Homo sapiens

20 known processes

PMF1

polyamine-modulated factor 1

PMF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oogenesis GO:0048477 2 0.235
defense response GO:0006952 315 0.127
mitochondrion organization GO:0007005 156 0.091
cellular response to dna damage stimulus GO:0006974 379 0.090
female gamete generation GO:0007292 2 0.084
response to external biotic stimulus GO:0043207 261 0.078
response to abiotic stimulus GO:0009628 336 0.065
regulation of proteolysis GO:0030162 293 0.065
cell cycle phase transition GO:0044770 173 0.064
posttranscriptional regulation of gene expression GO:0010608 213 0.063
cellular macromolecule catabolic process GO:0044265 380 0.061
cell cell signaling GO:0007267 155 0.060
negative regulation of cell cycle process GO:0010948 121 0.060
regulation of cell cycle process GO:0010564 266 0.057
negative regulation of cell proliferation GO:0008285 228 0.057
regulation of mitotic cell cycle GO:0007346 189 0.055
regulation of cell cycle GO:0051726 393 0.055
negative regulation of protein metabolic process GO:0051248 391 0.054
dna damage checkpoint GO:0000077 68 0.052
regulation of secretion by cell GO:1903530 177 0.050
mitotic cell cycle phase transition GO:0044772 162 0.050
regulation of mapk cascade GO:0043408 262 0.049
response to other organism GO:0051707 261 0.047
negative regulation of cell cycle GO:0045786 193 0.047
regulation of cellular amine metabolic process GO:0033238 11 0.045
response to oxygen containing compound GO:1901700 369 0.044
purine nucleotide catabolic process GO:0006195 405 0.044
defense response to other organism GO:0098542 129 0.043
mitotic cell cycle process GO:1903047 286 0.043
immune response GO:0006955 307 0.041
post embryonic development GO:0009791 2 0.040
mapk cascade GO:0000165 288 0.038
signal transduction by phosphorylation GO:0023014 297 0.038
innate immune response GO:0045087 178 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.036
mitotic cell cycle checkpoint GO:0007093 68 0.035
regulation of cell cycle phase transition GO:1901987 126 0.033
negative regulation of mitotic cell cycle GO:0045930 102 0.033
small gtpase mediated signal transduction GO:0007264 78 0.032
regulation of protein catabolic process GO:0042176 155 0.032
response to biotic stimulus GO:0009607 276 0.031
response to cytokine GO:0034097 232 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
regulation of apoptotic signaling pathway GO:2001233 175 0.030
cellular amine metabolic process GO:0044106 41 0.030
neuromuscular junction development GO:0007528 3 0.030
protein catabolic process GO:0030163 325 0.030
reproductive process GO:0022414 106 0.030
negative regulation of protein phosphorylation GO:0001933 140 0.030
organophosphate catabolic process GO:0046434 430 0.029
negative regulation of cell cycle phase transition GO:1901988 89 0.029
negative regulation of cell death GO:0060548 345 0.029
protein modification by small protein removal GO:0070646 92 0.029
negative regulation of catalytic activity GO:0043086 335 0.028
cellular protein catabolic process GO:0044257 261 0.028
regulation of defense response GO:0031347 154 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
cell cycle checkpoint GO:0000075 117 0.027
negative regulation of multicellular organismal process GO:0051241 317 0.027
locomotory behavior GO:0007626 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
mitotic cell cycle GO:0000278 326 0.027
regulation of cellular response to stress GO:0080135 244 0.026
negative regulation of developmental process GO:0051093 247 0.026
regulation of kinase activity GO:0043549 314 0.025
response to bacterium GO:0009617 144 0.025
cellular ketone metabolic process GO:0042180 80 0.025
amine metabolic process GO:0009308 44 0.025
cell adhesion GO:0007155 325 0.025
regulation of translation GO:0006417 89 0.025
regulation of response to biotic stimulus GO:0002831 55 0.025
regulation of mitotic cell cycle phase transition GO:1901990 118 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
g2 dna damage checkpoint GO:0031572 26 0.024
single organism membrane organization GO:0044802 268 0.023
regulation of locomotion GO:0040012 329 0.023
regulation of cell growth GO:0001558 135 0.023
biological adhesion GO:0022610 331 0.023
nucleotide catabolic process GO:0009166 408 0.023
jnk cascade GO:0007254 80 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
regulation of transferase activity GO:0051338 355 0.023
positive regulation of hydrolase activity GO:0051345 331 0.023
cytoplasmic transport GO:0016482 379 0.023
embryo development GO:0009790 123 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
segmentation GO:0035282 4 0.022
regulation of peptidase activity GO:0052547 180 0.022
ncrna metabolic process GO:0034660 108 0.022
regulation of protein kinase activity GO:0045859 289 0.022
positive regulation of proteolysis GO:0045862 142 0.022
ion homeostasis GO:0050801 230 0.022
mitotic dna damage checkpoint GO:0044773 28 0.022
positive regulation of transferase activity GO:0051347 227 0.022
monocarboxylic acid biosynthetic process GO:0072330 67 0.022
intrinsic apoptotic signaling pathway GO:0097193 127 0.022
tachykinin receptor signaling pathway GO:0007217 3 0.022
regulation of cell differentiation GO:0045595 393 0.021
negative regulation of intracellular signal transduction GO:1902532 183 0.021
immune effector process GO:0002252 159 0.021
negative regulation of protein modification process GO:0031400 200 0.021
apoptotic signaling pathway GO:0097190 268 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.020
regulation of response to external stimulus GO:0032101 222 0.020
secretion by cell GO:0032940 226 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.020
response to lipid GO:0033993 206 0.020
protein stabilization GO:0050821 64 0.020
system process GO:0003008 349 0.020
negative regulation of transferase activity GO:0051348 124 0.020
lipid metabolic process GO:0006629 381 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
protein maturation GO:0051604 233 0.019
ventral spinal cord development GO:0021517 1 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.019
single organism cellular localization GO:1902580 332 0.019
positive regulation of cell proliferation GO:0008284 301 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
translation GO:0006412 132 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
cell development GO:0048468 328 0.018
dephosphorylation GO:0016311 209 0.018
single organism reproductive process GO:0044702 98 0.018
oxidation reduction process GO:0055114 396 0.018
positive regulation of cell death GO:0010942 263 0.018
negative regulation of protein maturation GO:1903318 142 0.018
circulatory system development GO:0072359 262 0.018
multicellular organismal aging GO:0010259 3 0.018
mitotic dna integrity checkpoint GO:0044774 30 0.017
growth GO:0040007 202 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
spinal cord development GO:0021510 4 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
defense response to virus GO:0051607 71 0.017
regulation of multi organism process GO:0043900 157 0.016
neuroblast proliferation GO:0007405 4 0.016
secretion GO:0046903 254 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
response to metal ion GO:0010038 84 0.016
organelle fission GO:0048285 149 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
regulation of protein maturation GO:1903317 150 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
response to organic cyclic compound GO:0014070 204 0.015
negative regulation of kinase activity GO:0033673 106 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
regulation of protein processing GO:0070613 150 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
transmembrane transport GO:0055085 399 0.015
negative regulation of protein processing GO:0010955 142 0.015
stress activated mapk cascade GO:0051403 93 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
fibroblast proliferation GO:0048144 33 0.015
regulation of protein stability GO:0031647 87 0.015
positive regulation of transport GO:0051050 336 0.015
regulation of growth GO:0040008 165 0.015
negative regulation of proteolysis GO:0045861 132 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
rna interference GO:0016246 4 0.015
protein localization to organelle GO:0033365 280 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
regulation of response to dna damage stimulus GO:2001020 94 0.014
cellular response to external stimulus GO:0071496 111 0.014
lipid biosynthetic process GO:0008610 177 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
membrane organization GO:0061024 292 0.014
dna repair GO:0006281 198 0.014
response to radiation GO:0009314 151 0.014
positive regulation of catabolic process GO:0009896 310 0.014
protein targeting GO:0006605 187 0.014
stem cell differentiation GO:0048863 93 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
regulation of cell migration GO:0030334 289 0.014
cation homeostasis GO:0055080 189 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
vesicle mediated transport GO:0016192 371 0.014
endosomal transport GO:0016197 129 0.014
protein oligomerization GO:0051259 173 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
negative regulation of response to external stimulus GO:0032102 83 0.013
protein processing GO:0016485 226 0.013
cell division GO:0051301 168 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
stress activated protein kinase signaling cascade GO:0031098 94 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
mrna metabolic process GO:0016071 175 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
dna integrity checkpoint GO:0031570 71 0.013
protein homooligomerization GO:0051260 100 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
cellular response to lipid GO:0071396 127 0.013
negative regulation of organelle organization GO:0010639 126 0.013
nucleoside triphosphate metabolic process GO:0009141 422 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
response to inorganic substance GO:0010035 127 0.013
oocyte development GO:0048599 1 0.013
response to extracellular stimulus GO:0009991 85 0.013
intracellular protein transport GO:0006886 270 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
cell differentiation in spinal cord GO:0021515 1 0.013
activation of protein kinase activity GO:0032147 90 0.013
positive regulation of immune response GO:0050778 159 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
negative regulation of multi organism process GO:0043901 92 0.012
respiratory gaseous exchange GO:0007585 3 0.012
regulation of map kinase activity GO:0043405 108 0.012
regulation of fibroblast proliferation GO:0048145 32 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
l amino acid import GO:0043092 4 0.012
cellular component morphogenesis GO:0032989 314 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
cell morphogenesis GO:0000902 296 0.012
cellular response to nutrient levels GO:0031669 69 0.012
negative regulation of growth GO:0045926 97 0.012
positive regulation of secretion GO:0051047 116 0.012
muscle structure development GO:0061061 98 0.012
viral life cycle GO:0019058 132 0.012
small molecule biosynthetic process GO:0044283 157 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
peptide transport GO:0015833 74 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
wnt signaling pathway GO:0016055 156 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
lipoprotein metabolic process GO:0042157 42 0.011
response to nutrient levels GO:0031667 81 0.011
single organism cell adhesion GO:0098602 179 0.011
ribonucleoprotein complex assembly GO:0022618 78 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
rna catabolic process GO:0006401 71 0.011
hormone transport GO:0009914 68 0.011
regulation of intracellular transport GO:0032386 195 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
regulation of hormone levels GO:0010817 125 0.011
rho protein signal transduction GO:0007266 26 0.011
reproductive structure development GO:0048608 55 0.011
ras protein signal transduction GO:0007265 73 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
regulation of immune effector process GO:0002697 91 0.011
organic acid biosynthetic process GO:0016053 97 0.011
somatic muscle development GO:0007525 1 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
oocyte differentiation GO:0009994 2 0.011
cell growth GO:0016049 160 0.011
cytokine production GO:0001816 247 0.010
positive regulation of immune system process GO:0002684 283 0.010
regulation of immune response GO:0050776 201 0.010
associative learning GO:0008306 1 0.010
signal release GO:0023061 70 0.010
purine containing compound catabolic process GO:0072523 411 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
negative regulation of immune system process GO:0002683 136 0.010
regulation of cytokine production GO:0001817 232 0.010
leukocyte activation GO:0045321 164 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
gtp catabolic process GO:0006184 237 0.010
regulation of gtpase activity GO:0043087 180 0.010
regulation of neurotransmitter secretion GO:0046928 3 0.010
nervous system development GO:0007399 293 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
regulation of stress activated mapk cascade GO:0032872 84 0.010

PMF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.045
muscular disease DOID:0080000 114 0.029
myopathy DOID:423 104 0.022
muscle tissue disease DOID:66 113 0.022
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
nervous system disease DOID:863 431 0.021
eye disease DOID:5614 149 0.021
central nervous system disease DOID:331 186 0.015
brain disease DOID:936 73 0.015
heart disease DOID:114 68 0.012
cardiomyopathy DOID:0050700 50 0.012
dilated cardiomyopathy DOID:12930 32 0.012
intrinsic cardiomyopathy DOID:0060036 50 0.012
cardiovascular system disease DOID:1287 106 0.012
disease of cellular proliferation DOID:14566 174 0.010
retinal disease DOID:5679 118 0.010