Homo sapiens

84 known processes

PLK2

polo-like kinase 2

(Aliases: SNK)

PLK2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 44 0.260
regulation of cellular ketone metabolic process GO:0010565 50 0.209
cellular amine metabolic process GO:0044106 41 0.207
epithelium development GO:0060429 227 0.174
cell development GO:0048468 328 0.158
Rat
regulation of cell differentiation GO:0045595 393 0.158
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.153
nervous system development GO:0007399 293 0.151
Rat
cell adhesion GO:0007155 325 0.140
regulation of cellular amine metabolic process GO:0033238 11 0.139
negative regulation of multicellular organismal process GO:0051241 317 0.138
Rat
post embryonic development GO:0009791 2 0.125
purine nucleoside catabolic process GO:0006152 398 0.124
biological adhesion GO:0022610 331 0.123
regulation of cellular amino acid metabolic process GO:0006521 6 0.122
cellular amino acid metabolic process GO:0006520 116 0.120
ras protein signal transduction GO:0007265 73 0.115
Rat
nucleoside catabolic process GO:0009164 408 0.108
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.108
cellular ketone metabolic process GO:0042180 80 0.107
circulatory system development GO:0072359 262 0.104
negative regulation of cell proliferation GO:0008285 228 0.103
response to growth factor GO:0070848 205 0.102
ribonucleotide catabolic process GO:0009261 405 0.099
negative regulation of catalytic activity GO:0043086 335 0.095
Human
regulation of locomotion GO:0040012 329 0.091
regulation of cell adhesion GO:0030155 166 0.088
negative regulation of cellular protein metabolic process GO:0032269 353 0.087
Human
negative regulation of cell death GO:0060548 345 0.087
Human Mouse
purine ribonucleoside catabolic process GO:0046130 398 0.084
regulation of cellular component biogenesis GO:0044087 281 0.084
regulation of kinase activity GO:0043549 314 0.083
Human
organ morphogenesis GO:0009887 147 0.082
actin filament based process GO:0030029 224 0.081
glycosyl compound catabolic process GO:1901658 413 0.081
cellular component morphogenesis GO:0032989 314 0.080
response to abiotic stimulus GO:0009628 336 0.078
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.078
Human
ribonucleoside catabolic process GO:0042454 406 0.076
generation of neurons GO:0048699 152 0.076
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.076
negative regulation of developmental process GO:0051093 247 0.074
Rat
cellular response to growth factor stimulus GO:0071363 197 0.072
nucleotide catabolic process GO:0009166 408 0.072
positive regulation of cell motility GO:2000147 177 0.072
regulation of nucleotide metabolic process GO:0006140 269 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
cell morphogenesis GO:0000902 296 0.071
cell projection organization GO:0030030 252 0.071
Rat
negative regulation of protein metabolic process GO:0051248 391 0.070
Human
regulation of cellular component movement GO:0051270 334 0.070
nucleoside triphosphate metabolic process GO:0009141 422 0.070
positive regulation of hydrolase activity GO:0051345 331 0.070
small gtpase mediated signal transduction GO:0007264 78 0.068
Rat
mitotic cell cycle GO:0000278 326 0.068
positive regulation of cellular amine metabolic process GO:0033240 7 0.068
positive regulation of phosphorylation GO:0042327 394 0.068
Human
vasculature development GO:0001944 181 0.068
regulation of transferase activity GO:0051338 355 0.068
Human
positive regulation of cell proliferation GO:0008284 301 0.068
negative regulation of programmed cell death GO:0043069 321 0.067
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.066
negative regulation of apoptotic process GO:0043066 316 0.066
Human Mouse
epithelial cell proliferation GO:0050673 128 0.066
neurogenesis GO:0022008 169 0.066
Rat
regulation of cell motility GO:2000145 299 0.066
nucleoside phosphate catabolic process GO:1901292 412 0.065
purine nucleotide catabolic process GO:0006195 405 0.065
tissue morphogenesis GO:0048729 96 0.065
regulation of cell migration GO:0030334 289 0.064
negative regulation of phosphate metabolic process GO:0045936 267 0.064
Human
locomotory behavior GO:0007626 1 0.063
nucleoside triphosphate catabolic process GO:0009143 394 0.062
enzyme linked receptor protein signaling pathway GO:0007167 303 0.062
positive regulation of developmental process GO:0051094 314 0.062
ribonucleoside triphosphate catabolic process GO:0009203 391 0.062
epidermis morphogenesis GO:0048730 3 0.062
purine nucleoside triphosphate catabolic process GO:0009146 392 0.061
single organism membrane organization GO:0044802 268 0.061
anatomical structure formation involved in morphogenesis GO:0048646 284 0.059
regulation of anatomical structure morphogenesis GO:0022603 286 0.059
purine ribonucleotide catabolic process GO:0009154 404 0.059
purine containing compound catabolic process GO:0072523 411 0.058
positive regulation of locomotion GO:0040017 186 0.057
positive regulation of cellular component organization GO:0051130 376 0.056
Human Yeast
regulation of epithelial cell proliferation GO:0050678 113 0.056
system process GO:0003008 349 0.056
Mouse
blood vessel morphogenesis GO:0048514 162 0.056
positive regulation of cell death GO:0010942 263 0.055
regulation of cell development GO:0060284 161 0.055
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.054
organophosphate catabolic process GO:0046434 430 0.054
cardiovascular system development GO:0072358 262 0.053
hindbrain development GO:0030902 3 0.052
oogenesis GO:0048477 2 0.051
regulation of cell cycle GO:0051726 393 0.051
female gamete generation GO:0007292 2 0.051
ameboidal type cell migration GO:0001667 135 0.050
multicellular organismal aging GO:0010259 3 0.050
heart morphogenesis GO:0003007 48 0.050
response to lipid GO:0033993 206 0.050
response to organic cyclic compound GO:0014070 204 0.049
positive regulation of cell migration GO:0030335 172 0.049
positive regulation of apoptotic process GO:0043065 246 0.049
single organism cellular localization GO:1902580 332 0.048
cellular macromolecular complex assembly GO:0034622 324 0.048
negative regulation of cell adhesion GO:0007162 64 0.047
blood vessel development GO:0001568 172 0.047
neuron development GO:0048666 113 0.047
Rat
actin cytoskeleton organization GO:0030036 207 0.047
negative regulation of protein modification process GO:0031400 200 0.047
Human
adult locomotory behavior GO:0008344 1 0.047
gtp catabolic process GO:0006184 237 0.047
angiogenesis GO:0001525 147 0.047
single organismal cell cell adhesion GO:0016337 148 0.046
guanosine containing compound catabolic process GO:1901069 239 0.046
rho protein signal transduction GO:0007266 26 0.045
positive regulation of transport GO:0051050 336 0.044
Human
negative regulation of cellular amine metabolic process GO:0033239 3 0.044
single organism cell adhesion GO:0098602 179 0.043
epithelium migration GO:0090132 119 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.042
Human
membrane organization GO:0061024 292 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
lipid metabolic process GO:0006629 381 0.042
regulation of nucleotide catabolic process GO:0030811 205 0.041
immune response GO:0006955 307 0.041
regulation of purine nucleotide metabolic process GO:1900542 264 0.041
mating GO:0007618 1 0.041
cell morphogenesis involved in differentiation GO:0000904 144 0.041
cation transport GO:0006812 331 0.041
mapk cascade GO:0000165 288 0.040
positive regulation of cellular catabolic process GO:0031331 284 0.040
Human Rat
cell junction organization GO:0034330 79 0.040
dephosphorylation GO:0016311 209 0.040
taxis GO:0042330 157 0.040
regulation of mapk cascade GO:0043408 262 0.040
regulation of protein kinase activity GO:0045859 289 0.040
Human
segmentation GO:0035282 4 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
regulation of purine nucleotide catabolic process GO:0033121 205 0.039
cellular lipid metabolic process GO:0044255 303 0.039
negative regulation of hydrolase activity GO:0051346 182 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.039
Human
vesicle mediated transport GO:0016192 371 0.039
positive regulation of programmed cell death GO:0043068 249 0.039
endothelial cell migration GO:0043542 86 0.039
cytoplasmic transport GO:0016482 379 0.038
regulation of gtp catabolic process GO:0033124 180 0.038
determination of adult lifespan GO:0008340 2 0.038
regulation of protein transport GO:0051223 213 0.038
Human
cell fate determination GO:0001709 3 0.038
positive regulation of nucleotide metabolic process GO:0045981 230 0.038
positive regulation of cellular component movement GO:0051272 181 0.038
regeneration GO:0031099 4 0.037
regulation of gtpase activity GO:0043087 180 0.037
tube development GO:0035295 125 0.037
apoptotic signaling pathway GO:0097190 268 0.036
regulation of response to external stimulus GO:0032101 222 0.036
regulation of protein complex assembly GO:0043254 147 0.036
regulation of nucleoside metabolic process GO:0009118 209 0.036
salivary gland morphogenesis GO:0007435 4 0.036
epithelial cell migration GO:0010631 119 0.036
positive regulation of cell differentiation GO:0045597 211 0.035
defense response GO:0006952 315 0.035
regulation of protein localization GO:0032880 296 0.035
Human
regulation of cytoskeleton organization GO:0051493 177 0.035
divalent metal ion transport GO:0070838 152 0.035
cell cell signaling GO:0007267 155 0.035
Mouse Rat
hemopoiesis GO:0030097 180 0.035
cell activation GO:0001775 213 0.034
nerve development GO:0021675 4 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.034
metal ion transport GO:0030001 272 0.034
transmembrane transport GO:0055085 399 0.034
cellular response to endogenous stimulus GO:0071495 336 0.033
protein catabolic process GO:0030163 325 0.033
Human Rat
inner ear morphogenesis GO:0042472 4 0.033
cation homeostasis GO:0055080 189 0.032
secretion GO:0046903 254 0.032
positive regulation of transferase activity GO:0051347 227 0.032
Human
wnt signaling pathway GO:0016055 156 0.032
response to oxygen containing compound GO:1901700 369 0.031
Human
negative regulation of cell migration GO:0030336 102 0.031
protein maturation GO:0051604 233 0.031
Human
behavior GO:0007610 112 0.031
Mouse
neuron projection development GO:0031175 106 0.031
Rat
positive regulation of proteolysis GO:0045862 142 0.031
Human Rat
neuromuscular junction development GO:0007528 3 0.031
neurological system process GO:0050877 163 0.031
Mouse
regulation of proteolysis GO:0030162 293 0.031
Human Rat
calcium ion transport GO:0006816 147 0.031
reactive oxygen species metabolic process GO:0072593 75 0.031
regulation of cell cycle process GO:0010564 266 0.030
spinal cord development GO:0021510 4 0.030
neural crest cell development GO:0014032 3 0.030
divalent inorganic cation transport GO:0072511 158 0.030
regulation of cell morphogenesis GO:0022604 153 0.030
gtp metabolic process GO:0046039 239 0.030
regulation of cellular response to stress GO:0080135 244 0.029
neuron differentiation GO:0030182 138 0.029
Rat
positive regulation of synaptic transmission GO:0050806 4 0.029
Rat
wound healing GO:0042060 115 0.029
cardiac right ventricle morphogenesis GO:0003215 3 0.029
leukocyte activation GO:0045321 164 0.029
immune system development GO:0002520 195 0.029
regulation of cellular response to growth factor stimulus GO:0090287 76 0.029
regulation of intracellular transport GO:0032386 195 0.029
Human
ion transmembrane transport GO:0034220 338 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
Human Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.028
morphogenesis of an epithelium GO:0002009 60 0.028
positive regulation of nucleoside metabolic process GO:0045979 186 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
Human
secretion by cell GO:0032940 226 0.028
negative regulation of cellular component organization GO:0051129 235 0.028
Human Rat
response to biotic stimulus GO:0009607 276 0.028
intracellular protein transport GO:0006886 270 0.027
Human
embryonic epithelial tube formation GO:0001838 4 0.027
cell substrate adhesion GO:0031589 132 0.027
cellular response to external stimulus GO:0071496 111 0.027
chemotaxis GO:0006935 157 0.027
regulation of cytokine production GO:0001817 232 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
Human
response to cytokine GO:0034097 232 0.026
regulation of establishment of protein localization GO:0070201 242 0.026
Human
cell projection morphogenesis GO:0048858 129 0.026
protein processing GO:0016485 226 0.026
Human
ion homeostasis GO:0050801 230 0.026
brain development GO:0007420 97 0.026
regulation of ras gtpase activity GO:0032318 128 0.026
guanosine containing compound metabolic process GO:1901068 244 0.026
cell growth GO:0016049 160 0.026
rhythmic behavior GO:0007622 2 0.026
negative regulation of locomotion GO:0040013 118 0.026
positive regulation of protein kinase activity GO:0045860 190 0.026
cell cell junction organization GO:0045216 69 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
positive regulation of ras gtpase activity GO:0032320 117 0.026
regulation of synaptic plasticity GO:0048167 3 0.026
Mouse Rat
motor neuron axon guidance GO:0008045 2 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
cellular protein complex assembly GO:0043623 188 0.026
hematopoietic or lymphoid organ development GO:0048534 186 0.026
protein localization to organelle GO:0033365 280 0.026
Human
myeloid cell differentiation GO:0030099 117 0.025
neuron fate commitment GO:0048663 2 0.025
cytokine production GO:0001816 247 0.025
positive regulation of nucleotide catabolic process GO:0030813 185 0.025
response to other organism GO:0051707 261 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
Human
mitotic cell cycle process GO:1903047 286 0.024
regulation of peptidase activity GO:0052547 180 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
Human
positive regulation of gtp catabolic process GO:0033126 166 0.024
protein ubiquitination GO:0016567 314 0.024
Human
oocyte differentiation GO:0009994 2 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
regulation of canonical wnt signaling pathway GO:0060828 88 0.024
peripheral nervous system development GO:0007422 2 0.024
neurotransmitter secretion GO:0007269 4 0.024
positive regulation of immune system process GO:0002684 283 0.024
positive regulation of catabolic process GO:0009896 310 0.024
Human Rat
cellular protein catabolic process GO:0044257 261 0.024
Human Rat
cell part morphogenesis GO:0032990 137 0.024
regulation of growth GO:0040008 165 0.024
response to radiation GO:0009314 151 0.024
Human
chemical homeostasis GO:0048878 306 0.024
cellular response to organic cyclic compound GO:0071407 127 0.023
epithelial cell differentiation GO:0030855 141 0.023
central nervous system development GO:0007417 123 0.023
reactive oxygen species biosynthetic process GO:1903409 4 0.023
negative regulation of cell cycle GO:0045786 193 0.023
Human Mouse
neural tube formation GO:0001841 3 0.023
microtubule based process GO:0007017 210 0.023
canonical wnt signaling pathway GO:0060070 116 0.023
tissue migration GO:0090130 119 0.023
sex determination GO:0007530 3 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
digestive tract development GO:0048565 75 0.023
regulation of reactive oxygen species metabolic process GO:2000377 41 0.023
ossification GO:0001503 121 0.022
pituitary gland development GO:0021983 2 0.022
oocyte development GO:0048599 1 0.022
regulation of cell growth GO:0001558 135 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
negative regulation of response to external stimulus GO:0032102 83 0.022
immune effector process GO:0002252 159 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
morphogenesis of embryonic epithelium GO:0016331 4 0.022
neuroblast proliferation GO:0007405 4 0.022
negative regulation of transport GO:0051051 176 0.022
proteasomal protein catabolic process GO:0010498 176 0.022
Human Rat
regulation of wnt signaling pathway GO:0030111 123 0.022
growth GO:0040007 202 0.022
head development GO:0060322 108 0.022
positive regulation of mapk cascade GO:0043410 190 0.022
negative regulation of kinase activity GO:0033673 106 0.022
Human
carbohydrate metabolic process GO:0005975 207 0.022
regulation of ion transport GO:0043269 189 0.022
cellular response to lipid GO:0071396 127 0.022
erk1 and erk2 cascade GO:0070371 104 0.022
lymphocyte activation GO:0046649 133 0.022
embryo development GO:0009790 123 0.021
muscle structure development GO:0061061 98 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
Human Rat
regulation of cell substrate adhesion GO:0010810 68 0.021
response to nitrogen compound GO:1901698 184 0.021
anterior posterior axis specification GO:0009948 2 0.021
response to wounding GO:0009611 168 0.021
actin filament organization GO:0007015 128 0.021
tube morphogenesis GO:0035239 95 0.021
regulation of secretion GO:0051046 194 0.021
endodermal cell fate specification GO:0001714 4 0.021
memory GO:0007613 3 0.021
Mouse
regulation of neural precursor cell proliferation GO:2000177 4 0.021
digestive system development GO:0055123 75 0.021
chromatin modification GO:0016568 298 0.021
lipid biosynthetic process GO:0008610 177 0.021
regulation of vasculature development GO:1901342 97 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
Human
cellular chemical homeostasis GO:0055082 180 0.021
regulation of ossification GO:0030278 58 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
negative regulation of gliogenesis GO:0014014 3 0.020
heart development GO:0007507 95 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
maintenance of location GO:0051235 112 0.020
regulation of protein processing GO:0070613 150 0.020
Human
compound eye development GO:0048749 1 0.020
regulation of neurotransmitter secretion GO:0046928 3 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
Human
stem cell division GO:0017145 2 0.020
peptidyl tyrosine phosphorylation GO:0018108 170 0.020
organ formation GO:0048645 3 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
small molecule biosynthetic process GO:0044283 157 0.020
chromatin organization GO:0006325 351 0.020
regulation of neuron differentiation GO:0045664 70 0.020
Rat
positive regulation of protein complex assembly GO:0031334 86 0.020
negative regulation of immune system process GO:0002683 136 0.020
protein localization to membrane GO:0072657 160 0.020
endomembrane system organization GO:0010256 196 0.020
Human
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
associative learning GO:0008306 1 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
Rat
regulation of secretion by cell GO:1903530 177 0.019
endodermal cell fate commitment GO:0001711 4 0.019
limbic system development GO:0021761 3 0.019
protein dephosphorylation GO:0006470 81 0.019
regulation of neurogenesis GO:0050767 82 0.019
Rat
kidney development GO:0001822 53 0.019
negative regulation of protein maturation GO:1903318 142 0.019
Human
regulation of endopeptidase activity GO:0052548 170 0.019
regulation of nervous system development GO:0051960 88 0.019
Rat
skeletal system development GO:0001501 79 0.019
t cell differentiation in thymus GO:0033077 4 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
negative regulation of transferase activity GO:0051348 124 0.019
Human
response to axon injury GO:0048678 1 0.019
blastoderm segmentation GO:0007350 2 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
regulation of actin filament based process GO:0032970 141 0.019
purine nucleoside monophosphate catabolic process GO:0009128 158 0.019
regulation of epithelial cell migration GO:0010632 93 0.019
response to organonitrogen compound GO:0010243 156 0.019
osteoblast differentiation GO:0001649 92 0.019
regulation of homeostatic process GO:0032844 121 0.019
atp metabolic process GO:0046034 176 0.019
regulation of ras protein signal transduction GO:0046578 155 0.018
cellular response to glucocorticoid stimulus GO:0071385 4 0.018
skin development GO:0043588 76 0.018
calcium ion homeostasis GO:0055074 122 0.018
cell cycle phase transition GO:0044770 173 0.018
forebrain generation of neurons GO:0021872 3 0.018
positive regulation of organelle organization GO:0010638 195 0.018
Human Yeast
primary neural tube formation GO:0014020 3 0.018
regulation of stress activated mapk cascade GO:0032872 84 0.018
cellular homeostasis GO:0019725 196 0.018
divalent inorganic cation homeostasis GO:0072507 136 0.018
positive regulation of kinase activity GO:0033674 204 0.018
nitrogen compound transport GO:0071705 191 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
cell division GO:0051301 168 0.018
Human
regulation of rho gtpase activity GO:0032319 66 0.018
cranial nerve development GO:0021545 4 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
positive regulation of cytokine production GO:0001819 167 0.018
somatic stem cell maintenance GO:0035019 4 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
negative regulation of epithelial cell proliferation GO:0050680 48 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
Human
cellular response to cytokine stimulus GO:0071345 181 0.017
response to hormone GO:0009725 175 0.017
regulation of map kinase activity GO:0043405 108 0.017
regulation of angiogenesis GO:0045765 92 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
regulation of response to wounding GO:1903034 101 0.017
cellular cation homeostasis GO:0030003 163 0.017
cerebral cortex cell migration GO:0021795 3 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
hair follicle morphogenesis GO:0031069 2 0.017
blood circulation GO:0008015 113 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
atp catabolic process GO:0006200 157 0.017
nucleotide biosynthetic process GO:0009165 109 0.017
nucleoside monophosphate catabolic process GO:0009125 159 0.017
regulation of calcium ion transport GO:0051924 79 0.017
cell junction assembly GO:0034329 67 0.017
innate immune response GO:0045087 178 0.017
regulation of metal ion transport GO:0010959 120 0.017
tripartite regional subdivision GO:0007351 2 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
Human
protein targeting GO:0006605 187 0.017
leukocyte differentiation GO:0002521 98 0.017
neuron projection regeneration GO:0031102 1 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
sequestering of calcium ion GO:0051208 17 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.016
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
Human Rat
somatic stem cell division GO:0048103 1 0.016
positive regulation of epithelial cell proliferation GO:0050679 65 0.016
embryonic placenta development GO:0001892 1 0.016
cellular ion homeostasis GO:0006873 168 0.016
rna interference GO:0016246 4 0.016
follicle stimulating hormone secretion GO:0046884 3 0.016
metal ion homeostasis GO:0055065 169 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
endocytosis GO:0006897 159 0.016
spermatid differentiation GO:0048515 4 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
single organism reproductive process GO:0044702 98 0.016
response to transforming growth factor beta GO:0071559 94 0.016
lung alveolus development GO:0048286 4 0.016
endocardial cushion development GO:0003197 3 0.016
regulation of multi organism process GO:0043900 157 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
Human Rat
spermatid development GO:0007286 4 0.016
positive regulation of cell development GO:0010720 92 0.016
cellular response to abiotic stimulus GO:0071214 117 0.016
negative regulation of proteolysis GO:0045861 132 0.016
Human
nuclear transport GO:0051169 179 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
negative regulation of organelle organization GO:0010639 126 0.016
Human
regulation of cell activation GO:0050865 125 0.015
regulation of endothelial cell migration GO:0010594 67 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
regulation of leukocyte activation GO:0002694 115 0.015
translation GO:0006412 132 0.015
circadian behavior GO:0048512 2 0.015
negative regulation of cytokine production GO:0001818 82 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
negative regulation of wnt signaling pathway GO:0030178 69 0.015
response to nutrient levels GO:0031667 81 0.015
metencephalon development GO:0022037 2 0.015
rna processing GO:0006396 255 0.015
ventral spinal cord development GO:0021517 1 0.015
neural tube closure GO:0001843 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
Human Rat
covalent chromatin modification GO:0016569 254 0.015
muscle organ development GO:0007517 56 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
t cell activation GO:0042110 99 0.015
negative regulation of protein processing GO:0010955 142 0.015
Human
thymus development GO:0048538 3 0.015
glycoprotein metabolic process GO:0009100 110 0.015
negative regulation of growth GO:0045926 97 0.015

PLK2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.029
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
disease of metabolism DOID:0014667 295 0.021
sensory system disease DOID:0050155 203 0.021
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.019
organ system cancer DOID:0050686 164 0.018
cardiovascular system disease DOID:1287 106 0.018