Homo sapiens

54 known processes

PRMT5

protein arginine methyltransferase 5

(Aliases: HRMT1L5,JBP1,SKB1Hs,IBP72,SKB1)

PRMT5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.982
chromatin organization GO:0006325 351 0.969
Mouse Worm
protein alkylation GO:0008213 74 0.968
ribonucleoprotein complex biogenesis GO:0022613 116 0.966
cellular macromolecular complex assembly GO:0034622 324 0.957
histone arginine methylation GO:0034969 6 0.912
Mouse Worm
mrna metabolic process GO:0016071 175 0.904
chromatin modification GO:0016568 298 0.886
Mouse Worm
ribonucleoprotein complex assembly GO:0022618 78 0.865
mitotic cell cycle GO:0000278 326 0.846
methylation GO:0032259 106 0.789
mrna processing GO:0006397 133 0.776
nucleocytoplasmic transport GO:0006913 176 0.765
macromolecule methylation GO:0043414 97 0.725
protein methylation GO:0006479 74 0.716
anterior posterior axis specification embryo GO:0008595 2 0.711
Fly
mitotic nuclear division GO:0007067 119 0.707
spliceosomal snrnp assembly GO:0000387 28 0.661
oocyte development GO:0048599 1 0.554
Fly
cell development GO:0048468 328 0.532
Fly
oocyte differentiation GO:0009994 2 0.508
Fly
embryo development GO:0009790 123 0.489
Worm Fly
reproductive system development GO:0061458 56 0.465
ribonucleoprotein complex subunit organization GO:0071826 81 0.449
rna processing GO:0006396 255 0.432
microtubule based process GO:0007017 210 0.422
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.341
single organism cellular localization GO:1902580 332 0.334
histone modification GO:0016570 251 0.333
Mouse Worm
spindle organization GO:0007051 53 0.315
covalent chromatin modification GO:0016569 254 0.293
Mouse Worm
mitotic cell cycle process GO:1903047 286 0.291
female gamete generation GO:0007292 2 0.275
Fly
organelle assembly GO:0070925 176 0.233
microtubule cytoskeleton organization GO:0000226 176 0.224
reproductive structure development GO:0048608 55 0.215
generation of neurons GO:0048699 152 0.170
oogenesis GO:0048477 2 0.157
Fly
gonad development GO:0008406 34 0.133
sex differentiation GO:0007548 45 0.123
single organism reproductive process GO:0044702 98 0.123
Fly
nuclear division GO:0000280 128 0.118
chromatin assembly or disassembly GO:0006333 78 0.116
reproduction GO:0000003 63 0.113
Fly
cellular macromolecule catabolic process GO:0044265 380 0.110
regulation of cell cycle process GO:0010564 266 0.104
amine metabolic process GO:0009308 44 0.102
cellular response to dna damage stimulus GO:0006974 379 0.099
Worm
anterior posterior axis specification GO:0009948 2 0.098
Fly
cellular component morphogenesis GO:0032989 314 0.094
reproductive process GO:0022414 106 0.092
Fly
embryo development ending in birth or egg hatching GO:0009792 34 0.091
Worm
cellular ketone metabolic process GO:0042180 80 0.086
rna splicing via transesterification reactions GO:0000375 90 0.086
mrna splicing via spliceosome GO:0000398 89 0.084
negative regulation of protein metabolic process GO:0051248 391 0.082
positive regulation of cell proliferation GO:0008284 301 0.081
developmental process involved in reproduction GO:0003006 66 0.080
Fly
histone h4 r3 methylation GO:0043985 3 0.078
Mouse Worm
cellular component assembly involved in morphogenesis GO:0010927 73 0.077
neuron differentiation GO:0030182 138 0.076
determination of adult lifespan GO:0008340 2 0.072
protein targeting to nucleus GO:0044744 104 0.072
positive regulation of developmental process GO:0051094 314 0.072
regulation of gene expression epigenetic GO:0040029 73 0.072
cardiovascular system development GO:0072358 262 0.070
mapk cascade GO:0000165 288 0.070
negative regulation of cellular protein metabolic process GO:0032269 353 0.068
ras protein signal transduction GO:0007265 73 0.067
nuclear transport GO:0051169 179 0.065
cellular amino acid metabolic process GO:0006520 116 0.064
cell type specific apoptotic process GO:0097285 125 0.064
ncrna metabolic process GO:0034660 108 0.063
blastoderm segmentation GO:0007350 2 0.062
Fly
protein import GO:0017038 130 0.059
neuron projection development GO:0031175 106 0.059
translation GO:0006412 132 0.057
single organism nuclear import GO:1902593 104 0.057
growth GO:0040007 202 0.057
Fly
mitotic spindle organization GO:0007052 27 0.054
small gtpase mediated signal transduction GO:0007264 78 0.054
anatomical structure formation involved in morphogenesis GO:0048646 284 0.054
segmentation GO:0035282 4 0.052
Fly
regulation of dna metabolic process GO:0051052 153 0.048
regulation of cell differentiation GO:0045595 393 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
organelle fission GO:0048285 149 0.045
nervous system development GO:0007399 293 0.042
multicellular organism reproduction GO:0032504 42 0.042
Fly
cell division GO:0051301 168 0.042
ribonucleoside monophosphate metabolic process GO:0009161 187 0.041
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
regulation of growth GO:0040008 165 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.040
molting cycle GO:0042303 28 0.040
development of primary sexual characteristics GO:0045137 35 0.040
regulation of chromosome organization GO:0033044 103 0.039
cytoplasmic transport GO:0016482 379 0.037
regulation of mapk cascade GO:0043408 262 0.036
receptor mediated endocytosis GO:0006898 84 0.036
protein processing GO:0016485 226 0.036
establishment of protein localization to organelle GO:0072594 172 0.035
cell part morphogenesis GO:0032990 137 0.034
cellular protein complex assembly GO:0043623 188 0.034
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.033
Mouse
nuclear import GO:0051170 106 0.032
cellular amine metabolic process GO:0044106 41 0.031
regulation of translation GO:0006417 89 0.031
signal transduction by phosphorylation GO:0023014 297 0.030
establishment of organelle localization GO:0051656 59 0.030
chordate embryonic development GO:0043009 34 0.028
nucleus localization GO:0051647 1 0.028
protein import into nucleus GO:0006606 104 0.028
negative regulation of cell cycle GO:0045786 193 0.027
regulation of cell cycle GO:0051726 393 0.027
sexual reproduction GO:0019953 37 0.027
Fly
protein maturation GO:0051604 233 0.026
positive regulation of hydrolase activity GO:0051345 331 0.026
neuron development GO:0048666 113 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
multi organism reproductive process GO:0044703 54 0.025
Fly
multicellular organismal aging GO:0010259 3 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
blastocyst development GO:0001824 3 0.023
cell projection organization GO:0030030 252 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
rna splicing GO:0008380 131 0.022
protein localization to nucleus GO:0034504 136 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
spindle assembly GO:0051225 29 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
atp metabolic process GO:0046034 176 0.021
endocytosis GO:0006897 159 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of proteolysis GO:0030162 293 0.020
regulation of cell growth GO:0001558 135 0.020
negative regulation of cellular component organization GO:0051129 235 0.019
actin cytoskeleton organization GO:0030036 207 0.019
cell cycle checkpoint GO:0000075 117 0.019
generation of precursor metabolites and energy GO:0006091 68 0.019
organelle localization GO:0051640 84 0.019
histone methylation GO:0016571 60 0.018
Mouse Worm
photoreceptor cell differentiation GO:0046530 2 0.018
regulation of cell division GO:0051302 116 0.018
positive regulation of growth GO:0045927 58 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
nucleoside phosphate biosynthetic process GO:1901293 109 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.017
regulation of protein import into nucleus GO:0042306 78 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
prostate gland development GO:0030850 3 0.017
secretion GO:0046903 254 0.017
regulation of rna splicing GO:0043484 62 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.016
negative regulation of protein modification process GO:0031400 200 0.016
circulatory system development GO:0072359 262 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
axon development GO:0061564 34 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
regionalization GO:0003002 29 0.016
Fly
regulation of intracellular transport GO:0032386 195 0.016
mitotic cell cycle phase transition GO:0044772 162 0.015
apoptotic signaling pathway GO:0097190 268 0.015
Worm
intracellular receptor signaling pathway GO:0030522 104 0.015
Fly
microtubule organizing center organization GO:0031023 62 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
nucleosome assembly GO:0006334 50 0.015
protein localization to organelle GO:0033365 280 0.014
intracellular protein transport GO:0006886 270 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
blood vessel morphogenesis GO:0048514 162 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
vesicle mediated transport GO:0016192 371 0.013
developmental growth GO:0048589 48 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
response to radiation GO:0009314 151 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
epithelium development GO:0060429 227 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
cellular protein catabolic process GO:0044257 261 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
regulation of protein transport GO:0051223 213 0.012
central nervous system development GO:0007417 123 0.012
cytokine production GO:0001816 247 0.012
positive regulation of cellular component organization GO:0051130 376 0.011
negative regulation of cell death GO:0060548 345 0.011
neurogenesis GO:0022008 169 0.011
immune system development GO:0002520 195 0.011
single organism membrane organization GO:0044802 268 0.011
cell morphogenesis GO:0000902 296 0.011
carbohydrate metabolic process GO:0005975 207 0.011
regulation of developmental growth GO:0048638 30 0.011
negative regulation of developmental process GO:0051093 247 0.011
ribosome biogenesis GO:0042254 48 0.011
negative regulation of cell cycle phase transition GO:1901988 89 0.011
organ morphogenesis GO:0009887 147 0.011
regulation of transferase activity GO:0051338 355 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
regulation of protein localization GO:0032880 296 0.011
regulation of centriole replication GO:0046599 7 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
purine nucleotide catabolic process GO:0006195 405 0.010
regulation of neurogenesis GO:0050767 82 0.010
regulation of protein processing GO:0070613 150 0.010
blood vessel development GO:0001568 172 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
regulation of spindle checkpoint GO:0090231 12 0.010
regulation of nucleocytoplasmic transport GO:0046822 98 0.010
embryonic morphogenesis GO:0048598 85 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
response to abiotic stimulus GO:0009628 336 0.010
regulation of mrna metabolic process GO:1903311 53 0.010

PRMT5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.018