Homo sapiens

19 known processes

HIGD2A

HIG1 hypoxia inducible domain family, member 2A

(Aliases: MGC2198)

HIGD2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 396 0.417
post embryonic development GO:0009791 2 0.396
generation of precursor metabolites and energy GO:0006091 68 0.276
multicellular organismal aging GO:0010259 3 0.110
negative regulation of apoptotic process GO:0043066 316 0.107
tricarboxylic acid cycle GO:0006099 4 0.105
oxidoreduction coenzyme metabolic process GO:0006733 19 0.099
determination of adult lifespan GO:0008340 2 0.098
aerobic respiration GO:0009060 7 0.095
nucleoside phosphate catabolic process GO:1901292 412 0.095
negative regulation of programmed cell death GO:0043069 321 0.095
cellular respiration GO:0045333 21 0.089
mitochondrial respiratory chain complex assembly GO:0033108 23 0.072
purine ribonucleotide biosynthetic process GO:0009152 79 0.068
apoptotic signaling pathway GO:0097190 268 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.056
nucleoside triphosphate metabolic process GO:0009141 422 0.053
negative regulation of catalytic activity GO:0043086 335 0.053
ribonucleoside monophosphate metabolic process GO:0009161 187 0.052
negative regulation of multicellular organismal process GO:0051241 317 0.050
pyridine nucleotide metabolic process GO:0019362 14 0.050
purine containing compound catabolic process GO:0072523 411 0.049
cofactor metabolic process GO:0051186 87 0.048
carbohydrate derivative biosynthetic process GO:1901137 207 0.048
ribonucleoside triphosphate metabolic process GO:0009199 412 0.048
mitochondrial transport GO:0006839 60 0.047
purine ribonucleoside biosynthetic process GO:0046129 23 0.045
negative regulation of hydrolase activity GO:0051346 182 0.044
energy derivation by oxidation of organic compounds GO:0015980 43 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
coenzyme metabolic process GO:0006732 65 0.042
microtubule cytoskeleton organization GO:0000226 176 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
response to decreased oxygen levels GO:0036293 96 0.039
negative regulation of cell death GO:0060548 345 0.039
nucleotide catabolic process GO:0009166 408 0.037
cellular amino acid metabolic process GO:0006520 116 0.037
system process GO:0003008 349 0.036
microtubule based process GO:0007017 210 0.035
regulation of cellular component biogenesis GO:0044087 281 0.031
ribonucleotide catabolic process GO:0009261 405 0.030
organophosphate catabolic process GO:0046434 430 0.030
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.030
response to oxidative stress GO:0006979 121 0.028
ribose phosphate biosynthetic process GO:0046390 82 0.028
negative regulation of apoptotic signaling pathway GO:2001234 97 0.027
regulation of proteolysis GO:0030162 293 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.025
maintenance of location GO:0051235 112 0.025
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.025
response to axon injury GO:0048678 1 0.025
protein maturation GO:0051604 233 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
Mouse
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.023
neuroblast proliferation GO:0007405 4 0.023
negative regulation of cell proliferation GO:0008285 228 0.023
response to oxygen levels GO:0070482 100 0.023
single organism membrane organization GO:0044802 268 0.023
central nervous system development GO:0007417 123 0.022
head development GO:0060322 108 0.022
response to hormone GO:0009725 175 0.022
response to hypoxia GO:0001666 96 0.021
membrane organization GO:0061024 292 0.021
regulation of transferase activity GO:0051338 355 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
response to abiotic stimulus GO:0009628 336 0.020
atp catabolic process GO:0006200 157 0.020
atp metabolic process GO:0046034 176 0.020
positive regulation of catabolic process GO:0009896 310 0.020
cytoplasmic transport GO:0016482 379 0.019
cellular chemical homeostasis GO:0055082 180 0.019
nucleoside biosynthetic process GO:0009163 26 0.019
cellular response to external stimulus GO:0071496 111 0.019
isocitrate metabolic process GO:0006102 1 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
regulation of protein catabolic process GO:0042176 155 0.018
protein catabolic process GO:0030163 325 0.018
negative regulation of cellular catabolic process GO:0031330 83 0.018
regulation of cell differentiation GO:0045595 393 0.018
endocytosis GO:0006897 159 0.018
negative regulation of oxidoreductase activity GO:0051354 17 0.018
response to lipid GO:0033993 206 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
single organism cellular localization GO:1902580 332 0.017
vesicle mediated transport GO:0016192 371 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
cellular response to nutrient levels GO:0031669 69 0.017
protein localization to membrane GO:0072657 160 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
negative regulation of protein metabolic process GO:0051248 391 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
cellular response to lipid GO:0071396 127 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
response to oxygen containing compound GO:1901700 369 0.016
mitochondrion organization GO:0007005 156 0.016
Mouse
cell growth GO:0016049 160 0.016
negative regulation of growth GO:0045926 97 0.016
negative regulation of catabolic process GO:0009895 104 0.016
guanosine containing compound metabolic process GO:1901068 244 0.015
oogenesis GO:0048477 2 0.015
regeneration GO:0031099 4 0.015
nadph oxidation GO:0070995 3 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
golgi organization GO:0007030 38 0.015
response to cytokine GO:0034097 232 0.015
mitotic cell cycle GO:0000278 326 0.015
cellular response to extracellular stimulus GO:0031668 72 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
regulation of oxidoreductase activity GO:0051341 43 0.015
nicotinamide nucleotide metabolic process GO:0046496 14 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
cation transport GO:0006812 331 0.015
response to biotic stimulus GO:0009607 276 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
establishment of protein localization to mitochondrion GO:0072655 22 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
cation transmembrane transport GO:0098655 238 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
response to organic cyclic compound GO:0014070 204 0.014
citrate metabolic process GO:0006101 2 0.013
response to drug GO:0042493 81 0.013
regulation of peptidase activity GO:0052547 180 0.013
lipid localization GO:0010876 106 0.013
mitotic cell cycle process GO:1903047 286 0.013
mitochondrial calcium ion homeostasis GO:0051560 11 0.013
mitochondrial membrane organization GO:0007006 40 0.013
cellular lipid metabolic process GO:0044255 303 0.013
nadh metabolic process GO:0006734 1 0.013
cellular cation homeostasis GO:0030003 163 0.013
innate immune response GO:0045087 178 0.013
embryo development GO:0009790 123 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
positive regulation of cell death GO:0010942 263 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.012
cellular protein complex assembly GO:0043623 188 0.012
Mouse
negative regulation of transferase activity GO:0051348 124 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
negative regulation of developmental process GO:0051093 247 0.012
cell development GO:0048468 328 0.012
fatty acid derivative metabolic process GO:1901568 35 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
aging GO:0007568 66 0.012
regulation of canonical wnt signaling pathway GO:0060828 88 0.011
mapk cascade GO:0000165 288 0.011
regulation of neurogenesis GO:0050767 82 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
chemical homeostasis GO:0048878 306 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
regulation of protein maturation GO:1903317 150 0.011
amine metabolic process GO:0009308 44 0.011
negative regulation of cell cycle GO:0045786 193 0.011
protein tetramerization GO:0051262 47 0.011
actin filament based process GO:0030029 224 0.011
cellular component morphogenesis GO:0032989 314 0.011
negative regulation of cell growth GO:0030308 83 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
divalent inorganic cation transport GO:0072511 158 0.011
ion homeostasis GO:0050801 230 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of cell motility GO:2000145 299 0.011
epithelial cell differentiation GO:0030855 141 0.011
biological adhesion GO:0022610 331 0.011
response to nitrogen compound GO:1901698 184 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
negative regulation of cell differentiation GO:0045596 171 0.010
regulation of cellular component movement GO:0051270 334 0.010
cellular ion homeostasis GO:0006873 168 0.010
response to bacterium GO:0009617 144 0.010
negative regulation of organelle organization GO:0010639 126 0.010
negative regulation of protein modification process GO:0031400 200 0.010
single organism reproductive process GO:0044702 98 0.010
reproductive structure development GO:0048608 55 0.010

HIGD2A disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
disease of metabolism DOID:0014667 295 0.018
kidney disease DOID:557 36 0.016
urinary system disease DOID:18 40 0.016