Homo sapiens

9 known processes

FANCA

Fanconi anemia, complementation group A

(Aliases: FACA,FA1,FA-H,FA,FAH,MGC75158,FAA,FANCH)

FANCA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 198 1.000
cellular response to dna damage stimulus GO:0006974 379 0.990
recombinational repair GO:0000725 50 0.983
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.965
double strand break repair via homologous recombination GO:0000724 50 0.868
dna dependent dna replication GO:0006261 44 0.656
regeneration GO:0031099 4 0.606
g2 dna damage checkpoint GO:0031572 26 0.445
mitochondrion organization GO:0007005 156 0.412
chromatin modification GO:0016568 298 0.397
oocyte development GO:0048599 1 0.378
post embryonic development GO:0009791 2 0.370
meiotic chromosome separation GO:0051307 3 0.366
double strand break repair GO:0006302 101 0.354
oogenesis GO:0048477 2 0.324
negative regulation of mitotic cell cycle GO:0045930 102 0.292
dna damage checkpoint GO:0000077 68 0.271
meiosis i GO:0007127 4 0.268
replication fork processing GO:0031297 13 0.253
chromatin organization GO:0006325 351 0.241
dna replication GO:0006260 116 0.235
oocyte differentiation GO:0009994 2 0.234
tissue regeneration GO:0042246 3 0.208
telomere maintenance GO:0000723 32 0.198
dna conformation change GO:0071103 113 0.190
chromatin assembly or disassembly GO:0006333 78 0.188
microtubule based process GO:0007017 210 0.182
mitotic dna damage checkpoint GO:0044773 28 0.172
chemical homeostasis GO:0048878 306 0.151
chromatin remodeling GO:0006338 55 0.147
atp metabolic process GO:0046034 176 0.141
neuronal ion channel clustering GO:0045161 2 0.103
oocyte maturation GO:0001556 1 0.099
negative regulation of cell cycle GO:0045786 193 0.096
organelle fission GO:0048285 149 0.096
Mouse
dna recombination GO:0006310 77 0.093
cell cycle checkpoint GO:0000075 117 0.093
receptor mediated endocytosis GO:0006898 84 0.088
protein complex disassembly GO:0043241 52 0.085
positive regulation of developmental process GO:0051094 314 0.084
vesicle mediated transport GO:0016192 371 0.080
response to oxygen containing compound GO:1901700 369 0.078
atp catabolic process GO:0006200 157 0.077
covalent chromatin modification GO:0016569 254 0.075
dna double strand break processing GO:0000729 10 0.074
mitotic cell cycle process GO:1903047 286 0.066
double strand break repair via single strand annealing GO:0045002 4 0.064
t cell activation GO:0042110 99 0.064
purine containing compound catabolic process GO:0072523 411 0.063
endocytosis GO:0006897 159 0.063
growth GO:0040007 202 0.063
purine ribonucleoside catabolic process GO:0046130 398 0.063
cellular macromolecule catabolic process GO:0044265 380 0.062
anterior posterior axis specification GO:0009948 2 0.062
cell cycle phase transition GO:0044770 173 0.061
purine nucleoside catabolic process GO:0006152 398 0.060
neuronal stem cell division GO:0036445 1 0.059
determination of adult lifespan GO:0008340 2 0.058
dna integrity checkpoint GO:0031570 71 0.058
meiotic chromosome segregation GO:0045132 4 0.056
cellular amino acid metabolic process GO:0006520 116 0.055
nuclear division GO:0000280 128 0.054
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.054
regulation of mitotic cell cycle phase transition GO:1901990 118 0.053
response to organic cyclic compound GO:0014070 204 0.052
ribonucleotide catabolic process GO:0009261 405 0.052
male meiosis GO:0007140 1 0.052
Mouse
ion homeostasis GO:0050801 230 0.051
mitotic cell cycle phase transition GO:0044772 162 0.050
negative regulation of cell cycle process GO:0010948 121 0.050
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.048
cell projection morphogenesis GO:0048858 129 0.048
regulation of cell cycle GO:0051726 393 0.048
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
chromosome separation GO:0051304 23 0.047
nucleoside phosphate catabolic process GO:1901292 412 0.047
female gamete generation GO:0007292 2 0.047
tissue homeostasis GO:0001894 63 0.046
cellular component disassembly GO:0022411 92 0.046
neuron development GO:0048666 113 0.043
regulation of cell cycle phase transition GO:1901987 126 0.043
chromatin disassembly GO:0031498 13 0.042
response to reactive oxygen species GO:0000302 61 0.042
negative regulation of programmed cell death GO:0043069 321 0.041
nucleotide catabolic process GO:0009166 408 0.040
cell division GO:0051301 168 0.040
multicellular organismal aging GO:0010259 3 0.040
response to drug GO:0042493 81 0.040
reproductive process GO:0022414 106 0.039
Mouse
anatomical structure homeostasis GO:0060249 100 0.039
cellular response to endogenous stimulus GO:0071495 336 0.038
cellular ketone metabolic process GO:0042180 80 0.038
neuron projection development GO:0031175 106 0.038
response to inorganic substance GO:0010035 127 0.037
chromosome segregation GO:0007059 114 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
epithelium development GO:0060429 227 0.036
actin filament based process GO:0030029 224 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
positive regulation of cellular amine metabolic process GO:0033240 7 0.036
reciprocal meiotic recombination GO:0007131 4 0.036
mitotic sister chromatid segregation GO:0000070 53 0.035
leukocyte activation GO:0045321 164 0.034
chromatin mediated maintenance of transcription GO:0048096 2 0.033
nucleoside monophosphate metabolic process GO:0009123 191 0.033
macromolecular complex disassembly GO:0032984 60 0.031
positive regulation of organelle organization GO:0010638 195 0.031
regulation of cellular response to stress GO:0080135 244 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
negative regulation of cell cycle phase transition GO:1901988 89 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
purine nucleoside monophosphate catabolic process GO:0009128 158 0.030
response to nitrogen compound GO:1901698 184 0.029
protein dna complex subunit organization GO:0071824 80 0.029
regulation of gene expression epigenetic GO:0040029 73 0.029
dna geometric change GO:0032392 32 0.029
organophosphate catabolic process GO:0046434 430 0.029
nucleoside catabolic process GO:0009164 408 0.028
ras protein signal transduction GO:0007265 73 0.028
positive regulation of triglyceride metabolic process GO:0090208 9 0.028
response to organonitrogen compound GO:0010243 156 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
positive regulation of leukocyte activation GO:0002696 80 0.027
mitotic cell cycle GO:0000278 326 0.027
protein modification by small protein conjugation GO:0032446 342 0.026
embryo development GO:0009790 123 0.026
immune response GO:0006955 307 0.026
single organism reproductive process GO:0044702 98 0.025
Mouse
cellular response to nitrogen compound GO:1901699 144 0.025
regulation of protein kinase activity GO:0045859 289 0.025
t cell differentiation GO:0030217 29 0.024
mitotic nuclear division GO:0007067 119 0.024
protein ubiquitination GO:0016567 314 0.024
protein oligomerization GO:0051259 173 0.024
nucleotide excision repair GO:0006289 31 0.023
dephosphorylation GO:0016311 209 0.023
mitotic dna integrity checkpoint GO:0044774 30 0.023
regulation of transferase activity GO:0051338 355 0.023
organ morphogenesis GO:0009887 147 0.023
mitotic dna replication checkpoint GO:0033314 2 0.023
neuroendocrine cell differentiation GO:0061101 2 0.022
cell development GO:0048468 328 0.022
protein maturation GO:0051604 233 0.022
hemopoiesis GO:0030097 180 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
regulation of growth GO:0040008 165 0.021
regulation of meiotic cell cycle GO:0051445 4 0.021
protein catabolic process GO:0030163 325 0.021
blastocyst development GO:0001824 3 0.021
nucleosome organization GO:0034728 66 0.021
mitotic g2 m transition checkpoint GO:0044818 9 0.021
cellular chemical homeostasis GO:0055082 180 0.021
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
neuromuscular junction development GO:0007528 3 0.020
reproduction GO:0000003 63 0.020
Mouse
cell activation GO:0001775 213 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
cellular protein catabolic process GO:0044257 261 0.018
amine metabolic process GO:0009308 44 0.018
positive regulation of protein kinase activity GO:0045860 190 0.017
intracellular protein transport GO:0006886 270 0.017
rna processing GO:0006396 255 0.017
negative regulation of organelle organization GO:0010639 126 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
reproductive system development GO:0061458 56 0.017
Mouse
circulatory system development GO:0072359 262 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.017
positive regulation of lymphocyte activation GO:0051251 73 0.017
protein dna complex disassembly GO:0032986 12 0.017
regulation of multi organism process GO:0043900 157 0.017
membrane organization GO:0061024 292 0.017
regulation of cell cycle process GO:0010564 266 0.017
positive regulation of cell proliferation GO:0008284 301 0.016
mitotic cell cycle checkpoint GO:0007093 68 0.016
muscle tissue development GO:0060537 62 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
response to wounding GO:0009611 168 0.016
response to hydrogen peroxide GO:0042542 40 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
positive regulation of immune system process GO:0002684 283 0.016
gland development GO:0048732 48 0.016
striated muscle cell differentiation GO:0051146 43 0.016
cell type specific apoptotic process GO:0097285 125 0.016
maintenance of location GO:0051235 112 0.016
nervous system development GO:0007399 293 0.016
carbohydrate metabolic process GO:0005975 207 0.016
regulation of proteolysis GO:0030162 293 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
double strand break repair via nonhomologous end joining GO:0006303 10 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
long chain fatty acid biosynthetic process GO:0042759 4 0.015
response to fungus GO:0009620 4 0.015
peptidyl threonine phosphorylation GO:0018107 41 0.015
positive regulation of cell activation GO:0050867 81 0.015
positive regulation of immune response GO:0050778 159 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of hormone secretion GO:0046883 57 0.015
organelle assembly GO:0070925 176 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
nuclear import GO:0051170 106 0.015
regulation of lymphocyte activation GO:0051249 103 0.015
establishment of protein localization to organelle GO:0072594 172 0.014
cytoplasmic transport GO:0016482 379 0.014
lymphocyte activation GO:0046649 133 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
single organism membrane organization GO:0044802 268 0.014
negative regulation of cell death GO:0060548 345 0.014
muscle cell differentiation GO:0042692 63 0.014
calcium ion homeostasis GO:0055074 122 0.014
t cell differentiation in thymus GO:0033077 4 0.014
regulation of cell activation GO:0050865 125 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
response to hypoxia GO:0001666 96 0.013
resolution of meiotic recombination intermediates GO:0000712 3 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.013
multicellular organismal homeostasis GO:0048871 67 0.013
regulation of protein catabolic process GO:0042176 155 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
negative regulation of protein processing GO:0010955 142 0.013
response to abiotic stimulus GO:0009628 336 0.013
segmentation GO:0035282 4 0.013
regulation of dna replication GO:0006275 68 0.013
single organism cellular localization GO:1902580 332 0.013
hindbrain development GO:0030902 3 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
protein targeting GO:0006605 187 0.013
regulation of dna repair GO:0006282 47 0.013
cell cycle g1 s phase transition GO:0044843 80 0.012
mitotic sister chromatid separation GO:0051306 18 0.012
cation homeostasis GO:0055080 189 0.012
spermatid differentiation GO:0048515 4 0.012
activation of protein kinase activity GO:0032147 90 0.012
response to metal ion GO:0010038 84 0.012
gene conversion GO:0035822 1 0.012
neural tube closure GO:0001843 3 0.012
regulation of protein localization GO:0032880 296 0.012
myosin filament organization GO:0031033 2 0.012
viral genome replication GO:0019079 50 0.012
regulation of protein stability GO:0031647 87 0.012
positive regulation of kinase activity GO:0033674 204 0.012
regulation of cell development GO:0060284 161 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.011
signal release GO:0023061 70 0.011
dna biosynthetic process GO:0071897 40 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
regulation of dna dependent dna replication GO:0090329 19 0.011
actin cytoskeleton organization GO:0030036 207 0.011
dna duplex unwinding GO:0032508 30 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
digestive system development GO:0055123 75 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
negative regulation of transport GO:0051051 176 0.011
chromatin remodeling at centromere GO:0031055 2 0.011
positive regulation of t cell activation GO:0050870 54 0.011
glycogen catabolic process GO:0005980 4 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
regulation of centrosome cycle GO:0046605 15 0.011
regulation of mitotic sister chromatid segregation GO:0033047 27 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
regulation of phosphatase activity GO:0010921 81 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of t cell activation GO:0050863 77 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
cell cycle g2 m phase transition GO:0044839 43 0.011
maintenance of dna repeat elements GO:0043570 4 0.011
peptidyl lysine modification GO:0018205 144 0.011
cellular cation homeostasis GO:0030003 163 0.010
translesion synthesis GO:0019985 8 0.010
carbohydrate catabolic process GO:0016052 36 0.010
cell morphogenesis GO:0000902 296 0.010
regulation of viral process GO:0050792 103 0.010
positive regulation of dna metabolic process GO:0051054 73 0.010
response to ionizing radiation GO:0010212 65 0.010
reciprocal dna recombination GO:0035825 4 0.010
regulation of protein processing GO:0070613 150 0.010
secretion GO:0046903 254 0.010
muscle structure development GO:0061061 98 0.010
metencephalon development GO:0022037 2 0.010

FANCA disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 1.000
bone marrow disease DOID:4961 31 1.000
hematopoietic system disease DOID:74 100 1.000
aplastic anemia DOID:12449 30 1.000
anemia DOID:2355 55 1.000
congenital hypoplastic anemia DOID:1342 26 1.000
fanconi s anemia DOID:13636 16 1.000
cancer DOID:162 167 0.815
disease of cellular proliferation DOID:14566 174 0.815
organ system cancer DOID:0050686 164 0.370
breast cancer DOID:1612 21 0.183
thoracic cancer DOID:5093 21 0.183
epilepsy syndrome DOID:1826 41 0.042
central nervous system disease DOID:331 186 0.042
brain disease DOID:936 73 0.042
electroclinical syndrome DOID:0050701 32 0.042
neonatal period electroclinical syndrome DOID:0050702 19 0.042
nervous system disease DOID:863 431 0.042
idiopathic generalized epilepsy DOID:1827 21 0.041
musculoskeletal system disease DOID:17 223 0.035
connective tissue disease DOID:65 109 0.035
ohtahara syndrome DOID:0050709 17 0.019
gastrointestinal system cancer DOID:3119 52 0.013
reproductive organ cancer DOID:193 23 0.012
bone disease DOID:0080001 88 0.012