|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.995
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.963
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.940
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.911
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.653
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
10 |
0.357
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.350
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.347
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.336
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.300
|
Mouse |
|
|
endosome to lysosome transport
|
GO:0008333 |
21 |
0.278
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.228
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.214
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.145
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.125
|
Mouse |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.098
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.089
|
Mouse |
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.080
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.075
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.070
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.064
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.061
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.059
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.057
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.056
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.054
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.054
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.053
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.052
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.052
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.050
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.045
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.044
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.043
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.043
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.042
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.039
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.038
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.038
|
|
|
|
memory
|
GO:0007613 |
3 |
0.038
|
|
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.037
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.037
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.036
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.035
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.034
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.033
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.033
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.033
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.033
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.032
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.032
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.031
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.030
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.030
|
|
|
|
growth
|
GO:0040007 |
202 |
0.030
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.029
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.029
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.028
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.028
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.027
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.027
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.026
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.026
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.026
|
|
|
|
isg15 protein conjugation
|
GO:0032020 |
5 |
0.026
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.026
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.025
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.025
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.025
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.024
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.024
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.024
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.024
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.023
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.023
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.023
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.022
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.022
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.022
|
Mouse |
|
|
long term memory
|
GO:0007616 |
2 |
0.022
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.022
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.022
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.021
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.021
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.021
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.020
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.020
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.020
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.020
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.020
|
|
|
|
system process
|
GO:0003008 |
349 |
0.020
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.019
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.019
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.019
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.019
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.019
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.019
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.018
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.018
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.018
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.018
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.017
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.017
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.017
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.017
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.017
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.017
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.016
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.016
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.016
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.016
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.015
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.015
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.015
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.015
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.015
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.015
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.014
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.014
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.014
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.014
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.014
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.014
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.014
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.014
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.013
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.013
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.013
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.013
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.013
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.013
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.013
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.013
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.013
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.013
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.013
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.013
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.012
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.012
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.012
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.012
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.012
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.012
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.012
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.012
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.012
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.012
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.012
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.012
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.011
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.011
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.011
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.011
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.011
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.011
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.011
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.011
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.011
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.011
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.011
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.011
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.011
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.011
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.011
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.011
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.010
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.010
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.010
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.010
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.010
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.010
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.010
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.010
|
|