Homo sapiens

7 known processes

HERPUD1

homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

(Aliases: SUP,KIAA0025,HERP,Mif1)

HERPUD1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to endoplasmic reticulum stress GO:0034976 49 0.954
Mouse
endoplasmic reticulum unfolded protein response GO:0030968 16 0.953
Mouse
cellular response to unfolded protein GO:0034620 16 0.859
Mouse
cellular response to topologically incorrect protein GO:0035967 19 0.806
Mouse
modification dependent protein catabolic process GO:0019941 209 0.720
Mouse
macromolecule glycosylation GO:0043413 63 0.677
modification dependent macromolecule catabolic process GO:0043632 212 0.642
Mouse
response to unfolded protein GO:0006986 24 0.629
protein catabolic process GO:0030163 325 0.628
Mouse
er nucleus signaling pathway GO:0006984 23 0.570
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.570
Mouse
response to oxygen containing compound GO:1901700 369 0.500
carbohydrate derivative biosynthetic process GO:1901137 207 0.482
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.460
negative regulation of cell death GO:0060548 345 0.448
response to topologically incorrect protein GO:0035966 29 0.434
proteasomal protein catabolic process GO:0010498 176 0.427
ubiquitin dependent protein catabolic process GO:0006511 206 0.389
Mouse
reactive nitrogen species metabolic process GO:2001057 3 0.388
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.308
Mouse
cellular protein catabolic process GO:0044257 261 0.300
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.286
post embryonic development GO:0009791 2 0.283
response to external biotic stimulus GO:0043207 261 0.269
apoptotic signaling pathway GO:0097190 268 0.233
reactive oxygen species metabolic process GO:0072593 75 0.232
single organism carbohydrate metabolic process GO:0044723 193 0.194
acute inflammatory response to antigenic stimulus GO:0002438 1 0.193
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.183
protein n linked glycosylation via asparagine GO:0018279 10 0.176
response to other organism GO:0051707 261 0.173
negative regulation of programmed cell death GO:0043069 321 0.170
response to lipid GO:0033993 206 0.166
response to biotic stimulus GO:0009607 276 0.164
regulation of acute inflammatory response to antigenic stimulus GO:0002864 1 0.162
regulation of secretion GO:0051046 194 0.154
intrinsic apoptotic signaling pathway GO:0097193 127 0.147
immune response GO:0006955 307 0.131
response to oxidative stress GO:0006979 121 0.120
negative regulation of apoptotic process GO:0043066 316 0.116
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.111
defense response GO:0006952 315 0.108
vesicle mediated transport GO:0016192 371 0.103
cell type specific apoptotic process GO:0097285 125 0.102
negative regulation of acute inflammatory response GO:0002674 3 0.097
cellular response to oxygen containing compound GO:1901701 276 0.092
positive regulation of catabolic process GO:0009896 310 0.091
cellular response to toxic substance GO:0097237 4 0.090
regulation of response to wounding GO:1903034 101 0.086
protein ubiquitination GO:0016567 314 0.086
Mouse
regulation of cellular component movement GO:0051270 334 0.085
cellular response to biotic stimulus GO:0071216 71 0.085
translation GO:0006412 132 0.085
inflammatory response to antigenic stimulus GO:0002437 4 0.084
retrograde protein transport er to cytosol GO:0030970 5 0.079
regulation of cytokine production GO:0001817 232 0.077
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 3 0.076
negative regulation of immune system process GO:0002683 136 0.076
negative regulation of immune response GO:0050777 40 0.074
regulation of acute inflammatory response GO:0002673 13 0.073
positive regulation of transport GO:0051050 336 0.072
purine ribonucleotide catabolic process GO:0009154 404 0.071
secretion GO:0046903 254 0.071
cytoplasmic transport GO:0016482 379 0.067
intracellular protein transport GO:0006886 270 0.067
regulation of response to external stimulus GO:0032101 222 0.066
secretion by cell GO:0032940 226 0.065
golgi vesicle transport GO:0048193 80 0.064
protein modification by small protein conjugation GO:0032446 342 0.063
Mouse
cellular response to nutrient levels GO:0031669 69 0.063
regulation of reactive oxygen species metabolic process GO:2000377 41 0.062
carbohydrate metabolic process GO:0005975 207 0.062
regulation of secretion by cell GO:1903530 177 0.061
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.060
negative regulation of protein metabolic process GO:0051248 391 0.060
positive regulation of secretion by cell GO:1903532 108 0.059
regulation of cellular response to stress GO:0080135 244 0.059
negative regulation of apoptotic signaling pathway GO:2001234 97 0.058
regulation of apoptotic signaling pathway GO:2001233 175 0.056
negative regulation of intracellular signal transduction GO:1902532 183 0.056
inflammatory response GO:0006954 79 0.055
hindbrain development GO:0030902 3 0.053
protein glycosylation GO:0006486 62 0.053
cellular response to lipopolysaccharide GO:0071222 57 0.053
posttranscriptional regulation of gene expression GO:0010608 213 0.050
regulation of leukocyte apoptotic process GO:2000106 25 0.050
metencephalon development GO:0022037 2 0.048
regulation of protein transport GO:0051223 213 0.048
positive regulation of protein catabolic process GO:0045732 75 0.048
lipid metabolic process GO:0006629 381 0.047
multicellular organismal aging GO:0010259 3 0.046
positive regulation of immune system process GO:0002684 283 0.046
cellular response to molecule of bacterial origin GO:0071219 62 0.046
regulation of immune response GO:0050776 201 0.045
determination of adult lifespan GO:0008340 2 0.045
cellular response to oxidative stress GO:0034599 85 0.044
regulation of proteolysis GO:0030162 293 0.044
skeletal system development GO:0001501 79 0.043
cellular ketone metabolic process GO:0042180 80 0.043
cation transport GO:0006812 331 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.042
purine ribonucleoside catabolic process GO:0046130 398 0.042
ribonucleoside catabolic process GO:0042454 406 0.042
single organism cellular localization GO:1902580 332 0.042
cellular response to antibiotic GO:0071236 1 0.042
cellular response to lipid GO:0071396 127 0.041
positive regulation of secretion GO:0051047 116 0.041
leukocyte apoptotic process GO:0071887 31 0.040
regulation of protein secretion GO:0050708 86 0.040
system process GO:0003008 349 0.040
mrna metabolic process GO:0016071 175 0.040
regulation of leukocyte activation GO:0002694 115 0.040
positive regulation of cellular catabolic process GO:0031331 284 0.040
ribonucleotide catabolic process GO:0009261 405 0.039
negative regulation of response to wounding GO:1903035 47 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.038
protein processing GO:0016485 226 0.038
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
acute inflammatory response GO:0002526 21 0.038
inflammatory cell apoptotic process GO:0006925 3 0.037
hexose metabolic process GO:0019318 55 0.036
regulation of cell migration GO:0030334 289 0.036
nucleoside catabolic process GO:0009164 408 0.036
regulation of inflammatory response GO:0050727 46 0.036
female gamete generation GO:0007292 2 0.036
neurotransmitter secretion GO:0007269 4 0.035
positive regulation of phosphorylation GO:0042327 394 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
response to abiotic stimulus GO:0009628 336 0.034
positive regulation of transferase activity GO:0051347 227 0.033
protein localization to organelle GO:0033365 280 0.033
regulation of cellular component biogenesis GO:0044087 281 0.033
negative regulation of cellular component organization GO:0051129 235 0.033
response to molecule of bacterial origin GO:0002237 82 0.033
response to nitrogen compound GO:1901698 184 0.032
glycoprotein metabolic process GO:0009100 110 0.032
serotonin transport GO:0006837 3 0.032
maintenance of location in cell GO:0051651 62 0.031
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
positive regulation of developmental process GO:0051094 314 0.031
regulation of cell activation GO:0050865 125 0.030
positive regulation of cell differentiation GO:0045597 211 0.030
cellular response to endogenous stimulus GO:0071495 336 0.030
response to hexose GO:0009746 20 0.030
regulation of transferase activity GO:0051338 355 0.029
regulation of cytokine secretion GO:0050707 57 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
response to disaccharide GO:0034285 1 0.029
purine nucleoside triphosphate catabolic process GO:0009146 392 0.028
negative regulation of hydrolase activity GO:0051346 182 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
positive regulation of organ growth GO:0046622 2 0.028
regulation of purine nucleotide catabolic process GO:0033121 205 0.028
monocarboxylic acid metabolic process GO:0032787 185 0.028
positive regulation of protein secretion GO:0050714 60 0.028
negative regulation of multicellular organismal process GO:0051241 317 0.027
response to bacterium GO:0009617 144 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
rna interference GO:0016246 4 0.027
maintenance of location GO:0051235 112 0.026
mitotic cell cycle GO:0000278 326 0.026
actin filament based process GO:0030029 224 0.026
response to lipopolysaccharide GO:0032496 70 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
negative regulation of cell proliferation GO:0008285 228 0.025
organophosphate catabolic process GO:0046434 430 0.025
regulation of kinase activity GO:0043549 314 0.025
response to fungus GO:0009620 4 0.025
regulation of nucleotide metabolic process GO:0006140 269 0.025
response to cytokine GO:0034097 232 0.025
protein maturation GO:0051604 233 0.025
oogenesis GO:0048477 2 0.025
gtp catabolic process GO:0006184 237 0.024
purine containing compound catabolic process GO:0072523 411 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
cellular response to external stimulus GO:0071496 111 0.023
nitrogen compound transport GO:0071705 191 0.023
response to redox state GO:0051775 7 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
leukocyte activation GO:0045321 164 0.023
rna processing GO:0006396 255 0.023
positive regulation of protein kinase activity GO:0045860 190 0.022
negative regulation of response to external stimulus GO:0032102 83 0.022
regulation of translation GO:0006417 89 0.022
response to starvation GO:0042594 59 0.022
monovalent inorganic cation transport GO:0015672 128 0.022
cerebellum development GO:0021549 2 0.022
cell growth GO:0016049 160 0.022
cellular homeostasis GO:0019725 196 0.021
regulation of protein maturation GO:1903317 150 0.021
protein oligomerization GO:0051259 173 0.021
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
embryo development GO:0009790 123 0.021
glucose metabolic process GO:0006006 45 0.021
positive regulation of cytokine production GO:0001819 167 0.021
segmentation GO:0035282 4 0.021
positive regulation of kinase activity GO:0033674 204 0.021
regulation of cell differentiation GO:0045595 393 0.021
chemical homeostasis GO:0048878 306 0.021
response to misfolded protein GO:0051788 5 0.021
regulation of muscle organ development GO:0048634 27 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
negative regulation of developmental process GO:0051093 247 0.021
serotonin secretion GO:0001820 1 0.020
epithelial cell proliferation GO:0050673 128 0.020
adult locomotory behavior GO:0008344 1 0.020
regulation of cell motility GO:2000145 299 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
cellular response to cytokine stimulus GO:0071345 181 0.020
protein homooligomerization GO:0051260 100 0.020
positive regulation of endothelial cell differentiation GO:0045603 2 0.020
cell development GO:0048468 328 0.020
cellular response to organonitrogen compound GO:0071417 124 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
negative regulation of defense response GO:0031348 47 0.020
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.020
gtp metabolic process GO:0046039 239 0.019
response to wounding GO:0009611 168 0.019
lymphocyte activation GO:0046649 133 0.019
epithelial cell differentiation GO:0030855 141 0.019
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.019
glycoprotein biosynthetic process GO:0009101 91 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
response to extracellular stimulus GO:0009991 85 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
positive regulation of cellular protein catabolic process GO:1903364 37 0.019
regulation of protein kinase activity GO:0045859 289 0.019
fatty acid metabolic process GO:0006631 115 0.019
positive regulation of organelle organization GO:0010638 195 0.019
mitotic cell cycle process GO:1903047 286 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
glycosylation GO:0070085 71 0.018
signal release GO:0023061 70 0.018
regulation of growth GO:0040008 165 0.018
cellular response to starvation GO:0009267 58 0.018
rna catabolic process GO:0006401 71 0.018
regulation of cell development GO:0060284 161 0.018
single organism membrane organization GO:0044802 268 0.018
response to peptide GO:1901652 65 0.018
positive regulation of cell death GO:0010942 263 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
ras protein signal transduction GO:0007265 73 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
blood vessel development GO:0001568 172 0.018
regulation of gtpase activity GO:0043087 180 0.017
positive regulation of lymphocyte activation GO:0051251 73 0.017
positive regulation of cell migration GO:0030335 172 0.017
cellular cation homeostasis GO:0030003 163 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
positive regulation of leukocyte activation GO:0002696 80 0.017
cell activation GO:0001775 213 0.017
immune effector process GO:0002252 159 0.017
positive regulation of programmed cell death GO:0043068 249 0.017
positive regulation of protein transport GO:0051222 135 0.016
regulation of protein catabolic process GO:0042176 155 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
cytokine secretion GO:0050663 64 0.016
activation of signaling protein activity involved in unfolded protein response GO:0006987 3 0.016
ion homeostasis GO:0050801 230 0.016
chondrocyte development GO:0002063 1 0.016
regulation of defense response GO:0031347 154 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
regulation of membrane potential GO:0042391 95 0.016
metal ion transport GO:0030001 272 0.016
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.016
cellular chemical homeostasis GO:0055082 180 0.016
negative regulation of protein maturation GO:1903318 142 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
peptidyl asparagine modification GO:0018196 11 0.016
cytokine production GO:0001816 247 0.016
regulation of protein complex assembly GO:0043254 147 0.015
regulation of locomotion GO:0040012 329 0.015
cell projection assembly GO:0030031 126 0.015
hemopoiesis GO:0030097 180 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
growth hormone secretion GO:0030252 4 0.015
regulation of immunoglobulin production GO:0002637 4 0.015
positive regulation of immune response GO:0050778 159 0.015
regulation of endothelial cell differentiation GO:0045601 4 0.015
cellular ion homeostasis GO:0006873 168 0.015
regulation of protein localization GO:0032880 296 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
cellular response to extracellular stimulus GO:0031668 72 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
cellular lipid metabolic process GO:0044255 303 0.015
monosaccharide metabolic process GO:0005996 74 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
response to organonitrogen compound GO:0010243 156 0.015
response to hormone GO:0009725 175 0.015
nucleotide catabolic process GO:0009166 408 0.014
single organism reproductive process GO:0044702 98 0.014
amine metabolic process GO:0009308 44 0.014
neurological system process GO:0050877 163 0.014
organic acid transport GO:0015849 65 0.014
regulation of metal ion transport GO:0010959 120 0.014
plasma membrane organization GO:0007009 115 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
regeneration GO:0031099 4 0.014
organelle fission GO:0048285 149 0.014
negative regulation of neurological system process GO:0031645 2 0.014
positive regulation of cell cycle GO:0045787 140 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
negative regulation of protein modification process GO:0031400 200 0.014
regulation of cell cycle GO:0051726 393 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
response to nutrient levels GO:0031667 81 0.014
regulation of intracellular transport GO:0032386 195 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
dephosphorylation GO:0016311 209 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
regulation of insulin secretion GO:0050796 33 0.013
cerebellar cortex development GO:0021695 1 0.013
regulation of dna metabolic process GO:0051052 153 0.013
tissue regeneration GO:0042246 3 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
response to decreased oxygen levels GO:0036293 96 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
cellular response to insulin stimulus GO:0032869 41 0.013
positive regulation of t cell activation GO:0050870 54 0.013
regulation of t cell activation GO:0050863 77 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
glial cell migration GO:0008347 4 0.013
interleukin 6 production GO:0032635 37 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
oxidation reduction process GO:0055114 396 0.013
peptidyl lysine modification GO:0018205 144 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
microtubule based process GO:0007017 210 0.012
epidermis morphogenesis GO:0048730 3 0.012
biological adhesion GO:0022610 331 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.012
mrna catabolic process GO:0006402 56 0.012
transmembrane transport GO:0055085 399 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
regulation of cell cycle process GO:0010564 266 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of cell growth GO:0001558 135 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
peripheral nervous system development GO:0007422 2 0.012
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.012
response to inorganic substance GO:0010035 127 0.012
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.012
protein secretion GO:0009306 98 0.012
regulation of protein processing GO:0070613 150 0.012
nitric oxide metabolic process GO:0046209 22 0.012
hepatocyte proliferation GO:0072574 1 0.012
aging GO:0007568 66 0.012
t cell activation GO:0042110 99 0.012
regulation of lymphocyte proliferation GO:0050670 64 0.012
cdc42 protein signal transduction GO:0032488 4 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.011
cellular component morphogenesis GO:0032989 314 0.011
positive regulation of locomotion GO:0040017 186 0.011
protein import GO:0017038 130 0.011
response to electrical stimulus GO:0051602 1 0.011
positive regulation of lipase activity GO:0060193 28 0.011
t cell proliferation GO:0042098 45 0.011
protein polymerization GO:0051258 71 0.011
response to organic cyclic compound GO:0014070 204 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
circulatory system development GO:0072359 262 0.011
positive regulation of epithelial cell proliferation GO:0050679 65 0.011
positive regulation of proteolysis GO:0045862 142 0.011
second messenger mediated signaling GO:0019932 78 0.011
protein targeting to membrane GO:0006612 42 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
regulation of actin filament based process GO:0032970 141 0.011
muscle organ development GO:0007517 56 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
rho protein signal transduction GO:0007266 26 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
cation homeostasis GO:0055080 189 0.011
sex differentiation GO:0007548 45 0.011
compound eye development GO:0048749 1 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
protein localization to membrane GO:0072657 160 0.011
reproductive structure development GO:0048608 55 0.011
amino acid transport GO:0006865 28 0.011
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
regulation of chromosome organization GO:0033044 103 0.011
chromosome segregation GO:0007059 114 0.010
regulation of microtubule cytoskeleton organization GO:0070507 61 0.010
rac protein signal transduction GO:0016601 12 0.010
membrane organization GO:0061024 292 0.010
histone serine phosphorylation GO:0035404 4 0.010
positive regulation of cytokine secretion GO:0050715 42 0.010
muscle structure development GO:0061061 98 0.010
negative regulation of protein processing GO:0010955 142 0.010
response to hypoxia GO:0001666 96 0.010
ventral spinal cord development GO:0021517 1 0.010
regulation of carbohydrate metabolic process GO:0006109 54 0.010
negative regulation of leukocyte apoptotic process GO:2000107 16 0.010
interleukin 8 production GO:0032637 51 0.010
regulation of homeostatic process GO:0032844 121 0.010
tripartite regional subdivision GO:0007351 2 0.010
lipid localization GO:0010876 106 0.010
cellular response to glucocorticoid stimulus GO:0071385 4 0.010
positive regulation of leukocyte differentiation GO:1902107 37 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
regulation of angiogenesis GO:0045765 92 0.010
regulation of mhc class ii biosynthetic process GO:0045346 4 0.010
developmental programmed cell death GO:0010623 3 0.010

HERPUD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.049
nervous system disease DOID:863 431 0.049
disease of metabolism DOID:0014667 295 0.027
cardiovascular system disease DOID:1287 106 0.020
disease of cellular proliferation DOID:14566 174 0.020
cancer DOID:162 167 0.016
inherited metabolic disorder DOID:655 242 0.015
organ system cancer DOID:0050686 164 0.014
muscular disease DOID:0080000 114 0.013
musculoskeletal system disease DOID:17 223 0.013
muscle tissue disease DOID:66 113 0.013
heart disease DOID:114 68 0.010