Homo sapiens

53 known processes

HIST1H3E

histone cluster 1, H3e

(Aliases: H3.1,H3/d,H3FD)

HIST1H3E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 351 0.091
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.077
dna replication dependent nucleosome assembly GO:0006335 32 0.077
dna replication independent nucleosome assembly GO:0006336 27 0.066
Human
regulation of cell differentiation GO:0045595 393 0.064
chromatin modification GO:0016568 298 0.061
cellular macromolecular complex assembly GO:0034622 324 0.061
post embryonic development GO:0009791 2 0.060
negative regulation of megakaryocyte differentiation GO:0045653 16 0.059
histone modification GO:0016570 251 0.054
dna replication independent nucleosome organization GO:0034724 27 0.052
Human
cellular response to dna damage stimulus GO:0006974 379 0.050
Yeast
negative regulation of multicellular organismal process GO:0051241 317 0.048
regulation of cellular ketone metabolic process GO:0010565 50 0.048
cellular amino acid metabolic process GO:0006520 116 0.047
chromatin assembly GO:0031497 61 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
cellular ketone metabolic process GO:0042180 80 0.045
covalent chromatin modification GO:0016569 254 0.042
cellular amine metabolic process GO:0044106 41 0.041
negative regulation of developmental process GO:0051093 247 0.041
dna repair GO:0006281 198 0.041
Yeast
regulation of cellular amine metabolic process GO:0033238 11 0.039
nucleosome assembly GO:0006334 50 0.039
amine metabolic process GO:0009308 44 0.039
hemopoiesis GO:0030097 180 0.038
histone lysine methylation GO:0034968 50 0.038
macromolecule methylation GO:0043414 97 0.037
determination of adult lifespan GO:0008340 2 0.036
negative regulation of protein metabolic process GO:0051248 391 0.035
Yeast
immune system development GO:0002520 195 0.035
multicellular organismal aging GO:0010259 3 0.034
nucleosome organization GO:0034728 66 0.034
chromatin assembly or disassembly GO:0006333 78 0.034
female gamete generation GO:0007292 2 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
anatomical structure formation involved in morphogenesis GO:0048646 284 0.033
Yeast
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
protein catabolic process GO:0030163 325 0.033
Yeast
defense response GO:0006952 315 0.032
hematopoietic or lymphoid organ development GO:0048534 186 0.032
regulation of megakaryocyte differentiation GO:0045652 22 0.031
negative regulation of catalytic activity GO:0043086 335 0.030
segmentation GO:0035282 4 0.030
oogenesis GO:0048477 2 0.030
regulation of myeloid cell differentiation GO:0045637 81 0.030
cellular lipid metabolic process GO:0044255 303 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
Yeast
protein alkylation GO:0008213 74 0.029
locomotory behavior GO:0007626 1 0.028
histone methylation GO:0016571 60 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
Yeast
protein methylation GO:0006479 74 0.027
methylation GO:0032259 106 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
protein dna complex subunit organization GO:0071824 80 0.027
immune response GO:0006955 307 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
dna conformation change GO:0071103 113 0.026
regulation of cell cycle GO:0051726 393 0.025
Yeast
purine containing compound catabolic process GO:0072523 411 0.025
negative regulation of cell differentiation GO:0045596 171 0.025
negative regulation of immune system process GO:0002683 136 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
myeloid cell differentiation GO:0030099 117 0.024
response to abiotic stimulus GO:0009628 336 0.024
nucleotide catabolic process GO:0009166 408 0.024
cytoplasmic transport GO:0016482 379 0.024
ribonucleotide catabolic process GO:0009261 405 0.024
dna packaging GO:0006323 77 0.024
dna replication dependent nucleosome organization GO:0034723 32 0.024
response to other organism GO:0051707 261 0.023
organophosphate catabolic process GO:0046434 430 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
regulation of proteolysis GO:0030162 293 0.023
Yeast
positive regulation of phosphorylation GO:0042327 394 0.023
response to external biotic stimulus GO:0043207 261 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
regulation of cell cycle process GO:0010564 266 0.023
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
regulation of transferase activity GO:0051338 355 0.023
single organism membrane organization GO:0044802 268 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.022
innate immune response GO:0045087 178 0.022
neuromuscular junction development GO:0007528 3 0.022
protein processing GO:0016485 226 0.022
Yeast
regeneration GO:0031099 4 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
mapk cascade GO:0000165 288 0.022
single organism cellular localization GO:1902580 332 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
regulation of establishment of protein localization GO:0070201 242 0.021
regulation of protein kinase activity GO:0045859 289 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
carbohydrate metabolic process GO:0005975 207 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
anterior posterior axis specification GO:0009948 2 0.021
positive regulation of transport GO:0051050 336 0.021
cellular protein catabolic process GO:0044257 261 0.021
Yeast
protein ubiquitination GO:0016567 314 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
negative regulation of myeloid cell differentiation GO:0045638 42 0.021
regulation of response to external stimulus GO:0032101 222 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
Yeast
rna processing GO:0006396 255 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
protein dna complex assembly GO:0065004 64 0.020
histone h3 k79 methylation GO:0034729 2 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
response to oxygen containing compound GO:1901700 369 0.020
nucleoside catabolic process GO:0009164 408 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of cellular response to stress GO:0080135 244 0.020
intracellular protein transport GO:0006886 270 0.020
lipid metabolic process GO:0006629 381 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
protein maturation GO:0051604 233 0.020
Yeast
response to biotic stimulus GO:0009607 276 0.020
membrane organization GO:0061024 292 0.020
regulation of protein localization GO:0032880 296 0.020
regulation of locomotion GO:0040012 329 0.019
apoptotic signaling pathway GO:0097190 268 0.019
regulation of kinase activity GO:0043549 314 0.019
regulation of protein transport GO:0051223 213 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
cellular component morphogenesis GO:0032989 314 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
protein localization to organelle GO:0033365 280 0.019
modification dependent protein catabolic process GO:0019941 209 0.019
Yeast
system process GO:0003008 349 0.019
blastoderm segmentation GO:0007350 2 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
Yeast
positive regulation of catabolic process GO:0009896 310 0.019
mitotic cell cycle GO:0000278 326 0.019
Yeast
negative regulation of protein modification process GO:0031400 200 0.019
mrna metabolic process GO:0016071 175 0.019
regulation of gene expression epigenetic GO:0040029 73 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
hematopoietic progenitor cell differentiation GO:0002244 38 0.018
actin filament based process GO:0030029 224 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
nervous system development GO:0007399 293 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
Yeast
oocyte development GO:0048599 1 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
vesicle mediated transport GO:0016192 371 0.017
cell morphogenesis GO:0000902 296 0.017
mitotic cell cycle process GO:1903047 286 0.017
Yeast
negative regulation of cell death GO:0060548 345 0.017
regulation of mapk cascade GO:0043408 262 0.017
response to bacterium GO:0009617 144 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
oocyte differentiation GO:0009994 2 0.017
organ formation GO:0048645 3 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
hindbrain development GO:0030902 3 0.017
cell adhesion GO:0007155 325 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
oxidation reduction process GO:0055114 396 0.017
ras protein signal transduction GO:0007265 73 0.017
peripheral nervous system development GO:0007422 2 0.017
rho protein signal transduction GO:0007266 26 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
positive regulation of cell death GO:0010942 263 0.017
cell projection organization GO:0030030 252 0.017
spermatid differentiation GO:0048515 4 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
Yeast
regulation of cytokine production GO:0001817 232 0.016
multi organism cellular process GO:0044764 156 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
cytokine production GO:0001816 247 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
positive regulation of organelle organization GO:0010638 195 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
negative regulation of cell cycle GO:0045786 193 0.016
Yeast
negative regulation of protein processing GO:0010955 142 0.016
Yeast
dephosphorylation GO:0016311 209 0.016
viral process GO:0016032 146 0.016
biological adhesion GO:0022610 331 0.016
viral life cycle GO:0019058 132 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
photoreceptor cell differentiation GO:0046530 2 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
tripartite regional subdivision GO:0007351 2 0.015
regulation of cellular component movement GO:0051270 334 0.015
positive regulation of developmental process GO:0051094 314 0.015
associative learning GO:0008306 1 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
Yeast
regulation of growth GO:0040008 165 0.015
Human
metal ion transport GO:0030001 272 0.015
response to lipid GO:0033993 206 0.015
adult locomotory behavior GO:0008344 1 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
Yeast
regulation of nucleotide metabolic process GO:0006140 269 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
endomembrane system organization GO:0010256 196 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
regulation of secretion GO:0051046 194 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
transmembrane transport GO:0055085 399 0.015
regulation of protein catabolic process GO:0042176 155 0.015
Yeast
memory GO:0007613 3 0.015
secretion GO:0046903 254 0.015
protein targeting GO:0006605 187 0.015
response to cytokine GO:0034097 232 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
secretion by cell GO:0032940 226 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of intracellular transport GO:0032386 195 0.015
negative regulation of hydrolase activity GO:0051346 182 0.014
gtp metabolic process GO:0046039 239 0.014
response to uv GO:0009411 73 0.014
cell growth GO:0016049 160 0.014
Human
interspecies interaction between organisms GO:0044419 156 0.014
regulation of multi organism process GO:0043900 157 0.014
compound eye development GO:0048749 1 0.014
regulation of protein maturation GO:1903317 150 0.014
Yeast
regulation of apoptotic signaling pathway GO:2001233 175 0.014
mrna processing GO:0006397 133 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
response to radiation GO:0009314 151 0.014
positive regulation of immune system process GO:0002684 283 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
defense response to other organism GO:0098542 129 0.014
somitogenesis GO:0001756 2 0.014
gtp catabolic process GO:0006184 237 0.014
maintenance of location GO:0051235 112 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
regulation of cell motility GO:2000145 299 0.014
epithelium development GO:0060429 227 0.014
regulation of protein processing GO:0070613 150 0.014
Yeast
negative regulation of transferase activity GO:0051348 124 0.014
lipid biosynthetic process GO:0008610 177 0.014
chemical homeostasis GO:0048878 306 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
spermatid development GO:0007286 4 0.013
response to axon injury GO:0048678 1 0.013
positive regulation of transferase activity GO:0051347 227 0.013
motor neuron axon guidance GO:0008045 2 0.013
cell fate determination GO:0001709 3 0.013
endosomal transport GO:0016197 129 0.013
nerve development GO:0021675 4 0.013
cellular protein complex assembly GO:0043623 188 0.013
specification of organ identity GO:0010092 3 0.013
rhythmic behavior GO:0007622 2 0.013
regulation of t helper 2 cell cytokine production GO:2000551 2 0.013
negative regulation of protein maturation GO:1903318 142 0.013
Yeast
regulation of dna metabolic process GO:0051052 153 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
megakaryocyte differentiation GO:0030219 25 0.013
actin filament based movement GO:0030048 17 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
reproductive process GO:0022414 106 0.013
Yeast
nitrogen compound transport GO:0071705 191 0.013
salivary gland morphogenesis GO:0007435 4 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
glycoprotein metabolic process GO:0009100 110 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
negative regulation of proteolysis GO:0045861 132 0.013
Yeast
cellular component disassembly GO:0022411 92 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
microtubule based process GO:0007017 210 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
single organism reproductive process GO:0044702 98 0.013
Yeast
cell cycle checkpoint GO:0000075 117 0.013
Yeast
regulation of viral process GO:0050792 103 0.013
tissue regeneration GO:0042246 3 0.013
cellular homeostasis GO:0019725 196 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
protein localization to membrane GO:0072657 160 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
regulation of gtpase activity GO:0043087 180 0.012
peptidyl lysine modification GO:0018205 144 0.012
circulatory system development GO:0072359 262 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
mating GO:0007618 1 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
actin mediated cell contraction GO:0070252 12 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
regulation of immune response GO:0050776 201 0.012
mitochondrion organization GO:0007005 156 0.012
cell division GO:0051301 168 0.012
Yeast
epithelial cell differentiation GO:0030855 141 0.012
fatty acid metabolic process GO:0006631 115 0.012
regulation of defense response GO:0031347 154 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
growth GO:0040007 202 0.012
Human
negative regulation of transport GO:0051051 176 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
ion homeostasis GO:0050801 230 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
cardiovascular system development GO:0072358 262 0.012
cation transport GO:0006812 331 0.012
thymus development GO:0048538 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
Yeast
circadian behavior GO:0048512 2 0.012
limbic system development GO:0021761 3 0.012
negative regulation of t helper 2 cell cytokine production GO:2000552 2 0.012
cell activation GO:0001775 213 0.012
response to fungus GO:0009620 4 0.012
positive regulation of kinase activity GO:0033674 204 0.012
actin cytoskeleton organization GO:0030036 207 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
neuroblast proliferation GO:0007405 4 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
metencephalon development GO:0022037 2 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
positive regulation of protein transport GO:0051222 135 0.012
protein oligomerization GO:0051259 173 0.012
response to hormone GO:0009725 175 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
Yeast
cell development GO:0048468 328 0.012
negative regulation of organelle organization GO:0010639 126 0.012
Yeast
wnt signaling pathway GO:0016055 156 0.011
regulation of chromosome organization GO:0033044 103 0.011
Yeast
myoblast fusion GO:0007520 1 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
regulation of peptidase activity GO:0052547 180 0.011
response to growth factor GO:0070848 205 0.011
response to virus GO:0009615 126 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
Yeast
positive regulation of locomotion GO:0040017 186 0.011
regulation of secretion by cell GO:1903530 177 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
Yeast
inner ear morphogenesis GO:0042472 4 0.011
sequestering of metal ion GO:0051238 24 0.011
regulation of cell migration GO:0030334 289 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
stem cell division GO:0017145 2 0.011
protein acylation GO:0043543 138 0.011
regulation of cell adhesion GO:0030155 166 0.011
regulation of cell division GO:0051302 116 0.011
Yeast
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
nuclear transport GO:0051169 179 0.011
response to organic cyclic compound GO:0014070 204 0.011
response to nitrogen compound GO:1901698 184 0.011
rna interference GO:0016246 4 0.011
sensory perception of smell GO:0007608 2 0.011
response to wounding GO:0009611 168 0.011
small molecule biosynthetic process GO:0044283 157 0.011
regulation of protein complex assembly GO:0043254 147 0.011
cranial nerve development GO:0021545 4 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
protein autophosphorylation GO:0046777 123 0.011
organelle assembly GO:0070925 176 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
somatic stem cell maintenance GO:0035019 4 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
leukocyte activation GO:0045321 164 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
cell part morphogenesis GO:0032990 137 0.011
plasma membrane organization GO:0007009 115 0.011
negative regulation of catabolic process GO:0009895 104 0.010
Yeast
chemotaxis GO:0006935 157 0.010
negative regulation of multi organism process GO:0043901 92 0.010
protein modification by small protein removal GO:0070646 92 0.010
lipid catabolic process GO:0016042 84 0.010
visual behavior GO:0007632 2 0.010
negative regulation of kinase activity GO:0033673 106 0.010
neural tube closure GO:0001843 3 0.010
cellular response to external stimulus GO:0071496 111 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
positive regulation of cell cycle GO:0045787 140 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
protein complex disassembly GO:0043241 52 0.010
response to extracellular stimulus GO:0009991 85 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
neurogenesis GO:0022008 169 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
regulation of cellular protein catabolic process GO:1903362 96 0.010
Yeast
cell cycle phase transition GO:0044770 173 0.010
Yeast
nucleus localization GO:0051647 1 0.010
regulation of cell development GO:0060284 161 0.010
developmental programmed cell death GO:0010623 3 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
cell substrate adhesion GO:0031589 132 0.010
atp metabolic process GO:0046034 176 0.010
meiosis i GO:0007127 4 0.010
protein import GO:0017038 130 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
Yeast

HIST1H3E disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.034
inherited metabolic disorder DOID:655 242 0.025
musculoskeletal system disease DOID:17 223 0.023
central nervous system disease DOID:331 186 0.021
nervous system disease DOID:863 431 0.021
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
organ system cancer DOID:0050686 164 0.019
sensory system disease DOID:0050155 203 0.017
immune system disease DOID:2914 155 0.016
neurodegenerative disease DOID:1289 102 0.014
muscular disease DOID:0080000 114 0.014
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
muscle tissue disease DOID:66 113 0.013
cardiovascular system disease DOID:1287 106 0.012
connective tissue disease DOID:65 109 0.012
myopathy DOID:423 104 0.012
retinal disease DOID:5679 118 0.012
hematopoietic system disease DOID:74 100 0.010
disease of mental health DOID:150 70 0.010
heart disease DOID:114 68 0.010
bone disease DOID:0080001 88 0.010