Homo sapiens

10 known processes

PTPN12

protein tyrosine phosphatase, non-receptor type 12

(Aliases: PTP-PEST,PTPG1)

PTPN12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell matrix adhesion GO:0001952 42 0.755
cellular response to growth factor stimulus GO:0071363 197 0.726
actin cytoskeleton organization GO:0030036 207 0.715
regulation of kinase activity GO:0043549 314 0.698
vesicle mediated transport GO:0016192 371 0.670
biological adhesion GO:0022610 331 0.662
endochondral bone morphogenesis GO:0060350 3 0.640
positive regulation of map kinase activity GO:0043406 80 0.636
cellular amine metabolic process GO:0044106 41 0.623
actin filament based process GO:0030029 224 0.616
response to growth factor GO:0070848 205 0.606
regulation of cell morphogenesis GO:0022604 153 0.604
cell development GO:0048468 328 0.594
regulation of cell motility GO:2000145 299 0.578
regulation of neuron differentiation GO:0045664 70 0.578
regulation of cell migration GO:0030334 289 0.561
cell matrix adhesion GO:0007160 85 0.538
ras protein signal transduction GO:0007265 73 0.537
positive regulation of cell migration GO:0030335 172 0.534
protein localization to organelle GO:0033365 280 0.532
positive regulation of transferase activity GO:0051347 227 0.519
positive regulation of protein phosphorylation GO:0001934 313 0.516
regulation of protein catabolic process GO:0042176 155 0.514
cell adhesion GO:0007155 325 0.512
digestive tract morphogenesis GO:0048546 56 0.502
tube morphogenesis GO:0035239 95 0.495
cell migration involved in gastrulation GO:0042074 1 0.492
epithelial cell proliferation GO:0050673 128 0.461
regulation of cellular ketone metabolic process GO:0010565 50 0.454
ameboidal type cell migration GO:0001667 135 0.439
regulation of cellular amine metabolic process GO:0033238 11 0.434
single organism cellular localization GO:1902580 332 0.418
enzyme linked receptor protein signaling pathway GO:0007167 303 0.410
positive regulation of developmental process GO:0051094 314 0.408
generation of neurons GO:0048699 152 0.400
single organismal cell cell adhesion GO:0016337 148 0.397
positive regulation of peptidase activity GO:0010952 88 0.389
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.386
regulation of proteolysis GO:0030162 293 0.376
actin filament organization GO:0007015 128 0.376
positive regulation of cell motility GO:2000147 177 0.351
regulation of osteoblast differentiation GO:0045667 38 0.335
positive regulation of epithelial cell migration GO:0010634 55 0.328
positive regulation of locomotion GO:0040017 186 0.325
tube development GO:0035295 125 0.324
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.320
ephrin receptor signaling pathway GO:0048013 15 0.305
osteoblast differentiation GO:0001649 92 0.301
single organism cell adhesion GO:0098602 179 0.300
protein catabolic process GO:0030163 325 0.292
regulation of nervous system development GO:0051960 88 0.289
cell substrate adhesion GO:0031589 132 0.280
positive regulation of proteolysis GO:0045862 142 0.280
protein autophosphorylation GO:0046777 123 0.275
regulation of ossification GO:0030278 58 0.267
regulation of cellular amino acid metabolic process GO:0006521 6 0.260
negative regulation of cell proliferation GO:0008285 228 0.251
regulation of protein kinase activity GO:0045859 289 0.246
amine metabolic process GO:0009308 44 0.241
negative regulation of cell adhesion GO:0007162 64 0.239
regulation of metal ion transport GO:0010959 120 0.226
regulation of growth GO:0040008 165 0.222
heart development GO:0007507 95 0.217
regulation of mapk cascade GO:0043408 262 0.216
negative regulation of protein phosphorylation GO:0001933 140 0.216
regulation of cell adhesion GO:0030155 166 0.213
morphogenesis of a branching epithelium GO:0061138 20 0.211
hard palate development GO:0060022 1 0.208
regulation of transferase activity GO:0051338 355 0.207
post embryonic development GO:0009791 2 0.206
positive regulation of transport GO:0051050 336 0.204
positive regulation of protein kinase activity GO:0045860 190 0.200
epithelial cell migration GO:0010631 119 0.200
neuromuscular junction development GO:0007528 3 0.192
regulation of cellular component movement GO:0051270 334 0.191
cell projection organization GO:0030030 252 0.184
metal ion transport GO:0030001 272 0.184
cellular response to hepatocyte growth factor stimulus GO:0035729 6 0.182
endosomal transport GO:0016197 129 0.181
regulation of cell junction assembly GO:1901888 29 0.180
positive regulation of hydrolase activity GO:0051345 331 0.174
cell growth GO:0016049 160 0.173
negative regulation of cell differentiation GO:0045596 171 0.172
convergent extension involved in gastrulation GO:0060027 1 0.171
regulation of protein localization GO:0032880 296 0.170
signal transduction by phosphorylation GO:0023014 297 0.169
peptidyl tyrosine modification GO:0018212 170 0.168
neurogenesis GO:0022008 169 0.167
regulation of cellular response to growth factor stimulus GO:0090287 76 0.167
ion transmembrane transport GO:0034220 338 0.165
tissue migration GO:0090130 119 0.164
ossification GO:0001503 121 0.161
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.161
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.158
positive regulation of cytoplasmic transport GO:1903651 82 0.158
regulation of neuron projection development GO:0010975 57 0.156
blood vessel morphogenesis GO:0048514 162 0.155
regulation of vesicle mediated transport GO:0060627 130 0.151
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.151
positive regulation of cell proliferation GO:0008284 301 0.148
positive regulation of mapk cascade GO:0043410 190 0.147
endochondral ossification GO:0001958 1 0.146
skeletal system development GO:0001501 79 0.145
growth GO:0040007 202 0.143
Rat
regulation of cellular component size GO:0032535 82 0.141
response to cytokine GO:0034097 232 0.135
neuron development GO:0048666 113 0.134
positive regulation of cell adhesion GO:0045785 84 0.132
monocyte activation GO:0042117 3 0.131
muscle cell migration GO:0014812 19 0.126
endocytosis GO:0006897 159 0.126
protein kinase b signaling GO:0043491 69 0.125
activation of protein kinase activity GO:0032147 90 0.125
convergent extension GO:0060026 1 0.125
cellular macromolecular complex assembly GO:0034622 324 0.124
cellular amino acid metabolic process GO:0006520 116 0.121
epithelium migration GO:0090132 119 0.120
neuron projection development GO:0031175 106 0.120
tor signaling GO:0031929 39 0.117
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.117
Human
regulation of locomotion GO:0040012 329 0.116
hematopoietic or lymphoid organ development GO:0048534 186 0.116
regulation of endothelial cell migration GO:0010594 67 0.115
phosphatidylinositol mediated signaling GO:0048015 55 0.115
purine nucleoside catabolic process GO:0006152 398 0.113
regulation of cell growth GO:0001558 135 0.112
digestive system development GO:0055123 75 0.112
circulatory system development GO:0072359 262 0.112
negative regulation of catalytic activity GO:0043086 335 0.111
regulation of nucleoside metabolic process GO:0009118 209 0.107
nucleoside triphosphate catabolic process GO:0009143 394 0.106
erk1 and erk2 cascade GO:0070371 104 0.106
molting cycle GO:0042303 28 0.106
regulation of cell projection organization GO:0031344 107 0.105
digestive tract development GO:0048565 75 0.105
cellular component morphogenesis GO:0032989 314 0.104
regulation of erk1 and erk2 cascade GO:0070372 99 0.104
cellular ketone metabolic process GO:0042180 80 0.102
positive regulation of endothelial cell migration GO:0010595 39 0.100
regulation of nucleocytoplasmic transport GO:0046822 98 0.099
regulation of protein transport GO:0051223 213 0.098
cell junction organization GO:0034330 79 0.098
peptidyl serine modification GO:0018209 106 0.098
positive regulation of nucleoside metabolic process GO:0045979 186 0.096
regulation of cell substrate adhesion GO:0010810 68 0.096
intracellular protein transport GO:0006886 270 0.095
endothelial cell proliferation GO:0001935 65 0.095
protein targeting GO:0006605 187 0.095
response to mechanical stimulus GO:0009612 51 0.094
oogenesis GO:0048477 2 0.092
neuron differentiation GO:0030182 138 0.092
positive regulation of neuron differentiation GO:0045666 40 0.090
positive regulation of immune system process GO:0002684 283 0.089
Human
negative regulation of cell death GO:0060548 345 0.089
modification dependent protein catabolic process GO:0019941 209 0.088
mitochondrion organization GO:0007005 156 0.088
activation of janus kinase activity GO:0042976 7 0.087
positive regulation of immune response GO:0050778 159 0.086
Human
regulation of response to external stimulus GO:0032101 222 0.086
negative regulation of cellular amine metabolic process GO:0033239 3 0.085
response to inorganic substance GO:0010035 127 0.085
regulation of neurogenesis GO:0050767 82 0.083
cell activation GO:0001775 213 0.083
Human
positive regulation of ossification GO:0045778 32 0.083
regulation of protein secretion GO:0050708 86 0.082
negative regulation of cellular protein metabolic process GO:0032269 353 0.081
angiogenesis GO:0001525 147 0.081
ribonucleoside triphosphate metabolic process GO:0009199 412 0.081
rna processing GO:0006396 255 0.081
positive regulation of cellular component organization GO:0051130 376 0.080
monovalent inorganic cation transport GO:0015672 128 0.080
negative regulation of apoptotic process GO:0043066 316 0.080
regulation of map kinase activity GO:0043405 108 0.079
cellular response to hormone stimulus GO:0032870 125 0.077
positive regulation of cell projection organization GO:0031346 64 0.077
nuclear transport GO:0051169 179 0.077
circulatory system process GO:0003013 113 0.076
regulation of epithelial cell migration GO:0010632 93 0.075
ribonucleoside catabolic process GO:0042454 406 0.075
mitotic cell cycle GO:0000278 326 0.074
positive regulation of intracellular transport GO:0032388 104 0.074
establishment of organelle localization GO:0051656 59 0.073
immune system development GO:0002520 195 0.073
regulation of cellular component biogenesis GO:0044087 281 0.072
myoblast fusion GO:0007520 1 0.072
positive regulation of vasodilation GO:0045909 4 0.072
positive regulation of cell growth GO:0030307 48 0.071
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.071
gtp catabolic process GO:0006184 237 0.070
positive regulation of cellular component movement GO:0051272 181 0.070
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.069
negative regulation of transferase activity GO:0051348 124 0.068
muscle cell differentiation GO:0042692 63 0.068
hemopoiesis GO:0030097 180 0.068
regulation of peptidase activity GO:0052547 180 0.067
cellular macromolecule catabolic process GO:0044265 380 0.067
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.067
anatomical structure formation involved in morphogenesis GO:0048646 284 0.066
response to transforming growth factor beta GO:0071559 94 0.065
striated muscle contraction GO:0006941 52 0.065
regulation of growth rate GO:0040009 1 0.065
cytokine mediated signaling pathway GO:0019221 109 0.065
cellular response to endogenous stimulus GO:0071495 336 0.065
endodermal cell differentiation GO:0035987 31 0.065
regulation of nucleotide catabolic process GO:0030811 205 0.064
positive regulation of neuron projection development GO:0010976 34 0.064
adherens junction organization GO:0034332 36 0.064
nervous system development GO:0007399 293 0.063
endothelial cell migration GO:0043542 86 0.063
positive regulation of organelle organization GO:0010638 195 0.063
protein modification by small protein conjugation GO:0032446 342 0.062
regulation of intracellular transport GO:0032386 195 0.062
protein localization to endoplasmic reticulum GO:0070972 19 0.061
wnt signaling pathway GO:0016055 156 0.061
regulation of sodium ion transmembrane transport GO:1902305 23 0.061
nucleoside catabolic process GO:0009164 408 0.061
positive regulation of wnt signaling pathway GO:0030177 54 0.060
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.060
morphogenesis of a branching structure GO:0001763 21 0.059
lymphocyte activation GO:0046649 133 0.059
Human
potassium ion transport GO:0006813 62 0.059
negative regulation of programmed cell death GO:0043069 321 0.059
negative regulation of axonogenesis GO:0050771 4 0.058
platelet activation GO:0030168 44 0.058
regulation of cell development GO:0060284 161 0.058
regulation of actin cytoskeleton organization GO:0032956 116 0.057
vasodilation GO:0042311 4 0.057
ncrna metabolic process GO:0034660 108 0.057
nucleocytoplasmic transport GO:0006913 176 0.057
regulation of cytoplasmic transport GO:1903649 149 0.057
organonitrogen compound biosynthetic process GO:1901566 200 0.057
positive regulation of cell matrix adhesion GO:0001954 23 0.056
protein localization to membrane GO:0072657 160 0.056
immune response regulating signaling pathway GO:0002764 97 0.055
Human
negative regulation of cellular component organization GO:0051129 235 0.055
cellular protein complex assembly GO:0043623 188 0.054
regulation of canonical wnt signaling pathway GO:0060828 88 0.054
gastrulation GO:0007369 51 0.053
positive regulation of protein kinase b signaling GO:0051897 42 0.053
cellular protein catabolic process GO:0044257 261 0.053
female gamete generation GO:0007292 2 0.052
positive regulation of protein transport GO:0051222 135 0.052
immune response activating signal transduction GO:0002757 90 0.052
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.051
response to drug GO:0042493 81 0.051
blood vessel development GO:0001568 172 0.051
positive regulation of cellular amine metabolic process GO:0033240 7 0.050
regulation of transporter activity GO:0032409 82 0.050
positive regulation of phosphorylation GO:0042327 394 0.050
embryo development GO:0009790 123 0.049
protein ubiquitination GO:0016567 314 0.049
positive regulation of cell development GO:0010720 92 0.048
response to oxidative stress GO:0006979 121 0.047
muscle structure development GO:0061061 98 0.047
positive regulation of catabolic process GO:0009896 310 0.047
response to tumor necrosis factor GO:0034612 76 0.047
response to nitrogen compound GO:1901698 184 0.047
negative regulation of transport GO:0051051 176 0.046
oocyte development GO:0048599 1 0.046
regulation of endocytosis GO:0030100 72 0.046
organelle assembly GO:0070925 176 0.046
modification dependent macromolecule catabolic process GO:0043632 212 0.045
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.045
oocyte differentiation GO:0009994 2 0.045
membrane organization GO:0061024 292 0.045
positive regulation of cellular component biogenesis GO:0044089 158 0.045
cell morphogenesis GO:0000902 296 0.045
neurotrophin trk receptor signaling pathway GO:0048011 4 0.044
nucleoside triphosphate metabolic process GO:0009141 422 0.044
epithelium development GO:0060429 227 0.044
mitotic cell cycle phase transition GO:0044772 162 0.044
regulation of actin filament based process GO:0032970 141 0.043
peptide metabolic process GO:0006518 51 0.043
cardiovascular system development GO:0072358 262 0.043
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.043
chondrocyte proliferation GO:0035988 4 0.043
epithelial cell differentiation GO:0030855 141 0.043
regulation of protein import into nucleus GO:0042306 78 0.043
response to organonitrogen compound GO:0010243 156 0.043
guanosine containing compound catabolic process GO:1901069 239 0.043
membrane protein proteolysis GO:0033619 38 0.042
mapk cascade GO:0000165 288 0.042
establishment of protein localization to endoplasmic reticulum membrane GO:0097051 3 0.041
cellular response to nutrient levels GO:0031669 69 0.041
cell chemotaxis GO:0060326 112 0.041
g1 s transition of mitotic cell cycle GO:0000082 78 0.040
positive regulation of jak stat cascade GO:0046427 35 0.040
system process GO:0003008 349 0.040
regulation of cellular response to stress GO:0080135 244 0.040
positive regulation of neurogenesis GO:0050769 49 0.040
regulation of ion transport GO:0043269 189 0.040
regulation of actin filament polymerization GO:0030833 50 0.040
positive regulation of osteoblast differentiation GO:0045669 23 0.039
positive regulation of intracellular protein transport GO:0090316 76 0.039
response to hormone GO:0009725 175 0.039
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.039
organic hydroxy compound metabolic process GO:1901615 147 0.039
syncytium formation by plasma membrane fusion GO:0000768 2 0.038
cell cell junction organization GO:0045216 69 0.038
regulation of smooth muscle cell migration GO:0014910 15 0.038
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.038
Human
cellular response to oxygen containing compound GO:1901701 276 0.038
regulation of cytoskeleton organization GO:0051493 177 0.038
proteasomal protein catabolic process GO:0010498 176 0.038
cell adhesion mediated by integrin GO:0033627 27 0.038
organophosphate biosynthetic process GO:0090407 163 0.038
glial cell migration GO:0008347 4 0.038
positive regulation of synaptic transmission GO:0050806 4 0.038
leukocyte differentiation GO:0002521 98 0.037
cellular response to organonitrogen compound GO:0071417 124 0.037
hepatocyte growth factor receptor signaling pathway GO:0048012 8 0.037
regulation of vasodilation GO:0042312 4 0.036
myeloid leukocyte activation GO:0002274 34 0.035
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.035
negative regulation of protein modification process GO:0031400 200 0.035
positive regulation of cell substrate adhesion GO:0010811 37 0.035
negative regulation of cell substrate adhesion GO:0010812 24 0.035
retinal ganglion cell axon guidance GO:0031290 2 0.035
regulation of intracellular protein transport GO:0033157 123 0.035
regulation of wnt signaling pathway GO:0030111 123 0.035
nucleoside phosphate catabolic process GO:1901292 412 0.035
response to hypoxia GO:0001666 96 0.035
rho protein signal transduction GO:0007266 26 0.035
regulation of blood circulation GO:1903522 59 0.035
membrane protein ectodomain proteolysis GO:0006509 33 0.034
purine containing compound catabolic process GO:0072523 411 0.034
embryonic morphogenesis GO:0048598 85 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.034
single organism nuclear import GO:1902593 104 0.034
heart process GO:0003015 62 0.034
regulation of protein serine threonine kinase activity GO:0071900 179 0.034
cell type specific apoptotic process GO:0097285 125 0.033
epithelial cell development GO:0002064 34 0.033
nitrogen compound transport GO:0071705 191 0.033
regulation of transmembrane transport GO:0034762 139 0.033
organophosphate catabolic process GO:0046434 430 0.033
cell cycle g1 s phase transition GO:0044843 80 0.032
establishment of protein localization to organelle GO:0072594 172 0.032
negative regulation of cell migration GO:0030336 102 0.032
wound healing GO:0042060 115 0.032
Rat
multicellular organismal aging GO:0010259 3 0.032
maintenance of cell polarity GO:0030011 2 0.032
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.032
response to abiotic stimulus GO:0009628 336 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
regulation of endopeptidase activity GO:0052548 170 0.031
leukocyte migration GO:0050900 107 0.031
positive regulation of cell differentiation GO:0045597 211 0.030
transmembrane transport GO:0055085 399 0.030
plasma membrane organization GO:0007009 115 0.030
organelle fission GO:0048285 149 0.030
pattern specification process GO:0007389 43 0.030
branching morphogenesis of an epithelial tube GO:0048754 19 0.030
autophagy GO:0006914 88 0.030
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.030
glycosyl compound catabolic process GO:1901658 413 0.030
sodium ion transmembrane transport GO:0035725 59 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.029
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.029
regulation of protein targeting GO:1903533 91 0.029
canonical wnt signaling pathway GO:0060070 116 0.029
morphogenesis of an epithelium GO:0002009 60 0.029
neural crest cell migration GO:0001755 2 0.029
adherens junction assembly GO:0034333 34 0.029
receptor mediated endocytosis GO:0006898 84 0.029
regulation of stress activated mapk cascade GO:0032872 84 0.028
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.028
myeloid cell differentiation GO:0030099 117 0.028
regulation of cellular protein catabolic process GO:1903362 96 0.028
organ morphogenesis GO:0009887 147 0.028
regeneration GO:0031099 4 0.028
Rat
regulation of ion transmembrane transporter activity GO:0032412 72 0.028
regulation of immune response GO:0050776 201 0.028
Human
regulation of transmembrane transporter activity GO:0022898 74 0.028
cellular response to nitrogen compound GO:1901699 144 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
positive regulation of growth GO:0045927 58 0.027
salivary gland morphogenesis GO:0007435 4 0.027
development of primary sexual characteristics GO:0045137 35 0.027
protein localization to nucleus GO:0034504 136 0.027
developmental process involved in reproduction GO:0003006 66 0.027
cell substrate junction assembly GO:0007044 35 0.027
establishment or maintenance of cell polarity GO:0007163 31 0.027
inositol lipid mediated signaling GO:0048017 55 0.027
unidimensional cell growth GO:0009826 1 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.026
actin filament capping GO:0051693 4 0.026
smooth muscle cell migration GO:0014909 18 0.026
negative regulation of locomotion GO:0040013 118 0.026
positive regulation of kinase activity GO:0033674 204 0.026
retina vasculature development in camera type eye GO:0061298 3 0.026
negative regulation of developmental process GO:0051093 247 0.026
mitotic cell cycle process GO:1903047 286 0.026
positive regulation of dendrite morphogenesis GO:0050775 3 0.026
epithelial tube morphogenesis GO:0060562 38 0.026
inorganic ion transmembrane transport GO:0098660 231 0.025
determination of adult lifespan GO:0008340 2 0.025
nuclear import GO:0051170 106 0.025
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.025
negative regulation of growth GO:0045926 97 0.025
gastrulation with mouth forming second GO:0001702 1 0.025
homotypic cell cell adhesion GO:0034109 47 0.025
ncrna processing GO:0034470 83 0.025
actin cytoskeleton reorganization GO:0031532 37 0.025
blastoderm segmentation GO:0007350 2 0.025
endodermal cell fate specification GO:0001714 4 0.025
regulation of sodium ion transport GO:0002028 24 0.025
organelle localization GO:0051640 84 0.025
positive regulation of exocytosis GO:0045921 35 0.024
regulation of cell differentiation GO:0045595 393 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.024
peptidyl tyrosine phosphorylation GO:0018108 170 0.024
regulation of receptor mediated endocytosis GO:0048259 32 0.024
synaptic vesicle endocytosis GO:0048488 2 0.024
negative regulation of endopeptidase activity GO:0010951 84 0.024
regulation of secretion by cell GO:1903530 177 0.024
protein maturation GO:0051604 233 0.023
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
skeletal system morphogenesis GO:0048705 24 0.023
protein targeting to nucleus GO:0044744 104 0.023
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.023
dephosphorylation GO:0016311 209 0.023
Human Mouse Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
sex differentiation GO:0007548 45 0.023
lens morphogenesis in camera type eye GO:0002089 2 0.023
leukocyte chemotaxis GO:0030595 76 0.023
neuron death GO:0070997 65 0.022
negative regulation of peptidase activity GO:0010466 91 0.022
response to metal ion GO:0010038 84 0.022
endocrine process GO:0050886 25 0.022
positive regulation of behavior GO:0048520 60 0.022
regulation of protein kinase b signaling GO:0051896 61 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
peptidyl tyrosine dephosphorylation GO:0035335 36 0.022
Human Rat
maintenance of location in cell GO:0051651 62 0.022
regulation of cell substrate junction assembly GO:0090109 20 0.022
regulation of ion transmembrane transport GO:0034765 132 0.022
jnk cascade GO:0007254 80 0.021
positive regulation of leukocyte chemotaxis GO:0002690 38 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.021
heart contraction GO:0060047 62 0.021
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 2 0.021
central nervous system neuron axonogenesis GO:0021955 3 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.021
erbb signaling pathway GO:0038127 44 0.021
retrograde transport endosome to golgi GO:0042147 45 0.021
positive regulation of jnk cascade GO:0046330 52 0.020
regulation of protein complex assembly GO:0043254 147 0.020
maintenance of location GO:0051235 112 0.020
actin filament polymerization GO:0030041 45 0.020
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.020
microtubule based process GO:0007017 210 0.020
vasculature development GO:0001944 181 0.020
blood coagulation GO:0007596 76 0.020
dna replication GO:0006260 116 0.020
mesenchymal cell differentiation GO:0048762 52 0.020
nerve development GO:0021675 4 0.020
cytoplasmic transport GO:0016482 379 0.020
regulation of dna metabolic process GO:0051052 153 0.020
peptidyl serine phosphorylation GO:0018105 101 0.019
regulation of heart growth GO:0060420 4 0.019
mononuclear cell proliferation GO:0032943 71 0.019
Human
negative regulation of protein maturation GO:1903318 142 0.019
regulation of homeostatic process GO:0032844 121 0.019
regulation of anatomical structure size GO:0090066 101 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
ribonucleoprotein complex biogenesis GO:0022613 116 0.019
regulation of cell cycle GO:0051726 393 0.019
positive regulation of cytokine production GO:0001819 167 0.019
response to radiation GO:0009314 151 0.019
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.019
bone development GO:0060348 26 0.019
neural crest cell development GO:0014032 3 0.019
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 6 0.018
positive regulation of cytoskeleton organization GO:0051495 83 0.018
peptide transport GO:0015833 74 0.018
spermatid differentiation GO:0048515 4 0.018
cellular cation homeostasis GO:0030003 163 0.018
mitotic nuclear division GO:0007067 119 0.018
regulation of actin polymerization or depolymerization GO:0008064 56 0.018
lipid metabolic process GO:0006629 381 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.018
negative regulation of protein kinase activity GO:0006469 98 0.018
glycoprotein biosynthetic process GO:0009101 91 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.018
gonad development GO:0008406 34 0.018

PTPN12 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.160
Human
inherited metabolic disorder DOID:655 242 0.160
metal metabolism disorder DOID:896 19 0.160
disease of cellular proliferation DOID:14566 174 0.089
cancer DOID:162 167 0.063
organ system cancer DOID:0050686 164 0.063
musculoskeletal system disease DOID:17 223 0.031
Human
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019