Homo sapiens

0 known processes

NSFL1C

NSFL1 (p97) cofactor (p47)

(Aliases: dJ776F14.1,UBXD10,UBX1,UBXN2C,P47,MGC3347,FLJ46889)

NSFL1C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to misfolded protein GO:0071218 2 0.977
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.577
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.315
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.302
Yeast
modification dependent protein catabolic process GO:0019941 209 0.266
Yeast
response to misfolded protein GO:0051788 5 0.263
protein catabolic process GO:0030163 325 0.255
Yeast
cellular response to topologically incorrect protein GO:0035967 19 0.232
modification dependent macromolecule catabolic process GO:0043632 212 0.202
Yeast
ubiquitin dependent protein catabolic process GO:0006511 206 0.201
Yeast
er associated misfolded protein catabolic process GO:0071712 1 0.199
cellular macromolecule catabolic process GO:0044265 380 0.192
Yeast
microtubule cytoskeleton organization GO:0000226 176 0.158
Yeast
intracellular protein transport GO:0006886 270 0.138
proteasomal protein catabolic process GO:0010498 176 0.137
Yeast
regulation of protein deubiquitination GO:0090085 4 0.136
cellular protein catabolic process GO:0044257 261 0.136
Yeast
response to topologically incorrect protein GO:0035966 29 0.127
cytoplasmic transport GO:0016482 379 0.121
single organism membrane organization GO:0044802 268 0.116
Yeast Fly
mitotic cell cycle process GO:1903047 286 0.113
Yeast
regulation of protein localization GO:0032880 296 0.108
nuclear envelope reassembly GO:0031468 3 0.106
Fly
protein modification by small protein conjugation GO:0032446 342 0.098
protein localization to nucleus GO:0034504 136 0.091
protein maturation GO:0051604 233 0.087
cell development GO:0048468 328 0.086
Yeast Fly
protein k63 linked deubiquitination GO:0070536 21 0.080
cellular response to dna damage stimulus GO:0006974 379 0.079
macromolecule glycosylation GO:0043413 63 0.077
rna catabolic process GO:0006401 71 0.073
retrograde protein transport er to cytosol GO:0030970 5 0.070
cell cell signaling GO:0007267 155 0.068
maintenance of location GO:0051235 112 0.066
Yeast
locomotory behavior GO:0007626 1 0.063
mitotic cell cycle GO:0000278 326 0.061
Yeast
single organism cellular localization GO:1902580 332 0.059
multicellular organismal aging GO:0010259 3 0.058
trabecula morphogenesis GO:0061383 2 0.055
protein glycosylation GO:0006486 62 0.053
carbohydrate derivative biosynthetic process GO:1901137 207 0.053
regulation of synaptic plasticity GO:0048167 3 0.052
oogenesis GO:0048477 2 0.051
circulatory system development GO:0072359 262 0.050
cellular macromolecular complex assembly GO:0034622 324 0.049
cellular response to oxygen containing compound GO:1901701 276 0.048
single organism reproductive process GO:0044702 98 0.047
Yeast
defense response GO:0006952 315 0.046
enzyme linked receptor protein signaling pathway GO:0007167 303 0.044
nervous system development GO:0007399 293 0.044
Fly
positive regulation of synaptic transmission GO:0050806 4 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
regulation of proteolysis GO:0030162 293 0.043
chromatin organization GO:0006325 351 0.043
associative learning GO:0008306 1 0.042
protein processing GO:0016485 226 0.042
cardiac ventricle morphogenesis GO:0003208 20 0.041
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
protein n linked glycosylation via asparagine GO:0018279 10 0.040
cardiac chamber morphogenesis GO:0003206 26 0.039
post embryonic development GO:0009791 2 0.039
glycoprotein biosynthetic process GO:0009101 91 0.038
vesicle mediated transport GO:0016192 371 0.038
negative regulation of multicellular organismal process GO:0051241 317 0.038
positive regulation of cell death GO:0010942 263 0.037
regulation of protein localization to nucleus GO:1900180 85 0.036
neurological system process GO:0050877 163 0.036
response to endoplasmic reticulum stress GO:0034976 49 0.036
determination of adult lifespan GO:0008340 2 0.035
ncrna metabolic process GO:0034660 108 0.035
protein ubiquitination GO:0016567 314 0.035
ncrna catabolic process GO:0034661 14 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
histone modification GO:0016570 251 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.034
cellular ketone metabolic process GO:0042180 80 0.034
macromolecular complex disassembly GO:0032984 60 0.034
microtubule based process GO:0007017 210 0.034
Yeast
regulation of protein maturation GO:1903317 150 0.034
biological adhesion GO:0022610 331 0.034
regulation of protein ubiquitination GO:0031396 95 0.034
organ morphogenesis GO:0009887 147 0.033
Fly
organelle fission GO:0048285 149 0.032
Yeast
chromosome segregation GO:0007059 114 0.032
Yeast
membrane organization GO:0061024 292 0.032
Yeast Rat Fly
synaptic transmission GO:0007268 61 0.031
dephosphorylation GO:0016311 209 0.031
Yeast
response to abiotic stimulus GO:0009628 336 0.031
double strand break repair GO:0006302 101 0.030
regulation of metal ion transport GO:0010959 120 0.030
amine metabolic process GO:0009308 44 0.030
cation transmembrane transport GO:0098655 238 0.029
regulation of ion transmembrane transport GO:0034765 132 0.029
positive regulation of cellular component organization GO:0051130 376 0.028
activation of cysteine type endopeptidase activity GO:0097202 57 0.028
organelle membrane fusion GO:0090174 5 0.028
chromatin modification GO:0016568 298 0.027
positive regulation of protein localization to nucleus GO:1900182 48 0.027
oocyte differentiation GO:0009994 2 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
protein localization to membrane GO:0072657 160 0.026
nucleus localization GO:0051647 1 0.026
regulation of cysteine type endopeptidase activity GO:2000116 127 0.026
transmembrane transport GO:0055085 399 0.026
cell adhesion GO:0007155 325 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
segmentation GO:0035282 4 0.026
response to unfolded protein GO:0006986 24 0.026
er nucleus signaling pathway GO:0006984 23 0.025
glycerolipid metabolic process GO:0046486 107 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
carbohydrate metabolic process GO:0005975 207 0.025
Yeast
cellular protein complex assembly GO:0043623 188 0.025
protein autoubiquitination GO:0051865 37 0.024
reproductive process GO:0022414 106 0.024
Yeast
response to oxygen containing compound GO:1901700 369 0.023
protein localization to organelle GO:0033365 280 0.023
regulation of protein catabolic process GO:0042176 155 0.023
chemical homeostasis GO:0048878 306 0.023
glycerophospholipid metabolic process GO:0006650 84 0.023
blastoderm segmentation GO:0007350 2 0.023
monovalent inorganic cation transport GO:0015672 128 0.023
dna repair GO:0006281 198 0.023
endoplasmic reticulum unfolded protein response GO:0030968 16 0.023
regulation of chromosome organization GO:0033044 103 0.023
oocyte development GO:0048599 1 0.023
adult locomotory behavior GO:0008344 1 0.023
cellular amine metabolic process GO:0044106 41 0.022
regulation of intracellular transport GO:0032386 195 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
regulation of protein processing GO:0070613 150 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
neuromuscular junction development GO:0007528 3 0.021
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.021
Yeast
glycosylation GO:0070085 71 0.021
nuclear division GO:0000280 128 0.021
Yeast
regulation of endopeptidase activity GO:0052548 170 0.021
tissue morphogenesis GO:0048729 96 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
establishment of nucleus localization GO:0040023 1 0.021
female gamete generation GO:0007292 2 0.021
mitotic nuclear division GO:0007067 119 0.021
Yeast
organelle assembly GO:0070925 176 0.020
Yeast
negative regulation of catalytic activity GO:0043086 335 0.020
regulation of cell differentiation GO:0045595 393 0.020
apoptotic signaling pathway GO:0097190 268 0.020
cell projection organization GO:0030030 252 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
reproduction GO:0000003 63 0.020
Yeast
isocitrate metabolic process GO:0006102 1 0.020
positive regulation of endopeptidase activity GO:0010950 84 0.020
cellular component disassembly GO:0022411 92 0.020
cell cycle checkpoint GO:0000075 117 0.020
protein targeting GO:0006605 187 0.020
regulation of peptidase activity GO:0052547 180 0.020
organelle localization GO:0051640 84 0.020
Yeast
exploration behavior GO:0035640 1 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
jnk cascade GO:0007254 80 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
negative regulation of protein maturation GO:1903318 142 0.019
small gtpase mediated signal transduction GO:0007264 78 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
Yeast
secretion by cell GO:0032940 226 0.019
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
regulation of protein transport GO:0051223 213 0.019
generation of neurons GO:0048699 152 0.018
Fly
tripartite regional subdivision GO:0007351 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
cell morphogenesis GO:0000902 296 0.018
cellular response to nutrient levels GO:0031669 69 0.018
Yeast
reproductive system development GO:0061458 56 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
heart trabecula morphogenesis GO:0061384 1 0.018
neutral lipid metabolic process GO:0006638 27 0.018
regulation of protein complex assembly GO:0043254 147 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
membrane fusion GO:0061025 43 0.018
Rat
regulation of ion transport GO:0043269 189 0.018
regulation of chromatin organization GO:1902275 56 0.017
neuron differentiation GO:0030182 138 0.017
Fly
single organism membrane fusion GO:0044801 37 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
negative regulation of developmental process GO:0051093 247 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
stress activated protein kinase signaling cascade GO:0031098 94 0.017
ribonucleoprotein complex subunit organization GO:0071826 81 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
response to external biotic stimulus GO:0043207 261 0.017
regulation of cell adhesion GO:0030155 166 0.016
lipid metabolic process GO:0006629 381 0.016
endosomal transport GO:0016197 129 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.016
actin filament based process GO:0030029 224 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
long term synaptic potentiation GO:0060291 1 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
embryo development GO:0009790 123 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
zymogen activation GO:0031638 70 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
golgi vesicle transport GO:0048193 80 0.016
cardiovascular system development GO:0072358 262 0.016
regeneration GO:0031099 4 0.016
spermatid differentiation GO:0048515 4 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
aging GO:0007568 66 0.016
mitotic sister chromatid segregation GO:0000070 53 0.015
Yeast
inorganic cation transmembrane transport GO:0098662 194 0.015
positive regulation of developmental process GO:0051094 314 0.015
protein n linked glycosylation GO:0006487 23 0.015
regulation of protein import into nucleus GO:0042306 78 0.015
protein oligomerization GO:0051259 173 0.015
cellular component morphogenesis GO:0032989 314 0.015
glycoprotein metabolic process GO:0009100 110 0.015
negative regulation of smoothened signaling pathway GO:0045879 3 0.015
regulation of translation GO:0006417 89 0.015
multi organism reproductive process GO:0044703 54 0.015
Yeast
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
regulation of homeostatic process GO:0032844 121 0.015
cellular response to alcohol GO:0097306 29 0.015
cellular response to xenobiotic stimulus GO:0071466 29 0.015
positive regulation of organelle organization GO:0010638 195 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
behavior GO:0007610 112 0.014
intracellular mrna localization GO:0008298 1 0.014
maintenance of protein location GO:0045185 57 0.014
Yeast
anterior posterior axis specification GO:0009948 2 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
positive regulation of proteolysis GO:0045862 142 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
autophagy GO:0006914 88 0.014
Yeast
ras protein signal transduction GO:0007265 73 0.014
atp catabolic process GO:0006200 157 0.014
negative regulation of proteolysis GO:0045861 132 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
tricarboxylic acid metabolic process GO:0072350 4 0.014
nucleotide catabolic process GO:0009166 408 0.014
immune system development GO:0002520 195 0.014
regulation of neural precursor cell proliferation GO:2000177 4 0.014
heart development GO:0007507 95 0.014
developmental process involved in reproduction GO:0003006 66 0.013
Yeast
positive regulation of transport GO:0051050 336 0.013
sodium ion transport GO:0006814 61 0.013
alcohol metabolic process GO:0006066 114 0.013
ion homeostasis GO:0050801 230 0.013
mitochondrial transport GO:0006839 60 0.013
cellular lipid metabolic process GO:0044255 303 0.013
monosaccharide transport GO:0015749 32 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.013
atp metabolic process GO:0046034 176 0.013
reproductive structure development GO:0048608 55 0.013
phospholipid metabolic process GO:0006644 99 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
Fly
stress activated mapk cascade GO:0051403 93 0.013
positive regulation of apoptotic signaling pathway GO:2001235 70 0.013
response to biotic stimulus GO:0009607 276 0.013
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.013
response to hormone GO:0009725 175 0.013
coenzyme metabolic process GO:0006732 65 0.013
response to uv GO:0009411 73 0.013
er to golgi vesicle mediated transport GO:0006888 19 0.013
regulation of transporter activity GO:0032409 82 0.013
regulation of immune response GO:0050776 201 0.013
cell activation GO:0001775 213 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
multi organism cellular process GO:0044764 156 0.012
lipid localization GO:0010876 106 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.012
negative regulation of transport GO:0051051 176 0.012
cell part morphogenesis GO:0032990 137 0.012
dicarboxylic acid metabolic process GO:0043648 29 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.012
response to xenobiotic stimulus GO:0009410 30 0.012
protein homooligomerization GO:0051260 100 0.012
response to radiation GO:0009314 151 0.012
protein import GO:0017038 130 0.012
nitrogen compound transport GO:0071705 191 0.012
calcium ion transport GO:0006816 147 0.012
stem cell division GO:0017145 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
circadian sleep wake cycle process GO:0022410 2 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.012
nuclear import GO:0051170 106 0.012
nuclear migration GO:0007097 1 0.012
negative regulation of cell death GO:0060548 345 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
divalent metal ion transport GO:0070838 152 0.011
cofactor metabolic process GO:0051186 87 0.011
metal ion transport GO:0030001 272 0.011
cell projection morphogenesis GO:0048858 129 0.011
positive regulation of ion transport GO:0043270 87 0.011
establishment of protein localization to mitochondrion GO:0072655 22 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
regulation of jnk cascade GO:0046328 73 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
negative regulation of protein processing GO:0010955 142 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
ventricular trabecula myocardium morphogenesis GO:0003222 1 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
attachment of spindle microtubules to kinetochore GO:0008608 17 0.011
Yeast
urogenital system development GO:0001655 65 0.011
behavioral defense response GO:0002209 0 0.011
response to hypoxia GO:0001666 96 0.011
translation GO:0006412 132 0.011
growth GO:0040007 202 0.011
head development GO:0060322 108 0.011
ion transmembrane transport GO:0034220 338 0.011
spindle organization GO:0007051 53 0.011
neuron development GO:0048666 113 0.011
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.011
regulation of transferase activity GO:0051338 355 0.011
maintenance of location in cell GO:0051651 62 0.011
Yeast
positive regulation of anoikis GO:2000210 4 0.011
regulation of calcium ion transport GO:0051924 79 0.011
sodium ion transmembrane transport GO:0035725 59 0.011
system process GO:0003008 349 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
muscle tissue morphogenesis GO:0060415 19 0.011
response to alcohol GO:0097305 64 0.011
protein polyubiquitination GO:0000209 110 0.011
myoblast fusion GO:0007520 1 0.011
positive regulation of developmental growth GO:0048639 16 0.011
vesicle docking involved in exocytosis GO:0006904 3 0.011
rna splicing via transesterification reactions GO:0000375 90 0.011
detection of stimulus GO:0051606 85 0.011
rhythmic behavior GO:0007622 2 0.010
small molecule biosynthetic process GO:0044283 157 0.010
embryonic placenta development GO:0001892 1 0.010
organelle disassembly GO:1903008 9 0.010
cellular response to organic cyclic compound GO:0071407 127 0.010
lipid transport GO:0006869 90 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
neurotransmitter secretion GO:0007269 4 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
negative regulation of intracellular transport GO:0032387 60 0.010
thymus development GO:0048538 3 0.010
negative regulation of immune system process GO:0002683 136 0.010
cation transport GO:0006812 331 0.010
regulation of cell cycle GO:0051726 393 0.010
toxin transport GO:1901998 4 0.010
epithelium development GO:0060429 227 0.010
negative regulation of protein modification process GO:0031400 200 0.010

NSFL1C disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.097
eye and adnexa disease DOID:1492 150 0.097
nervous system disease DOID:863 431 0.097
eye disease DOID:5614 149 0.097
cancer DOID:162 167 0.084
disease of cellular proliferation DOID:14566 174 0.084
organ system cancer DOID:0050686 164 0.084
central nervous system disease DOID:331 186 0.066
neurodegenerative disease DOID:1289 102 0.040
retinal disease DOID:5679 118 0.038
retinal degeneration DOID:8466 89 0.025
retinitis pigmentosa DOID:10584 51 0.023
musculoskeletal system disease DOID:17 223 0.014
neuropathy DOID:870 52 0.013