Homo sapiens

72 known processes

BRD2

bromodomain containing 2

(Aliases: KIAA9001,NAT,FSH,RING3,D6S113E,FLJ31942,FSRG1,DKFZp686N0336,RNF3)

BRD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 298 0.380
Human
rna processing GO:0006396 255 0.295
post embryonic development GO:0009791 2 0.213
Worm Fly
mrna metabolic process GO:0016071 175 0.194
chromatin organization GO:0006325 351 0.183
segmentation GO:0035282 4 0.148
Fly
covalent chromatin modification GO:0016569 254 0.130
cytoplasmic transport GO:0016482 379 0.123
purine ribonucleoside catabolic process GO:0046130 398 0.121
histone h3 k27 demethylation GO:0071557 3 0.121
cellular macromolecular complex assembly GO:0034622 324 0.114
dna conformation change GO:0071103 113 0.110
protein ubiquitination GO:0016567 314 0.109
histone methylation GO:0016571 60 0.095
hemopoiesis GO:0030097 180 0.092
protein modification by small protein conjugation GO:0032446 342 0.091
rna splicing GO:0008380 131 0.089
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.088
determination of adult lifespan GO:0008340 2 0.084
purine ribonucleotide catabolic process GO:0009154 404 0.077
multicellular organismal aging GO:0010259 3 0.074
protein dna complex subunit organization GO:0071824 80 0.074
histone modification GO:0016570 251 0.072
purine ribonucleoside metabolic process GO:0046128 437 0.068
nucleotide catabolic process GO:0009166 408 0.065
cellular macromolecule catabolic process GO:0044265 380 0.063
ribonucleoside triphosphate catabolic process GO:0009203 391 0.063
mrna processing GO:0006397 133 0.063
glycosyl compound catabolic process GO:1901658 413 0.062
purine nucleotide catabolic process GO:0006195 405 0.062
nucleoside triphosphate metabolic process GO:0009141 422 0.061
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.060
nucleoside catabolic process GO:0009164 408 0.055
mitotic cell cycle process GO:1903047 286 0.055
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.055
nucleoside triphosphate catabolic process GO:0009143 394 0.055
blastoderm segmentation GO:0007350 2 0.054
Fly
small gtpase mediated signal transduction GO:0007264 78 0.054
chromatin assembly GO:0031497 61 0.052
purine containing compound catabolic process GO:0072523 411 0.051
cellular amine metabolic process GO:0044106 41 0.049
cell fate determination GO:0001709 3 0.049
mrna splicing via spliceosome GO:0000398 89 0.049
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
ribonucleoside catabolic process GO:0042454 406 0.049
negative regulation of apoptotic process GO:0043066 316 0.047
amine metabolic process GO:0009308 44 0.046
nucleocytoplasmic transport GO:0006913 176 0.046
mitotic cell cycle GO:0000278 326 0.045
Human
negative regulation of programmed cell death GO:0043069 321 0.045
cellular amino acid metabolic process GO:0006520 116 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.044
hematopoietic or lymphoid organ development GO:0048534 186 0.044
nucleosome organization GO:0034728 66 0.044
secretion by cell GO:0032940 226 0.042
ras protein signal transduction GO:0007265 73 0.042
negative regulation of cell death GO:0060548 345 0.042
immune system development GO:0002520 195 0.042
cell cycle phase transition GO:0044770 173 0.042
Human
growth GO:0040007 202 0.042
demethylation GO:0070988 37 0.041
cranial nerve development GO:0021545 4 0.040
regulation of cell differentiation GO:0045595 393 0.040
purine nucleoside monophosphate metabolic process GO:0009126 186 0.040
positive regulation of developmental process GO:0051094 314 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
nerve development GO:0021675 4 0.039
ribonucleoside monophosphate metabolic process GO:0009161 187 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
nitrogen compound transport GO:0071705 191 0.037
cellular protein catabolic process GO:0044257 261 0.036
female gamete generation GO:0007292 2 0.036
defense response to fungus GO:0050832 4 0.036
chromatin assembly or disassembly GO:0006333 78 0.036
leukocyte differentiation GO:0002521 98 0.035
cellular ketone metabolic process GO:0042180 80 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
dna packaging GO:0006323 77 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
modification dependent macromolecule catabolic process GO:0043632 212 0.032
secretion GO:0046903 254 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.031
neurogenesis GO:0022008 169 0.031
Worm
protein catabolic process GO:0030163 325 0.030
locomotory behavior GO:0007626 1 0.030
negative regulation of transport GO:0051051 176 0.030
dna repair GO:0006281 198 0.030
histone lysine methylation GO:0034968 50 0.030
positive regulation of immune system process GO:0002684 283 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
protein alkylation GO:0008213 74 0.029
atp metabolic process GO:0046034 176 0.028
negative regulation of immune system process GO:0002683 136 0.028
nucleoside monophosphate catabolic process GO:0009125 159 0.028
regulation of cell cycle GO:0051726 393 0.028
Human
regulation of gene expression epigenetic GO:0040029 73 0.028
negative regulation of cell differentiation GO:0045596 171 0.027
wnt signaling pathway GO:0016055 156 0.027
methylation GO:0032259 106 0.027
anterior posterior axis specification embryo GO:0008595 2 0.027
Fly
regulation of mitotic cell cycle GO:0007346 189 0.027
Human
tripartite regional subdivision GO:0007351 2 0.027
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.026
inner ear morphogenesis GO:0042472 4 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
cell cycle checkpoint GO:0000075 117 0.026
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.025
regulation of cell cycle process GO:0010564 266 0.025
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
response to abiotic stimulus GO:0009628 336 0.024
regulation of transferase activity GO:0051338 355 0.024
intracellular protein transport GO:0006886 270 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.024
organophosphate catabolic process GO:0046434 430 0.023
defense response GO:0006952 315 0.023
Human
microtubule based process GO:0007017 210 0.023
nervous system development GO:0007399 293 0.023
Worm
organ morphogenesis GO:0009887 147 0.023
Fly
negative regulation of cell cycle GO:0045786 193 0.023
Human
negative regulation of protein metabolic process GO:0051248 391 0.022
embryo development GO:0009790 123 0.022
Worm Fly
oogenesis GO:0048477 2 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
Human
regulation of nucleotide metabolic process GO:0006140 269 0.022
single organism cellular localization GO:1902580 332 0.022
generation of neurons GO:0048699 152 0.022
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
epithelium development GO:0060429 227 0.022
regulation of secretion by cell GO:1903530 177 0.022
regulation of response to external stimulus GO:0032101 222 0.022
Human
response to external biotic stimulus GO:0043207 261 0.022
regeneration GO:0031099 4 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.021
rna splicing via transesterification reactions GO:0000375 90 0.021
vesicle mediated transport GO:0016192 371 0.021
nuclear export GO:0051168 69 0.021
cellular component morphogenesis GO:0032989 314 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.021
regulation of secretion GO:0051046 194 0.021
immune response GO:0006955 307 0.021
chemical homeostasis GO:0048878 306 0.021
regulation of myeloid cell differentiation GO:0045637 81 0.020
positive regulation of catabolic process GO:0009896 310 0.020
regulation of rna splicing GO:0043484 62 0.020
regulation of response to dna damage stimulus GO:2001020 94 0.020
Human
regulation of mitotic cell cycle phase transition GO:1901990 118 0.020
Human
regulation of growth GO:0040008 165 0.020
gtp catabolic process GO:0006184 237 0.020
response to other organism GO:0051707 261 0.020
cell morphogenesis GO:0000902 296 0.019
positive regulation of organ growth GO:0046622 2 0.019
reproductive process GO:0022414 106 0.019
innate immune response GO:0045087 178 0.019
histone h3 k4 demethylation GO:0034720 4 0.019
myeloid cell differentiation GO:0030099 117 0.019
peripheral nervous system development GO:0007422 2 0.019
regulation of cellular response to stress GO:0080135 244 0.019
Human
compound eye development GO:0048749 1 0.018
histone lysine demethylation GO:0070076 14 0.018
positive regulation of nucleotide metabolic process GO:0045981 230 0.018
regulation of mrna metabolic process GO:1903311 53 0.018
neuromuscular junction development GO:0007528 3 0.018
protein methylation GO:0006479 74 0.018
establishment of rna localization GO:0051236 39 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
neuron differentiation GO:0030182 138 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
nuclear transport GO:0051169 179 0.017
cell activation GO:0001775 213 0.017
regionalization GO:0003002 29 0.017
Fly
regulation of protein kinase activity GO:0045859 289 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
chemotaxis GO:0006935 157 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of kinase activity GO:0043549 314 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
mapk cascade GO:0000165 288 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
histone h3 k36 demethylation GO:0070544 5 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
neuroblast proliferation GO:0007405 4 0.016
protein acetylation GO:0006473 116 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
positive regulation of cell death GO:0010942 263 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
response to fungus GO:0009620 4 0.016
cell projection morphogenesis GO:0048858 129 0.016
dna geometric change GO:0032392 32 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
cell cycle g1 s phase transition GO:0044843 80 0.016
Human
blastocyst development GO:0001824 3 0.016
response to biotic stimulus GO:0009607 276 0.016
cell cell signaling GO:0007267 155 0.016
regulation of hormone levels GO:0010817 125 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
negative regulation of organelle organization GO:0010639 126 0.016
growth hormone secretion GO:0030252 4 0.016
histone acetylation GO:0016573 93 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
gene silencing GO:0016458 49 0.015
actin filament based process GO:0030029 224 0.015
regulation of protein ubiquitination GO:0031396 95 0.015
protein processing GO:0016485 226 0.015
negative regulation of developmental process GO:0051093 247 0.015
anatomical structure homeostasis GO:0060249 100 0.015
spermatid differentiation GO:0048515 4 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
negative regulation of protein modification process GO:0031400 200 0.015
biological adhesion GO:0022610 331 0.015
taxis GO:0042330 157 0.015
histone monoubiquitination GO:0010390 20 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
defense response to other organism GO:0098542 129 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
negative regulation of myeloid cell differentiation GO:0045638 42 0.014
negative regulation of chromatin silencing GO:0031936 4 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
protein dna complex assembly GO:0065004 64 0.014
nucleobase containing compound transport GO:0015931 51 0.014
protein targeting GO:0006605 187 0.014
regulation of protein localization GO:0032880 296 0.014
regulation of defense response GO:0031347 154 0.014
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
protein dealkylation GO:0008214 17 0.014
cellular component disassembly GO:0022411 92 0.014
cellular response to oxidative stress GO:0034599 85 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.014
cell growth GO:0016049 160 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
sequestering of metal ion GO:0051238 24 0.014
protein maturation GO:0051604 233 0.013
chordate embryonic development GO:0043009 34 0.013
spermatid development GO:0007286 4 0.013
oocyte development GO:0048599 1 0.013
rna export from nucleus GO:0006405 33 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of protein catabolic process GO:0042176 155 0.013
histone h3 k79 methylation GO:0034729 2 0.013
rho protein signal transduction GO:0007266 26 0.013
regulation of protein processing GO:0070613 150 0.013
negative regulation of protein maturation GO:1903318 142 0.013
cell adhesion GO:0007155 325 0.013
mitotic nuclear division GO:0007067 119 0.013
system process GO:0003008 349 0.013
protein localization to organelle GO:0033365 280 0.013
dephosphorylation GO:0016311 209 0.013
macromolecule methylation GO:0043414 97 0.013
neuron development GO:0048666 113 0.013
chromatin remodeling GO:0006338 55 0.013
Human
protein acylation GO:0043543 138 0.013
histone demethylation GO:0016577 15 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
protein monoubiquitination GO:0006513 39 0.013
skeletal system development GO:0001501 79 0.013
tissue regeneration GO:0042246 3 0.013
regulation of mapk cascade GO:0043408 262 0.013
regulation of leukocyte differentiation GO:1902105 61 0.012
dna replication independent nucleosome organization GO:0034724 27 0.012
cell type specific apoptotic process GO:0097285 125 0.012
regulation of immune response GO:0050776 201 0.012
regulation of chromosome organization GO:0033044 103 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
neuron remodeling GO:0016322 2 0.012
peptidyl lysine acetylation GO:0018394 101 0.012
protein autophosphorylation GO:0046777 123 0.012
nucleosome assembly GO:0006334 50 0.012
histone h2a ubiquitination GO:0033522 17 0.012
single organism membrane organization GO:0044802 268 0.012
regulation of gtpase activity GO:0043087 180 0.012
response to oxygen containing compound GO:1901700 369 0.012
cytokine production GO:0001816 247 0.012
epithelial cell proliferation GO:0050673 128 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
viral life cycle GO:0019058 132 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
endocytosis GO:0006897 159 0.012
protein demethylation GO:0006482 17 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
rna localization GO:0006403 41 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
maintenance of location GO:0051235 112 0.012
embryonic epithelial tube formation GO:0001838 4 0.011
rna transport GO:0050658 39 0.011
histone ubiquitination GO:0016574 31 0.011
cell projection organization GO:0030030 252 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
pattern specification process GO:0007389 43 0.011
Fly
negative regulation of cell cycle process GO:0010948 121 0.011
Human
regulation of cellular protein catabolic process GO:1903362 96 0.011
positive regulation of cytokine production GO:0001819 167 0.011
cell part morphogenesis GO:0032990 137 0.011
circulatory system development GO:0072359 262 0.011
fibroblast apoptotic process GO:0044346 8 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
cellular ion homeostasis GO:0006873 168 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of protein stability GO:0031647 87 0.011
regulation of proteolysis GO:0030162 293 0.011
rna catabolic process GO:0006401 71 0.011
negative regulation of transferase activity GO:0051348 124 0.011
negative regulation of proteolysis GO:0045861 132 0.011
regulation of mrna processing GO:0050684 48 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
Human
regulation of protein transport GO:0051223 213 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
transcription from rna polymerase iii promoter GO:0006383 19 0.011
t cell activation GO:0042110 99 0.011
reproductive structure development GO:0048608 55 0.011
chromosome segregation GO:0007059 114 0.011
tube development GO:0035295 125 0.011
negative regulation of mitotic cell cycle GO:0045930 102 0.011
regulation of chromatin modification GO:1903308 51 0.011
double strand break repair GO:0006302 101 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
Human
positive regulation of gtp catabolic process GO:0033126 166 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
Human
neurotransmitter secretion GO:0007269 4 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
oocyte differentiation GO:0009994 2 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.011
Human
regulation of nervous system development GO:0051960 88 0.011
translation GO:0006412 132 0.010
regulation of protein maturation GO:1903317 150 0.010
protein complex disassembly GO:0043241 52 0.010
aging GO:0007568 66 0.010
reproductive system development GO:0061458 56 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
regulation of dephosphorylation GO:0035303 96 0.010
short term memory GO:0007614 1 0.010
anterior posterior axis specification GO:0009948 2 0.010
Fly
protein polyubiquitination GO:0000209 110 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
viral process GO:0016032 146 0.010
hormone secretion GO:0046879 65 0.010
internal protein amino acid acetylation GO:0006475 101 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
cell development GO:0048468 328 0.010

BRD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.028
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
disease of mental health DOID:150 70 0.019
muscular disease DOID:0080000 114 0.017
muscle tissue disease DOID:66 113 0.017
myopathy DOID:423 104 0.016
developmental disorder of mental health DOID:0060037 29 0.013
central nervous system disease DOID:331 186 0.013
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
eye and adnexa disease DOID:1492 150 0.011