Homo sapiens

17 known processes

S1PR1

sphingosine-1-phosphate receptor 1

(Aliases: D1S3362,EDG1,EDG-1,S1P1,FLJ58121,CHEDG1,ECGF1)

S1PR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cyclic nucleotide metabolic process GO:0009187 82 0.234
biological adhesion GO:0022610 331 0.189
Mouse
amine metabolic process GO:0009308 44 0.186
anatomical structure formation involved in morphogenesis GO:0048646 284 0.170
Zebrafish Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.164
Rat
cellular ketone metabolic process GO:0042180 80 0.161
cellular amine metabolic process GO:0044106 41 0.159
regulation of locomotion GO:0040012 329 0.149
Zebrafish Rat
regulation of cellular ketone metabolic process GO:0010565 50 0.145
vasculature development GO:0001944 181 0.141
Zebrafish Mouse
circulatory system development GO:0072359 262 0.138
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.136
negative regulation of developmental process GO:0051093 247 0.129
Human
positive regulation of phosphorylation GO:0042327 394 0.128
gtp metabolic process GO:0046039 239 0.127
Rat
purine containing compound catabolic process GO:0072523 411 0.121
Rat
nucleotide catabolic process GO:0009166 408 0.121
Rat
cardiovascular system development GO:0072358 262 0.120
Zebrafish Mouse
blood vessel morphogenesis GO:0048514 162 0.119
Mouse
cell adhesion GO:0007155 325 0.119
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.119
Rat
regulation of cellular amine metabolic process GO:0033238 11 0.118
negative regulation of protein metabolic process GO:0051248 391 0.115
nervous system development GO:0007399 293 0.115
Mouse Rat
cell development GO:0048468 328 0.114
Human
gtp catabolic process GO:0006184 237 0.109
Rat
organophosphate catabolic process GO:0046434 430 0.108
Rat
cellular amino acid metabolic process GO:0006520 116 0.108
regulation of cell migration GO:0030334 289 0.106
Zebrafish Rat
purine nucleotide catabolic process GO:0006195 405 0.105
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.105
Rat
blood vessel development GO:0001568 172 0.105
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.105
ribonucleoside catabolic process GO:0042454 406 0.103
Rat
glycosyl compound catabolic process GO:1901658 413 0.103
Rat
angiogenesis GO:0001525 147 0.103
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.102
Rat
regulation of cellular component movement GO:0051270 334 0.101
Zebrafish Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.099
Rat
ribonucleoside triphosphate metabolic process GO:0009199 412 0.098
Rat
regulation of cell differentiation GO:0045595 393 0.097
Human
post embryonic development GO:0009791 2 0.096
regulation of cell motility GO:2000145 299 0.095
Zebrafish Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.095
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.094
Rat
ribonucleotide catabolic process GO:0009261 405 0.093
Rat
nucleoside triphosphate metabolic process GO:0009141 422 0.091
Rat
purine ribonucleoside catabolic process GO:0046130 398 0.091
Rat
regulation of epithelial cell migration GO:0010632 93 0.090
guanosine containing compound metabolic process GO:1901068 244 0.090
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.089
immune response GO:0006955 307 0.084
organonitrogen compound biosynthetic process GO:1901566 200 0.081
cyclic purine nucleotide metabolic process GO:0052652 60 0.081
g protein coupled receptor signaling pathway GO:0007186 207 0.080
nucleoside triphosphate catabolic process GO:0009143 394 0.080
Rat
defense response GO:0006952 315 0.079
positive regulation of cellular amine metabolic process GO:0033240 7 0.078
nucleoside catabolic process GO:0009164 408 0.078
Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.078
purine nucleoside catabolic process GO:0006152 398 0.077
Rat
guanosine containing compound catabolic process GO:1901069 239 0.077
Rat
single organism cell adhesion GO:0098602 179 0.076
negative regulation of cellular protein metabolic process GO:0032269 353 0.074
regulation of vasculature development GO:1901342 97 0.073
regulation of mapk cascade GO:0043408 262 0.073
epithelial cell migration GO:0010631 119 0.072
regulation of angiogenesis GO:0045765 92 0.072
endothelial cell migration GO:0043542 86 0.070
epithelium migration GO:0090132 119 0.070
epithelial cell differentiation GO:0030855 141 0.070
Human Rat
regulation of endothelial cell migration GO:0010594 67 0.069
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.069
Rat
negative regulation of apoptotic process GO:0043066 316 0.069
chemical homeostasis GO:0048878 306 0.069
Rat
ras protein signal transduction GO:0007265 73 0.069
negative regulation of cell death GO:0060548 345 0.067
negative regulation of phosphate metabolic process GO:0045936 267 0.067
positive regulation of hydrolase activity GO:0051345 331 0.066
Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.065
tissue migration GO:0090130 119 0.063
Zebrafish
small gtpase mediated signal transduction GO:0007264 78 0.063
response to abiotic stimulus GO:0009628 336 0.062
cellular component morphogenesis GO:0032989 314 0.061
response to oxygen containing compound GO:1901700 369 0.060
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.060
system process GO:0003008 349 0.059
Rat
negative regulation of catalytic activity GO:0043086 335 0.059
regulation of purine nucleotide metabolic process GO:1900542 264 0.058
Rat
negative regulation of programmed cell death GO:0043069 321 0.058
regulation of response to external stimulus GO:0032101 222 0.058
Rat
hemopoiesis GO:0030097 180 0.058
regulation of protein transport GO:0051223 213 0.057
nucleoside phosphate biosynthetic process GO:1901293 109 0.057
single organismal cell cell adhesion GO:0016337 148 0.057
immune system development GO:0002520 195 0.057
mapk cascade GO:0000165 288 0.056
positive regulation of cell proliferation GO:0008284 301 0.056
Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 230 0.056
Rat
organophosphate biosynthetic process GO:0090407 163 0.056
cation transport GO:0006812 331 0.055
signal transduction by phosphorylation GO:0023014 297 0.054
locomotory behavior GO:0007626 1 0.054
camp metabolic process GO:0046058 61 0.054
regulation of transferase activity GO:0051338 355 0.054
negative regulation of cell proliferation GO:0008285 228 0.054
purine ribonucleotide biosynthetic process GO:0009152 79 0.053
lipid metabolic process GO:0006629 381 0.053
cell fate determination GO:0001709 3 0.053
enzyme linked receptor protein signaling pathway GO:0007167 303 0.052
positive regulation of immune system process GO:0002684 283 0.052
cytokine production GO:0001816 247 0.052
cyclic nucleotide biosynthetic process GO:0009190 61 0.051
positive regulation of cell motility GO:2000147 177 0.051
Zebrafish Rat
camp biosynthetic process GO:0006171 47 0.050
response to organic cyclic compound GO:0014070 204 0.050
response to cytokine GO:0034097 232 0.050
segmentation GO:0035282 4 0.049
regulation of cytokine production GO:0001817 232 0.049
regulation of body fluid levels GO:0050878 99 0.048
negative regulation of phosphorus metabolic process GO:0010563 267 0.048
positive regulation of cellular component movement GO:0051272 181 0.048
Zebrafish Rat
response to growth factor GO:0070848 205 0.048
purine containing compound biosynthetic process GO:0072522 88 0.048
regulation of cell cycle GO:0051726 393 0.047
regulation of protein kinase activity GO:0045859 289 0.046
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.046
single organism cellular localization GO:1902580 332 0.046
nucleotide biosynthetic process GO:0009165 109 0.045
ion homeostasis GO:0050801 230 0.045
Rat
positive regulation of cytokine production GO:0001819 167 0.045
motor neuron axon guidance GO:0008045 2 0.044
regulation of nucleotide metabolic process GO:0006140 269 0.044
Rat
female gamete generation GO:0007292 2 0.044
cellular response to oxygen containing compound GO:1901701 276 0.044
regulation of protein localization GO:0032880 296 0.044
positive regulation of protein phosphorylation GO:0001934 313 0.044
ameboidal type cell migration GO:0001667 135 0.044
Zebrafish
cell morphogenesis GO:0000902 296 0.044
response to wounding GO:0009611 168 0.043
cellular homeostasis GO:0019725 196 0.043
Rat
cytoplasmic transport GO:0016482 379 0.043
epithelium development GO:0060429 227 0.042
Human Rat
regulation of gtp catabolic process GO:0033124 180 0.042
Rat
cellular response to endogenous stimulus GO:0071495 336 0.042
taxis GO:0042330 157 0.042
Mouse Rat
cell activation GO:0001775 213 0.041
cellular ion homeostasis GO:0006873 168 0.041
Rat
regulation of establishment of protein localization GO:0070201 242 0.041
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.041
Rat
positive regulation of mapk cascade GO:0043410 190 0.041
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.041
ribonucleotide biosynthetic process GO:0009260 81 0.041
determination of adult lifespan GO:0008340 2 0.041
hematopoietic or lymphoid organ development GO:0048534 186 0.041
hemostasis GO:0007599 76 0.040
epithelial cell proliferation GO:0050673 128 0.040
regulation of proteolysis GO:0030162 293 0.040
response to other organism GO:0051707 261 0.040
neurogenesis GO:0022008 169 0.040
Rat
neuroblast proliferation GO:0007405 4 0.040
positive regulation of apoptotic process GO:0043065 246 0.040
positive regulation of transport GO:0051050 336 0.039
cellular lipid metabolic process GO:0044255 303 0.039
positive regulation of cellular catabolic process GO:0031331 284 0.039
Rat
regulation of kinase activity GO:0043549 314 0.039
cation homeostasis GO:0055080 189 0.038
Rat
response to biotic stimulus GO:0009607 276 0.038
regulation of nucleoside metabolic process GO:0009118 209 0.038
Rat
multicellular organismal aging GO:0010259 3 0.038
protein maturation GO:0051604 233 0.038
coagulation GO:0050817 78 0.038
positive regulation of cell migration GO:0030335 172 0.038
Zebrafish Rat
positive regulation of cellular component organization GO:0051130 376 0.038
cell substrate adhesion GO:0031589 132 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
metal ion transport GO:0030001 272 0.037
negative regulation of protein modification process GO:0031400 200 0.037
purine nucleotide biosynthetic process GO:0006164 84 0.037
reactive nitrogen species metabolic process GO:2001057 3 0.037
negative regulation of vasculature development GO:1901343 43 0.036
positive regulation of developmental process GO:0051094 314 0.036
Human
actin filament based process GO:0030029 224 0.036
Mouse Rat
regulation of cellular component biogenesis GO:0044087 281 0.036
Rat
oogenesis GO:0048477 2 0.036
ribose phosphate biosynthetic process GO:0046390 82 0.035
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.035
mitotic cell cycle GO:0000278 326 0.035
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
Rat
tube development GO:0035295 125 0.035
Zebrafish
vesicle mediated transport GO:0016192 371 0.035
regulation of cell development GO:0060284 161 0.034
Human
response to nitrogen compound GO:1901698 184 0.034
regulation of immune response GO:0050776 201 0.034
growth GO:0040007 202 0.033
Mouse
negative regulation of cellular amine metabolic process GO:0033239 3 0.033
cellular response to nitrogen compound GO:1901699 144 0.033
regulation of cell adhesion GO:0030155 166 0.033
Mouse
cell projection organization GO:0030030 252 0.033
Mouse
anterior posterior axis specification GO:0009948 2 0.033
generation of neurons GO:0048699 152 0.033
Rat
secretion by cell GO:0032940 226 0.033
negative regulation of cell differentiation GO:0045596 171 0.033
Human
negative regulation of angiogenesis GO:0016525 39 0.032
cellular cation homeostasis GO:0030003 163 0.032
Rat
cellular divalent inorganic cation homeostasis GO:0072503 128 0.032
Rat
regulation of cell cycle process GO:0010564 266 0.032
regulation of response to wounding GO:1903034 101 0.031
blood coagulation GO:0007596 76 0.031
mitotic cell cycle process GO:1903047 286 0.031
metal ion homeostasis GO:0055065 169 0.031
Rat
blastoderm segmentation GO:0007350 2 0.031
peptidyl tyrosine modification GO:0018212 170 0.031
protein processing GO:0016485 226 0.031
positive regulation of catabolic process GO:0009896 310 0.031
Rat
response to hormone GO:0009725 175 0.031
hindbrain development GO:0030902 3 0.030
regulation of epithelial cell proliferation GO:0050678 113 0.030
rho protein signal transduction GO:0007266 26 0.030
cellular response to growth factor stimulus GO:0071363 197 0.030
apoptotic signaling pathway GO:0097190 268 0.030
leukocyte migration GO:0050900 107 0.030
Mouse
actin cytoskeleton organization GO:0030036 207 0.030
Mouse Rat
regeneration GO:0031099 4 0.030
positive regulation of programmed cell death GO:0043068 249 0.030
protein catabolic process GO:0030163 325 0.030
regulation of ras protein signal transduction GO:0046578 155 0.029
Rat
ion transmembrane transport GO:0034220 338 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.029
Rat
positive regulation of gtp catabolic process GO:0033126 166 0.029
Rat
response to external biotic stimulus GO:0043207 261 0.029
protein ubiquitination GO:0016567 314 0.029
cellular response to cytokine stimulus GO:0071345 181 0.029
protein localization to organelle GO:0033365 280 0.029
neuron differentiation GO:0030182 138 0.029
Rat
memory GO:0007613 3 0.029
microtubule cytoskeleton organization GO:0000226 176 0.029
negative regulation of blood vessel morphogenesis GO:2000181 41 0.029
intracellular protein transport GO:0006886 270 0.028
leukocyte activation GO:0045321 164 0.028
central nervous system development GO:0007417 123 0.028
Mouse
response to lipid GO:0033993 206 0.028
regulation of cellular response to stress GO:0080135 244 0.028
innate immune response GO:0045087 178 0.028
regulation of gtpase activity GO:0043087 180 0.028
Rat
immune effector process GO:0002252 159 0.028
cytosolic calcium ion homeostasis GO:0051480 89 0.027
Rat
regulation of nucleotide catabolic process GO:0030811 205 0.027
Rat
regulation of camp metabolic process GO:0030814 52 0.027
microtubule based process GO:0007017 210 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
negative regulation of protein phosphorylation GO:0001933 140 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
reactive oxygen species metabolic process GO:0072593 75 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
morphogenesis of embryonic epithelium GO:0016331 4 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
inorganic ion transmembrane transport GO:0098660 231 0.026
tissue morphogenesis GO:0048729 96 0.026
Zebrafish Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
positive regulation of ras gtpase activity GO:0032320 117 0.026
Rat
positive regulation of cell death GO:0010942 263 0.026
regulation of protein processing GO:0070613 150 0.026
cell junction organization GO:0034330 79 0.026
wound healing GO:0042060 115 0.026
regulation of peptidase activity GO:0052547 180 0.026
wnt signaling pathway GO:0016055 156 0.026
maintenance of location GO:0051235 112 0.026
positive regulation of protein kinase activity GO:0045860 190 0.025
regulation of ion transport GO:0043269 189 0.025
regulation of endopeptidase activity GO:0052548 170 0.025
transmembrane transport GO:0055085 399 0.025
positive regulation of locomotion GO:0040017 186 0.025
Zebrafish Rat
cell division GO:0051301 168 0.025
regulation of small gtpase mediated signal transduction GO:0051056 156 0.025
Rat
organ morphogenesis GO:0009887 147 0.025
Mouse
divalent inorganic cation transport GO:0072511 158 0.025
oxidation reduction process GO:0055114 396 0.025
regulation of intracellular transport GO:0032386 195 0.025
protein modification by small protein conjugation GO:0032446 342 0.025
receptor internalization GO:0031623 43 0.025
regulation of defense response GO:0031347 154 0.025
negative regulation of cell migration GO:0030336 102 0.025
neurological system process GO:0050877 163 0.024
Rat
cell cell signaling GO:0007267 155 0.024
negative regulation of epithelial cell proliferation GO:0050680 48 0.024
positive regulation of cell differentiation GO:0045597 211 0.024
Human
regulation of ras gtpase activity GO:0032318 128 0.024
Rat
cardiac muscle cell contraction GO:0086003 4 0.024
cellular chemical homeostasis GO:0055082 180 0.024
Rat
regulation of secretion GO:0051046 194 0.024
positive regulation of kinase activity GO:0033674 204 0.024
regulation of nucleotide biosynthetic process GO:0030808 50 0.024
negative regulation of protein processing GO:0010955 142 0.024
muscle system process GO:0003012 81 0.024
dephosphorylation GO:0016311 209 0.024
response to organonitrogen compound GO:0010243 156 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.024
Rat
negative regulation of cell motility GO:2000146 104 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.024
mating GO:0007618 1 0.024
regulation of cell activation GO:0050865 125 0.024
blood circulation GO:0008015 113 0.024
calcium ion transport GO:0006816 147 0.023
secretion GO:0046903 254 0.023
membrane organization GO:0061024 292 0.023
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.023
response to oxygen levels GO:0070482 100 0.023
divalent inorganic cation homeostasis GO:0072507 136 0.023
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.023
cell chemotaxis GO:0060326 112 0.023
positive regulation of protein transport GO:0051222 135 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
long term memory GO:0007616 2 0.023
negative regulation of cell fate specification GO:0009996 3 0.023
reactive oxygen species biosynthetic process GO:1903409 4 0.023
rhythmic behavior GO:0007622 2 0.023
cellular metal ion homeostasis GO:0006875 146 0.023
Rat
single organism membrane organization GO:0044802 268 0.023
anion transport GO:0006820 161 0.023
limbic system development GO:0021761 3 0.023
lipid biosynthetic process GO:0008610 177 0.022
myeloid cell differentiation GO:0030099 117 0.022
somatic stem cell division GO:0048103 1 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
neuromuscular junction development GO:0007528 3 0.022
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.022
response to hypoxia GO:0001666 96 0.022
regulation of protein maturation GO:1903317 150 0.022
tube morphogenesis GO:0035239 95 0.022
Zebrafish
negative regulation of locomotion GO:0040013 118 0.022
regulation of secretion by cell GO:1903530 177 0.022
chemotaxis GO:0006935 157 0.022
Mouse Rat
calcium ion homeostasis GO:0055074 122 0.022
Rat
regulation of homeostatic process GO:0032844 121 0.022
Mouse
negative regulation of proteolysis GO:0045861 132 0.022
tripartite regional subdivision GO:0007351 2 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
positive regulation of endothelial cell migration GO:0010595 39 0.022
protein targeting GO:0006605 187 0.022
inorganic cation transmembrane transport GO:0098662 194 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
regulation of growth GO:0040008 165 0.021
canonical wnt signaling pathway GO:0060070 116 0.021
cellular calcium ion homeostasis GO:0006874 117 0.021
Rat
negative regulation of cell fate commitment GO:0010454 3 0.021
divalent metal ion transport GO:0070838 152 0.021
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.021
positive regulation of transferase activity GO:0051347 227 0.021
positive regulation of immune response GO:0050778 159 0.021
negative regulation of cell cycle GO:0045786 193 0.021
negative regulation of transport GO:0051051 176 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
lymphocyte activation GO:0046649 133 0.021
nuclear transport GO:0051169 179 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
nitrogen compound transport GO:0071705 191 0.020
organ formation GO:0048645 3 0.020
negative regulation of protein maturation GO:1903318 142 0.020
glycerolipid metabolic process GO:0046486 107 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
Rat
brain development GO:0007420 97 0.020
Mouse
cell growth GO:0016049 160 0.020
stress activated protein kinase signaling cascade GO:0031098 94 0.020
receptor metabolic process GO:0043112 81 0.020
cellular response to organonitrogen compound GO:0071417 124 0.020
negative regulation of peptidase activity GO:0010466 91 0.020
somatic stem cell maintenance GO:0035019 4 0.020
circadian behavior GO:0048512 2 0.020
response to oxidative stress GO:0006979 121 0.020
blood vessel endothelial cell migration GO:0043534 42 0.020
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.020
regulation of cytoplasmic transport GO:1903649 149 0.019
endocytosis GO:0006897 159 0.019
head development GO:0060322 108 0.019
Mouse
peripheral nervous system development GO:0007422 2 0.019
regulation of synaptic plasticity GO:0048167 3 0.019
cell type specific apoptotic process GO:0097285 125 0.019
negative regulation of epithelial cell migration GO:0010633 38 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
Rat
muscle structure development GO:0061061 98 0.019
Mouse
regulation of apoptotic signaling pathway GO:2001233 175 0.019
cell cell junction organization GO:0045216 69 0.019
angiogenesis involved in wound healing GO:0060055 4 0.019
adult locomotory behavior GO:0008344 1 0.019
glycoprotein biosynthetic process GO:0009101 91 0.019
oocyte development GO:0048599 1 0.019
regulation of intracellular protein transport GO:0033157 123 0.019
pituitary gland development GO:0021983 2 0.019
salivary gland morphogenesis GO:0007435 4 0.019
embryo development GO:0009790 123 0.019
Zebrafish
photoreceptor cell differentiation GO:0046530 2 0.019
cytokine mediated signaling pathway GO:0019221 109 0.019
associative learning GO:0008306 1 0.019
sex determination GO:0007530 3 0.019
negative regulation of cell adhesion GO:0007162 64 0.018
cellular protein catabolic process GO:0044257 261 0.018
endothelial cell proliferation GO:0001935 65 0.018
neuron development GO:0048666 113 0.018
response to decreased oxygen levels GO:0036293 96 0.018
spermatid differentiation GO:0048515 4 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
nuclear import GO:0051170 106 0.018
oocyte differentiation GO:0009994 2 0.018
compound eye development GO:0048749 1 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
peptidyl lysine modification GO:0018205 144 0.018
neuron projection development GO:0031175 106 0.018
cation transmembrane transport GO:0098655 238 0.018
endomembrane system organization GO:0010256 196 0.018
regulation of membrane potential GO:0042391 95 0.018
regulation of protein secretion GO:0050708 86 0.017
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.017
fatty acid metabolic process GO:0006631 115 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
cell matrix adhesion GO:0007160 85 0.017
action potential GO:0001508 34 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
regulation of system process GO:0044057 101 0.017
regulation of multi organism process GO:0043900 157 0.017
stem cell division GO:0017145 2 0.017
syncytium formation by plasma membrane fusion GO:0000768 2 0.017
muscle contraction GO:0006936 73 0.017
inner ear morphogenesis GO:0042472 4 0.017
metencephalon development GO:0022037 2 0.017
lipid localization GO:0010876 106 0.017
regulation of erk1 and erk2 cascade GO:0070372 99 0.017
regulation of cell growth GO:0001558 135 0.017
cell part morphogenesis GO:0032990 137 0.017
leukocyte chemotaxis GO:0030595 76 0.017
positive regulation of secretion GO:0051047 116 0.017
cerebellum development GO:0021549 2 0.017
cell projection morphogenesis GO:0048858 129 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.017
Human Mouse Rat
positive regulation of epithelial cell migration GO:0010634 55 0.017
erk1 and erk2 cascade GO:0070371 104 0.017
protein localization to membrane GO:0072657 160 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
negative regulation of immune system process GO:0002683 136 0.016
second messenger mediated signaling GO:0019932 78 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.016
Rat
spermatid development GO:0007286 4 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
cardiac cell fate determination GO:0060913 3 0.016
regulation of endothelial cell proliferation GO:0001936 56 0.016
regulation of leukocyte activation GO:0002694 115 0.016
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.016
patterning of blood vessels GO:0001569 2 0.016
t cell differentiation in thymus GO:0033077 4 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
Rat
regulation of cell division GO:0051302 116 0.016
cellular response to lipid GO:0071396 127 0.016
lipid transport GO:0006869 90 0.016
actin filament based movement GO:0030048 17 0.016
regulation of behavior GO:0050795 82 0.016
Rat
cellular response to oxidative stress GO:0034599 85 0.016
regulation of cellular response to growth factor stimulus GO:0090287 76 0.016
regulation of cell cell adhesion GO:0022407 57 0.016
regulation of protein stability GO:0031647 87 0.016
cell cycle phase transition GO:0044770 173 0.016
negative regulation of endopeptidase activity GO:0010951 84 0.016
regulation of protein catabolic process GO:0042176 155 0.016
negative regulation of growth GO:0045926 97 0.016
asymmetric stem cell division GO:0098722 1 0.016
response to inorganic substance GO:0010035 127 0.016
glycoprotein metabolic process GO:0009100 110 0.015
positive regulation of cell adhesion GO:0045785 84 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
negative regulation of cellular component movement GO:0051271 106 0.015
sequestering of calcium ion GO:0051208 17 0.015
negative regulation of kinase activity GO:0033673 106 0.015
jnk cascade GO:0007254 80 0.015
regulation of stress activated mapk cascade GO:0032872 84 0.015
chromatin organization GO:0006325 351 0.015

S1PR1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.027
sensory system disease DOID:0050155 203 0.026
nervous system disease DOID:863 431 0.026
cancer DOID:162 167 0.025
organ system cancer DOID:0050686 164 0.025
eye and adnexa disease DOID:1492 150 0.023
disease of metabolism DOID:0014667 295 0.021
immune system disease DOID:2914 155 0.021
central nervous system disease DOID:331 186 0.018
cardiovascular system disease DOID:1287 106 0.017
eye disease DOID:5614 149 0.016
musculoskeletal system disease DOID:17 223 0.016