Homo sapiens

36 known processes

DEFA3

defensin, alpha 3, neutrophil-specific

(Aliases: DEF3,HNP3,HP-3,HP3,HNP-3)

DEFA3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.048
innate immune response GO:0045087 178 0.035
small gtpase mediated signal transduction GO:0007264 78 0.035
response to external biotic stimulus GO:0043207 261 0.034
ras protein signal transduction GO:0007265 73 0.032
female gamete generation GO:0007292 2 0.030
immune response GO:0006955 307 0.030
nucleoside catabolic process GO:0009164 408 0.030
multicellular organismal aging GO:0010259 3 0.029
defense response to other organism GO:0098542 129 0.029
cellular amino acid metabolic process GO:0006520 116 0.028
defense response GO:0006952 315 0.027
defense response to bacterium GO:0042742 63 0.027
amine metabolic process GO:0009308 44 0.026
cellular amine metabolic process GO:0044106 41 0.026
oogenesis GO:0048477 2 0.026
response to other organism GO:0051707 261 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
glycosyl compound catabolic process GO:1901658 413 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
response to biotic stimulus GO:0009607 276 0.025
determination of adult lifespan GO:0008340 2 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
rho protein signal transduction GO:0007266 26 0.024
response to bacterium GO:0009617 144 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
cytoplasmic transport GO:0016482 379 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
purine containing compound catabolic process GO:0072523 411 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
nucleotide catabolic process GO:0009166 408 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.021
nucleoside phosphate catabolic process GO:1901292 412 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
cellular ketone metabolic process GO:0042180 80 0.021
locomotory behavior GO:0007626 1 0.021
single organism cellular localization GO:1902580 332 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
organophosphate catabolic process GO:0046434 430 0.019
neuromuscular junction development GO:0007528 3 0.019
mitotic cell cycle GO:0000278 326 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
positive regulation of transport GO:0051050 336 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
positive regulation of cellular amine metabolic process GO:0033240 7 0.018
positive regulation of immune system process GO:0002684 283 0.018
segmentation GO:0035282 4 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
actin filament based process GO:0030029 224 0.018
protein catabolic process GO:0030163 325 0.018
protein localization to organelle GO:0033365 280 0.018
regulation of cellular response to stress GO:0080135 244 0.017
cellular macromolecule catabolic process GO:0044265 380 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
protein processing GO:0016485 226 0.017
lipid metabolic process GO:0006629 381 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
response to oxygen containing compound GO:1901700 369 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
regulation of proteolysis GO:0030162 293 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
regulation of multi organism process GO:0043900 157 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
protein maturation GO:0051604 233 0.016
spermatid differentiation GO:0048515 4 0.016
regulation of intracellular transport GO:0032386 195 0.016
interspecies interaction between organisms GO:0044419 156 0.016
vesicle mediated transport GO:0016192 371 0.016
regulation of transferase activity GO:0051338 355 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
humoral immune response GO:0006959 49 0.016
cellular protein catabolic process GO:0044257 261 0.016
carbohydrate metabolic process GO:0005975 207 0.016
single organism membrane organization GO:0044802 268 0.016
regulation of cell cycle GO:0051726 393 0.016
regulation of kinase activity GO:0043549 314 0.015
nitrogen compound transport GO:0071705 191 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
cellular lipid metabolic process GO:0044255 303 0.015
regulation of protein transport GO:0051223 213 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of peptidase activity GO:0052547 180 0.015
gtp metabolic process GO:0046039 239 0.015
negative regulation of cell death GO:0060548 345 0.015
regulation of protein localization GO:0032880 296 0.015
dephosphorylation GO:0016311 209 0.015
chromatin organization GO:0006325 351 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
response to abiotic stimulus GO:0009628 336 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
chemical homeostasis GO:0048878 306 0.014
memory GO:0007613 3 0.014
cellular component morphogenesis GO:0032989 314 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of mapk cascade GO:0043408 262 0.014
spermatid development GO:0007286 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
intracellular protein transport GO:0006886 270 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
cell morphogenesis GO:0000902 296 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
maintenance of location GO:0051235 112 0.014
membrane organization GO:0061024 292 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
mitotic cell cycle process GO:1903047 286 0.014
oocyte development GO:0048599 1 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
regulation of cell differentiation GO:0045595 393 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
secretion by cell GO:0032940 226 0.013
protein oligomerization GO:0051259 173 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
multi organism cellular process GO:0044764 156 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
viral life cycle GO:0019058 132 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
viral process GO:0016032 146 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
gtp catabolic process GO:0006184 237 0.013
mapk cascade GO:0000165 288 0.013
peripheral nervous system development GO:0007422 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
cation transport GO:0006812 331 0.013
positive regulation of transferase activity GO:0051347 227 0.013
cellular homeostasis GO:0019725 196 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
response to cytokine GO:0034097 232 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
regulation of protein kinase activity GO:0045859 289 0.013
microtubule based process GO:0007017 210 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
protein ubiquitination GO:0016567 314 0.013
cytokine production GO:0001816 247 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.012
chromatin modification GO:0016568 298 0.012
regulation of response to external stimulus GO:0032101 222 0.012
cell projection organization GO:0030030 252 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
regulation of cytokine production GO:0001817 232 0.012
protein targeting GO:0006605 187 0.012
positive regulation of kinase activity GO:0033674 204 0.012
actin cytoskeleton organization GO:0030036 207 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
positive regulation of organelle organization GO:0010638 195 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of protein maturation GO:1903317 150 0.012
regulation of cell cycle process GO:0010564 266 0.012
endomembrane system organization GO:0010256 196 0.012
apoptotic signaling pathway GO:0097190 268 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of defense response GO:0031347 154 0.012
cellular protein complex assembly GO:0043623 188 0.012
negative regulation of cell cycle GO:0045786 193 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
regulation of immune response GO:0050776 201 0.012
covalent chromatin modification GO:0016569 254 0.012
sensory perception of smell GO:0007608 2 0.012
growth GO:0040007 202 0.012
regulation of cellular component movement GO:0051270 334 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
biological adhesion GO:0022610 331 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of cell death GO:0010942 263 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.011
organelle assembly GO:0070925 176 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
regulation of secretion GO:0051046 194 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
positive regulation of protein transport GO:0051222 135 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regeneration GO:0031099 4 0.011
negative regulation of protein maturation GO:1903318 142 0.011
nerve development GO:0021675 4 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of protein complex assembly GO:0043254 147 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
rna processing GO:0006396 255 0.011
blastoderm segmentation GO:0007350 2 0.011
histone modification GO:0016570 251 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
transmembrane transport GO:0055085 399 0.011
protein acylation GO:0043543 138 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
regulation of protein catabolic process GO:0042176 155 0.011
cell growth GO:0016049 160 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
cell cycle phase transition GO:0044770 173 0.011
protein import GO:0017038 130 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.011
response to lipid GO:0033993 206 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
response to fungus GO:0009620 4 0.011
lipid biosynthetic process GO:0008610 177 0.010
hemopoiesis GO:0030097 180 0.010
response to virus GO:0009615 126 0.010
cation homeostasis GO:0055080 189 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
secretion GO:0046903 254 0.010
immune effector process GO:0002252 159 0.010
protein localization to membrane GO:0072657 160 0.010
regulation of protein processing GO:0070613 150 0.010
ion transmembrane transport GO:0034220 338 0.010
cell adhesion GO:0007155 325 0.010
system process GO:0003008 349 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
dna repair GO:0006281 198 0.010
positive regulation of proteolysis GO:0045862 142 0.010
anterior posterior axis specification GO:0009948 2 0.010
hindbrain development GO:0030902 3 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
defense response to gram positive bacterium GO:0050830 29 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
negative regulation of protein processing GO:0010955 142 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
negative regulation of organelle organization GO:0010639 126 0.010
neurological system process GO:0050877 163 0.010
regulation of viral process GO:0050792 103 0.010
cell development GO:0048468 328 0.010

DEFA3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
disease of metabolism DOID:0014667 295 0.019
central nervous system disease DOID:331 186 0.015
eye and adnexa disease DOID:1492 150 0.014
inherited metabolic disorder DOID:655 242 0.014
eye disease DOID:5614 149 0.012
musculoskeletal system disease DOID:17 223 0.012
retinal disease DOID:5679 118 0.011