Homo sapiens

205 known processes

PRKCA

protein kinase C, alpha

(Aliases: PKC-alpha,AAG6,PKCA,PRKACA,MGC129900,MGC129901)

PRKCA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular glucuronidation GO:0052695 16 0.999
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.996
Human
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 4 0.995
regulation of cellular glucuronidation GO:2001029 5 0.989
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.986
amine metabolic process GO:0009308 44 0.985
regulation of cellular amine metabolic process GO:0033238 11 0.983
cellular amine metabolic process GO:0044106 41 0.983
ameboidal type cell migration GO:0001667 135 0.982
uronic acid metabolic process GO:0006063 16 0.982
Human
cellular ketone metabolic process GO:0042180 80 0.979
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.965
positive regulation of mapk cascade GO:0043410 190 0.962
cellular amino acid metabolic process GO:0006520 116 0.962
positive regulation of phosphorylation GO:0042327 394 0.957
Mouse
metal ion transport GO:0030001 272 0.950
peptidyl threonine phosphorylation GO:0018107 41 0.948
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.948
regulation of cell cycle GO:0051726 393 0.938
enzyme linked receptor protein signaling pathway GO:0007167 303 0.935
Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.933
Mouse
peptidyl threonine modification GO:0018210 45 0.931
covalent chromatin modification GO:0016569 254 0.928
negative regulation of programmed cell death GO:0043069 321 0.923
peptidyl tyrosine phosphorylation GO:0018108 170 0.921
Mouse
glucuronate metabolic process GO:0019585 16 0.918
Human
positive regulation of locomotion GO:0040017 186 0.916
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.915
Human
secretion GO:0046903 254 0.913
negative regulation of apoptotic process GO:0043066 316 0.911
regulation of locomotion GO:0040012 329 0.905
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.903
Human
negative regulation of cell death GO:0060548 345 0.900
peptidyl serine modification GO:0018209 106 0.895
Human Mouse Worm
regulation of protein complex assembly GO:0043254 147 0.893
regulation of cell motility GO:2000145 299 0.884
cellular response to endogenous stimulus GO:0071495 336 0.880
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.879
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.864
regulation of cell adhesion GO:0030155 166 0.860
peptidyl serine phosphorylation GO:0018105 101 0.856
Human Mouse Worm
regulation of glial cell proliferation GO:0060251 4 0.855
Human
positive regulation of angiogenesis GO:0045766 51 0.847
positive regulation of cell motility GO:2000147 177 0.846
negative regulation of cellular protein metabolic process GO:0032269 353 0.845
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 128 0.842
Mouse
mapk cascade GO:0000165 288 0.832
Mouse
histone phosphorylation GO:0016572 16 0.829
epithelial cell migration GO:0010631 119 0.826
negative regulation of transport GO:0051051 176 0.823
Mouse
negative regulation of protein modification process GO:0031400 200 0.821
Mouse
angiogenesis GO:0001525 147 0.816
locomotory behavior GO:0007626 1 0.807
immune response activating signal transduction GO:0002757 90 0.799
Human
regulation of cell differentiation GO:0045595 393 0.798
Human Mouse
signal transduction by phosphorylation GO:0023014 297 0.798
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.797
negative regulation of muscle contraction GO:0045932 3 0.794
regulation of response to external stimulus GO:0032101 222 0.794
neurotransmitter secretion GO:0007269 4 0.792
regulation of cell development GO:0060284 161 0.790
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.787
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.781
regulation of cell migration GO:0030334 289 0.780
regulation of small gtpase mediated signal transduction GO:0051056 156 0.778
metal ion homeostasis GO:0055065 169 0.776
Mouse
response to cytokine GO:0034097 232 0.772
regulation of mapk cascade GO:0043408 262 0.769
Mouse
calcium ion transport GO:0006816 147 0.766
regulation of cell cell adhesion GO:0022407 57 0.765
oxidation reduction process GO:0055114 396 0.756
negative regulation of phosphate metabolic process GO:0045936 267 0.755
Mouse
cardiovascular system development GO:0072358 262 0.751
cellular metal ion homeostasis GO:0006875 146 0.742
Mouse
response to external biotic stimulus GO:0043207 261 0.741
epithelium migration GO:0090132 119 0.735
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.735
Human
single organism carbohydrate metabolic process GO:0044723 193 0.727
Human
regulation of lipid metabolic process GO:0019216 96 0.725
positive regulation of epithelial cell migration GO:0010634 55 0.723
regulation of carbohydrate metabolic process GO:0006109 54 0.714
Human
cellular component morphogenesis GO:0032989 314 0.710
response to organonitrogen compound GO:0010243 156 0.699
Mouse
response to biotic stimulus GO:0009607 276 0.699
endothelial cell migration GO:0043542 86 0.694
cytoplasmic transport GO:0016482 379 0.690
ras protein signal transduction GO:0007265 73 0.689
coagulation GO:0050817 78 0.688
cell type specific apoptotic process GO:0097285 125 0.683
cellular macromolecule catabolic process GO:0044265 380 0.679
determination of adult lifespan GO:0008340 2 0.674
growth GO:0040007 202 0.666
g protein coupled receptor signaling pathway GO:0007186 207 0.665
Fly
cell development GO:0048468 328 0.663
Human
cellular protein complex assembly GO:0043623 188 0.662
regulation of anatomical structure morphogenesis GO:0022603 286 0.661
regulation of endothelial cell proliferation GO:0001936 56 0.660
generation of neurons GO:0048699 152 0.660
Human
neuromuscular junction development GO:0007528 3 0.655
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.651
positive regulation of mitotic cell cycle GO:0045931 60 0.642
positive regulation of cellular component movement GO:0051272 181 0.641
positive regulation of glial cell proliferation GO:0060252 2 0.640
Human
response to wounding GO:0009611 168 0.637
cellular response to molecule of bacterial origin GO:0071219 62 0.631
protein polymerization GO:0051258 71 0.628
regulation of cell cycle process GO:0010564 266 0.628
Human
divalent metal ion transport GO:0070838 152 0.625
secretion by cell GO:0032940 226 0.623
divalent inorganic cation transport GO:0072511 158 0.621
positive regulation of cell cycle GO:0045787 140 0.619
tachykinin receptor signaling pathway GO:0007217 3 0.618
lipid metabolic process GO:0006629 381 0.616
regulation of secretion by cell GO:1903530 177 0.612
response to bacterium GO:0009617 144 0.611
positive regulation of b cell receptor signaling pathway GO:0050861 1 0.604
Human
monocarboxylic acid metabolic process GO:0032787 185 0.599
Human
regulation of cellular component movement GO:0051270 334 0.598
regulation of apoptotic signaling pathway GO:2001233 175 0.598
gliogenesis GO:0042063 21 0.595
Human
regulation of nucleoside metabolic process GO:0009118 209 0.592
regulation of establishment of protein localization GO:0070201 242 0.587
vesicle mediated transport GO:0016192 371 0.579
Fly
regulation of blood coagulation GO:0030193 42 0.578
modification dependent macromolecule catabolic process GO:0043632 212 0.577
positive regulation of organelle organization GO:0010638 195 0.573
protein maturation GO:0051604 233 0.568
response to growth factor GO:0070848 205 0.565
regulation of cellular component biogenesis GO:0044087 281 0.563
Human Mouse
positive regulation of transport GO:0051050 336 0.560
single organismal cell cell adhesion GO:0016337 148 0.560
positive regulation of cellular component organization GO:0051130 376 0.551
peptidyl tyrosine modification GO:0018212 170 0.549
Mouse
regulation of epithelial cell migration GO:0010632 93 0.549
positive regulation of map kinase activity GO:0043406 80 0.546
regulation of protein polymerization GO:0032271 63 0.540
protein processing GO:0016485 226 0.534
regulation of ion transport GO:0043269 189 0.534
positive regulation of protein kinase activity GO:0045860 190 0.531
organophosphate catabolic process GO:0046434 430 0.527
regulation of protein processing GO:0070613 150 0.514
cell activation GO:0001775 213 0.512
cellular lipid metabolic process GO:0044255 303 0.511
hemostasis GO:0007599 76 0.510
regulation of actin polymerization or depolymerization GO:0008064 56 0.502
histone threonine phosphorylation GO:0035405 7 0.502
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.501
positive regulation of gliogenesis GO:0014015 4 0.497
Human
cellular response to growth factor stimulus GO:0071363 197 0.496
negative regulation of protein phosphorylation GO:0001933 140 0.496
Mouse
epithelial cell proliferation GO:0050673 128 0.493
response to organic cyclic compound GO:0014070 204 0.491
regulation of angiogenesis GO:0045765 92 0.490
cation transport GO:0006812 331 0.486
regulation of cytoskeleton organization GO:0051493 177 0.485
regulation of epithelial cell proliferation GO:0050678 113 0.478
rho protein signal transduction GO:0007266 26 0.474
vasculature development GO:0001944 181 0.474
cellular calcium ion homeostasis GO:0006874 117 0.472
Mouse
associative learning GO:0008306 1 0.470
leukotriene metabolic process GO:0006691 10 0.469
cell cell signaling GO:0007267 155 0.464
carbohydrate metabolic process GO:0005975 207 0.458
Human
system process GO:0003008 349 0.457
Mouse Fly
actin filament based process GO:0030029 224 0.457
neurogenesis GO:0022008 169 0.452
Human
circulatory system development GO:0072359 262 0.449
regulation of actin filament polymerization GO:0030833 50 0.446
positive regulation of programmed cell death GO:0043068 249 0.445
neuron differentiation GO:0030182 138 0.445
regulation of blood volume by renin angiotensin GO:0002016 1 0.445
ion homeostasis GO:0050801 230 0.444
Mouse
cellular cation homeostasis GO:0030003 163 0.444
Mouse
regulation of metal ion transport GO:0010959 120 0.442
regulation of actin filament based process GO:0032970 141 0.440
ribonucleoside triphosphate metabolic process GO:0009199 412 0.438
single organism cell adhesion GO:0098602 179 0.437
phototransduction visible light GO:0007603 2 0.437
Fly
regulation of cell division GO:0051302 116 0.432
Human
response to lipid GO:0033993 206 0.430
mitotic cell cycle process GO:1903047 286 0.424
cell morphogenesis GO:0000902 296 0.419
guanosine containing compound catabolic process GO:1901069 239 0.411
signal release GO:0023061 70 0.405
positive regulation of cell division GO:0051781 59 0.404
Human
neurological system process GO:0050877 163 0.403
Fly
regulation of body fluid levels GO:0050878 99 0.402
positive regulation of epithelial cell proliferation GO:0050679 65 0.400
tissue migration GO:0090130 119 0.399
cellular macromolecular complex assembly GO:0034622 324 0.399
regulation of protein localization GO:0032880 296 0.397
regulation of proteolysis GO:0030162 293 0.396
negative regulation of protein metabolic process GO:0051248 391 0.396
Mouse
cellular response to starvation GO:0009267 58 0.393
mitotic cell cycle GO:0000278 326 0.393
protein modification by small protein conjugation GO:0032446 342 0.393
modification dependent protein catabolic process GO:0019941 209 0.391
regulation of cellular response to insulin stimulus GO:1900076 17 0.391
Mouse
regulation of ras protein signal transduction GO:0046578 155 0.388
cellular response to lipid GO:0071396 127 0.388
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.387
ubiquitin dependent protein catabolic process GO:0006511 206 0.387
positive regulation of nucleotide catabolic process GO:0030813 185 0.385
tor signaling GO:0031929 39 0.384
intracellular protein transport GO:0006886 270 0.383
immune system development GO:0002520 195 0.382
Mouse
negative regulation of phosphorylation GO:0042326 174 0.382
Mouse
protein catabolic process GO:0030163 325 0.379
purine nucleoside triphosphate catabolic process GO:0009146 392 0.372
positive regulation of actin filament polymerization GO:0030838 38 0.370
response to oxygen containing compound GO:1901700 369 0.369
regulation of secretion GO:0051046 194 0.368
nervous system development GO:0007399 293 0.368
Human
cell junction organization GO:0034330 79 0.365
actin filament polymerization GO:0030041 45 0.357
post embryonic development GO:0009791 2 0.351
negative regulation of catalytic activity GO:0043086 335 0.345
Mouse
regulation of membrane potential GO:0042391 95 0.344
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.341
cellular response to dna damage stimulus GO:0006974 379 0.336
regulation of growth GO:0040008 165 0.330
regulation of ion transmembrane transport GO:0034765 132 0.330
chromatin organization GO:0006325 351 0.325
positive regulation of cell proliferation GO:0008284 301 0.325
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.320
cellular protein catabolic process GO:0044257 261 0.319
regulation of cellular component size GO:0032535 82 0.318
regulation of actin cytoskeleton organization GO:0032956 116 0.317
positive regulation of apoptotic signaling pathway GO:2001235 70 0.316
chemotaxis GO:0006935 157 0.313
Mouse
histone modification GO:0016570 251 0.311
defense response GO:0006952 315 0.309
Mouse
regulation of response to wounding GO:1903034 101 0.306
female gamete generation GO:0007292 2 0.305
lipid catabolic process GO:0016042 84 0.300
ribonucleotide catabolic process GO:0009261 405 0.296
establishment of protein localization to organelle GO:0072594 172 0.295
negative regulation of protein processing GO:0010955 142 0.294
regulation of intracellular transport GO:0032386 195 0.293
response to other organism GO:0051707 261 0.293
regulation of rho protein signal transduction GO:0035023 79 0.290
positive regulation of immune response GO:0050778 159 0.289
Human
blood vessel endothelial cell migration GO:0043534 42 0.288
endothelial cell proliferation GO:0001935 65 0.287
regulation of neurogenesis GO:0050767 82 0.287
Human
chemical homeostasis GO:0048878 306 0.287
Mouse
response to nitrogen compound GO:1901698 184 0.284
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.282
blood vessel development GO:0001568 172 0.276
membrane organization GO:0061024 292 0.275
positive regulation of catabolic process GO:0009896 310 0.273
regulation of ion homeostasis GO:2000021 73 0.272
transmembrane transport GO:0055085 399 0.272
positive regulation of cell death GO:0010942 263 0.271
blood circulation GO:0008015 113 0.269
Mouse
positive regulation of cytoskeleton organization GO:0051495 83 0.268
actin polymerization or depolymerization GO:0008154 56 0.268
regulation of calcium ion transport GO:0051924 79 0.268
regulation of actin filament length GO:0030832 56 0.268
protein targeting GO:0006605 187 0.266
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.263
response to hormone GO:0009725 175 0.262
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.256
cell projection organization GO:0030030 252 0.255
oocyte development GO:0048599 1 0.254
neuron development GO:0048666 113 0.253
blood vessel morphogenesis GO:0048514 162 0.252
nitrogen compound transport GO:0071705 191 0.251
cellular response to cytokine stimulus GO:0071345 181 0.251
positive regulation of apoptotic process GO:0043065 246 0.250
negative regulation of multicellular organismal process GO:0051241 317 0.248
sequestering of metal ion GO:0051238 24 0.246
i kappab kinase nf kappab signaling GO:0007249 166 0.246
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.244
Human
oogenesis GO:0048477 2 0.243
wound healing GO:0042060 115 0.241
immune response GO:0006955 307 0.240
response to carbohydrate GO:0009743 21 0.238
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.238
insulin receptor signaling pathway GO:0008286 23 0.237
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.236
purine ribonucleoside catabolic process GO:0046130 398 0.234
cell cycle phase transition GO:0044770 173 0.233
synaptic vesicle exocytosis GO:0016079 3 0.233
positive regulation of cell adhesion GO:0045785 84 0.230
regulation of neuron differentiation GO:0045664 70 0.229
nucleocytoplasmic transport GO:0006913 176 0.224
regulation of lipid catabolic process GO:0050994 23 0.223
photoreceptor cell differentiation GO:0046530 2 0.223
chromatin modification GO:0016568 298 0.223
purine ribonucleotide catabolic process GO:0009154 404 0.222
guanosine containing compound metabolic process GO:1901068 244 0.220
cell projection morphogenesis GO:0048858 129 0.220
positive regulation of cellular component biogenesis GO:0044089 158 0.218
Mouse
erk1 and erk2 cascade GO:0070371 104 0.218
positive regulation of cellular catabolic process GO:0031331 284 0.217
negative regulation of cellular amine metabolic process GO:0033239 3 0.216
immune response regulating signaling pathway GO:0002764 97 0.216
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.215
actin cytoskeleton organization GO:0030036 207 0.214
cellular response to abiotic stimulus GO:0071214 117 0.208
Fly
cellular response to hormone stimulus GO:0032870 125 0.207
Mouse
monosaccharide metabolic process GO:0005996 74 0.206
Human
glycosyl compound catabolic process GO:1901658 413 0.206
regulation of coagulation GO:0050818 44 0.205
regulation of transferase activity GO:0051338 355 0.204
Mouse
negative regulation of cell proliferation GO:0008285 228 0.202
Mouse
response to starvation GO:0042594 59 0.202
positive regulation of secretion by cell GO:1903532 108 0.199
organelle localization GO:0051640 84 0.198
regulation of peptidase activity GO:0052547 180 0.198
cytokine mediated signaling pathway GO:0019221 109 0.197
sequestering of calcium ion GO:0051208 17 0.196
ribonucleoside catabolic process GO:0042454 406 0.195
defense response to other organism GO:0098542 129 0.194
multicellular organismal aging GO:0010259 3 0.194
response to decreased oxygen levels GO:0036293 96 0.194
purine nucleoside triphosphate metabolic process GO:0009144 412 0.192
tricarboxylic acid metabolic process GO:0072350 4 0.190
regulation of protein maturation GO:1903317 150 0.185
circulatory system process GO:0003013 113 0.185
Mouse
biological adhesion GO:0022610 331 0.184
protein autophosphorylation GO:0046777 123 0.182
Mouse
behavior GO:0007610 112 0.181
Mouse
protein ubiquitination GO:0016567 314 0.181
negative regulation of protein maturation GO:1903318 142 0.181
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.180
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.180
memory GO:0007613 3 0.179
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.179
nucleoside triphosphate catabolic process GO:0009143 394 0.179
negative regulation of phosphorus metabolic process GO:0010563 267 0.179
Mouse
regulation of multi organism process GO:0043900 157 0.177
cellular response to peptide GO:1901653 59 0.177
Mouse
cellular response to organonitrogen compound GO:0071417 124 0.175
Mouse
apoptotic signaling pathway GO:0097190 268 0.175
Mouse
lipid biosynthetic process GO:0008610 177 0.174
positive regulation of nucleotide metabolic process GO:0045981 230 0.172
positive regulation of transferase activity GO:0051347 227 0.172
positive regulation of developmental process GO:0051094 314 0.169
regulation of nucleotide metabolic process GO:0006140 269 0.169
regulation of platelet aggregation GO:0090330 4 0.169
organonitrogen compound biosynthetic process GO:1901566 200 0.166
negative regulation of proteolysis GO:0045861 132 0.166
response to abiotic stimulus GO:0009628 336 0.165
Fly
positive regulation of endothelial cell proliferation GO:0001938 37 0.161
regulation of nervous system development GO:0051960 88 0.161
Human
actin filament organization GO:0007015 128 0.160
desmosome organization GO:0002934 5 0.159
hexose transport GO:0008645 30 0.159
Mouse
negative regulation of cellular component organization GO:0051129 235 0.158
b cell receptor signaling pathway GO:0050853 18 0.156
Human
oocyte differentiation GO:0009994 2 0.156
positive regulation of protein complex assembly GO:0031334 86 0.156
single organism cellular localization GO:1902580 332 0.155
cellular carbohydrate metabolic process GO:0044262 84 0.155
Human
neuron projection development GO:0031175 106 0.154
cytosolic calcium ion homeostasis GO:0051480 89 0.154
regulation of endopeptidase activity GO:0052548 170 0.152
cellular chemical homeostasis GO:0055082 180 0.151
Mouse
mesendoderm development GO:0048382 1 0.151
leukocyte activation GO:0045321 164 0.151
regulation of protein import into nucleus GO:0042306 78 0.151
regulation of cell morphogenesis GO:0022604 153 0.151
regulation of wound healing GO:0061041 56 0.151
regulation of homeostatic process GO:0032844 121 0.150
negative regulation of kinase activity GO:0033673 106 0.149
Mouse
cellular homeostasis GO:0019725 196 0.147
Mouse
maintenance of location GO:0051235 112 0.147
extrinsic apoptotic signaling pathway GO:0097191 119 0.147
regulation of nucleocytoplasmic transport GO:0046822 98 0.145
nucleoside phosphate catabolic process GO:1901292 412 0.145
rac protein signal transduction GO:0016601 12 0.144
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.144
Mouse
muscle cell proliferation GO:0033002 35 0.144
regulation of rhodopsin mediated signaling pathway GO:0022400 1 0.143
Fly
cell division GO:0051301 168 0.142
Human
neurotransmitter transport GO:0006836 10 0.141
regulation of map kinase activity GO:0043405 108 0.141
Mouse
response to oxygen levels GO:0070482 100 0.141
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.141
positive regulation of lipid metabolic process GO:0045834 50 0.139
regulation of gtp catabolic process GO:0033124 180 0.137
regulation of cell activation GO:0050865 125 0.137
regulation of protein catabolic process GO:0042176 155 0.136
long term memory GO:0007616 2 0.136
positive regulation of neurogenesis GO:0050769 49 0.135
Human
regulation of protein transport GO:0051223 213 0.135
cellular response to nutrient levels GO:0031669 69 0.135
regulation of glucose transport GO:0010827 23 0.133
Mouse
regulation of neurotransmitter levels GO:0001505 15 0.133
organic hydroxy compound metabolic process GO:1901615 147 0.132
protein localization to nucleus GO:0034504 136 0.131
regulation of rho gtpase activity GO:0032319 66 0.130
rhodopsin mediated signaling pathway GO:0016056 1 0.130
Fly
negative regulation of organelle organization GO:0010639 126 0.129
wnt signaling pathway GO:0016055 156 0.128
cell cell junction organization GO:0045216 69 0.128
insulin like growth factor receptor signaling pathway GO:0048009 13 0.128
gtp catabolic process GO:0006184 237 0.127
forebrain generation of neurons GO:0021872 3 0.127
nucleoside catabolic process GO:0009164 408 0.126
positive regulation of cell cycle process GO:0090068 106 0.126
Human
positive regulation of cell substrate adhesion GO:0010811 37 0.125
regulation of protein serine threonine kinase activity GO:0071900 179 0.124
Mouse
response to extracellular stimulus GO:0009991 85 0.123
positive regulation of hydrolase activity GO:0051345 331 0.123
cellular response to external stimulus GO:0071496 111 0.123
anatomical structure formation involved in morphogenesis GO:0048646 284 0.123
internal protein amino acid acetylation GO:0006475 101 0.123
regulation of muscle system process GO:0090257 53 0.123
Mouse
platelet activation GO:0030168 44 0.123
synaptic transmission GO:0007268 61 0.121
positive regulation of synaptic transmission GO:0050806 4 0.121
peptidyl lysine modification GO:0018205 144 0.121
nucleotide catabolic process GO:0009166 408 0.120
regulation of receptor activity GO:0010469 47 0.119
innate immune response GO:0045087 178 0.119
activation of protein kinase activity GO:0032147 90 0.118
exocytosis GO:0006887 71 0.117
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.116
phospholipid metabolic process GO:0006644 99 0.116
aging GO:0007568 66 0.116
establishment of organelle localization GO:0051656 59 0.116
negative regulation of striated muscle contraction GO:0045988 2 0.116
gtp metabolic process GO:0046039 239 0.115
nucleoside monophosphate metabolic process GO:0009123 191 0.115
regulation of kinase activity GO:0043549 314 0.115
Mouse
negative regulation of secretion GO:0051048 58 0.114
positive regulation of protein polymerization GO:0032273 45 0.113
response to peptide hormone GO:0043434 61 0.113
Mouse
purine containing compound catabolic process GO:0072523 411 0.113
response to drug GO:0042493 81 0.112
regulation of purine nucleotide catabolic process GO:0033121 205 0.111
regulation of neurotransmitter secretion GO:0046928 3 0.111
immune effector process GO:0002252 159 0.110
positive regulation of immune system process GO:0002684 283 0.110
Human Mouse
regulation of wnt signaling pathway GO:0030111 123 0.109
lipid localization GO:0010876 106 0.108
protein kinase b signaling GO:0043491 69 0.108
regulation of purine nucleotide metabolic process GO:1900542 264 0.107
response to oxidative stress GO:0006979 121 0.107
motor neuron axon guidance GO:0008045 2 0.107
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.107
positive regulation of cell development GO:0010720 92 0.107
Human
protein import GO:0017038 130 0.106
protein import into nucleus GO:0006606 104 0.105
blood coagulation GO:0007596 76 0.105
taxis GO:0042330 157 0.104
Mouse
neuron projection morphogenesis GO:0048812 50 0.104
establishment of protein localization to membrane GO:0090150 121 0.104
cellular response to parathyroid hormone stimulus GO:0071374 2 0.103
cellular defense response GO:0006968 2 0.103
peptidyl lysine acetylation GO:0018394 101 0.103
regulation of erk1 and erk2 cascade GO:0070372 99 0.101
negative regulation of endopeptidase activity GO:0010951 84 0.101
organic anion transport GO:0015711 103 0.100
negative regulation of cytoskeleton organization GO:0051494 45 0.100
calcium ion homeostasis GO:0055074 122 0.100
Mouse
protein polyubiquitination GO:0000209 110 0.100
regulation of transmembrane transport GO:0034762 139 0.099
dephosphorylation GO:0016311 209 0.099
regulation of neuron migration GO:2001222 3 0.099
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.098
cognition GO:0050890 43 0.097
reactive oxygen species metabolic process GO:0072593 75 0.097
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.097
negative regulation of developmental process GO:0051093 247 0.096
positive regulation of cell activation GO:0050867 81 0.096
regulation of calcium ion transport into cytosol GO:0010522 33 0.096
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.096
internal peptidyl lysine acetylation GO:0018393 97 0.095
generation of precursor metabolites and energy GO:0006091 68 0.094
negative regulation of platelet aggregation GO:0090331 3 0.094
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.093
protein localization to organelle GO:0033365 280 0.093
response to radiation GO:0009314 151 0.093
Fly
programmed cell death in response to reactive oxygen species GO:0097468 4 0.093
purine nucleotide catabolic process GO:0006195 405 0.092
glucose transport GO:0015758 30 0.092
Mouse
regulation of blood pressure GO:0008217 30 0.092
response to ethanol GO:0045471 11 0.092
Fly
response to hypoxia GO:0001666 96 0.091
regulation of blood circulation GO:1903522 59 0.091
Mouse
peptide transport GO:0015833 74 0.090
adaptation of signaling pathway GO:0023058 7 0.090
Fly
negative regulation of protein kinase activity GO:0006469 98 0.090
Mouse
regulation of protein kinase activity GO:0045859 289 0.088
Mouse
activation of immune response GO:0002253 114 0.088
Human
response to alcohol GO:0097305 64 0.088
Fly
regulation of intracellular protein transport GO:0033157 123 0.088
positive regulation of cell differentiation GO:0045597 211 0.088
Human Mouse
cell projection assembly GO:0030031 126 0.088
hematopoietic or lymphoid organ development GO:0048534 186 0.088
Mouse
polysaccharide metabolic process GO:0005976 33 0.087
regulation of cellular response to growth factor stimulus GO:0090287 76 0.087

PRKCA disease predictions

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 36 0.259
immune system disease DOID:2914 155 0.259