Homo sapiens

6 known processes

KIAA0196

KIAA0196

(Aliases: SPG8,MGC111053)

KIAA0196 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endosomal transport GO:0016197 129 0.160
positive regulation of cellular component organization GO:0051130 376 0.102
ribonucleoside catabolic process GO:0042454 406 0.095
post embryonic development GO:0009791 2 0.094
vesicle mediated transport GO:0016192 371 0.094
nucleoside catabolic process GO:0009164 408 0.089
ribonucleoside triphosphate metabolic process GO:0009199 412 0.089
purine ribonucleoside catabolic process GO:0046130 398 0.069
cytoplasmic transport GO:0016482 379 0.066
ribonucleotide catabolic process GO:0009261 405 0.064
female gamete generation GO:0007292 2 0.063
purine ribonucleoside metabolic process GO:0046128 437 0.061
nucleoside triphosphate metabolic process GO:0009141 422 0.059
purine nucleoside triphosphate metabolic process GO:0009144 412 0.057
glycosyl compound catabolic process GO:1901658 413 0.053
membrane organization GO:0061024 292 0.052
ribonucleoside monophosphate metabolic process GO:0009161 187 0.049
purine nucleoside catabolic process GO:0006152 398 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.047
protein catabolic process GO:0030163 325 0.047
nucleoside triphosphate catabolic process GO:0009143 394 0.046
purine containing compound catabolic process GO:0072523 411 0.046
positive regulation of catabolic process GO:0009896 310 0.045
purine nucleotide catabolic process GO:0006195 405 0.042
purine nucleoside triphosphate catabolic process GO:0009146 392 0.041
nucleoside monophosphate metabolic process GO:0009123 191 0.041
negative regulation of programmed cell death GO:0043069 321 0.038
organophosphate catabolic process GO:0046434 430 0.037
intracellular protein transport GO:0006886 270 0.036
ion transmembrane transport GO:0034220 338 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
endomembrane system organization GO:0010256 196 0.035
actin filament based process GO:0030029 224 0.035
vacuolar transport GO:0007034 34 0.033
transmembrane transport GO:0055085 399 0.032
positive regulation of organelle organization GO:0010638 195 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.031
atp metabolic process GO:0046034 176 0.030
cellular response to dna damage stimulus GO:0006974 379 0.028
protein localization to organelle GO:0033365 280 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
single organism membrane organization GO:0044802 268 0.027
covalent chromatin modification GO:0016569 254 0.027
rho protein signal transduction GO:0007266 26 0.027
locomotory behavior GO:0007626 1 0.027
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
determination of adult lifespan GO:0008340 2 0.025
protein localization to membrane GO:0072657 160 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
purine nucleoside monophosphate metabolic process GO:0009126 186 0.024
cation transmembrane transport GO:0098655 238 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
modification dependent protein catabolic process GO:0019941 209 0.023
endocytosis GO:0006897 159 0.023
single organism membrane fusion GO:0044801 37 0.022
spermatid development GO:0007286 4 0.022
cellular amine metabolic process GO:0044106 41 0.022
positive regulation of developmental process GO:0051094 314 0.022
organic anion transport GO:0015711 103 0.022
nucleotide catabolic process GO:0009166 408 0.021
regulation of protein transport GO:0051223 213 0.021
positive regulation of transport GO:0051050 336 0.021
multicellular organismal aging GO:0010259 3 0.021
spermatid differentiation GO:0048515 4 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
adult locomotory behavior GO:0008344 1 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.021
regulation of cytokine production GO:0001817 232 0.020
oogenesis GO:0048477 2 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
atp catabolic process GO:0006200 157 0.020
angiogenesis GO:0001525 147 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.019
mitotic cell cycle GO:0000278 326 0.019
negative regulation of cell death GO:0060548 345 0.019
ras protein signal transduction GO:0007265 73 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
cellular homeostasis GO:0019725 196 0.019
retrograde transport endosome to golgi GO:0042147 45 0.019
amine metabolic process GO:0009308 44 0.019
cell projection organization GO:0030030 252 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
response to biotic stimulus GO:0009607 276 0.018
dna repair GO:0006281 198 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
regulation of vasculature development GO:1901342 97 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
single organism cellular localization GO:1902580 332 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
anion transport GO:0006820 161 0.017
regulation of transferase activity GO:0051338 355 0.017
cellular protein catabolic process GO:0044257 261 0.017
engulfment of apoptotic cell GO:0043652 2 0.017
nervous system development GO:0007399 293 0.017
response to other organism GO:0051707 261 0.017
regulation of cytoskeleton organization GO:0051493 177 0.017
response to oxygen containing compound GO:1901700 369 0.017
cellular ketone metabolic process GO:0042180 80 0.017
circulatory system development GO:0072359 262 0.017
cellular component morphogenesis GO:0032989 314 0.016
regulation of proteolysis GO:0030162 293 0.016
regulation of intracellular transport GO:0032386 195 0.016
blood vessel development GO:0001568 172 0.016
regulation of dna metabolic process GO:0051052 153 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
segmentation GO:0035282 4 0.016
oocyte differentiation GO:0009994 2 0.016
innate immune response GO:0045087 178 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
positive regulation of protein catabolic process GO:0045732 75 0.016
cellular lipid metabolic process GO:0044255 303 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.015
oocyte development GO:0048599 1 0.015
regulation of angiogenesis GO:0045765 92 0.015
positive regulation of immune system process GO:0002684 283 0.015
apoptotic signaling pathway GO:0097190 268 0.015
chromatin organization GO:0006325 351 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
blood vessel morphogenesis GO:0048514 162 0.015
response to external biotic stimulus GO:0043207 261 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
gtp catabolic process GO:0006184 237 0.015
vasculature development GO:0001944 181 0.015
cation transport GO:0006812 331 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
cytokine production GO:0001816 247 0.015
cell division GO:0051301 168 0.015
immune response GO:0006955 307 0.015
cellular amino acid metabolic process GO:0006520 116 0.014
lysosomal transport GO:0007041 33 0.014
chromatin modification GO:0016568 298 0.014
cell morphogenesis GO:0000902 296 0.014
tripartite regional subdivision GO:0007351 2 0.014
rna interference GO:0016246 4 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
dephosphorylation GO:0016311 209 0.014
mitochondrion organization GO:0007005 156 0.014
cell part morphogenesis GO:0032990 137 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
cell cycle phase transition GO:0044770 173 0.014
dna conformation change GO:0071103 113 0.014
cation homeostasis GO:0055080 189 0.014
neuron development GO:0048666 113 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of protein complex assembly GO:0043254 147 0.014
epithelial cell proliferation GO:0050673 128 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
generation of neurons GO:0048699 152 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
membrane fusion GO:0061025 43 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
double strand break repair GO:0006302 101 0.013
protein oligomerization GO:0051259 173 0.013
secretion GO:0046903 254 0.013
response to bacterium GO:0009617 144 0.013
protein targeting GO:0006605 187 0.013
single organism reproductive process GO:0044702 98 0.013
organelle fusion GO:0048284 36 0.013
chemical homeostasis GO:0048878 306 0.013
wound healing GO:0042060 115 0.013
reproduction GO:0000003 63 0.013
regulation of growth GO:0040008 165 0.013
blastoderm segmentation GO:0007350 2 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
alcohol metabolic process GO:0006066 114 0.013
lipid biosynthetic process GO:0008610 177 0.013
actin cytoskeleton organization GO:0030036 207 0.013
cellular protein complex assembly GO:0043623 188 0.013
positive regulation of protein complex assembly GO:0031334 86 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
actin filament organization GO:0007015 128 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
microtubule based movement GO:0007018 32 0.012
nuclear transport GO:0051169 179 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
regulation of cell cycle GO:0051726 393 0.012
endosome to lysosome transport GO:0008333 21 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
cell development GO:0048468 328 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
cytokinesis GO:0000910 96 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
photoreceptor cell differentiation GO:0046530 2 0.011
regulation of gtpase activity GO:0043087 180 0.011
growth GO:0040007 202 0.011
methylation GO:0032259 106 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
regulation of cellular component movement GO:0051270 334 0.011
hemopoiesis GO:0030097 180 0.011
cell type specific apoptotic process GO:0097285 125 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
defense response GO:0006952 315 0.011
lipid metabolic process GO:0006629 381 0.011
monocarboxylic acid biosynthetic process GO:0072330 67 0.011
regulation of locomotion GO:0040012 329 0.011
organic acid transport GO:0015849 65 0.011
negative regulation of protein modification process GO:0031400 200 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
protein deubiquitination GO:0016579 79 0.011
tissue regeneration GO:0042246 3 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
negative regulation of organelle organization GO:0010639 126 0.011
lipid localization GO:0010876 106 0.011
cellular cation homeostasis GO:0030003 163 0.011
carbohydrate metabolic process GO:0005975 207 0.011
positive regulation of transferase activity GO:0051347 227 0.011
regulation of kinase activity GO:0043549 314 0.011
nitrogen compound transport GO:0071705 191 0.011
neuromuscular junction development GO:0007528 3 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
receptor mediated endocytosis GO:0006898 84 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
monovalent inorganic cation transport GO:0015672 128 0.010
mitochondrial transport GO:0006839 60 0.010
dendritic spine morphogenesis GO:0060997 3 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
axon cargo transport GO:0008088 2 0.010
cell projection morphogenesis GO:0048858 129 0.010

KIAA0196 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.038
nervous system disease DOID:863 431 0.038
disease of metabolism DOID:0014667 295 0.029
inherited metabolic disorder DOID:655 242 0.023
musculoskeletal system disease DOID:17 223 0.023
disease of cellular proliferation DOID:14566 174 0.022
cancer DOID:162 167 0.022
organ system cancer DOID:0050686 164 0.022
carbohydrate metabolic disorder DOID:2978 55 0.014
brain disease DOID:936 73 0.011
hereditary spastic paraplegia DOID:2476 19 0.002
paraplegia DOID:607 19 0.002