Homo sapiens

0 known processes

APOL6

apolipoprotein L, 6

(Aliases: DKFZp667M075,APOL-VI,FLJ90164,FLJ38562,MGC57495,APOLVI)

APOL6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 276 0.428
response to other organism GO:0051707 261 0.335
defense response GO:0006952 315 0.329
multi organism cellular process GO:0044764 156 0.297
regulation of multi organism process GO:0043900 157 0.280
defense response to virus GO:0051607 71 0.279
defense response to other organism GO:0098542 129 0.266
immune response GO:0006955 307 0.262
response to external biotic stimulus GO:0043207 261 0.259
innate immune response GO:0045087 178 0.243
response to cytokine GO:0034097 232 0.240
interspecies interaction between organisms GO:0044419 156 0.213
response to virus GO:0009615 126 0.168
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.163
positive regulation of immune response GO:0050778 159 0.153
regulation of protein localization GO:0032880 296 0.146
glycosylation GO:0070085 71 0.145
macromolecule glycosylation GO:0043413 63 0.137
regulation of ribonuclease activity GO:0060700 3 0.130
regulation of defense response to virus GO:0050688 33 0.105
glycoprotein metabolic process GO:0009100 110 0.098
cytoplasmic transport GO:0016482 379 0.093
regulation of defense response GO:0031347 154 0.090
regulation of innate immune response GO:0045088 97 0.090
regulation of response to external stimulus GO:0032101 222 0.089
protein glycosylation GO:0006486 62 0.080
positive regulation of transport GO:0051050 336 0.080
response to nitrogen compound GO:1901698 184 0.080
organophosphate biosynthetic process GO:0090407 163 0.072
activation of immune response GO:0002253 114 0.067
positive regulation of cytokine production GO:0001819 167 0.065
carbohydrate derivative biosynthetic process GO:1901137 207 0.065
protein targeting GO:0006605 187 0.065
immune effector process GO:0002252 159 0.065
protein localization to organelle GO:0033365 280 0.063
intracellular protein transport GO:0006886 270 0.062
regulation of immune effector process GO:0002697 91 0.062
chloride transport GO:0006821 41 0.059
positive regulation of innate immune response GO:0045089 79 0.058
regulation of immune response GO:0050776 201 0.057
regulation of establishment of protein localization GO:0070201 242 0.057
regulation of protein localization to nucleus GO:1900180 85 0.057
glycoprotein biosynthetic process GO:0009101 91 0.056
regulation of response to biotic stimulus GO:0002831 55 0.054
response to interferon gamma GO:0034341 39 0.053
organonitrogen compound biosynthetic process GO:1901566 200 0.052
immune response activating signal transduction GO:0002757 90 0.052
defense response to bacterium GO:0042742 63 0.051
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.050
positive regulation of programmed cell death GO:0043068 249 0.049
cellular response to cytokine stimulus GO:0071345 181 0.049
carbohydrate metabolic process GO:0005975 207 0.048
protein import into nucleus GO:0006606 104 0.047
positive regulation of intracellular transport GO:0032388 104 0.046
chemical homeostasis GO:0048878 306 0.045
leukocyte activation GO:0045321 164 0.044
positive regulation of immune system process GO:0002684 283 0.044
positive regulation of interferon beta production GO:0032728 17 0.044
positive regulation of cell death GO:0010942 263 0.044
response to dsrna GO:0043331 25 0.043
regulation of cell cycle GO:0051726 393 0.043
transmembrane transport GO:0055085 399 0.043
nucleoside phosphate biosynthetic process GO:1901293 109 0.041
nucleotide biosynthetic process GO:0009165 109 0.041
positive regulation of rig i signaling pathway GO:1900246 4 0.040
lipoprotein metabolic process GO:0042157 42 0.040
ion transmembrane transport GO:0034220 338 0.040
i kappab kinase nf kappab signaling GO:0007249 166 0.039
protein oligomerization GO:0051259 173 0.039
cell fate determination GO:0001709 3 0.039
negative regulation of intracellular signal transduction GO:1902532 183 0.039
purine nucleotide biosynthetic process GO:0006164 84 0.038
regulation of cytokine production GO:0001817 232 0.038
single organism cellular localization GO:1902580 332 0.038
cellular response to dna damage stimulus GO:0006974 379 0.037
negative regulation of multicellular organismal process GO:0051241 317 0.037
vesicle mediated transport GO:0016192 371 0.037
cellular response to interferon alpha GO:0035457 4 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
viral life cycle GO:0019058 132 0.036
nuclear transport GO:0051169 179 0.035
regulation of protein import into nucleus GO:0042306 78 0.035
activation of innate immune response GO:0002218 55 0.034
positive regulation of hydrolase activity GO:0051345 331 0.034
response to abiotic stimulus GO:0009628 336 0.034
protein acylation GO:0043543 138 0.033
biological adhesion GO:0022610 331 0.033
regulation of cytoplasmic transport GO:1903649 149 0.033
cytokine production GO:0001816 247 0.032
protein modification by small protein conjugation GO:0032446 342 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.031
inorganic anion transmembrane transport GO:0098661 47 0.031
positive regulation of protein transport GO:0051222 135 0.031
establishment of protein localization to organelle GO:0072594 172 0.031
positive regulation of multi organism process GO:0043902 56 0.031
negative regulation of multi organism process GO:0043901 92 0.030
leukocyte differentiation GO:0002521 98 0.030
protein localization to nucleus GO:0034504 136 0.030
negative regulation of cell proliferation GO:0008285 228 0.030
negative regulation of defense response to virus GO:0050687 10 0.029
purine containing compound biosynthetic process GO:0072522 88 0.029
positive regulation of interferon alpha production GO:0032727 11 0.029
rna interference GO:0016246 4 0.029
immune response regulating signaling pathway GO:0002764 97 0.029
innate immune response activating signal transduction GO:0002758 48 0.029
monosaccharide metabolic process GO:0005996 74 0.029
positive regulation of type i interferon production GO:0032481 20 0.028
protein secretion GO:0009306 98 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.028
negative regulation of viral process GO:0048525 66 0.028
determination of adult lifespan GO:0008340 2 0.027
multicellular organismal aging GO:0010259 3 0.027
compound eye development GO:0048749 1 0.027
regulation of viral process GO:0050792 103 0.027
single organism carbohydrate metabolic process GO:0044723 193 0.027
oogenesis GO:0048477 2 0.027
pattern recognition receptor signaling pathway GO:0002221 48 0.027
positive regulation of apoptotic process GO:0043065 246 0.027
protein catabolic process GO:0030163 325 0.026
cellular response to external stimulus GO:0071496 111 0.026
cellular ketone metabolic process GO:0042180 80 0.026
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.026
organic hydroxy compound metabolic process GO:1901615 147 0.026
viral process GO:0016032 146 0.025
regulation of protein transport GO:0051223 213 0.025
regulation of dna metabolic process GO:0051052 153 0.025
negative regulation of cell cycle GO:0045786 193 0.025
anion transport GO:0006820 161 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of lymphocyte activation GO:0051249 103 0.025
cellular response to nitrogen compound GO:1901699 144 0.025
regulation of cellular component biogenesis GO:0044087 281 0.024
response to oxygen containing compound GO:1901700 369 0.024
nucleocytoplasmic transport GO:0006913 176 0.024
spermatid development GO:0007286 4 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
protein myristoylation GO:0018377 1 0.024
cell activation GO:0001775 213 0.024
protein ubiquitination GO:0016567 314 0.023
regulation of protein targeting GO:1903533 91 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
negative regulation of mitotic cell cycle GO:0045930 102 0.023
system process GO:0003008 349 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
single organism nuclear import GO:1902593 104 0.023
regulation of cell differentiation GO:0045595 393 0.023
intracellular receptor signaling pathway GO:0030522 104 0.023
protein targeting to nucleus GO:0044744 104 0.022
regulation of viral genome replication GO:0045069 48 0.022
positive regulation of cell differentiation GO:0045597 211 0.022
regulation of intracellular transport GO:0032386 195 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
sensory perception of taste GO:0050909 36 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
regulation of angiogenesis GO:0045765 92 0.022
negative regulation of intracellular transport GO:0032387 60 0.022
post embryonic development GO:0009791 2 0.022
spermatid differentiation GO:0048515 4 0.022
positive regulation of mapk cascade GO:0043410 190 0.021
regulation of defense response to virus by host GO:0050691 22 0.021
response to interferon beta GO:0035456 11 0.021
t cell activation GO:0042110 99 0.021
melanin metabolic process GO:0006582 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
cell cycle arrest GO:0007050 71 0.021
cellular amino acid metabolic process GO:0006520 116 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
apoptotic signaling pathway GO:0097190 268 0.020
negative regulation of vasculature development GO:1901343 43 0.020
female gamete generation GO:0007292 2 0.020
regulation of leukocyte activation GO:0002694 115 0.020
regulation of interferon beta production GO:0032648 22 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
positive regulation of catabolic process GO:0009896 310 0.020
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
regulation of secretion GO:0051046 194 0.020
anion transmembrane transport GO:0098656 76 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.019
secretion GO:0046903 254 0.019
regulation of nucleocytoplasmic transport GO:0046822 98 0.019
mitotic cell cycle GO:0000278 326 0.019
anatomical structure homeostasis GO:0060249 100 0.019
metal ion transport GO:0030001 272 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
response to radiation GO:0009314 151 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
cell cycle phase transition GO:0044770 173 0.019
membrane organization GO:0061024 292 0.018
viral genome replication GO:0019079 50 0.018
nuclear import GO:0051170 106 0.018
regulation of transferase activity GO:0051338 355 0.018
positive regulation of defense response GO:0031349 87 0.018
positive regulation of intracellular protein transport GO:0090316 76 0.018
lipoprotein biosynthetic process GO:0042158 33 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
nucleotide catabolic process GO:0009166 408 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.018
organophosphate catabolic process GO:0046434 430 0.018
myoblast fusion GO:0007520 1 0.018
interferon alpha production GO:0032607 11 0.018
hemopoiesis GO:0030097 180 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.018
mhc class ii biosynthetic process GO:0045342 4 0.017
protein polyubiquitination GO:0000209 110 0.017
ras protein signal transduction GO:0007265 73 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
positive regulation of locomotion GO:0040017 186 0.017
regulation of nuclease activity GO:0032069 11 0.017
natural killer cell differentiation GO:0001779 2 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
cellular protein catabolic process GO:0044257 261 0.017
negative regulation of cell death GO:0060548 345 0.017
detection of chemical stimulus GO:0009593 55 0.017
memory GO:0007613 3 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
response to organic cyclic compound GO:0014070 204 0.016
peripheral nervous system development GO:0007422 2 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
secretion by cell GO:0032940 226 0.016
positive regulation of developmental process GO:0051094 314 0.016
single organism membrane organization GO:0044802 268 0.016
negative regulation of protein maturation GO:1903318 142 0.016
purine nucleotide catabolic process GO:0006195 405 0.016
regulation of secretion by cell GO:1903530 177 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
negative regulation of developmental process GO:0051093 247 0.016
positive regulation of transferase activity GO:0051347 227 0.015
mapk cascade GO:0000165 288 0.015
regulation of proteolysis GO:0030162 293 0.015
regulation of protein secretion GO:0050708 86 0.015
positive regulation of kinase activity GO:0033674 204 0.015
chromatin organization GO:0006325 351 0.015
protein localization to membrane GO:0072657 160 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
positive regulation of secretion GO:0051047 116 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
regulation of cell cycle process GO:0010564 266 0.014
negative regulation of response to external stimulus GO:0032102 83 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
negative regulation of transport GO:0051051 176 0.014
cation transport GO:0006812 331 0.014
nervous system development GO:0007399 293 0.014
response to organonitrogen compound GO:0010243 156 0.014
nucleoside catabolic process GO:0009164 408 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
cardiovascular system development GO:0072358 262 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
maintenance of location GO:0051235 112 0.014
negative regulation of viral genome replication GO:0045071 35 0.014
hexose metabolic process GO:0019318 55 0.014
positive regulation of response to external stimulus GO:0032103 88 0.014
regulation of protein kinase activity GO:0045859 289 0.014
neurological system process GO:0050877 163 0.014
purine containing compound catabolic process GO:0072523 411 0.014
positive regulation of peptidase activity GO:0010952 88 0.014
protein lipidation GO:0006497 33 0.014
inorganic anion transport GO:0015698 60 0.014
regulation of metal ion transport GO:0010959 120 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
regulation of mapk cascade GO:0043408 262 0.014
negative regulation of defense response to virus by host GO:0050689 4 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
protein maturation GO:0051604 233 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
cell development GO:0048468 328 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
generation of neurons GO:0048699 152 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
regulation of cellular response to stress GO:0080135 244 0.013
circadian behavior GO:0048512 2 0.013
positive regulation of immune effector process GO:0002699 40 0.013
angiogenesis GO:0001525 147 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
tissue homeostasis GO:0001894 63 0.013
positive regulation of organelle organization GO:0010638 195 0.013
response to peptidoglycan GO:0032494 3 0.013
cellular lipid metabolic process GO:0044255 303 0.013
immune system development GO:0002520 195 0.013
activation of cysteine type endopeptidase activity GO:0097202 57 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
cellular homeostasis GO:0019725 196 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
epithelium development GO:0060429 227 0.013
negative regulation of intracellular protein transport GO:0090317 42 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
positive regulation of lymphocyte activation GO:0051251 73 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012
negative regulation of angiogenesis GO:0016525 39 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.012
regulation of vasculature development GO:1901342 97 0.012
lymphocyte activation GO:0046649 133 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
lipid metabolic process GO:0006629 381 0.012
cell cycle checkpoint GO:0000075 117 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
regulation of cellular component movement GO:0051270 334 0.012
rna catabolic process GO:0006401 71 0.012
endocytosis GO:0006897 159 0.012
regulation of cell activation GO:0050865 125 0.012
epithelial cell differentiation GO:0030855 141 0.012
positive regulation of endopeptidase activity GO:0010950 84 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
circulatory system development GO:0072359 262 0.012
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.012
regulation of cytokine biosynthetic process GO:0042035 35 0.012
locomotory behavior GO:0007626 1 0.012
protein processing GO:0016485 226 0.012
response to tumor necrosis factor GO:0034612 76 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of protein maturation GO:1903317 150 0.012
protein autoprocessing GO:0016540 4 0.011
positive regulation of t cell activation GO:0050870 54 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
dna repair GO:0006281 198 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
positive regulation of cell activation GO:0050867 81 0.011
lipid biosynthetic process GO:0008610 177 0.011
response to bacterium GO:0009617 144 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
autophagic cell death GO:0048102 3 0.011
blood vessel morphogenesis GO:0048514 162 0.011
cellular component morphogenesis GO:0032989 314 0.011
neuromuscular junction development GO:0007528 3 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
atp catabolic process GO:0006200 157 0.011
peptide metabolic process GO:0006518 51 0.011
carbohydrate homeostasis GO:0033500 31 0.011
sensory perception GO:0007600 103 0.011
cytokine metabolic process GO:0042107 38 0.011
regulation of cell adhesion GO:0030155 166 0.011
regulation of ion transport GO:0043269 189 0.011
regulation of chromosome organization GO:0033044 103 0.011
regulation of map kinase activity GO:0043405 108 0.011
neurogenesis GO:0022008 169 0.011
cellular response to interferon gamma GO:0071346 24 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
positive regulation of protein import into nucleus GO:0042307 46 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
response to uv GO:0009411 73 0.011
negative regulation of protein modification process GO:0031400 200 0.011
response to hormone GO:0009725 175 0.011
double strand break repair GO:0006302 101 0.011
negative regulation of protein import into nucleus GO:0042308 30 0.011
neuron differentiation GO:0030182 138 0.011
autophagy GO:0006914 88 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.010
membrane hyperpolarization GO:0060081 1 0.010
positive regulation of proteolysis GO:0045862 142 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
developmental programmed cell death GO:0010623 3 0.010
mitochondrion organization GO:0007005 156 0.010
divalent inorganic cation transport GO:0072511 158 0.010
interferon beta production GO:0032608 23 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
blood vessel development GO:0001568 172 0.010
vasculature development GO:0001944 181 0.010
regulation of protein catabolic process GO:0042176 155 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
toxin transport GO:1901998 4 0.010
rho protein signal transduction GO:0007266 26 0.010
positive regulation of mhc class i biosynthetic process GO:0045345 4 0.010

APOL6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.031
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
disease of metabolism DOID:0014667 295 0.017
acquired metabolic disease DOID:0060158 58 0.014
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012
gastrointestinal system cancer DOID:3119 52 0.012
cardiovascular system disease DOID:1287 106 0.011