|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.999
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.998
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.998
|
Mouse |
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.998
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.998
|
Mouse |
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.993
|
|
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
0.992
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.988
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.986
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.983
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.974
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.972
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.967
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.957
|
Mouse Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.947
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.932
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.928
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.928
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.922
|
Mouse Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.918
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.912
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.908
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.885
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.882
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.881
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.878
|
Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.860
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.852
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.851
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.851
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.847
|
Mouse |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.847
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.832
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.825
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.810
|
Mouse |
|
|
negative regulation of meiotic cell cycle
|
GO:0051447 |
2 |
0.796
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.795
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.791
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.785
|
Mouse |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.784
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.778
|
Mouse |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.768
|
Mouse |
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.766
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.757
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.712
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.698
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.697
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.684
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.683
|
Mouse |
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.671
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.669
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.657
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.645
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.645
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.640
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.623
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.618
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.616
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.605
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.599
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.589
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.572
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.568
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.565
|
Mouse |
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.564
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.554
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.554
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.550
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.548
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.547
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.546
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.532
|
Mouse |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.525
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.522
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.503
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.493
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.490
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.471
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.469
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.468
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.456
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.456
|
Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.455
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.438
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
6 |
0.433
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.426
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.416
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.414
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.395
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.386
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.380
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.379
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.375
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.361
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.358
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.355
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.337
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.330
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.329
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.328
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.327
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.323
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.313
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.311
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.304
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.303
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.300
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.292
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.290
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
11 |
0.282
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.278
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.276
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.271
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.266
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.263
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.262
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.258
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.258
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.257
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.252
|
|
|
|
centromere complex assembly
|
GO:0034508 |
10 |
0.250
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.246
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.246
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.241
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.235
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.228
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.224
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.215
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.207
|
|
|
|
regulation of g0 to g1 transition
|
GO:0070316 |
2 |
0.207
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.203
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.200
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.197
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.196
|
Mouse |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.195
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.194
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.193
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.190
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.186
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
65 |
0.186
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.179
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.177
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.174
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.174
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.173
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.169
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.166
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.166
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.166
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.162
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.161
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.159
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.155
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.154
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.150
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.148
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.143
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.142
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.139
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.139
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.137
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.135
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.134
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.134
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.133
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.133
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.130
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.129
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.129
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.128
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.128
|
|
|
|
triglyceride catabolic process
|
GO:0019433 |
10 |
0.127
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.127
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.127
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.127
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.127
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.126
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.126
|
|
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
0.124
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.124
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.123
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.117
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.116
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.113
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.112
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.111
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.110
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.107
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.104
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.104
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.104
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.103
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.103
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.102
|
|
|
|
protein localization to kinetochore
|
GO:0034501 |
10 |
0.101
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.100
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.099
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.097
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.096
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.096
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.095
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.094
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.094
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.091
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.091
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.091
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.089
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.088
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.086
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.085
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.084
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.084
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.083
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.083
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.083
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.082
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.081
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.081
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.079
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.078
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
18 |
0.077
|
|
|
|
7 methylguanosine mrna capping
|
GO:0006370 |
7 |
0.076
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.076
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.074
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.074
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.074
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.074
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.074
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.074
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.073
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.072
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.070
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.069
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.069
|
|
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
6 |
0.068
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.068
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.067
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.066
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.066
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.066
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.064
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.064
|
|
|
|
negative regulation of sister chromatid segregation
|
GO:0033046 |
17 |
0.064
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.063
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.063
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.062
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.062
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.062
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.062
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.061
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.061
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.061
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.060
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.060
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.060
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.059
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.059
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.059
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.059
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.058
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.058
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.058
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.057
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.056
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.056
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.055
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.055
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.054
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.054
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.054
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.054
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.054
|
Mouse |
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.053
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.053
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.052
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.052
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.052
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.052
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.052
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.052
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.051
|
|
|
|
luteolysis
|
GO:0001554 |
3 |
0.050
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
11 |
0.050
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.050
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.050
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.049
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.049
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.049
|
|
|
|
negative regulation of metaphase anaphase transition of cell cycle
|
GO:1902100 |
17 |
0.049
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.049
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.048
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.048
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.047
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.046
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.046
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.046
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.046
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.046
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.046
|
|
|
|
system process
|
GO:0003008 |
349 |
0.046
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.045
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.045
|
|
|
|
cell maturation
|
GO:0048469 |
11 |
0.045
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.044
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.044
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.044
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.044
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.044
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.044
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.043
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.043
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.043
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.042
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
23 |
0.042
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.042
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.041
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.041
|
|
|
|
centrosome duplication
|
GO:0051298 |
28 |
0.040
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.038
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
13 |
0.038
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.038
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.038
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.037
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.037
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.037
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.036
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.035
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.035
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.035
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.035
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.035
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.034
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.034
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.034
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.033
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.033
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.033
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.033
|
|
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.033
|
|
|
|
protein neddylation
|
GO:0045116 |
7 |
0.033
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.032
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.032
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.032
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.032
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.032
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.032
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.032
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.031
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.031
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.031
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.031
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.030
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.030
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.029
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.029
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.028
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.028
|
|
|
|
regulation of mitotic spindle organization
|
GO:0060236 |
6 |
0.028
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.028
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.028
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.028
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.027
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.027
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.027
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.026
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.026
|
|
|
|
regulation of centrosome duplication
|
GO:0010824 |
14 |
0.026
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.026
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.026
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.026
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.025
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.025
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.025
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.024
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.024
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.024
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.023
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.023
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.023
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.023
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.023
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.023
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.023
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.023
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.023
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.022
|
|
|
|
negative regulation of mitotic sister chromatid separation
|
GO:2000816 |
17 |
0.022
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.022
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.022
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.022
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.022
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.022
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.022
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.021
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.021
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.021
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.021
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.021
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.021
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.021
|
|
|
|
regulation of chromatin binding
|
GO:0035561 |
3 |
0.020
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.020
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.020
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.020
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.020
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.020
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.020
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.020
|
|
|
|
positive regulation of heart growth
|
GO:0060421 |
2 |
0.019
|
|
|
|
dna endoreduplication
|
GO:0042023 |
5 |
0.019
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.019
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.019
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.019
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.019
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.019
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.019
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.019
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.019
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.018
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.018
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.018
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.018
|
|
|
|
positive regulation of meiosis
|
GO:0045836 |
2 |
0.018
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.018
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.018
|
|
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.018
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.018
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.018
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.018
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.017
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.017
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.017
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.017
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.017
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.017
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.017
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.017
|
Fly |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.017
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.017
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.017
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.017
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.016
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.016
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.016
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.016
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.016
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.016
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.016
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.016
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.016
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.015
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.015
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.015
|
|
|
|
aging
|
GO:0007568 |
66 |
0.015
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.015
|
|
|
|
positive regulation of attachment of spindle microtubules to kinetochore
|
GO:0051987 |
2 |
0.015
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.015
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.015
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.015
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.014
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.014
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.014
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.014
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.014
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.014
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.013
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.013
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.013
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.013
|
|
|
|
mitotic metaphase plate congression
|
GO:0007080 |
14 |
0.013
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.013
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.013
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.013
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.012
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.012
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.012
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.012
|
|
|
|
protein autoprocessing
|
GO:0016540 |
4 |
0.012
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
15 |
0.012
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.012
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.012
|
|
|
|
positive regulation of nuclear cell cycle dna replication
|
GO:0010571 |
4 |
0.012
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.012
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.012
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.012
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.012
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.011
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.011
|
|
|
|
nuclear dna replication
|
GO:0033260 |
6 |
0.011
|
|
