Homo sapiens

63 known processes

FANCM

Fanconi anemia, complementation group M

(Aliases: MGC176453,KIAA1596,FAAP250)

FANCM biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
replication fork processing GO:0031297 13 0.990
meiotic chromosome segregation GO:0045132 4 0.755
meiotic chromosome separation GO:0051307 3 0.715
cellular response to dna damage stimulus GO:0006974 379 0.597
dna dependent dna replication GO:0006261 44 0.554
dna repair GO:0006281 198 0.435
dna recombination GO:0006310 77 0.417
dna replication GO:0006260 116 0.327
organelle fission GO:0048285 149 0.308
meiosis i GO:0007127 4 0.253
chromosome separation GO:0051304 23 0.232
chromosome segregation GO:0007059 114 0.196
double strand break repair via homologous recombination GO:0000724 50 0.166
oocyte development GO:0048599 1 0.161
protein monoubiquitination GO:0006513 39 0.143
resolution of meiotic recombination intermediates GO:0000712 3 0.141
reciprocal dna recombination GO:0035825 4 0.140
protein ubiquitination GO:0016567 314 0.140
reciprocal meiotic recombination GO:0007131 4 0.136
purine nucleoside monophosphate catabolic process GO:0009128 158 0.132
nuclear division GO:0000280 128 0.130
mitochondrion organization GO:0007005 156 0.108
regeneration GO:0031099 4 0.106
protein modification by small protein conjugation GO:0032446 342 0.100
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.085
purine ribonucleotide catabolic process GO:0009154 404 0.084
oocyte differentiation GO:0009994 2 0.060
atp catabolic process GO:0006200 157 0.045
female gamete generation GO:0007292 2 0.043
purine nucleotide catabolic process GO:0006195 405 0.038
purine containing compound catabolic process GO:0072523 411 0.037
negative regulation of cell death GO:0060548 345 0.035
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
negative regulation of programmed cell death GO:0043069 321 0.033
ribonucleoside triphosphate metabolic process GO:0009199 412 0.033
ribonucleoside catabolic process GO:0042454 406 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
regulation of transferase activity GO:0051338 355 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.029
negative regulation of cell cycle GO:0045786 193 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
chemical homeostasis GO:0048878 306 0.028
response to dietary excess GO:0002021 2 0.028
amine metabolic process GO:0009308 44 0.028
regulation of kinase activity GO:0043549 314 0.028
multicellular organismal aging GO:0010259 3 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
single organism reproductive process GO:0044702 98 0.026
organophosphate catabolic process GO:0046434 430 0.026
cellular amine metabolic process GO:0044106 41 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
maintenance of location GO:0051235 112 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
cellular amino acid metabolic process GO:0006520 116 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
oogenesis GO:0048477 2 0.024
cilium morphogenesis GO:0060271 75 0.024
cellular ketone metabolic process GO:0042180 80 0.023
regulation of protein kinase activity GO:0045859 289 0.023
rho protein signal transduction GO:0007266 26 0.023
cell division GO:0051301 168 0.023
mitotic cell cycle process GO:1903047 286 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
regulation of protein localization GO:0032880 296 0.022
positive regulation of apoptotic process GO:0043065 246 0.022
protein catabolic process GO:0030163 325 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
mitotic cell cycle GO:0000278 326 0.021
spermatid differentiation GO:0048515 4 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
cellular macromolecule catabolic process GO:0044265 380 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
nucleoside monophosphate catabolic process GO:0009125 159 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
negative regulation of cell cycle process GO:0010948 121 0.020
regulation of cellular response to stress GO:0080135 244 0.019
organelle assembly GO:0070925 176 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
regulation of cytoskeleton organization GO:0051493 177 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.019
determination of adult lifespan GO:0008340 2 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.018
reproduction GO:0000003 63 0.018
atp metabolic process GO:0046034 176 0.018
dna geometric change GO:0032392 32 0.018
male sex differentiation GO:0046661 25 0.018
regulation of cell division GO:0051302 116 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
positive regulation of organelle organization GO:0010638 195 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of protein transport GO:0051223 213 0.017
regulation of microtubule based process GO:0032886 74 0.017
positive regulation of kinase activity GO:0033674 204 0.017
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
negative regulation of catalytic activity GO:0043086 335 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
actin filament based process GO:0030029 224 0.016
development of primary male sexual characteristics GO:0046546 23 0.016
positive regulation of neural precursor cell proliferation GO:2000179 2 0.016
apoptotic signaling pathway GO:0097190 268 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
cell adhesion GO:0007155 325 0.016
growth GO:0040007 202 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
regulation of proteolysis GO:0030162 293 0.015
response to wounding GO:0009611 168 0.015
regulation of cell cycle process GO:0010564 266 0.015
myeloid cell differentiation GO:0030099 117 0.015
protein targeting GO:0006605 187 0.015
positive regulation of immune system process GO:0002684 283 0.015
intracellular protein transport GO:0006886 270 0.015
positive regulation of transport GO:0051050 336 0.015
wnt signaling pathway GO:0016055 156 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
locomotory behavior GO:0007626 1 0.015
i kappab kinase nf kappab signaling GO:0007249 166 0.015
regulation of dna replication GO:0006275 68 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
tissue regeneration GO:0042246 3 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
negative regulation of t cell apoptotic process GO:0070233 4 0.014
positive regulation of meiotic cell cycle GO:0051446 2 0.014
regulation of protein catabolic process GO:0042176 155 0.014
response to cytokine GO:0034097 232 0.014
cellular response to cytokine stimulus GO:0071345 181 0.013
cell development GO:0048468 328 0.013
nucleotide catabolic process GO:0009166 408 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
segmentation GO:0035282 4 0.013
biological adhesion GO:0022610 331 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
cell morphogenesis GO:0000902 296 0.013
response to oxygen containing compound GO:1901700 369 0.013
positive regulation of cell death GO:0010942 263 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
protein maturation GO:0051604 233 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
blastocyst development GO:0001824 3 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
response to inorganic substance GO:0010035 127 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
negative regulation of transferase activity GO:0051348 124 0.013
positive regulation of ras gtpase activity GO:0032320 117 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
negative regulation of protein processing GO:0010955 142 0.012
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.012
cell cycle checkpoint GO:0000075 117 0.012
nucleoside catabolic process GO:0009164 408 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
cilium organization GO:0044782 68 0.012
recombinational repair GO:0000725 50 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
response to organonitrogen compound GO:0010243 156 0.012
hemopoiesis GO:0030097 180 0.012
microtubule based process GO:0007017 210 0.012
oxidation reduction process GO:0055114 396 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.011
secretion by cell GO:0032940 226 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
dephosphorylation GO:0016311 209 0.011
ras protein signal transduction GO:0007265 73 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
response to radiation GO:0009314 151 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
negative regulation of catabolic process GO:0009895 104 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
positive regulation of catabolic process GO:0009896 310 0.011
positive regulation of transferase activity GO:0051347 227 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
cytoplasmic transport GO:0016482 379 0.011
cellular response to ionizing radiation GO:0071479 32 0.011
regulation of cytokine production GO:0001817 232 0.011
peripheral nervous system development GO:0007422 2 0.011
spermatid development GO:0007286 4 0.011
circulatory system development GO:0072359 262 0.011
cellular component morphogenesis GO:0032989 314 0.011
chromatin organization GO:0006325 351 0.011
regulation of leukocyte proliferation GO:0070663 67 0.011
maintenance of protein location GO:0045185 57 0.011
cellular response to oxygen containing compound GO:1901701 276 0.010
reproductive process GO:0022414 106 0.010
neuromuscular junction development GO:0007528 3 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
extrinsic apoptotic signaling pathway GO:0097191 119 0.010
neuroblast proliferation GO:0007405 4 0.010
cell projection morphogenesis GO:0048858 129 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
actin filament based movement GO:0030048 17 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
compound eye development GO:0048749 1 0.010
response to extracellular stimulus GO:0009991 85 0.010
anterior posterior axis specification GO:0009948 2 0.010
membrane organization GO:0061024 292 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
meiotic cell cycle process GO:1903046 8 0.010

FANCM disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.998
bone marrow disease DOID:4961 31 0.998
hematopoietic system disease DOID:74 100 0.998
congenital hypoplastic anemia DOID:1342 26 0.979
aplastic anemia DOID:12449 30 0.979
fanconi s anemia DOID:13636 16 0.979
anemia DOID:2355 55 0.979
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
nervous system disease DOID:863 431 0.014
eye disease DOID:5614 149 0.011
organ system cancer DOID:0050686 164 0.011
disease of metabolism DOID:0014667 295 0.010