Homo sapiens

8 known processes

TPI1

triosephosphate isomerase 1

(Aliases: MGC88108,TPI)

TPI1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycolytic process GO:0006096 17 0.997
Fly
monocarboxylic acid metabolic process GO:0032787 185 0.994
Fly
oxidation reduction process GO:0055114 396 0.990
single organism carbohydrate metabolic process GO:0044723 193 0.975
Mouse Fly
pyruvate metabolic process GO:0006090 26 0.975
Fly
single organism carbohydrate catabolic process GO:0044724 33 0.970
Fly
muscle cell cellular homeostasis GO:0046716 3 0.935
nucleotide biosynthetic process GO:0009165 109 0.933
carbohydrate catabolic process GO:0016052 36 0.929
Fly
carbohydrate derivative biosynthetic process GO:1901137 207 0.921
generation of precursor metabolites and energy GO:0006091 68 0.917
Fly
carbohydrate metabolic process GO:0005975 207 0.914
Mouse Fly
ribose phosphate biosynthetic process GO:0046390 82 0.900
oxidoreduction coenzyme metabolic process GO:0006733 19 0.753
purine containing compound biosynthetic process GO:0072522 88 0.735
ribonucleotide biosynthetic process GO:0009260 81 0.681
nucleoside phosphate biosynthetic process GO:1901293 109 0.671
hexose metabolic process GO:0019318 55 0.617
Mouse
purine ribonucleotide biosynthetic process GO:0009152 79 0.557
purine ribonucleoside monophosphate biosynthetic process GO:0009168 16 0.468
cellular response to extracellular stimulus GO:0031668 72 0.458
purine ribonucleoside triphosphate biosynthetic process GO:0009206 11 0.425
mitotic cell cycle phase transition GO:0044772 162 0.384
cellular response to dna damage stimulus GO:0006974 379 0.351
post embryonic development GO:0009791 2 0.326
purine nucleotide biosynthetic process GO:0006164 84 0.317
muscle system process GO:0003012 81 0.308
atp biosynthetic process GO:0006754 11 0.303
cellular carbohydrate metabolic process GO:0044262 84 0.301
muscle contraction GO:0006936 73 0.292
ribonucleoside monophosphate metabolic process GO:0009161 187 0.289
pyridine nucleotide metabolic process GO:0019362 14 0.267
purine ribonucleoside biosynthetic process GO:0046129 23 0.263
striated muscle contraction GO:0006941 52 0.260
anatomical structure formation involved in morphogenesis GO:0048646 284 0.245
Worm Fly
glycosyl compound biosynthetic process GO:1901659 27 0.244
regulation of glucose metabolic process GO:0010906 28 0.243
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.239
multicellular organismal aging GO:0010259 3 0.234
Worm Fly
ribonucleoside biosynthetic process GO:0042455 25 0.225
regulation of cell cycle GO:0051726 393 0.223
purine nucleoside triphosphate metabolic process GO:0009144 412 0.216
purine nucleoside triphosphate biosynthetic process GO:0009145 11 0.211
regulation of generation of precursor metabolites and energy GO:0043467 27 0.210
anion transport GO:0006820 161 0.205
organonitrogen compound biosynthetic process GO:1901566 200 0.202
determination of adult lifespan GO:0008340 2 0.200
Worm Fly
cellular homeostasis GO:0019725 196 0.186
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.183
calcium ion transport GO:0006816 147 0.151
cofactor metabolic process GO:0051186 87 0.150
nucleoside triphosphate biosynthetic process GO:0009142 20 0.146
nicotinamide nucleotide metabolic process GO:0046496 14 0.141
response to hormone GO:0009725 175 0.136
monosaccharide metabolic process GO:0005996 74 0.135
Mouse
regulation of cell cycle process GO:0010564 266 0.135
cellular amide metabolic process GO:0043603 69 0.127
epithelial cell differentiation GO:0030855 141 0.123
striated muscle cell differentiation GO:0051146 43 0.121
Worm Fly
atp metabolic process GO:0046034 176 0.116
negative regulation of catalytic activity GO:0043086 335 0.105
myoblast fusion GO:0007520 1 0.101
Fly
organophosphate biosynthetic process GO:0090407 163 0.094
fatty acid metabolic process GO:0006631 115 0.086
cellular response to external stimulus GO:0071496 111 0.080
regulation of coenzyme metabolic process GO:0051196 3 0.077
dna integrity checkpoint GO:0031570 71 0.074
regulation of mitotic cell cycle phase transition GO:1901990 118 0.074
positive regulation of cellular amine metabolic process GO:0033240 7 0.071
nadp metabolic process GO:0006739 10 0.068
purine nucleoside monophosphate biosynthetic process GO:0009127 16 0.063
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.063
cation transmembrane transport GO:0098655 238 0.062
glucan metabolic process GO:0044042 22 0.061
unsaturated fatty acid biosynthetic process GO:0006636 21 0.060
regulation of nucleotide metabolic process GO:0006140 269 0.059
formation of primary germ layer GO:0001704 42 0.059
nucleoside triphosphate metabolic process GO:0009141 422 0.058
cell cycle phase transition GO:0044770 173 0.057
positive regulation of transport GO:0051050 336 0.055
striated muscle cell development GO:0055002 27 0.055
Worm
chordate embryonic development GO:0043009 34 0.055
mitotic cell cycle checkpoint GO:0007093 68 0.054
anatomical structure homeostasis GO:0060249 100 0.053
negative regulation of cell cycle GO:0045786 193 0.052
epithelium development GO:0060429 227 0.051
glomerular mesangial cell development GO:0072144 1 0.048
pyridine containing compound metabolic process GO:0072524 18 0.047
somitogenesis GO:0001756 2 0.047
g2 dna damage checkpoint GO:0031572 26 0.047
purine nucleoside biosynthetic process GO:0042451 23 0.045
positive regulation of phosphorylation GO:0042327 394 0.044
response to biotic stimulus GO:0009607 276 0.044
cellular macromolecule catabolic process GO:0044265 380 0.044
response to hypoxia GO:0001666 96 0.043
response to external biotic stimulus GO:0043207 261 0.042
mitotic cell cycle GO:0000278 326 0.042
regulation of glycolytic process GO:0006110 10 0.042
response to abiotic stimulus GO:0009628 336 0.041
Fly
spermatid development GO:0007286 4 0.041
myosin filament organization GO:0031033 2 0.041
Worm
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
negative regulation of mitotic cell cycle GO:0045930 102 0.039
striated muscle myosin thick filament assembly GO:0071688 2 0.039
Worm
response to other organism GO:0051707 261 0.038
cation transport GO:0006812 331 0.038
sulfur compound metabolic process GO:0006790 101 0.037
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.037
erythrocyte homeostasis GO:0034101 31 0.036
peptidyl serine modification GO:0018209 106 0.036
microtubule based process GO:0007017 210 0.035
ribonucleoside triphosphate metabolic process GO:0009199 412 0.034
nucleoside biosynthetic process GO:0009163 26 0.034
regulation of cofactor metabolic process GO:0051193 3 0.034
dephosphorylation GO:0016311 209 0.034
negative regulation of cell cycle process GO:0010948 121 0.034
mitotic cell cycle process GO:1903047 286 0.032
cell cycle checkpoint GO:0000075 117 0.031
protein homooligomerization GO:0051260 100 0.031
positive regulation of catabolic process GO:0009896 310 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
vitamin metabolic process GO:0006766 26 0.030
protein localization to organelle GO:0033365 280 0.030
respiratory burst GO:0045730 12 0.030
response to virus GO:0009615 126 0.027
negative regulation of ion transport GO:0043271 39 0.027
receptor mediated endocytosis GO:0006898 84 0.027
regulation of cellular amine metabolic process GO:0033238 11 0.027
negative regulation of homeostatic process GO:0032845 59 0.026
amine metabolic process GO:0009308 44 0.026
cell growth GO:0016049 160 0.025
response to decreased oxygen levels GO:0036293 96 0.025
aging GO:0007568 66 0.025
Worm Fly
coenzyme catabolic process GO:0009109 5 0.025
segmentation GO:0035282 4 0.025
cellular amino acid metabolic process GO:0006520 116 0.024
response to oxygen containing compound GO:1901700 369 0.024
positive regulation of developmental process GO:0051094 314 0.024
behavior GO:0007610 112 0.024
embryo development ending in birth or egg hatching GO:0009792 34 0.024
chemical homeostasis GO:0048878 306 0.024
carbohydrate phosphorylation GO:0046835 17 0.024
regulation of peptidase activity GO:0052547 180 0.023
ribonucleoside monophosphate biosynthetic process GO:0009156 17 0.023
alpha amino acid metabolic process GO:1901605 72 0.023
regulation of fibroblast proliferation GO:0048145 32 0.023
cell aging GO:0007569 52 0.022
lipid storage GO:0019915 28 0.022
fructose 1 6 bisphosphate metabolic process GO:0030388 5 0.022
cell projection organization GO:0030030 252 0.022
developmental growth GO:0048589 48 0.022
secretion GO:0046903 254 0.022
regulation of cellular response to stress GO:0080135 244 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
regulation of carbohydrate catabolic process GO:0043470 11 0.021
cofactor catabolic process GO:0051187 7 0.021
regulation of mapk cascade GO:0043408 262 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.020
response to radiation GO:0009314 151 0.020
regulation of growth GO:0040008 165 0.020
metal ion transport GO:0030001 272 0.019
tissue homeostasis GO:0001894 63 0.019
carbohydrate homeostasis GO:0033500 31 0.019
cellular respiration GO:0045333 21 0.019
cellular lipid metabolic process GO:0044255 303 0.019
response to extracellular stimulus GO:0009991 85 0.019
homeostasis of number of cells GO:0048872 40 0.018
maintenance of location GO:0051235 112 0.018
cellular modified amino acid metabolic process GO:0006575 64 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
reproductive process GO:0022414 106 0.018
regulation of secondary metabolic process GO:0043455 2 0.018
myeloid cell homeostasis GO:0002262 34 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.017
cell development GO:0048468 328 0.017
Worm
replicative cell aging GO:0001302 3 0.017
cellular carbohydrate catabolic process GO:0044275 17 0.016
carboxylic acid transport GO:0046942 63 0.016
cellular response to hormone stimulus GO:0032870 125 0.016
cellular amine metabolic process GO:0044106 41 0.016
cyclic purine nucleotide metabolic process GO:0052652 60 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
growth GO:0040007 202 0.016
nucleoside monophosphate metabolic process GO:0009123 191 0.016
cellular ion homeostasis GO:0006873 168 0.016
taxis GO:0042330 157 0.015
endocytosis GO:0006897 159 0.015
regulation of binding GO:0051098 111 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
mitotic dna integrity checkpoint GO:0044774 30 0.015
transmembrane transport GO:0055085 399 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
regulation of protein secretion GO:0050708 86 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.015
cellular chemical homeostasis GO:0055082 180 0.014
mitotic g2 dna damage checkpoint GO:0007095 7 0.014
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
defense response GO:0006952 315 0.014
positive regulation of protein secretion GO:0050714 60 0.014
positive regulation of growth GO:0045927 58 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
mitochondrion organization GO:0007005 156 0.013
digestive system development GO:0055123 75 0.013
renal interstitial fibroblast development GO:0072141 1 0.013
sex differentiation GO:0007548 45 0.013
system process GO:0003008 349 0.013
Fly
reproduction GO:0000003 63 0.013
organic acid biosynthetic process GO:0016053 97 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
nucleoside monophosphate biosynthetic process GO:0009124 19 0.013
cellular response to lipid GO:0071396 127 0.013
cell part morphogenesis GO:0032990 137 0.012
regeneration GO:0031099 4 0.012
pentose phosphate shunt GO:0006098 5 0.012
regulation of protein localization GO:0032880 296 0.012
glucose homeostasis GO:0042593 31 0.012
regulation of secretion by cell GO:1903530 177 0.012
prostaglandin metabolic process GO:0006693 17 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.012
small molecule catabolic process GO:0044282 92 0.012
neural nucleus development GO:0048857 47 0.012
female gamete generation GO:0007292 2 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
cellular carbohydrate biosynthetic process GO:0034637 21 0.011
ribonucleoprotein complex biogenesis GO:0022613 116 0.011
cytoplasmic transport GO:0016482 379 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
cytokine production GO:0001816 247 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of cell shape GO:0008360 48 0.011
sequestering of calcium ion GO:0051208 17 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
positive regulation of protein transport GO:0051222 135 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
regulation of kinase activity GO:0043549 314 0.011
response to metal ion GO:0010038 84 0.011
positive regulation of proteolysis GO:0045862 142 0.010
gonad development GO:0008406 34 0.010
regulation of carbohydrate metabolic process GO:0006109 54 0.010
multicellular organismal reproductive process GO:0048609 40 0.010
fructose metabolic process GO:0006000 3 0.010
positive regulation of cell cycle GO:0045787 140 0.010
protein kinase a signaling GO:0010737 9 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of cell activation GO:0050865 125 0.010
nuclear import GO:0051170 106 0.010

TPI1 disease predictions

Disease DO term ID Size Probability Func Analog Org
hemolytic anemia DOID:583 20 0.892
immune system disease DOID:2914 155 0.892
normocytic anemia DOID:720 20 0.892
anemia DOID:2355 55 0.892
hematopoietic system disease DOID:74 100 0.892
congenital hemolytic anemia DOID:589 9 0.674
musculoskeletal system disease DOID:17 223 0.016
disease of metabolism DOID:0014667 295 0.009
acquired metabolic disease DOID:0060158 58 0.002
carbohydrate metabolism disease DOID:0050013 32 0.001
glucose metabolism disease DOID:4194 32 0.001