Homo sapiens

37 known processes

STIL

SCL/TAL1 interrupting locus

(Aliases: DKFZp686O09161,MCPH7,SIL)

STIL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuroblast proliferation GO:0007405 4 0.852
microtubule organizing center organization GO:0031023 62 0.790
regulation of cell cycle process GO:0010564 266 0.727
Mouse
mitotic cell cycle GO:0000278 326 0.715
organelle fission GO:0048285 149 0.634
axoneme assembly GO:0035082 3 0.624
centrosome organization GO:0051297 58 0.600
centrosome duplication GO:0051298 28 0.589
mitotic cell cycle process GO:1903047 286 0.582
somatic stem cell division GO:0048103 1 0.510
microtubule cytoskeleton organization GO:0000226 176 0.504
mitotic nuclear division GO:0007067 119 0.502
nucleoside triphosphate catabolic process GO:0009143 394 0.484
organelle assembly GO:0070925 176 0.463
Zebrafish
cell division GO:0051301 168 0.450
microtubule based process GO:0007017 210 0.440
purine nucleoside catabolic process GO:0006152 398 0.436
nuclear division GO:0000280 128 0.385
ribonucleotide catabolic process GO:0009261 405 0.362
negative regulation of organelle organization GO:0010639 126 0.355
centrosome cycle GO:0007098 32 0.354
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.323
centriole replication GO:0007099 13 0.284
regulation of cell cycle GO:0051726 393 0.278
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.270
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.242
cilium assembly GO:0042384 63 0.242
nucleoside phosphate catabolic process GO:1901292 412 0.240
cellular protein complex assembly GO:0043623 188 0.220
nucleoside triphosphate metabolic process GO:0009141 422 0.207
ribonucleoside triphosphate catabolic process GO:0009203 391 0.198
ribonucleoside monophosphate catabolic process GO:0009158 158 0.173
neuroblast division GO:0055057 1 0.173
regulation of cell differentiation GO:0045595 393 0.170
centrosome separation GO:0051299 3 0.168
purine nucleotide catabolic process GO:0006195 405 0.165
male meiosis GO:0007140 1 0.155
cellular macromolecule catabolic process GO:0044265 380 0.152
dna repair GO:0006281 198 0.148
nucleoside monophosphate catabolic process GO:0009125 159 0.146
meiotic chromosome segregation GO:0045132 4 0.143
purine nucleoside monophosphate metabolic process GO:0009126 186 0.142
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.140
purine ribonucleoside catabolic process GO:0046130 398 0.140
centriole assembly GO:0098534 14 0.137
chromosome segregation GO:0007059 114 0.131
cell cycle phase transition GO:0044770 173 0.130
Mouse
regulation of cellular component biogenesis GO:0044087 281 0.127
microtubule polymerization GO:0046785 18 0.125
purine containing compound catabolic process GO:0072523 411 0.122
organophosphate catabolic process GO:0046434 430 0.120
regulation of mitotic sister chromatid segregation GO:0033047 27 0.116
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.114
regulation of cytoskeleton organization GO:0051493 177 0.108
negative regulation of cytoskeleton organization GO:0051494 45 0.108
cellular component disassembly GO:0022411 92 0.104
purine ribonucleotide catabolic process GO:0009154 404 0.102
microtubule polymerization or depolymerization GO:0031109 37 0.100
cell development GO:0048468 328 0.099
purine nucleoside triphosphate metabolic process GO:0009144 412 0.098
cell cell signaling GO:0007267 155 0.097
nucleoside monophosphate metabolic process GO:0009123 191 0.096
spindle organization GO:0007051 53 0.093
glycosyl compound catabolic process GO:1901658 413 0.089
negative regulation of cellular component organization GO:0051129 235 0.089
regulation of microtubule based process GO:0032886 74 0.086
ribonucleoside catabolic process GO:0042454 406 0.086
atp catabolic process GO:0006200 157 0.085
nucleus localization GO:0051647 1 0.080
cilium organization GO:0044782 68 0.079
protein polymerization GO:0051258 71 0.077
cellular macromolecular complex assembly GO:0034622 324 0.076
nucleoside catabolic process GO:0009164 408 0.075
cellular component assembly involved in morphogenesis GO:0010927 73 0.075
protein catabolic process GO:0030163 325 0.074
asymmetric neuroblast division GO:0055059 1 0.074
nucleotide catabolic process GO:0009166 408 0.073
positive regulation of catabolic process GO:0009896 310 0.072
meiosis i GO:0007127 4 0.072
regulation of mitosis GO:0007088 63 0.069
cell projection morphogenesis GO:0048858 129 0.069
Mouse
regulation of centrosome duplication GO:0010824 14 0.069
ribonucleoside triphosphate metabolic process GO:0009199 412 0.068
negative regulation of cell cycle process GO:0010948 121 0.068
Mouse
cell part morphogenesis GO:0032990 137 0.066
Mouse
regulation of meiotic cell cycle GO:0051445 4 0.065
macromolecular complex disassembly GO:0032984 60 0.063
double strand break repair via homologous recombination GO:0000724 50 0.062
spindle elongation GO:0051231 4 0.061
regulation of cell division GO:0051302 116 0.061
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.059
ribonucleoside monophosphate metabolic process GO:0009161 187 0.059
stem cell division GO:0017145 2 0.058
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.055
recombinational repair GO:0000725 50 0.055
positive regulation of organelle organization GO:0010638 195 0.054
positive regulation of hydrolase activity GO:0051345 331 0.054
positive regulation of cell cycle GO:0045787 140 0.054
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
post embryonic development GO:0009791 2 0.054
atp metabolic process GO:0046034 176 0.052
embryo development GO:0009790 123 0.051
Mouse
positive regulation of cellular catabolic process GO:0031331 284 0.051
negative regulation of proteolysis GO:0045861 132 0.046
single organism cellular localization GO:1902580 332 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
nervous system development GO:0007399 293 0.043
Mouse
double strand break repair GO:0006302 101 0.043
female gamete generation GO:0007292 2 0.043
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
Mouse
single organism reproductive process GO:0044702 98 0.041
cellular protein complex disassembly GO:0043624 36 0.041
regeneration GO:0031099 4 0.040
vesicle mediated transport GO:0016192 371 0.040
sister chromatid segregation GO:0000819 54 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
dna catabolic process GO:0006308 49 0.040
negative regulation of protein modification process GO:0031400 200 0.039
small gtpase mediated signal transduction GO:0007264 78 0.039
regulation of proteolysis GO:0030162 293 0.038
regulation of microtubule cytoskeleton organization GO:0070507 61 0.038
protein ubiquitination GO:0016567 314 0.037
maintenance of location in cell GO:0051651 62 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
regulation of centrosome cycle GO:0046605 15 0.036
protein processing GO:0016485 226 0.036
purine nucleoside monophosphate catabolic process GO:0009128 158 0.036
neuronal stem cell division GO:0036445 1 0.036
generation of neurons GO:0048699 152 0.035
maintenance of location GO:0051235 112 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.035
Mouse
negative regulation of catalytic activity GO:0043086 335 0.034
response to abiotic stimulus GO:0009628 336 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.033
neurogenesis GO:0022008 169 0.032
positive regulation of nucleotide catabolic process GO:0030813 185 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
protein depolymerization GO:0051261 30 0.031
establishment of nucleus localization GO:0040023 1 0.031
cellular ketone metabolic process GO:0042180 80 0.031
blastocyst development GO:0001824 3 0.030
positive regulation of dna metabolic process GO:0051054 73 0.029
regulation of protein localization GO:0032880 296 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.028
Mouse
meiotic nuclear division GO:0007126 10 0.028
tissue regeneration GO:0042246 3 0.028
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.028
protein maturation GO:0051604 233 0.028
attachment of spindle microtubules to kinetochore GO:0008608 17 0.027
regulation of cellular ketone metabolic process GO:0010565 50 0.027
oogenesis GO:0048477 2 0.027
negative regulation of protein maturation GO:1903318 142 0.027
regulation of cellular component movement GO:0051270 334 0.026
positive regulation of gtp catabolic process GO:0033126 166 0.026
negative regulation of protein depolymerization GO:1901880 17 0.026
cellular amino acid metabolic process GO:0006520 116 0.026
positive regulation of cell proliferation GO:0008284 301 0.026
cell fate determination GO:0001709 3 0.026
ras protein signal transduction GO:0007265 73 0.026
regulation of locomotion GO:0040012 329 0.026
regulation of cell motility GO:2000145 299 0.025
protein complex disassembly GO:0043241 52 0.025
regulation of protein processing GO:0070613 150 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
Mouse
proteasomal protein catabolic process GO:0010498 176 0.025
regulation of organelle assembly GO:1902115 40 0.025
mitotic sister chromatid segregation GO:0000070 53 0.025
regulation of proteasomal protein catabolic process GO:0061136 87 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
mitotic cell cycle phase transition GO:0044772 162 0.024
Mouse
regulation of cell cycle phase transition GO:1901987 126 0.024
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
regulation of dna metabolic process GO:0051052 153 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
cell morphogenesis GO:0000902 296 0.022
Mouse
chordate embryonic development GO:0043009 34 0.022
Mouse
positive regulation of programmed cell death GO:0043068 249 0.022
regulation of protein transport GO:0051223 213 0.022
negative regulation of chromosome organization GO:2001251 48 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
growth GO:0040007 202 0.021
Mouse
chromatin modification GO:0016568 298 0.021
wnt signaling pathway GO:0016055 156 0.021
microtubule bundle formation GO:0001578 15 0.021
positive regulation of cell cycle process GO:0090068 106 0.021
oxidation reduction process GO:0055114 396 0.021
regulation of cell migration GO:0030334 289 0.021
positive regulation of mitotic cell cycle GO:0045931 60 0.021
regulation of meiosis GO:0040020 3 0.021
protein localization to organelle GO:0033365 280 0.021
regulation of kinase activity GO:0043549 314 0.021
Mouse
microtubule based movement GO:0007018 32 0.021
regulation of transferase activity GO:0051338 355 0.021
Mouse
regulation of protein catabolic process GO:0042176 155 0.021
negative regulation of cell differentiation GO:0045596 171 0.020
spermatid development GO:0007286 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 206 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
negative regulation of catabolic process GO:0009895 104 0.020
negative regulation of developmental process GO:0051093 247 0.020
regulation of nuclear division GO:0051783 65 0.020
negative regulation of cell cycle GO:0045786 193 0.019
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
regulation of protein maturation GO:1903317 150 0.019
peptidyl serine phosphorylation GO:0018105 101 0.019
reproductive process GO:0022414 106 0.019
circulatory system development GO:0072359 262 0.019
Mouse
regulation of chromosome segregation GO:0051983 44 0.018
regulation of protein complex assembly GO:0043254 147 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
chromatin organization GO:0006325 351 0.018
male gamete generation GO:0048232 22 0.018
regulation of cellular response to stress GO:0080135 244 0.018
multicellular organismal aging GO:0010259 3 0.018
cell adhesion GO:0007155 325 0.018
negative regulation of cell division GO:0051782 31 0.018
cardiovascular system development GO:0072358 262 0.018
Mouse
chromosome separation GO:0051304 23 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
positive regulation of cell development GO:0010720 92 0.018
cellular amine metabolic process GO:0044106 41 0.017
mitotic centrosome separation GO:0007100 1 0.017
regulation of cell development GO:0060284 161 0.017
positive regulation of protein transport GO:0051222 135 0.017
intracellular protein transport GO:0006886 270 0.017
positive regulation of gtpase activity GO:0043547 166 0.017
protein targeting GO:0006605 187 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
spermatid differentiation GO:0048515 4 0.017
spindle assembly involved in mitosis GO:0090307 12 0.017
cellular component morphogenesis GO:0032989 314 0.017
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
negative regulation of protein processing GO:0010955 142 0.017
embryo development ending in birth or egg hatching GO:0009792 34 0.017
Mouse
guanosine containing compound catabolic process GO:1901069 239 0.017
cell projection organization GO:0030030 252 0.017
Mouse
system process GO:0003008 349 0.017
sister chromatid biorientation GO:0031134 2 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
cytokinesis GO:0000910 96 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
reciprocal meiotic recombination GO:0007131 4 0.016
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.016
regulation of protein ubiquitination GO:0031396 95 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
mitotic sister chromatid separation GO:0051306 18 0.016
developmental process involved in reproduction GO:0003006 66 0.016
positive regulation of transport GO:0051050 336 0.016
negative regulation of transferase activity GO:0051348 124 0.016
amine metabolic process GO:0009308 44 0.016
cilium morphogenesis GO:0060271 75 0.016
Mouse
biological adhesion GO:0022610 331 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
negative regulation of cell cycle phase transition GO:1901988 89 0.015
Mouse
reproduction GO:0000003 63 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
regulation of protein kinase activity GO:0045859 289 0.015
Mouse
cellular protein catabolic process GO:0044257 261 0.015
cellular response to oxidative stress GO:0034599 85 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
cell morphogenesis involved in differentiation GO:0000904 144 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
cell activation GO:0001775 213 0.015
oocyte development GO:0048599 1 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
nuclear migration GO:0007097 1 0.014
blood vessel morphogenesis GO:0048514 162 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
cytoplasmic transport GO:0016482 379 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
determination of adult lifespan GO:0008340 2 0.014
protein autophosphorylation GO:0046777 123 0.014
regulation of gtpase activity GO:0043087 180 0.014
positive regulation of developmental process GO:0051094 314 0.014
positive regulation of organelle assembly GO:1902117 17 0.013
regulation of neuroblast proliferation GO:1902692 3 0.013
head development GO:0060322 108 0.013
Mouse
positive regulation of cellular component organization GO:0051130 376 0.013
developmental growth GO:0048589 48 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
establishment of organelle localization GO:0051656 59 0.013
dna conformation change GO:0071103 113 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of mitotic cell cycle GO:0045930 102 0.013
Mouse
secretion GO:0046903 254 0.013
mitotic spindle elongation GO:0000022 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.012
regulation of neurogenesis GO:0050767 82 0.012
positive regulation of proteolysis GO:0045862 142 0.012
primary neural tube formation GO:0014020 3 0.012
Mouse
positive regulation of dna replication GO:0045740 35 0.012
regulation of sister chromatid segregation GO:0033045 27 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
meiotic cell cycle GO:0051321 13 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
actin filament based process GO:0030029 224 0.012
protein localization to nucleus GO:0034504 136 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
neuron differentiation GO:0030182 138 0.012
maintenance of protein location in cell GO:0032507 56 0.012
myeloid cell differentiation GO:0030099 117 0.012
multicellular organism reproduction GO:0032504 42 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
Mouse
signal transduction by phosphorylation GO:0023014 297 0.011
regulation of chromosome organization GO:0033044 103 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
dna recombination GO:0006310 77 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of dna replication GO:0006275 68 0.011
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
endomembrane system organization GO:0010256 196 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
response to oxidative stress GO:0006979 121 0.011
protein oligomerization GO:0051259 173 0.011
morphogenesis of an epithelium GO:0002009 60 0.011
Mouse
neuron development GO:0048666 113 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.010
regulation of neuron differentiation GO:0045664 70 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
Mouse
sex determination GO:0007530 3 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
multi organism reproductive process GO:0044703 54 0.010
tissue morphogenesis GO:0048729 96 0.010
Mouse
positive regulation of protein catabolic process GO:0045732 75 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
response to inorganic substance GO:0010035 127 0.010

STIL disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.438
congenital nervous system abnormality DOID:2490 21 0.438
microcephaly DOID:10907 6 0.065
immune system disease DOID:2914 155 0.041
disease of cellular proliferation DOID:14566 174 0.037
disease of metabolism DOID:0014667 295 0.019
inherited metabolic disorder DOID:655 242 0.019
hematopoietic system disease DOID:74 100 0.018
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013