO:0006818 23 0.026
anion transport GO:0006820 161 0.026
ion transmembrane transport GO:0034220 338 0.024
lipid catabolic process GO:0016042 84 0.024
nadh dehydrogenase complex assembly GO:0010257 16 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
regulation of cell differentiation GO:0045595 393 0.023
negative regulation of intracellular signal transduction GO:1902532 183 0.023
adult locomotory behavior GO:0008344 1 0.023
translation GO:0006412 132 0.023
myosin filament assembly GO:0031034 2 0.023
mitochondrion organization GO:0007005 156 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
nitrogen compound transport GO:0071705 191 0.023
single organism cellular localization GO:1902580 332 0.023
reactive oxygen species metabolic process GO:0072593 75 0.023
citrate metabolic process GO:0006101 2 0.022
neuroblast proliferation GO:0007405 4 0.022
cation transport GO:0006812 331 0.022
cation transmembrane transport GO:0098655 238 0.022
amine metabolic process GO:0009308 44 0.022
response to abiotic stimulus GO:0009628 336 0.022
apoptotic signaling pathway GO:0097190 268 0.021
positive regulation of developmental process GO:0051094 314 0.021
response to external biotic stimulus GO:0043207 261 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
epithelium development GO:0060429 227 0.021
nucleotide catabolic process GO:0009166 408 0.021
tricarboxylic acid cycle GO:0006099 4 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
organic anion transport GO:0015711 103 0.021
intracellular protein transport GO:0006886 270 0.020
single organism reproductive process GO:0044702 98 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
negative regulation of apoptotic process GO:0043066 316 0.019
reproductive process GO:0022414 106 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
organophosphate catabolic process GO:0046434 430 0.019
regulation of transferase activity GO:0051338 355 0.019
spinal cord development GO:0021510 4 0.019
glycosyl compound biosynthetic process GO:1901659 27 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
lipid metabolic process GO:0006629 381 0.019
organic acid catabolic process GO:0016054 71 0.018
mitochondrial respiratory chain complex i assembly GO:0032981 16 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
mitochondrial electron transport nadh to ubiquinone GO:0006120 2 0.018
response to wounding GO:0009611 168 0.018
response to drug GO:0042493 81 0.018
transmembrane transport GO:0055085 399 0.018
small molecule catabolic process GO:0044282 92 0.018
cell growth GO:0016049 160 0.018
negative regulation of developmental process GO:0051093 247 0.018
protein targeting GO:0006605 187 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
actin cytoskeleton organization GO:0030036 207 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
central nervous system development GO:0007417 123 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
ion homeostasis GO:0050801 230 0.017
metal ion homeostasis GO:0055065 169 0.017
positive regulation of catabolic process GO:0009896 310 0.017
nerve development GO:0021675 4 0.016
atp catabolic process GO:0006200 157 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
response to other organism GO:0051707 261 0.016
nucleoside monophosphate biosynthetic process GO:0009124 19 0.016
cellular amine metabolic process GO:0044106 41 0.016
mitotic cell cycle GO:0000278 326 0.016
protein catabolic process GO:0030163 325 0.016
cellular ketone metabolic process GO:0042180 80 0.016
positive regulation of apoptotic process GO:0043065 246 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
purine containing compound catabolic process GO:0072523 411 0.015
protein localization to organelle GO:0033365 280 0.015
cell cell signaling GO:0007267 155 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
carboxylic acid catabolic process GO:0046395 71 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
biological adhesion GO:0022610 331 0.015
negative regulation of growth GO:0045926 97 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
regeneration GO:0031099 4 0.015
protein oligomerization GO:0051259 173 0.015
nucleoside biosynthetic process GO:0009163 26 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
segmentation GO:0035282 4 0.015
establishment of protein localization to membrane GO:0090150 121 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
aspartate metabolic process GO:0006531 4 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
response to nitrogen compound GO:1901698 184 0.014
regulation of protein kinase activity GO:0045859 289 0.014
tissue morphogenesis GO:0048729 96 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
regulation of cell cycle process GO:0010564 266 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
negative regulation of cell growth GO:0030308 83 0.014
reproduction GO:0000003 63 0.014
Worm
cell adhesion GO:0007155 325 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
response to decreased oxygen levels GO:0036293 96 0.014
organelle fusion GO:0048284 36 0.014
cation homeostasis GO:0055080 189 0.014
substantia nigra development GO:0021762 45 0.013
muscle structure development GO:0061061 98 0.013
dephosphorylation GO:0016311 209 0.013
myosin filament organization GO:0031033 2 0.013
cellular macromolecule catabolic process GO:0044265 380 0.013
cell part morphogenesis GO:0032990 137 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
protein tetramerization GO:0051262 47 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
reproductive system development GO:0061458 56 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
response to oxygen levels GO:0070482 100 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
positive regulation of organelle organization GO:0010638 195 0.013
response to oxygen containing compound GO:1901700 369 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.013
Worm
negative regulation of neural precursor cell proliferation GO:2000178 1 0.013
membrane fusion GO:0061025 43 0.013
regulation of cell growth GO:0001558 135 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
aging GO:0007568 66 0.013
chemical homeostasis GO:0048878 306 0.013
rna interference GO:0016246 4 0.013
fatty acid metabolic process GO:0006631 115 0.012
microtubule based process GO:0007017 210 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
succinate metabolic process GO:0006105 1 0.012
cell division GO:0051301 168 0.012
positive regulation of proteolysis GO:0045862 142 0.012
cell morphogenesis GO:0000902 296 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.012
regulation of gtpase activity GO:0043087 180 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
response to endoplasmic reticulum stress GO:0034976 49 0.012
cellular ion homeostasis GO:0006873 168 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
secretion by cell GO:0032940 226 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
regulation of kinase activity GO:0043549 314 0.012
regulation of response to external stimulus GO:0032101 222 0.012
secretion GO:0046903 254 0.012
regulation of membrane potential GO:0042391 95 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of protein localization GO:0032880 296 0.012
positive regulation of cell death GO:0010942 263 0.012
mitotic cell cycle process GO:1903047 286 0.011
positive regulation of transport GO:0051050 336 0.011
single organism membrane fusion GO:0044801 37 0.011
cellular cation homeostasis GO:0030003 163 0.011
generation of neurons GO:0048699 152 0.011
negative regulation of cell cycle GO:0045786 193 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
cell cycle phase transition GO:0044770 173 0.011
metal ion transport GO:0030001 272 0.011
hindbrain development GO:0030902 3 0.011
alpha amino acid metabolic process GO:1901605 72 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
reproductive structure development GO:0048608 55 0.011
cellular lipid metabolic process GO:0044255 303 0.011
negative regulation of organelle organization GO:0010639 126 0.011
response to axon injury GO:0048678 1 0.011
cellular respiration GO:0045333 21 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
protein localization to membrane GO:0072657 160 0.011
cellular chemical homeostasis GO:0055082 180 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
organelle assembly GO:0070925 176 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
developmental process involved in reproduction GO:0003006 66 0.011
regulation of atp metabolic process GO:1903578 29 0.010
negative regulation of transferase activity GO:0051348 124 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
cofactor biosynthetic process GO:0051188 31 0.010
response to biotic stimulus GO:0009607 276 0.010
guanosine containing compound metabolic process GO:1901068 244 0.010
lipid transport GO:0006869 90 0.010
response to organic cyclic compound GO:0014070 204 0.010
head development GO:0060322 108 0.010
cellular protein catabolic process GO:0044257 261 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
regulation of protein transport GO:0051223 213 0.010
neuron differentiation GO:0030182 138 0.010
positive regulation of cellular catabolic process GO:0031331 284 0.010

SAMM50 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.726
inherited metabolic disorder DOID:655 242 0.726
leigh disease DOID:3652 16 0.374
mitochondrial metabolism disease DOID:700 29 0.374
myopathy DOID:423 104 0.073
muscular disease DOID:0080000 114 0.073
musculoskeletal system disease DOID:17 223 0.073
muscle tissue disease DOID:66 113 0.073
cancer DOID:162 167 0.066
disease of cellular proliferation DOID:14566 174 0.066
sensory system disease DOID:0050155 203 0.044
eye and adnexa disease DOID:1492 150 0.044
nervous system disease DOID:863 431 0.044
eye disease DOID:5614 149 0.044
organ system cancer DOID:0050686 164 0.042
cardiovascular system disease DOID:1287 106 0.028
heart disease DOID:114 68 0.027
cardiomyopathy DOID:0050700 50 0.027
central nervous system disease DOID:331 186 0.025
retinal disease DOID:5679 118 0.024
immune system disease DOID:2914 155 0.024
neurodegenerative disease DOID:1289 102 0.024
retinal degeneration DOID:8466 89 0.023
intrinsic cardiomyopathy DOID:0060036 50 0.013
retinitis pigmentosa DOID:10584 51 0.011