Homo sapiens

16 known processes

UBA2

ubiquitin-like modifier activating enzyme 2

(Aliases: ARX,SAE2,FLJ13058)

UBA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear export GO:0051168 69 0.518
cellular response to endogenous stimulus GO:0071495 336 0.424
chromatin organization GO:0006325 351 0.396
nervous system development GO:0007399 293 0.351
regulation of cellular ketone metabolic process GO:0010565 50 0.254
post embryonic development GO:0009791 2 0.253
female gamete generation GO:0007292 2 0.239
regulation of cell cycle GO:0051726 393 0.216
rna export from nucleus GO:0006405 33 0.200
establishment of rna localization GO:0051236 39 0.167
mitotic cell cycle process GO:1903047 286 0.156
dna conformation change GO:0071103 113 0.153
nucleobase containing compound transport GO:0015931 51 0.148
nucleocytoplasmic transport GO:0006913 176 0.147
protein modification by small protein conjugation GO:0032446 342 0.144
gene silencing by rna GO:0031047 26 0.143
somitogenesis GO:0001756 2 0.128
neurogenesis GO:0022008 169 0.121
nitrogen compound transport GO:0071705 191 0.120
protein sumoylation GO:0016925 25 0.119
generation of precursor metabolites and energy GO:0006091 68 0.115
nuclear transport GO:0051169 179 0.115
mitotic cell cycle GO:0000278 326 0.108
microtubule based process GO:0007017 210 0.105
positive regulation of proteolysis GO:0045862 142 0.101
posttranscriptional regulation of gene expression GO:0010608 213 0.101
cell morphogenesis GO:0000902 296 0.100
vesicle mediated transport GO:0016192 371 0.099
amine metabolic process GO:0009308 44 0.098
oocyte differentiation GO:0009994 2 0.097
regulation of proteasomal protein catabolic process GO:0061136 87 0.097
positive regulation of transferase activity GO:0051347 227 0.096
organophosphate biosynthetic process GO:0090407 163 0.090
taxis GO:0042330 157 0.089
neuron development GO:0048666 113 0.087
embryo development GO:0009790 123 0.086
positive regulation of cellular component biogenesis GO:0044089 158 0.085
microtubule cytoskeleton organization GO:0000226 176 0.081
neuron projection development GO:0031175 106 0.078
cellular amino acid metabolic process GO:0006520 116 0.076
cell morphogenesis involved in differentiation GO:0000904 144 0.075
cell part morphogenesis GO:0032990 137 0.069
oocyte development GO:0048599 1 0.068
neuromuscular junction development GO:0007528 3 0.065
meiotic nuclear division GO:0007126 10 0.064
regulation of proteolysis GO:0030162 293 0.063
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.062
regulation of cell differentiation GO:0045595 393 0.062
posttranscriptional gene silencing GO:0016441 25 0.060
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.059
regulation of mitotic cell cycle GO:0007346 189 0.059
cytoplasmic transport GO:0016482 379 0.059
activation of cysteine type endopeptidase activity GO:0097202 57 0.055
nuclear division GO:0000280 128 0.055
regulation of transferase activity GO:0051338 355 0.055
mrna processing GO:0006397 133 0.054
nls bearing protein import into nucleus GO:0006607 2 0.054
hemopoiesis GO:0030097 180 0.053
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.053
rna localization GO:0006403 41 0.053
regulation of cellular amine metabolic process GO:0033238 11 0.053
cell projection morphogenesis GO:0048858 129 0.052
regulation of meiosis GO:0040020 3 0.051
regulation of peptidase activity GO:0052547 180 0.051
negative regulation of catalytic activity GO:0043086 335 0.051
rna transport GO:0050658 39 0.050
single organism cell adhesion GO:0098602 179 0.048
cellular response to hormone stimulus GO:0032870 125 0.048
negative regulation of transferase activity GO:0051348 124 0.047
generation of neurons GO:0048699 152 0.047
regulation of cellular component biogenesis GO:0044087 281 0.046
response to oxygen containing compound GO:1901700 369 0.046
cellular macromolecular complex assembly GO:0034622 324 0.046
oogenesis GO:0048477 2 0.045
cell cycle phase transition GO:0044770 173 0.045
chromatin assembly or disassembly GO:0006333 78 0.045
organonitrogen compound biosynthetic process GO:1901566 200 0.044
protein methylation GO:0006479 74 0.044
positive regulation of phosphorylation GO:0042327 394 0.044
reproductive process GO:0022414 106 0.043
determination of adult lifespan GO:0008340 2 0.043
negative regulation of phosphorus metabolic process GO:0010563 267 0.043
developmental process involved in reproduction GO:0003006 66 0.042
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.041
cellular response to oxygen containing compound GO:1901701 276 0.041
negative regulation of locomotion GO:0040013 118 0.040
cell cycle checkpoint GO:0000075 117 0.040
cell division GO:0051301 168 0.039
regulation of nuclear division GO:0051783 65 0.039
enzyme linked receptor protein signaling pathway GO:0007167 303 0.038
sulfur amino acid biosynthetic process GO:0000097 6 0.036
cell development GO:0048468 328 0.036
regulation of cellular component movement GO:0051270 334 0.036
embryo development ending in birth or egg hatching GO:0009792 34 0.035
mitotic cell cycle phase transition GO:0044772 162 0.035
mitotic nuclear division GO:0007067 119 0.035
carbohydrate metabolic process GO:0005975 207 0.035
regulation of neuron death GO:1901214 56 0.034
neuron differentiation GO:0030182 138 0.034
multicellular organismal reproductive process GO:0048609 40 0.034
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
locomotory behavior GO:0007626 1 0.033
negative regulation of protein modification process GO:0031400 200 0.033
negative regulation of kinase activity GO:0033673 106 0.032
organelle fission GO:0048285 149 0.032
cellular amine metabolic process GO:0044106 41 0.032
cellular lipid metabolic process GO:0044255 303 0.032
signal transduction by phosphorylation GO:0023014 297 0.032
cellular component morphogenesis GO:0032989 314 0.031
rna interference GO:0016246 4 0.031
multicellular organism reproduction GO:0032504 42 0.030
negative regulation of binding GO:0051100 57 0.030
organelle assembly GO:0070925 176 0.030
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.030
single organism reproductive process GO:0044702 98 0.030
positive regulation of hydrolase activity GO:0051345 331 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
axon regeneration GO:0031103 1 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
cell projection organization GO:0030030 252 0.029
nucleic acid transport GO:0050657 39 0.028
regulation of protein kinase activity GO:0045859 289 0.028
negative regulation of cell migration GO:0030336 102 0.028
mitotic sister chromatid segregation GO:0000070 53 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
regulation of protein catabolic process GO:0042176 155 0.027
response to organic cyclic compound GO:0014070 204 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
regulation of cell cycle process GO:0010564 266 0.027
protein maturation GO:0051604 233 0.026
sex differentiation GO:0007548 45 0.026
reproduction GO:0000003 63 0.026
multicellular organismal aging GO:0010259 3 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.026
regulation of locomotion GO:0040012 329 0.026
chromatin modification GO:0016568 298 0.025
cellular response to lipid GO:0071396 127 0.025
intracellular receptor signaling pathway GO:0030522 104 0.025
regulation of cell cycle phase transition GO:1901987 126 0.025
secretion GO:0046903 254 0.024
mapk cascade GO:0000165 288 0.024
regulation of kinase activity GO:0043549 314 0.024
single organism cellular localization GO:1902580 332 0.024
dna integrity checkpoint GO:0031570 71 0.024
dendritic spine organization GO:0097061 4 0.024
regulation of cell motility GO:2000145 299 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.023
response to acid chemical GO:0001101 66 0.023
central nervous system neuron axonogenesis GO:0021955 3 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
regulation of protein ubiquitination GO:0031396 95 0.023
regulation of meiotic cell cycle GO:0051445 4 0.023
meiotic chromosome segregation GO:0045132 4 0.023
biological adhesion GO:0022610 331 0.022
ribonucleoprotein complex subunit organization GO:0071826 81 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
negative regulation of cellular component movement GO:0051271 106 0.022
neuron projection morphogenesis GO:0048812 50 0.022
interspecies interaction between organisms GO:0044419 156 0.022
regulation of cell migration GO:0030334 289 0.022
internal protein amino acid acetylation GO:0006475 101 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
ribosome biogenesis GO:0042254 48 0.021
protein modification by small protein removal GO:0070646 92 0.021
single organism nuclear import GO:1902593 104 0.021
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
rna processing GO:0006396 255 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
apoptotic signaling pathway GO:0097190 268 0.020
purine nucleotide biosynthetic process GO:0006164 84 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
positive regulation of cell death GO:0010942 263 0.020
multi organism reproductive process GO:0044703 54 0.020
regeneration GO:0031099 4 0.020
organic acid biosynthetic process GO:0016053 97 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
protein import into nucleus GO:0006606 104 0.019
response to abiotic stimulus GO:0009628 336 0.019
response to transforming growth factor beta GO:0071559 94 0.019
response to hormone GO:0009725 175 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.019
spermatid development GO:0007286 4 0.019
muscle structure development GO:0061061 98 0.018
negative regulation of neuron apoptotic process GO:0043524 23 0.018
chromosome segregation GO:0007059 114 0.018
dna geometric change GO:0032392 32 0.018
regulation of cellular protein catabolic process GO:1903362 96 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.017
negative regulation of protein maturation GO:1903318 142 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
small molecule biosynthetic process GO:0044283 157 0.017
tissue migration GO:0090130 119 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
peptidyl lysine acetylation GO:0018394 101 0.017
regulation of cellular response to stress GO:0080135 244 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
cellular ketone metabolic process GO:0042180 80 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
endomembrane system organization GO:0010256 196 0.016
protein dna complex assembly GO:0065004 64 0.016
glycerophospholipid metabolic process GO:0006650 84 0.016
tube development GO:0035295 125 0.016
regulation of mapk cascade GO:0043408 262 0.016
response to other organism GO:0051707 261 0.015
response to growth factor GO:0070848 205 0.015
execution phase of apoptosis GO:0097194 32 0.015
chemotaxis GO:0006935 157 0.015
mrna metabolic process GO:0016071 175 0.015
covalent chromatin modification GO:0016569 254 0.015
reproductive structure development GO:0048608 55 0.015
receptor mediated endocytosis GO:0006898 84 0.015
cell type specific apoptotic process GO:0097285 125 0.015
negative regulation of cell proliferation GO:0008285 228 0.014
cellular response to organic cyclic compound GO:0071407 127 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
positive regulation of endopeptidase activity GO:0010950 84 0.014
ribonucleoprotein complex localization GO:0071166 4 0.014
cellular response to organonitrogen compound GO:0071417 124 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
gonad development GO:0008406 34 0.014
sister chromatid segregation GO:0000819 54 0.014
intracellular protein transport GO:0006886 270 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
development of primary sexual characteristics GO:0045137 35 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
regulation of binding GO:0051098 111 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
regulation of neuron apoptotic process GO:0043523 35 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
protein catabolic process GO:0030163 325 0.013
posttranscriptional gene silencing by rna GO:0035194 25 0.013
endocytosis GO:0006897 159 0.013
positive regulation of kinase activity GO:0033674 204 0.013
reproductive system development GO:0061458 56 0.013
neuron death GO:0070997 65 0.013
regulation of viral process GO:0050792 103 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
rna splicing via transesterification reactions GO:0000375 90 0.013
regulation of cell growth GO:0001558 135 0.013
nuclear body organization GO:0030575 4 0.013
epithelium migration GO:0090132 119 0.013
purine containing compound biosynthetic process GO:0072522 88 0.012
chromatin remodeling GO:0006338 55 0.012
cellular protein complex assembly GO:0043623 188 0.012
defense response GO:0006952 315 0.012
histone methylation GO:0016571 60 0.012
negative regulation of protein ubiquitination GO:0031397 35 0.012
mitotic spindle organization GO:0007052 27 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
regulation of nervous system development GO:0051960 88 0.012
ameboidal type cell migration GO:0001667 135 0.012
dna damage checkpoint GO:0000077 68 0.012
sulfur compound metabolic process GO:0006790 101 0.012
negative regulation of cell death GO:0060548 345 0.012
neural crest formation GO:0014029 2 0.012
response to organonitrogen compound GO:0010243 156 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.011
sexual reproduction GO:0019953 37 0.011
head development GO:0060322 108 0.011
cell growth GO:0016049 160 0.011
cellular protein catabolic process GO:0044257 261 0.011
negative regulation of cell motility GO:2000146 104 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
immune system development GO:0002520 195 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of cell development GO:0060284 161 0.011
protein o linked glycosylation GO:0006493 21 0.011
positive regulation of protein kinase activity GO:0045860 190 0.010
ribonucleoprotein complex assembly GO:0022618 78 0.010
phospholipid metabolic process GO:0006644 99 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
protein export from nucleus GO:0006611 29 0.010
single organism membrane organization GO:0044802 268 0.010
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.010

UBA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.092
inherited metabolic disorder DOID:655 242 0.092
disease of mental health DOID:150 70 0.013
developmental disorder of mental health DOID:0060037 29 0.013
musculoskeletal system disease DOID:17 223 0.012