Homo sapiens

0 known processes

PPIL4

peptidylprolyl isomerase (cyclophilin)-like 4

(Aliases: HDCME13P)

PPIL4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amine metabolic process GO:0033238 11 0.196
cellular amino acid metabolic process GO:0006520 116 0.188
amine metabolic process GO:0009308 44 0.156
regulation of cellular ketone metabolic process GO:0010565 50 0.152
cellular ketone metabolic process GO:0042180 80 0.143
regulation of cellular amino acid metabolic process GO:0006521 6 0.143
negative regulation of cellular amine metabolic process GO:0033239 3 0.135
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.127
protein localization to organelle GO:0033365 280 0.108
mitotic cell cycle process GO:1903047 286 0.104
protein modification by small protein conjugation GO:0032446 342 0.100
cellular amine metabolic process GO:0044106 41 0.085
posttranscriptional regulation of gene expression GO:0010608 213 0.070
cellular potassium ion transport GO:0071804 60 0.068
negative regulation of protein metabolic process GO:0051248 391 0.067
cation transport GO:0006812 331 0.059
nuclear transport GO:0051169 179 0.059
otic vesicle development GO:0071599 1 0.058
endodermal cell fate commitment GO:0001711 4 0.057
protein ubiquitination GO:0016567 314 0.057
cytoplasmic transport GO:0016482 379 0.057
regulation of cell cycle process GO:0010564 266 0.051
regulation of cellular component biogenesis GO:0044087 281 0.049
stem cell division GO:0017145 2 0.049
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.048
cellular lipid metabolic process GO:0044255 303 0.048
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 2 0.048
determination of dorsal ventral asymmetry GO:0048262 4 0.048
actin filament based process GO:0030029 224 0.047
regulation of proteolysis GO:0030162 293 0.047
negative regulation of cellular component organization GO:0051129 235 0.044
neuromuscular junction development GO:0007528 3 0.043
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.042
blastoderm segmentation GO:0007350 2 0.041
positive regulation of cytoplasmic transport GO:1903651 82 0.041
positive regulation of programmed cell death GO:0043068 249 0.040
positive regulation of cellular catabolic process GO:0031331 284 0.040
positive regulation of transport GO:0051050 336 0.040
embryonic morphogenesis GO:0048598 85 0.040
cell development GO:0048468 328 0.039
negative regulation of cell proliferation GO:0008285 228 0.038
mitotic cell cycle GO:0000278 326 0.038
interspecies interaction between organisms GO:0044419 156 0.038
cellular macromolecule catabolic process GO:0044265 380 0.037
positive regulation of hydrolase activity GO:0051345 331 0.036
hematopoietic or lymphoid organ development GO:0048534 186 0.036
negative regulation of protein modification process GO:0031400 200 0.036
maintenance of location GO:0051235 112 0.035
digestive system development GO:0055123 75 0.035
determination of adult lifespan GO:0008340 2 0.035
regulation of intracellular transport GO:0032386 195 0.035
post embryonic development GO:0009791 2 0.034
Worm
positive regulation of cellular component organization GO:0051130 376 0.034
regulation of cell differentiation GO:0045595 393 0.034
segmentation GO:0035282 4 0.034
positive regulation of cell differentiation GO:0045597 211 0.034
regulation of protein ubiquitination GO:0031396 95 0.033
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
regulation of homeostatic process GO:0032844 121 0.033
single organism cellular localization GO:1902580 332 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.032
rna processing GO:0006396 255 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
endocytosis GO:0006897 159 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
viral process GO:0016032 146 0.031
positive regulation of developmental process GO:0051094 314 0.030
ribonucleoprotein complex biogenesis GO:0022613 116 0.030
modification dependent macromolecule catabolic process GO:0043632 212 0.030
multi organism cellular process GO:0044764 156 0.029
ectodermal placode formation GO:0060788 1 0.029
convergent extension involved in gastrulation GO:0060027 1 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
mitotic cell cycle phase transition GO:0044772 162 0.029
neurogenesis GO:0022008 169 0.028
Fly
protein catabolic process GO:0030163 325 0.027
negative regulation of phosphate metabolic process GO:0045936 267 0.027
multicellular organismal aging GO:0010259 3 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
lipid metabolic process GO:0006629 381 0.027
female gamete generation GO:0007292 2 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
cell cycle phase transition GO:0044770 173 0.027
response to oxygen containing compound GO:1901700 369 0.026
endosomal transport GO:0016197 129 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.026
receptor metabolic process GO:0043112 81 0.025
regulation of mitotic cell cycle phase transition GO:1901990 118 0.025
regulation of transferase activity GO:0051338 355 0.024
modification dependent protein catabolic process GO:0019941 209 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regeneration GO:0031099 4 0.024
inner ear morphogenesis GO:0042472 4 0.024
positive regulation of proteolysis GO:0045862 142 0.024
negative regulation of cell death GO:0060548 345 0.024
regulation of protein complex assembly GO:0043254 147 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
chromatin modification GO:0016568 298 0.023
positive regulation of catabolic process GO:0009896 310 0.023
positive regulation of cell death GO:0010942 263 0.023
regulation of ion homeostasis GO:2000021 73 0.023
chromatin organization GO:0006325 351 0.023
actin cytoskeleton organization GO:0030036 207 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
cofactor metabolic process GO:0051186 87 0.023
regulation of cell cycle GO:0051726 393 0.023
late endosome to vacuole transport GO:0045324 2 0.022
receptor catabolic process GO:0032801 11 0.022
positive regulation of mapk cascade GO:0043410 190 0.022
inorganic ion transmembrane transport GO:0098660 231 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.022
cell cycle g1 s phase transition GO:0044843 80 0.022
digestive tract development GO:0048565 75 0.022
intracellular protein transport GO:0006886 270 0.022
regulation of pathway restricted smad protein phosphorylation GO:0060393 34 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
regulation of protein catabolic process GO:0042176 155 0.022
locomotory behavior GO:0007626 1 0.021
cation transmembrane transport GO:0098655 238 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
polyprenol metabolic process GO:0016093 3 0.021
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
regulation of cell cycle phase transition GO:1901987 126 0.021
potassium ion transmembrane transport GO:0071805 60 0.021
regulation of cellular component size GO:0032535 82 0.021
alcohol metabolic process GO:0006066 114 0.021
gastrulation with mouth forming second GO:0001702 1 0.021
cell migration involved in gastrulation GO:0042074 1 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
negative regulation of developmental process GO:0051093 247 0.020
nitrogen compound transport GO:0071705 191 0.020
negative regulation of cell cycle process GO:0010948 121 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
positive regulation of osteoblast differentiation GO:0045669 23 0.020
defense response GO:0006952 315 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
digestive tract morphogenesis GO:0048546 56 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
regulation of kinase activity GO:0043549 314 0.020
monovalent inorganic cation transport GO:0015672 128 0.019
oogenesis GO:0048477 2 0.019
coenzyme metabolic process GO:0006732 65 0.019
system process GO:0003008 349 0.019
covalent chromatin modification GO:0016569 254 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
histone modification GO:0016570 251 0.019
convergent extension GO:0060026 1 0.019
protein processing GO:0016485 226 0.019
dephosphorylation GO:0016311 209 0.019
biological adhesion GO:0022610 331 0.019
regulation of response to external stimulus GO:0032101 222 0.019
metal ion transport GO:0030001 272 0.019
response to growth factor GO:0070848 205 0.019
regulation of cellular component movement GO:0051270 334 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
ion transmembrane transport GO:0034220 338 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
regulation of protein localization GO:0032880 296 0.018
circulatory system development GO:0072359 262 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
growth GO:0040007 202 0.018
Worm
hemopoiesis GO:0030097 180 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
g1 s transition of mitotic cell cycle GO:0000082 78 0.018
response to biotic stimulus GO:0009607 276 0.018
immune system development GO:0002520 195 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
negative regulation of transferase activity GO:0051348 124 0.017
transmembrane transport GO:0055085 399 0.017
lysosomal transport GO:0007041 33 0.017
cellular component morphogenesis GO:0032989 314 0.017
negative regulation of immune system process GO:0002683 136 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
vesicle mediated transport GO:0016192 371 0.017
purine ribonucleoside metabolic process GO:0046128 437 0.017
cell division GO:0051301 168 0.017
cellular protein complex assembly GO:0043623 188 0.017
response to other organism GO:0051707 261 0.017
peptidyl serine modification GO:0018209 106 0.017
nervous system development GO:0007399 293 0.017
Fly
protein stabilization GO:0050821 64 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
epithelium development GO:0060429 227 0.017
heart morphogenesis GO:0003007 48 0.017
wnt signaling pathway GO:0016055 156 0.017
endodermal cell fate specification GO:0001714 4 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
negative regulation of cell growth GO:0030308 83 0.016
somatic stem cell maintenance GO:0035019 4 0.016
cell proliferation involved in heart valve development GO:2000793 1 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
chromatin assembly or disassembly GO:0006333 78 0.016
rna splicing GO:0008380 131 0.016
cytokine production GO:0001816 247 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 1 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
potassium ion transport GO:0006813 62 0.016
regulation of ossification GO:0030278 58 0.016
purine containing compound catabolic process GO:0072523 411 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
negative regulation of growth GO:0045926 97 0.015
response to inorganic substance GO:0010035 127 0.015
apoptotic signaling pathway GO:0097190 268 0.015
protein targeting GO:0006605 187 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
cell projection organization GO:0030030 252 0.015
endodermal cell differentiation GO:0035987 31 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.015
nucleotide catabolic process GO:0009166 408 0.015
neurotransmitter secretion GO:0007269 4 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.015
positive regulation of meiotic cell cycle GO:0051446 2 0.015
organelle assembly GO:0070925 176 0.015
chemical homeostasis GO:0048878 306 0.015
cell morphogenesis GO:0000902 296 0.014
nucleoside catabolic process GO:0009164 408 0.014
regulation of cell growth GO:0001558 135 0.014
tube morphogenesis GO:0035239 95 0.014
regulation of secretion by cell GO:1903530 177 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
autophagy GO:0006914 88 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
regulation of peptidase activity GO:0052547 180 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
ectodermal placode morphogenesis GO:0071697 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 98 0.014
endochondral bone morphogenesis GO:0060350 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
positive regulation of endopeptidase activity GO:0010950 84 0.014
ion homeostasis GO:0050801 230 0.014
stem cell differentiation GO:0048863 93 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
regulation of canonical wnt signaling pathway GO:0060828 88 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
peptidyl lysine modification GO:0018205 144 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
regulation of anatomical structure size GO:0090066 101 0.014
ribosomal subunit export from nucleus GO:0000054 4 0.014
nuclear export GO:0051168 69 0.013
cell growth GO:0016049 160 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
sequestering of calcium ion GO:0051208 17 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
receptor mediated endocytosis GO:0006898 84 0.013
mrna metabolic process GO:0016071 175 0.013
regulation of growth GO:0040008 165 0.013
response to abiotic stimulus GO:0009628 336 0.013
fatty acid metabolic process GO:0006631 115 0.013
single organism membrane organization GO:0044802 268 0.013
organophosphate catabolic process GO:0046434 430 0.013
protein maturation GO:0051604 233 0.013
response to lipid GO:0033993 206 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
cell adhesion GO:0007155 325 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
maintenance of protein location in cell GO:0032507 56 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
single organism cell adhesion GO:0098602 179 0.013
receptor internalization GO:0031623 43 0.013
calcium ion homeostasis GO:0055074 122 0.013
mapk cascade GO:0000165 288 0.013
response to external biotic stimulus GO:0043207 261 0.013
progesterone receptor signaling pathway GO:0050847 3 0.013
vacuolar transport GO:0007034 34 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
immune response GO:0006955 307 0.012
regulation of ligase activity GO:0051340 29 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
regulation of neuron differentiation GO:0045664 70 0.012
positive regulation of cellular component movement GO:0051272 181 0.012
regulation of cell activation GO:0050865 125 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.012
trna export from nucleus GO:0006409 1 0.012
nuclear division GO:0000280 128 0.012
heart development GO:0007507 95 0.012
regulation of protein stability GO:0031647 87 0.012
cellular homeostasis GO:0019725 196 0.012
sequestering of metal ion GO:0051238 24 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
metal ion homeostasis GO:0055065 169 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
regulation of mrna export from nucleus GO:0010793 3 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.012
response to organic cyclic compound GO:0014070 204 0.012
memory GO:0007613 3 0.012
connective tissue development GO:0061448 39 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
reproductive process GO:0022414 106 0.011
Worm
cellular response to dna damage stimulus GO:0006974 379 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
skeletal system development GO:0001501 79 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
response to wounding GO:0009611 168 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
negative regulation of alpha beta t cell activation GO:0046636 3 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.011
response to virus GO:0009615 126 0.011
gastrulation GO:0007369 51 0.011
protein monoubiquitination GO:0006513 39 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
response to cytokine GO:0034097 232 0.011
regulation of mapk cascade GO:0043408 262 0.011
muscle system process GO:0003012 81 0.011
embryo development GO:0009790 123 0.011
Worm
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.011
tissue regeneration GO:0042246 3 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
protein oligomerization GO:0051259 173 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
isoprenoid metabolic process GO:0006720 39 0.011
response to nitrogen compound GO:1901698 184 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
positive regulation of immune response GO:0050778 159 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
positive regulation of ossification GO:0045778 32 0.011
positive regulation of nervous system development GO:0051962 54 0.011
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.011
membrane organization GO:0061024 292 0.010
single organism reproductive process GO:0044702 98 0.010
Worm
ribonucleoprotein complex localization GO:0071166 4 0.010
regulation of multi organism process GO:0043900 157 0.010
rna interference GO:0016246 4 0.010
positive regulation of nucleotide metabolic process GO:0045981 230 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
regulation of lymphocyte activation GO:0051249 103 0.010
negative regulation of cell cycle GO:0045786 193 0.010
translation GO:0006412 132 0.010
response to metal ion GO:0010038 84 0.010
lipid biosynthetic process GO:0008610 177 0.010
regulation of protein kinase activity GO:0045859 289 0.010
fatty acid biosynthetic process GO:0006633 46 0.010
formation of primary germ layer GO:0001704 42 0.010
ossification GO:0001503 121 0.010

PPIL4 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.117
eye and adnexa disease DOID:1492 150 0.117
nervous system disease DOID:863 431 0.117
eye disease DOID:5614 149 0.117
retinal disease DOID:5679 118 0.021
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
retinal degeneration DOID:8466 89 0.013
musculoskeletal system disease DOID:17 223 0.012