Homo sapiens

38 known processes

NDNL2

necdin-like 2

(Aliases: HCA4,MAGEL3,MAGEG1,NSE3,NSMCE3)

NDNL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.860
positive regulation of response to dna damage stimulus GO:2001022 43 0.338
protein ubiquitination GO:0016567 314 0.203
regulation of response to dna damage stimulus GO:2001020 94 0.201
cellular response to dna damage stimulus GO:0006974 379 0.138
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.134
regulation of cellular response to stress GO:0080135 244 0.102
protein catabolic process GO:0030163 325 0.089
Human
regulation of transferase activity GO:0051338 355 0.057
Human
negative regulation of protein metabolic process GO:0051248 391 0.050
Human
cellular amino acid metabolic process GO:0006520 116 0.050
signal transduction by phosphorylation GO:0023014 297 0.049
regulation of kinase activity GO:0043549 314 0.048
post embryonic development GO:0009791 2 0.045
positive regulation of protein phosphorylation GO:0001934 313 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
amine metabolic process GO:0009308 44 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.040
cellular amine metabolic process GO:0044106 41 0.039
regulation of cell cycle GO:0051726 393 0.039
determination of adult lifespan GO:0008340 2 0.038
regulation of proteolysis GO:0030162 293 0.038
cellular ketone metabolic process GO:0042180 80 0.037
response to organonitrogen compound GO:0010243 156 0.036
double strand break repair via homologous recombination GO:0000724 50 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
multicellular organismal aging GO:0010259 3 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
apoptotic signaling pathway GO:0097190 268 0.031
segmentation GO:0035282 4 0.031
response to caffeine GO:0031000 3 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
cellular macromolecule catabolic process GO:0044265 380 0.029
Human
regulation of mapk cascade GO:0043408 262 0.028
mitotic cell cycle phase transition GO:0044772 162 0.027
organophosphate catabolic process GO:0046434 430 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
purine nucleotide catabolic process GO:0006195 405 0.026
positive regulation of developmental process GO:0051094 314 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
positive regulation of phosphorylation GO:0042327 394 0.026
mapk cascade GO:0000165 288 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
neuromuscular junction development GO:0007528 3 0.025
positive regulation of apoptotic process GO:0043065 246 0.025
immune response GO:0006955 307 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.024
positive regulation of cell death GO:0010942 263 0.024
oogenesis GO:0048477 2 0.024
cell aging GO:0007569 52 0.024
Human
locomotory behavior GO:0007626 1 0.024
positive regulation of mapk cascade GO:0043410 190 0.023
positive regulation of programmed cell death GO:0043068 249 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
female gamete generation GO:0007292 2 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
epithelium development GO:0060429 227 0.023
organelle fission GO:0048285 149 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
ribonucleotide catabolic process GO:0009261 405 0.022
double strand break repair GO:0006302 101 0.022
cytoplasmic transport GO:0016482 379 0.022
regulation of cell cycle phase transition GO:1901987 126 0.022
protein maturation GO:0051604 233 0.022
negative regulation of cellular protein metabolic process GO:0032269 353 0.022
Human
anterior posterior axis specification GO:0009948 2 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
cellular senescence GO:0090398 34 0.021
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
histone modification GO:0016570 251 0.020
memory GO:0007613 3 0.020
positive regulation of synaptic transmission GO:0050806 4 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
purine containing compound catabolic process GO:0072523 411 0.020
transmembrane transport GO:0055085 399 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
covalent chromatin modification GO:0016569 254 0.020
chemical homeostasis GO:0048878 306 0.020
ras protein signal transduction GO:0007265 73 0.020
response to oxygen containing compound GO:1901700 369 0.019
regulation of protein serine threonine kinase activity GO:0071900 179 0.019
response to nitrogen compound GO:1901698 184 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
response to abiotic stimulus GO:0009628 336 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
intracellular protein transport GO:0006886 270 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
nucleotide catabolic process GO:0009166 408 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
microtubule based process GO:0007017 210 0.019
single organism cellular localization GO:1902580 332 0.019
cation transport GO:0006812 331 0.019
mitotic sister chromatid segregation GO:0000070 53 0.019
regulation of protein kinase activity GO:0045859 289 0.019
regeneration GO:0031099 4 0.019
protein processing GO:0016485 226 0.018
positive regulation of transport GO:0051050 336 0.018
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.018
regulation of protein localization GO:0032880 296 0.018
response to external biotic stimulus GO:0043207 261 0.018
organelle assembly GO:0070925 176 0.018
hindbrain development GO:0030902 3 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
regulation of cellular component movement GO:0051270 334 0.018
defense response GO:0006952 315 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
cellular protein complex assembly GO:0043623 188 0.017
ion homeostasis GO:0050801 230 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
cellular component morphogenesis GO:0032989 314 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
cell adhesion GO:0007155 325 0.017
dephosphorylation GO:0016311 209 0.017
positive regulation of transferase activity GO:0051347 227 0.017
Human
positive regulation of proteolysis GO:0045862 142 0.017
innate immune response GO:0045087 178 0.017
regulation of chromosome segregation GO:0051983 44 0.017
negative regulation of cell cycle GO:0045786 193 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
lipid metabolic process GO:0006629 381 0.017
negative regulation of protein modification process GO:0031400 200 0.017
Human
regulation of establishment of protein localization GO:0070201 242 0.017
associative learning GO:0008306 1 0.017
chromatin modification GO:0016568 298 0.017
telomere organization GO:0032200 33 0.017
regulation of protein transport GO:0051223 213 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
adult locomotory behavior GO:0008344 1 0.017
negative regulation of cell death GO:0060548 345 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
blastoderm segmentation GO:0007350 2 0.017
system process GO:0003008 349 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.016
tripartite regional subdivision GO:0007351 2 0.016
rho protein signal transduction GO:0007266 26 0.016
actin filament based process GO:0030029 224 0.016
telomere maintenance via recombination GO:0000722 4 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
positive regulation of immune system process GO:0002684 283 0.016
carbohydrate metabolic process GO:0005975 207 0.016
membrane organization GO:0061024 292 0.016
regulation of secretion GO:0051046 194 0.016
cytokine production GO:0001816 247 0.016
secretion by cell GO:0032940 226 0.016
response to cytokine GO:0034097 232 0.016
secretion GO:0046903 254 0.016
rna processing GO:0006396 255 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
positive regulation of mesonephros development GO:0061213 2 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
neurotransmitter secretion GO:0007269 4 0.016
regulation of locomotion GO:0040012 329 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
cell morphogenesis GO:0000902 296 0.016
metencephalon development GO:0022037 2 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
mitotic sister chromatid separation GO:0051306 18 0.016
negative regulation of programmed cell death GO:0043069 321 0.015
negative regulation of protein processing GO:0010955 142 0.015
regulation of response to external stimulus GO:0032101 222 0.015
biological adhesion GO:0022610 331 0.015
nucleoside catabolic process GO:0009164 408 0.015
peripheral nervous system development GO:0007422 2 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.015
gtp metabolic process GO:0046039 239 0.015
ribonucleoside catabolic process GO:0042454 406 0.015
regulation of cell motility GO:2000145 299 0.015
oocyte development GO:0048599 1 0.015
response to lipid GO:0033993 206 0.015
regulation of mesonephros development GO:0061217 3 0.015
nerve development GO:0021675 4 0.015
small molecule biosynthetic process GO:0044283 157 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
cardiac muscle cell contraction GO:0086003 4 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
response to growth factor GO:0070848 205 0.015
single organism membrane organization GO:0044802 268 0.015
response to biotic stimulus GO:0009607 276 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
oocyte differentiation GO:0009994 2 0.014
peptidyl lysine modification GO:0018205 144 0.014
regulation of cytokine production GO:0001817 232 0.014
interspecies interaction between organisms GO:0044419 156 0.014
gtp catabolic process GO:0006184 237 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
cell projection organization GO:0030030 252 0.014
methylation GO:0032259 106 0.014
chromatin organization GO:0006325 351 0.014
monocarboxylic acid metabolic process GO:0032787 185 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
lipid biosynthetic process GO:0008610 177 0.014
circadian behavior GO:0048512 2 0.014
protein targeting GO:0006605 187 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
organ formation GO:0048645 3 0.014
nitrogen compound transport GO:0071705 191 0.014
metaphase anaphase transition of cell cycle GO:0044784 21 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of cell differentiation GO:0045595 393 0.014
sequestering of metal ion GO:0051238 24 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
cellular protein catabolic process GO:0044257 261 0.013
Human
response to fungus GO:0009620 4 0.013
regulation of cell migration GO:0030334 289 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
sensory perception of pain GO:0019233 4 0.013
regulation of ion transport GO:0043269 189 0.013
metal ion transport GO:0030001 272 0.013
protein kinase a signaling GO:0010737 9 0.013
cellular lipid metabolic process GO:0044255 303 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
neurological system process GO:0050877 163 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
response to other organism GO:0051707 261 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
maintenance of location GO:0051235 112 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
sequestering of calcium ion GO:0051208 17 0.013
inner ear morphogenesis GO:0042472 4 0.013
cellular ion homeostasis GO:0006873 168 0.013
cell fate determination GO:0001709 3 0.013
cellular cation homeostasis GO:0030003 163 0.013
cellular chemical homeostasis GO:0055082 180 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
stem cell division GO:0017145 2 0.013
regulation of secretion by cell GO:1903530 177 0.013
protein localization to membrane GO:0072657 160 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
cation homeostasis GO:0055080 189 0.013
compound eye development GO:0048749 1 0.013
motor neuron axon guidance GO:0008045 2 0.013
response to axon injury GO:0048678 1 0.013
negative regulation of protein maturation GO:1903318 142 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
regulation of protein processing GO:0070613 150 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
cell activation GO:0001775 213 0.013
nephron epithelium morphogenesis GO:0072088 15 0.013
negative regulation of proteolysis GO:0045861 132 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
cell growth GO:0016049 160 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
neuroblast proliferation GO:0007405 4 0.013
regulation of neurotransmitter secretion GO:0046928 3 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
ion transmembrane transport GO:0034220 338 0.012
nervous system development GO:0007399 293 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
mitotic recombination GO:0006312 8 0.012
divalent inorganic cation transport GO:0072511 158 0.012
salivary gland morphogenesis GO:0007435 4 0.012
divalent metal ion transport GO:0070838 152 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.012
regulation of intracellular transport GO:0032386 195 0.012
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.012
mating GO:0007618 1 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
glycoprotein metabolic process GO:0009100 110 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of immune response GO:0050776 201 0.012
visual behavior GO:0007632 2 0.012
tissue regeneration GO:0042246 3 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
multi organism cellular process GO:0044764 156 0.012
behavioral response to ethanol GO:0048149 2 0.012
regulation of protein complex assembly GO:0043254 147 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
calcium ion transport GO:0006816 147 0.012
cell development GO:0048468 328 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
single organism cell adhesion GO:0098602 179 0.012
long term memory GO:0007616 2 0.012
protein autophosphorylation GO:0046777 123 0.012
mitochondrion organization GO:0007005 156 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
cerebellum development GO:0021549 2 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
defense response to fungus GO:0050832 4 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
actin mediated cell contraction GO:0070252 12 0.012
meiosis i GO:0007127 4 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.011
somitogenesis GO:0001756 2 0.011
myoblast fusion GO:0007520 1 0.011
cation transmembrane transport GO:0098655 238 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
spermatid development GO:0007286 4 0.011
negative regulation of transport GO:0051051 176 0.011
limbic system development GO:0021761 3 0.011
regulation of cell growth GO:0001558 135 0.011
actin filament based movement GO:0030048 17 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of multi organism process GO:0043900 157 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
cardiovascular system development GO:0072358 262 0.011
regulation of homeostatic process GO:0032844 121 0.011
regulation of protein maturation GO:1903317 150 0.011
macromolecule methylation GO:0043414 97 0.011
t cell differentiation in thymus GO:0033077 4 0.011
actin cytoskeleton organization GO:0030036 207 0.011
positive regulation of cell migration GO:0030335 172 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
negative regulation of developmental process GO:0051093 247 0.011
protein localization to nucleus GO:0034504 136 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
protein alkylation GO:0008213 74 0.011
specification of organ identity GO:0010092 3 0.011
protein acylation GO:0043543 138 0.011
Human
organic acid biosynthetic process GO:0016053 97 0.011
cell part morphogenesis GO:0032990 137 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
regulation of peptidase activity GO:0052547 180 0.011
spinal cord development GO:0021510 4 0.011
rna splicing GO:0008380 131 0.011
rna interference GO:0016246 4 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
negative regulation of transferase activity GO:0051348 124 0.011
histone acetylation GO:0016573 93 0.011
synaptic transmission cholinergic GO:0007271 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
epithelial cell differentiation GO:0030855 141 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
epidermis morphogenesis GO:0048730 3 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
metal ion homeostasis GO:0055065 169 0.011
circulatory system development GO:0072359 262 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
cellular response to nitrogen compound GO:1901699 144 0.010
mrna processing GO:0006397 133 0.010
negative regulation of synaptic transmission GO:0050805 2 0.010
thymus development GO:0048538 3 0.010
vasculature development GO:0001944 181 0.010
negative regulation of immune system process GO:0002683 136 0.010
protein import GO:0017038 130 0.010
cellular homeostasis GO:0019725 196 0.010
developmental programmed cell death GO:0010623 3 0.010
lung alveolus development GO:0048286 4 0.010
regulation of transcription during mitosis GO:0045896 2 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
leukocyte activation GO:0045321 164 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
viral process GO:0016032 146 0.010
growth GO:0040007 202 0.010
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.010
establishment of tissue polarity GO:0007164 3 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
response to hormone GO:0009725 175 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
cell projection assembly GO:0030031 126 0.010
tube closure GO:0060606 3 0.010

NDNL2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.032
musculoskeletal system disease DOID:17 223 0.029
inherited metabolic disorder DOID:655 242 0.022
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
central nervous system disease DOID:331 186 0.019
connective tissue disease DOID:65 109 0.017
disease of cellular proliferation DOID:14566 174 0.017
immune system disease DOID:2914 155 0.016
cancer DOID:162 167 0.016
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.015
organ system cancer DOID:0050686 164 0.015
myopathy DOID:423 104 0.014
neurodegenerative disease DOID:1289 102 0.013
retinal disease DOID:5679 118 0.013
cardiovascular system disease DOID:1287 106 0.013
brain disease DOID:936 73 0.012
bone disease DOID:0080001 88 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011
retinal degeneration DOID:8466 89 0.011
hematopoietic system disease DOID:74 100 0.011
disease of mental health DOID:150 70 0.010
muscular dystrophy DOID:9884 51 0.010